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The Mystery of the Blue Death

A Case Study in Epidemiology and the History of Science

By Susan Bandoni Muench

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The Mystery of the Blue Death

This historical case study describes the story of John Snow’s discovery of water-borne transmission of cholera in 19th-century London. Designed for use in a Global Health class, the case explores cholera outbreaks and their causes as well as models of disease. In addition, the case provides a framework for discussing the nature of science, particularly non-experimental tests of hypotheses, the cultural context of science, and populational thinking. The case could be used in a variety of other contexts, including courses in microbiology and introductory biology for either majors or non-majors. Because it addresses the nature of science, it is also appropriate for courses in the history, philosophy, or sociology of science.

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Date Posted

  • Apply terminology and concepts from epidemiology and public health to a case study.
  • Explore aspects of the nature of science, including the role of models in hypothesis testing, non-experimental tests of hypotheses, and populational thinking.
  • Explore the relationship between science and the surrounding culture, and cultural and class influences on the practice of science.

Cholera; Vibrio cholera; diarrheal disease; infectious disease; water-borne disease; models of disease; epidemiological methods; experimental design; hypothesis testing; populational thinking; health inequities; John Snow; London

  

Subject Headings

EDUCATIONAL LEVEL

High school, Undergraduate lower division, Undergraduate upper division, Graduate, Professional (degree program)

TOPICAL AREAS

History of science, Scientific method, Social issues, Social justice issues

TYPE/METHODS

Teaching Notes & Answer Key

Teaching notes.

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Teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources.

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Answer Keys are protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, purchase a subscription here .

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Materials & Media

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IMAGES

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COMMENTS

  1. Can Water Kill Case Study Answers

    3. Keeping in mind your answers to questions 1 and 2, what do you think the immediate cause of death was for Jennifer, Cassandra, and James? I believe that the immediate cause of death for them was swelling of the brain. 4. If you suspected that a patient's symptoms were caused by the condition suffered by

  2. Key

    Case Study - Water Can Kill. Three True Stories. Case 1: Jennifer Strange was a 28-year-old mother of three who entered a radio contest to try to win a Nintendo Wii game system for her children. As part of KDND's "Hold your wee for a Wii" contest, Jennifer drank bottle after bottle of water for hours without urinating.

  3. Lab 1 Osmosis Water can kill. Flashcards

    The environment would become hypotonic, causing water to move into the cell and the cell would swell. Estimate how much the brain would swell due to osmosis if the concentration of the cerebrospinal fluid fell to 280 mM. In other words, find what the new volume of the brain would be once equilibrium was reestablished. 1,285 cm^3.

  4. Case Study Water Can Kill Homework Worksheet

    Keeping in mind your answer to question 1 and the concepts discussed in the reading for today's lab: a. What do you think the immediate cause of death was for Jennifer and James? Heat stroke, Water intoxication, brain damage, Seizure, oxygen loss. b. What kind of test would you run to confirm your suspicions?

  5. Water Can Kill?

    Abstract. This case study presents three true stories of people who suffered fatal hyponatremia (low sodium concentration in their body fluids) after consuming excessive amounts of water. Students examine the tonicity of the extracellular environment created by this water consumption, the effect this has on cells and how this impacts different ...

  6. PDF Water can kill?

    Jennifer's mother found her that afternoon, dead in her home. Case 2: Cassandra Killpack 3. After a 3 1⁄2-week trial, a jury found Jennete Killpack, 29, guilty of killing her 4-year-old adopted daughter Cassandra by forcing approximately a gallon of water down the girl's throat in an attempt to discipline her.

  7. PDF Death by Osmosis: An interactive, investigative laboratory exercise

    Department of Biology Hastings College 700 Turner Avenue Hastings, NE 68901 [email protected]. William Beachly is an assistant professor who teaches courses in Principles of Biology (a two-semester major's course), Human Physiology, Ecology, Animal Behavior, and Invertebrates. Reprinted From: Beachly, W. M. 2000.

  8. LAB 1: OSMOSIS CASE STUDY Flashcards

    Study with Quizlet and memorize flashcards containing terms like what sort of environment does consuming excessive amounts of pure water create in the body fluid that surrounds your cells, what effect would consuming excessive amounts of pure water have on your cells, what types of symptoms did Jennifer, Cassandra, and James have in common? and more.

  9. Case Study #1 Lost in the Desert Flashcards

    Antidiuretic Hormone (ADH) Extreme water loss may cause increased osmolality stimulating a release of ADH. This stimulates water reabsorption in the DCT and collecting ducts of the nephrons. This increase water retention, decreasing urine production and decreasing blood volume. ANOTHER ANSWER TO CARD #4.

  10. Can Water Kill

    Keeping in mind your answers to questions 1 and 2, what do you think the immediate cause of death was for; Jennifer, Cassandra, and James? There was most likely an imbalance of fluids in their cells which caused them to die, the brain swelled. If you suspected that a patient's symptoms were caused by the condition suffered by Jennifer ...

  11. Solved NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE

    Case 3: James McBride James McBride, a 25-year-old police officer, died after a 12-mile bike ride that was part of a training course. Over the course of the ride, James drank roughly three gallons of water that he brought with him in a pack. During a session that focused on how to dismount a bike, an instructor noticed that McBride looked ill ...

  12. The Mystery of the Blue Death

    Abstract. This historical case study describes the story of John Snow's discovery of water-borne transmission of cholera in 19th-century London. Designed for use in a Global Health class, the case explores cholera outbreaks and their causes as well as models of disease. In addition, the case provides a framework for discussing the nature of ...

  13. Death by Water Intoxication

    Description. This science article / sub plan comes in two versions (with answer key): 1) easily printable PDFs, as well as 2) Google Slides for distance learning. Students can type in their answers directly in the Google Slides. This resource spans two pages in total with 1 and 1/3 pages of article and 2/3 pages of questions.

  14. topic 4.4: water pollution

    cause the death of many fish and stick to the feathers of seabirds causing them to lose the ability to fly.2. Fertilizer Some wastewater, fertilizers and sewage contain high levels of nutrients. If they end up in water bodies, they encourage algae and weed growth in the water. This will make the water undrinkable, and even clog filters.

  15. Case Study (CS) Quiz 7

    Study with Quizlet and memorize flashcards containing terms like To finish the following sentence, select all that apply: The temperature of the water likely caused______________. (a) decreased blood pressure (b) perspiration (c) rehydration (d) vasoconstriction, Consider for a moment, what you learned from the "Blood Everywhere" case study... Given the circumstances of their death, would you ...

  16. Water Can Kill Questions PDF

    5. You would need to administer a saline (hypertonic) solution via an IV. 6. The saline solution causes the water to exit the cells. Part II Questions 1. Vasopressin would cause less water to exit the body, so when athletes continue to hydrate, their body retains water, putting them at risk for developing hyponatremia. 2.

  17. Osmosis and Tonicity

    An introduction to osmosis, tonicity and the terms hypotonic, hypertonic, isotonic, and semipermeable membrane. Students read fictional case studies of people dying of water intoxication and hypothesize about why the people die. A follow-up instructional worksheet guides students to a basic understanding of osmosis and tonicity.

  18. The Hot Tub Mystery: The Story of a Very HOT Tub

    7. Blood viscosity. - Overall from the evidence we have gathered we believe the death resulted from a combination of being dehydrated from extreamly hot water and adding alcohol with that. 1. Sympathetic Nervous System affects vessel diameter; vasoconstriction= more resistance and increased blood pressure. 2.

  19. Key

    Case Study - Water Can Kill. Three True Stories. Case 1: Jennifer Strange was a 28-year-old mother of three who entered a radio contest to try to win a Nintendo Wii game system for her children. As part of KDND's "Hold your wee for a Wii" contest, Jennifer drank bottle after bottle of water for hours without urinating.

  20. PDF Streams of Coal or Streams of Death? A Toxicology Case Study

    A Toxicology Case Study. by. Linda Niedziela. Biology Department Elon University, Elon, NC. Part I— Remembering. The following case is based on a true story that took place around the year 1982. Mary Beth watched the children splash in the cool, clear water of a stream at Yellow Creek State Recreation Park.

  21. The Mystery of the Blue Death: A Case Study in Epidemiology ...

    The start of illness could be tracked to common water sources Those that were sick and using the same water source would be evidence Breathing the same air would also act as a constant See an expert-written answer!