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Participate In Paid Studies

Are you interested in participating in psychological research and at the same time getting compensated for your time? If so, there are many studies being conducted year round by New York University’s Department of Psychology faculty and doctoral students that offer monetary compensation.

What to Expect

  • The Department of Psychology faculty and doctoral students have diverse research interests. As a prospective participant, you will have the opportunity to participate in research studies that encompass areas such as visual perception and attention, decision-making, language acquisition, learning and memory and social cognitive processes.   
  • All NYU studies have formal approval from the University’s Institutional Review Board known as the University Committee on Activities Involving Human Subjects (UCAIHS).
  • Most studies are in-person lab studies that take place at  6 Washington Place .
  • Studies are non-invasive and many involve completing computer tasks, responding to stimuli presented and/or filling out questionnaires.
  • The time commitment for each study varies. Many studies require one visit ranging from 30 minutes to 2 hours, and some may be of longer duration or require multiple visits.
  • Payment generally ranges from $10/hr to $20/hr.
  • In addition to monetary compensation, some studies offer food and/or free merchandise.
  • Each study has its own specific eligibility requirements, but ALL paid studies require prospective participants to be at least 18 years old.

Signing Up for a Paid Study

Below are paid studies currently available in the Department of Psychology or at NYU Langone Health.  You may also sign-up for Department of Psychology paid studies on the  NYU Paid Psychology Research Sign-Up System .

Cumulative Allocation of Resources

 IRB-FY2022-6764

Laurence T. Maloney 

To better understand how people make decisions now reaching into the future 


You will play simple video games. 


One hour 


208 C, Meyer Building, 6 Washington Place


Age 18 or older


$12/hour and a bonus up to $50 for good performance

Name: Lilly Li

Email: [email protected] 

OPTIMIZING EXERCISE FOR THE TREATMENT OF ANXIETY

 i20-01348 

Kristin Szuhany 

The purpose of this study is to learn about the effects of different exercise regimens on anxiety and exercise engagement and adherence. If you are eligible for this study, you will complete a 2-month exercise intervention and 2 follow-up assessments (total duration 5-6 months). The exercise intervention will either include low intensity exercise only or a titration program in which you will start at low intensity exercise and work your way up to high intensity exercise. We also provide treatment referrals. 

Your information will remain private.

You will receive compensation for your time. 

To learn more about the study and to see if it is something you would be interested in and a good fit for, please fill out the following survey: .

:

Research Coordinator, Giselle Cornejo; 646 754-4773; .

Randomized Placebo-Controlled Trial to Determine the Biological Signature of Cannabidiol as a Treatment for Social Anxiety Disorder

 i22-00568 

Kristin Szuhany 

The purpose of this research study is to determine whether cannabidiol (CBD), a non-psychoactive part of cannabis, is an effective treatment for social anxiety disorder (SAD), and to better understand how CBD might improve SAD symptoms. After medical and psychiatric evaluations are completed, eligible participants are randomly assigned (that is, by chance) to one of two treatments lasting approximately 3 weeks: CBD or placebo. The study will last about 1-2 months and full participation includes 6 study visits as well as fMRI neuroimaging scans, a stress task, and blood tests. Eligible participants receive compensation for time completing study assessments.


To learn more about the study and to see if it is something you would be interested in and a good fit for, please fill out the following survey: .

Research Coordinator, Haley Ward; 646-754-4507;

The Role of Exercise in the Consolidation of Fear Extinction Learning in Adults with High Anxiety Sensitivity

 i21-01657 

Kristin Szuhany 

The purpose of this study is to investigate differences in extinction learning (measured by skin conductance [sweating] and heart rate) in adults with high anxiety sensitivity and anxiety disorders following exercise or sitting. If you are eligible for this study after 1 screening visit, you will complete a 3-day emotional learning experiment. You will be randomly assigned (like the flip of a coin) to either exercise at moderate intensity or sit for 20 minutes after the emotional learning experiment on Day 2. This research study involves 4 in-person visits total (the 3 experimental visits and 1 screening visit beforehand). This is not a treatment study.

Your information will remain private.

You will receive compensation for your time. 

To learn more about the study and to see if it is something you would be interested in and a good fit for, please fill out the following survey: .

:

Research Coordinator, Giselle Cornejo; 646-754-4773; .

Do you have depression?

Do you have depression?

If so, you might be eligible for a research study at NYU Langone Health to understand more about your symptoms, behavior, and brain function. 


· You must be between 18 and 55 years old and in good physical health. 

· Participation includes 1-3 appointments, including a functional magnetic resonance imaging (fmri) scan, for a total of 6-12 hours.

$25/hour

For more information about this study, please call 646-754-4471 or email  or visit .

Do you have Obsessive Compulsive Disorder?

If so, you might be eligible for a research study investigating the effects of transcranial magnetic stimulation (TMS) on brain function in the disorder at the Nathan Kline Institute (NKI).


· You must be between 18 and 55 years old and in good physical health. 

· Have OCD

· 1 remote screening appointment and 3 in-person appointments to NKI

· We will ask you about your health and to fill out some questionnaires about your symptoms

· During each in-person appointment, you will perform a computer task while having your brain activity measured using functional magnetic resonance imaging (fMRI; lasting under an hour), and receive a brief administration of transcranial magnetic stimulation (TMS; lasting under a minute) on the 2nd and 3rd in-person appointments

· Total time commitment is approximately 11 to 16 hours

$25/hour; round-trip transportation between NKI and the NYC area

.

For more information about this study, please call the Psychiatric NeuroCognition Laboratory at 845-398-5590, email   or visit  .

 

Healthy Dieters Needed!

i22-01630

 Candace M. Raio, Assistant Professor, Department of Psychiatry, NYU School of Medicine

NYU Langone Health is currently seeking healthy dieters to participate in a behavioral research study to understand how individuals make decisions about rewards and self control. The study entails two study sessions. During the first session, you will complete self-report surveys and cognitive tasks; during the second session you will complete a reward-based choice task that involves decisions about money and snack foods.

· Healthy females and males on a 

· Age 18-64 years old

· Able to speak, read and write fluently in English

· Willing and able to follow study procedures and provide informed consent

· No past or present neurological, psychiatric or metabolic disorders or medications

· Must not have diabetes, food allergies, a heart condition or high blood pressure.

· Must not be using beta-blockers or corticosteriods

 NYU Department of Psychiatry

                                  One Park Avenue

                                  8th floor, office 309

                                  New York, NY 10016

up to $75 across both study sessions

. If you qualify, you will receive an email in 1-3

For more information, please email

RUNNING STRATEGIES STUDY

IRB-FY2019-2931

Dr. Emily Balcetis 

 Jason Kemp

The study is designed to learn more about various running strategies and how to improve running performance.

.

Based on your current exercise routine, you may qualify for participation. If you qualify, in 1-3 days an invitation will be emailed

to you to set up an appointment time. If you are not currently living within the United States, you will automatically not qualify.

On the day of the appointment, you will complete 2 running challenges aimed to improve one's running performance. PLEASE

NOTE, we are looking for participants who run as a consistent part of their weekly routine.  

There will be 2 running periods, the first will be a 30-minute run, the second will be an 8-minute run. 

      The John V. Lindsay East River Park Track 

                                 1234 E 6th St

                                 New York, NY 10009


                                The Armory Track

                                216 Fort Washington Ave

                                New York, NY 10032

 

$15 Amazon Gift Card

Participation in this study will take approximately 1 - 11/2 hours: 38 minutes to complete the running tests,

and 30 minutes to rest and learn select running strategies. 


Complete the qualifying survey to see if you qualify to participate in this study.  

:

Jason Kemp ([email protected]

Understanding Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder

i21-00454

Right handed adults, ages 18-50, who may have generalized anxiety disorder.


The purpose of this study is to understand how Mindfulness-Based Stress Reduction (MBSR) compared to a Stress

Education (SE) class works for patients with generalized anxiety disorder (GAD). Specifically, we want to understand

brain changes ("neural mechanisms") that contribute to reduction in GAD symptoms with MBSR treatment compares

to Stress Education, and to examine the degree to which treatment response may be explained by sex differences

in these neural mechanisms. Participants are randomized into two 8-week interventions: (1) MBSR or 2) Stress

Education. Participants randomized to the MBSR intervention will partake in an 8-week Mindfulness-Based Stress

Reduction (MBSR) program, taught and facilitated by a trained instructor. The classes instruct participants in the theory

theory and practice of several forms of mindfulness meditation: a body scan, breathing awareness, and mindfulness

stretching exercises designed to bring aware of the body and current experience of movement. Participants randomized

to the SE intervention will partake in an 8-week Stress Education (SE) program. The course is information based and

provided psychoeducation on stress, stress responses, and understanding the role of genes and environment in health.

· Your information will remain private.

· You will receive compensation for your time.

To learn more about the study and see if it is something you would be interested in and a good fit for, please fill out

the following survey:  .

Research Coordinator, Leo Almada-Makebish; .

Interested in participating in OCD Research?

We are looking for individuals with Obsessive-Compulsive Disorder (OCD) for our study at NYU Langone Health! The purpose of this study is to look at clinical symptoms, behavior, and brain function in the disorder.

• Be 18-55 years old

• Be medically healthy

What would you have to do?

• Some questionnaires about your health and emotions

• Some computer tasks while having your brain activity measured with functional magnetic resonance imaging (fMRI)

Total participation time is 6 to 12 hours over 1 to 3 visits (some may be done remotely) and pays at a rate of $25 per hour.

If you want us to contact you to tell you more about the study, please fill out our study interest form: https://redcap.link/PNCLab

For more information, call the Psychiatric neurocognition Laboratory at 646-754-4471, email us at [email protected] or visit us at psychneurocoglab.com .

Please do not disclose any personal or sensitive information via email.

Healthy Dieters Needed for Decision-Making Study

Study Number: i18-01945

Investigator: Candace M. Raio, PhD, Department of Psychiatry, NYU School of Medicine

Study Description: NYU Langone Health is currently seeking healthy adults to participate in a functional Magnetic Resonance Imaging (fMRI) research study to investigate how emotions influence the way in which the brain makes decisions about rewards. The study entails a single session, lasting approximately 2 hours total (1 hour in the MRI scanner, plus 1 hour outside the scanner). Outside of the scanner, you will complete self-report surveys and may undergo a mild stressor as well as provide saliva samples to assess stress hormones. In the scanner, you will rate and make choices about different food rewards.  

Specific Requirements: · Healthy females and males between 18-64 yrs old on a diet to lose or maintain weight.
· Must not have metal in or on body that cannot be removed. · Must not be pregnant. · No history of and/or medication for any neurological, psychiatric or metabolic disorders. · Must not have diabetes, food allergies, a heart condition or high blood pressure. · Must not be taking beta-blockers or corticosteroids. Study Location: NYU's Center for Brain Imaging 4-6 Washington Place, Rm 157A New York, NY 10003

Compensation: Up to $55


 If interested, please complete our qualifying survey here:  https://openredcap.nyumc.org/apps/redcap/surveys/?s=3LDJDPMYPNFACKEF If you qualify, you will receive an email in 1-3 days about future availability for an experimental session.

Contact Information: For more information, please email: [email protected]

Are you a medically healthy adult?

We are looking for healthy control subjects for a study looking at the neurobiology of psychiatric disorders at NYU Langone Health. You must be between the ages of 18 and 55 and in good physical and mental health. If eligible, we will ask you to come in for 1-3 separate appointments (some may be done remotely) for a total time commitment of approximately 6 to 12 hours. You will be reimbursed for your participation at a rate of 25 dollars per hour.

During this research study you will be asked to complete some computer tasks while having your brain activity measured using functional magnetic resonance imaging (fMRI). We will also ask you about your health and to fill out some questionnaires about your emotions. If you want us to contact you to tell you more about the study, please fill out our study interest form: https://redcap.link/PNCLab

For more information, call the Psychiatric NeuroCognition Laboratory at 646-754-4471, email us at [email protected] or visit us at psychneurocoglab.com. Please do not disclose any personal or sensitive information via email.

Rockefeller University

Research at the rockefeller university.

Research at the Rockefeller University

Research Areas and Laboratories

Clinical research and the rockefeller university hospital.

An exchange of ideas between fundamental research and clinical investigation is at the core of Rockefeller’s mission. The Rockefeller University Hospital serves as a crucial link between bench and bedside.

Clinical Research Studies  

Research studies conducted at The Rockefeller University Hospital offer volunteers the opportunity to advance research knowledge and medical progress.

  • View research studies

Collaborations and Partnerships

Tri-institutional and external collaborations.

Rockefeller scientists move discoveries beyond the laboratory through active collaborations in New York City and beyond.

  • View all collaborations

Interdisciplinary Centers

Rockefeller’s interdisciplinary centers unite researchers in disparate labs around specific clinical goals, fostering collaboration.

  • View all interdisciplinary centers

Technology Transfer

The Office of Technology Transfer helps university personnel shepherd inventions, materials, and technologies into useful commercial products.

  • Visit the Office of Technology Transfer

Research Support

Resource centers.

More than a dozen shared resource centers provide scientists with access to advanced tools and technology.

  • View all resource centers

Research and Grant Assistance  

The Office of Sponsored Research and Program Development assists investigators with securing and managing sponsored research awards.

  • Visit SR-PD

Markus Library

The university’s library supports the community with technology, innovation, and collaboration in the field of science information and communication.

  • Visit the Markus Library

Agata Smogorzewska, M.D., Ph.D.

Agata Smogorzewska, M.D., Ph.D.

Associate professor.

Jean-Laurent Casanova

Jean-Laurent Casanova, M.D., Ph.D.

The rockefeller university press  .

For more than 100 years, the Rockefeller University Press has provided scientists and the public with peer-reviewed results of groundbreaking research.

  • Visit the Rockefeller University Press

Recent Scientific Publications

  • Search all publications

Recent Awards and Honors

2024 national academy of sciences, 2022 national academy of medicine, 2022 the royal society.

  • 2024 Highlights in Faculty Awards

Leslie B. Vosshall honored with the Dickson Prize in Medicine

Light-weight microscope captures large-scale brain activity of mice on the move, surprising origins for a rare cancer.

  • View all news

Upcoming Events

Human reference genomes for high-precision omics analyses, introduction to r.

  • View all upcoming events

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ACTIVE MARKET RESEARCH STUDIES IN NEW YORK CITY, NEW YORK

Participate in market research in NEW YORK CITY! Our platform updates daily all the active focus groups, app installs, clinical trials, online surveys, product testing and other studies. Apply for free and never miss a chance to earn money when voicing your opinion.

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About Integrated Medical Professionals (IMP) Research

Integrated medical professionals (imp) research is a multi-specialty medical clinical trial research site located in midtown manhattan. assisting some of the world's finest pharmaceutical companies uncover new treatments, we help patients better manage their healthcare. conducting clinical trials and research studies for a most medical specialties; including urology, dermatology, gastroenterology, endocrinology/diabetes, sexual dysfunction and more. we urge you to explore our website to learn about our current research study opportunities and our impressive medical staff responsible for overseeing them..

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UTI Research

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Click here for a list of our current studies.

research studies new york

  • Diversity in Clinical Research
  • Clinical Research for Older Populations
  • Clinical Research for Compensation
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  • What Is A Clinical Trial?

Healthy Paid Clinical Trials in New York

Match to clinical trials, browse by healthy clinical trials by city.

This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Policylab.us does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program

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Explore Paid Clinical Trials and Research Studies in New York City | Clinical Research

research studies new york

Are you interested in contributing to medical advancements and receiving compensation? New York City offers a wide range of paid clinical trials and research studies for individuals willing to participate. These studies not only help researchers further their knowledge, but they also provide an opportunity for participants to take an active role in developing new treatments and therapies.

Clinical trials enable participants to receive medical attention while also benefiting from paid compensation. New York City is home to various prestigious institutions conducting cutting-edge research studies in different therapeutic areas. From generalized anxiety disorder to obsessive-compulsive disorder, these studies provide valuable information and insights into a wide range of medical conditions.

Key Takeaways

  • NYC offers a wide range of paid clinical trials and research studies
  • Participation enables individuals to contribute to medical advancements
  • Compensation is available for participation in various prestigious institutions
  • Various therapeutic areas and medical conditions are covered
  • Clinical trials provide valuable insights into medical research

NYC Paid Research Studies: An Opportunity to Make a Difference

Are you interested in taking part in paid research studies and clinical trials in New York City? Look no further! There are numerous opportunities near you actively recruiting volunteers for paid studies.

Participating in these studies not only allows you to contribute to medical advancements and potentially improve treatments for various conditions, but it also provides compensation for your time and effort. These studies can range from behavioral research to clinical trials, with a focus on various therapeutic areas.

If you are interested in taking part, be sure to take a look at our upcoming sections for more information on eligibility criteria, compensation, and how to get involved. You can also visit research institutions like NYU Langone and the Nathan Kline Institute.

Types of Research Studies and Clinical Trials in NYC

Are you interested in participating in a research study or clinical trial? New York City is home to many renowned institutions conducting studies across various fields. These studies can range from focus groups and behavioral research at NYU and Columbia University Medical Center to clinical studies targeting conditions such as generalized anxiety disorder and obsessive-compulsive disorder.

Many studies use randomized methods to ensure accuracy and minimize bias. Some also use placebo-controlled groups to compare the effects of the treatment being studied to those of a placebo.

If you’re looking to get involved in a research study, it’s important to note that many studies actively recruit volunteers in the area. Institutions like NYU and Columbia are constantly looking for eligible participants, so keep an eye out for opportunities and consider contacting research teams to learn more.

Examples of Studies:

  • An NYU study on the effects of transcranial magnetic stimulation on individuals with obsessive-compulsive disorder
  • A Columbia University Medical Center study on the effects of a new treatment for generalized anxiety disorder
  • A randomized clinical trial at NYU Langone Health to evaluate the effectiveness of a new treatment for major depressive disorder
  • A Nathan Kline Institute study on learning and memory in adults
  • An observational study at the School of Medicine to better understand the effects of a first-line treatment for obsessive-compulsive disorder

Whether you’re eligible for a research study or clinical trial, participation can provide a unique opportunity to contribute to medical advancements while potentially receiving compensation for your time and efforts.

Purpose and Process of Participating in Research Studies

Participating in research studies can serve several purposes, including evaluating new treatments and therapies. Research teams evaluate the effectiveness of new treatments and compare them with existing treatments to determine their potential application.

Interested individuals can participate in research studies by completing questionnaires or visiting study sites. Some studies may involve being part of a research team in the Department of Psychiatry where participants can contribute to research on various therapeutic areas.

Paid trials and research studies are available across various therapeutic areas, including generalized anxiety disorder and obsessive-compulsive disorder. These studies use placebo-controlled designs to determine the safety and effectiveness of new treatments.

Volunteers who participate in these studies receive compensation for their time and contribution. The research team evaluate volunteers’ eligibility and after accepting their participation, volunteers receive payment for their time.

Eligibility Criteria and Compensation for Research Study Participants

Participating in a research study or clinical trial can be a great opportunity to help advance medical research while also receiving compensation for your time and effort. Eligibility criteria for these studies can vary widely depending on the specific study’s goals and requirements.

At NYU Langone Medical Center, for example, ongoing studies are actively looking for participants who are eligible for research studies related to anxiety, depression, and other conditions. Participants in these studies will receive compensation for their participation, and the goal is to better understand these disorders and evaluate potential new treatments.

In general, to be eligible for a research study or clinical trial, individuals must meet certain criteria, such as age, gender, medical history, and specific symptoms. The study’s purpose and requirements will determine who is eligible for participation.

If you are interested in participating in a research study at NYU Langone Health or another institution, you can contact the relevant study team or laboratory to learn more about the study’s eligibility criteria and compensation details. Remember that participation in these studies is entirely voluntary, and you can choose to withdraw at any time.

How to Get Involved in NYC Paid Research Studies

If you’re interested in participating in NYC paid research studies, there are numerous opportunities available. Many studies require the participation of volunteers, and you can get involved by calling the psychiatric neurocognition laboratory at 646-754-4471 or by visiting institutions like the Nathan Kline Institute or NYU Langone Health.

The purpose of this research study involves advancing medical research, and you may receive compensation for your participation. Take advantage of these opportunities to contribute to the medical field while also benefiting from potential compensation.

It’s important to note that each study involves its own specific requirements and process of participation. Research study at NYU Langone, for instance, allows volunteers to take part in studies tailored to various medical research fields. Participants will receive the opportunity to help evaluate new treatments and therapies, complete questionnaires, and visit study sites.

When considering participation in any research study, it’s important to carefully review the eligibility criteria and potential compensation. Don’t hesitate to call the relevant research laboratory or institution to receive more information. The potential benefits of your participation could extend far beyond simply receiving compensation for your time and travel.

Advancements in Medical Research and Opportunities for Volunteers

For eligible participants interested in participating, New York University’s School of Medicine is conducting an observational study to find individuals with obsessive-compulsive disorder. The study, led by the Psychiatric Neurocognition Laboratory, aims to understand brain function in the disorder. The total participation time is 8-week, and compensated for their time. Subjects will receive health advice or treatment.

If you would like to participate in this study or learn more about other trials related to learning and memory, you may contact the Psychiatric Neurocognition Laboratory at 646-754-4471, or email [email protected] or visit their website. The goal of this study is to determine the effects of transcranial magnetic stimulation and evaluate its effectiveness as a first-line treatment. Individuals with major depressive disorder may also be asked to participate in a treatment study that takes three days and only minutes to complete. The study is currently being conducted in Buffalo and the Bronx and has been reviewed and approved by health professionals. Interested participants might be eligible for compensation for their participation time and travel.

Eligibility criteria vary for each study, and subjects will be asked to complete a questionnaire to determine if they meet the inclusion and exclusion criteria. The secondary objectives of the study involve evaluating the effects of transcranial magnetic stimulation on brain function in subjects with major depressive disorder.

Participation in this study, and others like it, could help advance medical research and ultimately lead to the development of better treatments for obsessive-compulsive disorder and other conditions. Contact the Psychiatric Neurocognition Laboratory to take the place in these important trials and help further scientific knowledge.

research studies new york

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Velocity Clinical Research

Binghamton, New York

Velocity clinical research, binghamton.

Velocity’s research site in Binghamton partners with United Health Services (UHS) to conduct clinical trials for a broad range of investigational treatments. Research studies at this site explore vaccines and medicines developed to treat migraines, diabetes, acne, depression, high cholesterol, and other conditions. All trials conducted at the site are performed in accordance with ICH and FDA guidelines, and in compliance with GCP. Acquired by Velocity in 2022, the Binghamton location conducted clinical trials for years, first with Regional Clinical Research, then as part of Meridian Clinical Research.

Through the partnership with UHS, the site is easily accessible to thousands of patients, including those established with the practice. Our Binghamton team is committed to being a resource for study participants, to providing the highest quality of patient care with compassion and kindness, and to advancing medicine through research.

Velocity Clinical Research, Binghamton 1130 Upper Front St., Binghamton, NY 13905

Phone: (607) 800-5777

Find a Clinical Trial in Binghamton Use the dropdown to browse current studies in Binghamton.

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About Velocity Clinical Research

155,000+ people have a joined a study at velocity.

Many people enjoy the study experience and have joined several clinical trials at Velocity.

Velocity has decades of research experience

With sites that were established as long ago as 1986, Velocity has experts who have supported clinical trials for decades.

Velocity studies are led by healthcare professionals

All clinical trials conducted at Velocity are overseen by the U.S. Food and Drug Administration (FDA).

Our experienced research team in Binghamton

Every clinical trial is overseen by a Principal Investigator – a physician who is responsible for the rights, safety and welfare of the study participants. All physicians at Velocity are board certified in their specialty area(s) and all research staff is trained in clinical research regulations, including GCP and HIPAA. Our clinical research team in Binghamton is dedicated to conducting quality research in a professional and caring environment.

research studies new york

Frank Eder, MD

Principal Investigator Frank Eder, MD is a lead physician for United Health Services who has been in practice for more than 20 years. Board certified in Family Medicine, Dr. Eder received his medical degree from SUNY Downstate Medical Center in Brooklyn, NY and completed a family medicine residency at United Health Services Hosptials in Johnson City, NY.

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How Do Our Memories Last a Lifetime? New Study Offers a Biological Explanation

Whether it’s a first-time visit to a zoo or when we learned to ride a bicycle, we have memories from our childhoods kept well into adult years. But what explains how these memories last nearly an entire lifetime? 

A new study in the journal Science Advances , conducted by a team of international researchers, has uncovered a biological explanation for long-term memories. It centers on the discovery of the role of a molecule, KIBRA, that serves as a “glue” to other molecules, thereby solidifying memory formation.

“Previous efforts to understand how molecules store long-term memory focused on the individual actions of single molecules,” explains André Fenton, a professor of neural science at New York University and one of the study’s principal investigators. “Our study shows how they work together to ensure perpetual memory storage.”

“A firmer understanding of how we keep our memories will help guide efforts to illuminate and address memory-related afflictions in the future,” adds Todd Sacktor, a professor at SUNY Downstate Health Sciences University and one of the study’s principal investigators.

Discovery of a "glue" molecule's purpose affirms a concept introduced Nobel Laureate Francis Crick to explain the brain’s role in memory storage.

It’s been long-established that neurons store information in memory as the pattern of strong synapses and weak synapses, which determines the connectivity and function of neural networks. However, the molecules in synapses are unstable, continually moving around in the neurons, and wearing out and being replaced in hours to days, thereby raising the question: How, then, can memories be stable for years to decades?  

In a study using laboratory mice, the scientists focused on the role of KIBRA, or kidney and brain expressed protein, the human genetic variants of which are associated with both good and poor memory. They focused on KIBRA’s interactions with other molecules crucial to memory formation—in this case, protein kinase Mzeta (PKMzeta). This enzyme is the most crucial molecule for strengthening normal mammalian synapses that is known, but it degrades after a few days.

Their experiments reveal that KIBRA is the “missing link” in long-term memories, serving as a “persistent synaptic tag,” or glue, that sticks to strong synapses and to PKMzeta while also avoiding weak synapses.

“During memory formation the synapses involved in the formation are activated—and KIBRA is selectively positioned in these synapses,” explains Sacktor, a professor of physiology, pharmacology, anesthesiology, and neurology at SUNY Downstate. “PKMzeta then attaches to the KIBRA-synaptic-tag and keeps those synapses strong. This allows the synapses to stick to newly made KIBRA, attracting more newly made PKMzeta.”

More specifically, their experiments in the Science Advances paper show that breaking the KIBRA-PKMzeta bond erases old memory. Previous work had shown that randomly increasing PKMzeta in the brain enhances weak or faded memories, which was mysterious because it should have done the opposite by acting at random locations, but the persistent synaptic tagging by KIBRA explains why the additional PKMzeta was memory enhancing, by only acting at the KIBRA tagged sites. 

Memories are stored by the interaction of two proteins: a structural protein, KIBRA (green), that acts as a persistent synaptic tag, and a synapse-strengthening enzyme, protein kinase Mzeta (red). Drugs that disrupt the memory-perpetuating interaction (other colors) erase pre-established long-term and remote memories. Credit: Changchi Hsieh, Ph.D.

“The persistent synaptic tagging mechanism for the first time explains these results that are clinically relevant to neurological and psychiatric disorders of memory,” observes Fenton, who is also on the faculty at NYU Langone Medical Center’s Neuroscience Institute. 

The paper’s authors note that the research affirms a concept introduced in 1984 by Francis Crick. Sacktor and Fenton point out that his proposed hypothesis to explain the brain’s role in memory storage despite constant cellular and molecular changes is a Theseus’s Ship mechanism—borrowed from a philosophical argument stemming from Greek mythology in which new planks replace old ones to maintain Theseus’s Ship for years.

“The persistent synaptic tagging mechanism we found is analogous to how new planks replace old planks to maintain Theseus’s Ship for generations, and allows memories to last for years even as the proteins maintaining the memory are replaced,” says Sacktor. “Francis Crick intuited this Theseus’s Ship mechanism, even predicting the role for a protein kinase. But it took 40 years to discover that the components are KIBRA and PKMzeta and to work out the mechanism of their interaction.”

The study also included researchers from Canada’s McGill University, Germany’s University Hospital of Münster, and University of Texas Medical School at Houston.

This work was supported by grants from the National Institutes of Health (R37 MH057068, R01 MH115304, R01 NS105472, R01 MH132204, R01 NS108190), the Natural Sciences and Engineering Research Council of Canada Discovery (203523), and the Garry and Sarah S. Sklar Fund.

About New York University Founded in 1831, NYU is one of the world’s foremost research universities (with more than $1 billion per year in research expenditures, it is ranked seventh among private research universities) and is a member of the selective Association of American Universities. NYU has degree-granting university campuses in New York, Abu Dhabi, and Shanghai; has 13 other global academic sites, including London, Paris, Florence, Tel Aviv, Buenos Aires, and Accra, and US sites in Washington, DC, Los Angeles, CA, and Tulsa, OK; and both sends more students to study abroad and educates more international students than any other U.S. college or university. Through its numerous schools and colleges, NYU is a leader in conducting research and providing education in the arts and sciences, law, medicine, business, dentistry, engineering, education, nursing, the cinematic and performing arts, music and studio arts, public service, social work, public health, and professional studies, among other areas.

About SUNY Downstate Health Sciences University Downstate Health Sciences University in Brooklyn is one of four academic health centers (AMCs) in the 64-campus State University of New York (SUNY) system and the only SUNY AMC in New York City dedicated to health education, research, and patient care for the borough’s 2.7 million residents. Its flagship hospital, University Hospital at Downstate (UHD), is a teaching hospital that benefits from the expertise of Downstate’s exceptional medical school and world-class research facilities. Beyond its clinical excellence, Downstate houses a range of esteemed educational institutions, including the College of Medicine, College of Nursing, School of Health Professions, School of Graduate Studies, and School of Public Health. Downstate fosters innovation through its multifaceted biotechnology initiatives, including the Biotechnology Incubator and BioBAT, which support both early-stage and more mature biotech companies. Downstate’s research enterprise drives innovation and discovery across a wide array of disciplines. Our investigators are making discoveries that are changing the world and pushing the boundaries of what is possible in biomedicine and healthcare.

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Exercise may lower the als risk for men — but not women: new study.

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Moderate or vigorous exercise may lower the risk of ALS, a fatal disease, for men but not women, new research finds .

The study, published Wednesday in Neurology , the medical journal of the  American Academy of Neurology , followed 373,696 Norwegian people for about 27 years.

Participants recorded their physical activity, ranging from sedentary to moderate to intense. During the follow-up period, 504 people developed ALS.

ALS Diagnosis. Medical Concept.

Adjusting for lifestyle factors that can affect the risk of ALS, like smoking and body weight, researchers found that male participants who reported moderate levels of physical activity had a 29% lower risk of ALS while high levels of physical activity meant a 41% lower risk.

The study only found an association between physical activity and the risk of ALS in male, not female participants.

EWFCE8 Confident man and woman doing stretching exercise in crossfit gym

Researchers also analyzed participants’ resting heart rates, an indicator of overall fitness, finding that those with the lowest rates had a 32% reduced risk of ALS compared to participants with higher rates.

Study author Dr. Anders Myhre Vaage, of Akershus University Hospital in Norway, notes that the diagnosis of ALS in high-profile athletes has spurred the thinking that strenuous physical activity is an environmental risk factor that leads to the development and early onset of the disease.

One study found that NFL players are four times more likely to develop and die from ALS than the general adult male population.

Research has also shown that ALS risk genes are activated by exercise, adding to the growing debate about the relationship between physical activity and ALS.

“There have been conflicting findings on levels of physical activity, fitness and ALS risk,” Myhre Vaage said. “Our study found that for men, living a more active lifestyle could be linked to a reduced risk of ALS more than 30 years later.”

What is ALS?

MNAW7K May 14, 2018 - Philadelphia, PA, USA:  An elderly man breathes with the assistance of a ventilator.

ALS, also referred to as Lou Gehrig’s disease, for the Hall of Fame baseball player who died of it in 1941, is a progressive neurodegenerative disease. With ALS, the nerve cells that control muscle function deteriorate, and patients gradually become unable to walk, move, eat, speak and breathe, leading to partial or total paralysis and death.

There is no known cure for ALS — the average life expectancy after diagnosis is two to five years.

research studies new york

Myhre Vaage hopes the study’s findings lead to more research on ALS risk factors.

“Our findings show that, for men, not only do moderate to high levels of physical activity and fitness not increase the risk of ALS, but that they may be protective against the disease,” he said. “Future studies of the connection between ALS and exercise are needed to consider sex differences and higher or professional athlete physical activity levels.”

Other research suggests that the type of physical activity is an important factor in mitigating ALS risk. For example, one study proposed that golfing and gardening put men at three times greater risk of developing ALS.

That study found that golfers and gardeners are especially prone because of frequent exposure to pesticides, which  prior research has tied  to the disease’s development.

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Famous people who have been diagnosed with ALS

Steve McMichael, pictured when playing for the Bears, was diagnosed with ALS in 2021.

According to the ALS Association , someone dies from ALS and someone is diagnosed with it every 90 minutes — and celebrities are not immune to its punishing effects.

Footballer Dwight Clark and physicist, cosmologist and author Stephen Hawking have lost their battles with the disease, while singer Roberta Flack , sportswriter Sarah Langs  and former Chicago Bears football player Steve McMichael are still fighting.

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Guest Essay

What Happened to Stanford Spells Trouble for the Election

An illustration showing the repeated words “the steal” in red on a black background.

By Renée DiResta

Ms. DiResta is the former research director of the Stanford Internet Observatory, a unit of Stanford University that studies abuse of online platforms.

In 2020 the Stanford Internet Observatory, where I was until recently the research director, helped lead a project that studied election rumors and disinformation. As part of that work, we frequently encountered conspiratorial thinking from Americans who had been told the 2020 presidential election was going to be stolen.

The way theories of “the steal” went viral was eerily routine . First, an image or video, such as a photo of a suitcase near a polling place, was posted as evidence of wrongdoing. The poster would tweet the purported evidence, tagging partisan influencers or media accounts with large followings. Those accounts would promote the rumor, often claiming, “Big if true!” Others would join, and the algorithms would push it out to potentially millions more. Partisan media would follow.

If the rumor was found to be false — and it usually was — corrections were rarely made and even then, little noticed. The belief that “the steal” was real led directly to the events of Jan. 6, 2021.

Within a couple of years, the same online rumor mill turned its attention to us — the very researchers who documented it. This spells trouble for the 2024 election.

For us, it started with claims that our work was a plot to censor the right. The first came from a blog related to the Foundation for Freedom Online, the project of a man who said he “ran cyber” at the State Department. This person, an alt-right YouTube personality who’d gone by the handle Frame Game, had been employed by the State Department for just a couple of months .

Using his brief affiliation as a marker of authority, he wrote blog posts styled as research reports contending that our project, the Election Integrity Partnership, had pushed social media networks to censor 22 million tweets. He had no firsthand evidence of any censorship, however: his number was based on a simple tally of viral election rumors that we’d counted and published in a report after the election was over. Right-wing media outlets and influencers nonetheless called it evidence of a plot to steal the election, and their followers followed suit.

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  1. New York Paid Clinical Trials & Research Studies Near You (Updated 6/24)

    397. ›. New York is currently home to 4763 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a ...

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    The purpose of this study is to see if magnesium can improve postoperative pain in patients who have urologic surgery. Magnesium Sulfate is a medication ... View Details. Search NYU Langone's database of clinical trials and research studies examining new treatments and diagnostic tools for medical conditions.

  3. New York, NY Paid Clinical Trials & Research Studies Near You (Updated

    278. ›. There are currently 3331 clinical trials in New York, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including Memorial Sloan Kettering Cancer Center, Columbia University Medical Center, Icahn School of Medicine at Mount Sinai and Columbia University.

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    Study Location: NYU Department of Psychiatry. One Park Avenue. 8th floor, office 309. New York, NY 10016. Compensation: up to $75 across both study sessions. If interested, please complete our qualifying survey here. If you qualify, you will receive an email in 1-3. days about future availability for an experimental session. Contact Information:

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    Clinical trials help us develop new medicines and medical treatments. At Mount Sinai, we try to improve how we prevent, diagnose, and treat conditions and diseases. Once an approach has shown promise in a laboratory, we need to test it with volunteers. All clinical trials are approved by governmental and health system groups.

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    At NYU Langone Health, our clinical research mission is to support, train, inspire, supervise, and facilitate a network of health practitioners who conduct research to improve health and manage disease. We have more than 500 highly specialized research faculty members representing more than 50 countries. Among them, they published 6,644 ...

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    Research Alliance for New York City Schools: Rudin Center for Transportation Policy & Management: Salomon Center for the Study of Financial Institutions: Sloan-Swartz Center for Theoretical Visual Neuroscience: Taub Center for Israel Studies: The Center for Practice and Research at the Intersection of Information, Society, and Methodology (PRIISM)

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    For more than 100 years, the Rockefeller University Press has provided scientists and the public with peer-reviewed results of groundbreaking research. Visit the Rockefeller University Press. December 14, 2022. November 16, 2022. December 14, 2022. Search all publications. 2024 Highlights in Faculty Awards. View all news.

  12. New York Clinical Trials

    All clinical trials that recruit human participants have been reviewed and approved, and both non-paid and paid clinical research studies exist in New York. After the study is approved the research team sets out to recruit volunteers who would like to participate in a clinical trial. Usually, volunteers are compensated for their time and travel ...

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    The Mount Sinai Health System's work with Alzheimer's disease spans a multi-site network of clinics, hospitals, and practices. We treat more than 3,000 patients every year, and our translational research programs have been awarded in excess of $200 million from NIH and other agencies. The Loeb Center's mission is to develop state-of-the-art ...

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    Our Clinical Trials. Research studies are currently under way to develop and assess new medications, novel forms of psychotherapy, and innovative neuroimaging methods. We have conducted and continue to direct clinical trials for disorders such as: Anxiety. Attention deficit hyperactivity disorder (ADHD) Autism spectrum disorder. Bipolar disorder.

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    Contact Us. Alzheimer's Disease Research Center 145 East 32nd Street 2nd Floor New York, NY 10016. For general information, appointments, and study information, please call 212-263-8088. For clinical trials information, please call 212-263-0771. For information on our Brain Donation Program, please call 212-263-6262.

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  20. New York Healthy Paid Clinical Trials & Research Studies Near You

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    Meet Our Binghamton Research Team. Velocity Clinical Research, Binghamton. 1130 Upper Front St., Binghamton, NY 13905. Phone: (607) 800-5777. Find a Clinical Trial in Binghamton. Use the dropdown to browse current studies in Binghamton. (Required) Follow Velocity on Facebook for company updates and more.

  23. How Do Our Memories Last a Lifetime? New Study Offers a ...

    About New York University Founded in 1831, NYU is one of the world's foremost research universities (with more than $1 billion per year in research expenditures, it is ranked seventh among private research universities) and is a member of the selective Association of American Universities.

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    Our CTN research studies are funded by a parent grant, NIDA CTN: Greater New York Node; 5UG1DA013035. Several NYU Langone investigators are a part of the CTN's Greater New York Node, which also consists of scientists from other area institutions. ... Genetics Study; CTN-0051-A-1 Greater New York Node investigators: Mary Jeanne Kreek, MD ...

  25. Exercise could lower ALS risk for men

    Moderate or vigorous exercise may lower the risk of ALS, a fatal disease, for men but not women, new research finds. The study, published Wednesday in Neurology, the medical journal of the ...

  26. Opinion

    Ms. DiResta is the former research director of the Stanford Internet Observatory, a unit of Stanford University that studies abuse of online platforms. In 2020 the Stanford Internet Observatory ...