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Sample student biology research proposal (P. Pazos & P. Hirsch 2008)

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1.4: Research Proposals

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Learning Objectives

• Perform biodiversity research through making and translating your observations of the natural world into research questions, hypotheses, and experimental design that are grounded in scientific literature.
• Communicate the research process to your peers in a clear, effective, and engaging manner.

Written Proposal

Writing about research is a primary method scientists use to communicate their work. Thus, this course will involve developing a written research proposal. We will use several drafts to refine the research proposal. The first draft can utilize the template available in Appendix 6. Subsequent drafts should become more refined and start to take the format of a scientific paper. The proposal should include an introductory section providing background on the topic of interest, drawing from several primary research articles. This section also develops the argument for why the research question is worth studying. The research question and hypothesis should also be included in the introduction.

The second section should include the proposed methodology. Describe how the hypothesis will be tested. It should outline the experiments and what will be needed to perform them. Ideas can be supported by referring to previously published research. The third section will address anticipated results. Consider the expected findings and the implications of those findings for the original research question and hypothesis. Consider what it would mean if the results turned out a different way. Finally, be sure to include both in-text citations and a full reference list at the end. The proposal should have good narrative flow and be proofread for proper spelling and grammar. See the rubric in the Appendix 3 for evaluation guidelines.

Oral Presentation

Scientists also frequently share their research findings via presentations, such as at meetings with other scientists. Developing an oral presentation of the research proposal provides an opportunity to practice communicating science to our peers. The presentation should be ~10 minutes and delivered via a slideshow. The presentation should include the same content as the written portion, but the distinction here the audience will be engaged in a different way. The best presentations tell a good story, so think about how to translate the proposal into a story – typically start with background information so the audience members have some understanding of the context. Then use the background information strategically to build up to the identified research gap and the corresponding research question. The question then leads naturally into the hypothesis or hypotheses to be tested. The final part of the presentation will be the experimental plan – how will the hypothesis be tested? Try to envision all possible outcomes from the experiment and how that will support or refute the hypothesis and inform on the interpretation of the results.

There will be opportunities for questions from peers at the end. It is important to try to ask questions at the end of presentations in order to practice giving this kind of feedback. This is a very common way in which scientists provide feedback to each other on their work. Attending departmental seminars or conferences will enable witnessing this first hand. See the rubric in the Appendix 3 for evaluation guidelines.

Proposal Workshop I

Proposing research ideas is a key element of working in the biodiversity science field. Thus this first workshop will be focused on sharing and expanding upon initial ideas for a research proposal. It will take a lab meeting format with a round table discussion where each student has the opportunity to share their research proposal ideas. Peers will then ask follow-up questions to help support idea development. Incidentally, this also serves as an opportunity to practice communicating science to peers. It takes practice to clearly articulate ideas. Following the workshop, begin exploring some literature related to the topic of interest and start putting ideas down on paper – they will not be polished yet, but it will help to develop the initial draft of the research proposal. See the Appendix 6 for a proposal first draft template.

Proposal Workshop II

This workshop will continue to develop the research question, hypothesis, and experimental design. We will discuss developing ideas in pairs with both the course instructor and classmates. We will work to develop ideas into excellent proposal material by digging into the following questions.

Research Question

• What is your research question?
• Is your question clearly stated and focused? If not, how might you tailor it?
• Why are you interested in this question? What makes you curious about it? What have you learned from previous studies that lead you to want to ask this question?

Hypotheses/predictions

• What are your hypotheses/predictions?
• Are they stated clearly? If not, what needs to be adjusted?
• Are they aligned with the question you are asking?
• Why are you interested in this hypothesis?

Experimental Plan

• What is your experimental plan?
• Does the design fit with your hypothesis?
• Are there things that still need to be considered? If so, what are they?

Proposal Workshop III

This workshop is an opportunity to polish. Use this time to solicit final feedback from peers, test out design ideas for the final presentation, or practice delivering the presentation in front of an audience.

Science & Quantitative Reasoning Education

Yale undergraduate research, how to write a proposal.

The abstract should summarize your proposal. Include one sentence to introduce the problem you are investigating, why this problem is significant, the hypothesis to be tested, a brief summary of experiments that you wish to conduct and a single concluding sentence. (250 word limit)

Introduction

The introduction discusses the background and significance of the problem you are investigating. Lead the reader from the general to the specific. For example, if you want to write about the role that Brca1 mutations play in breast cancer pathogenesis, talk first about the significance of breast cancer as a disease in the US/world population, then about familial breast cancer as a small subset of breast cancers in general, then about discovery of Brca1 mutations in familial breast cancer, then Brca1’s normal functions in DNA repair, then about how Brca1 mutations result in damaged DNA and onset of familial breast cancer, etc. Definitely include figures with properly labeled text boxes (designated as Figure 1, Figure 2, etc) here to better illustrate your points and help your reader wade through unfamiliar science. (3 pages max)

Formulate a hypothesis that will be tested in your grant proposal. Remember, you are doing hypothesis-driven research so there should be a hypothesis to be tested! The hypothesis should be focused, concise and flow logically from the introduction. For example, your hypothesis could be “I hypothesize that overexpressing wild type Brca1 in Brca1 null tumor cells will prevent metastatic spread in a mouse xenograph model.” Based on your hypothesis, your Specific Aims section should be geared to support it. The hypothesis is stated in one sentence in the proposal. 

Specific Aims (listed as Specific Aim 1, Specific Aim 2)

This is where you will want to work with your mentor to craft the experimental portion of your proposal. Propose two original specific aims to test your hypothesis. Don’t propose more than two aims-you will NOT have enough time to do more. In the example presented, Specific Aim 1 might be “To determine the oncogenic potential of Brca1 null cell lines expressing wild type Brca1 cDNA”. Specific aim 2 might be “To determine the metastatic potential of Brca1 null cells that express WT Brca1”. You do not have to go into extensive technical details, just enough for the reader to understand what you propose to do. The best aims yield mechanistic insights-that is, experiments proposed address some mechanisms of biology. A less desirable aim proposes correlative experiments that does not address mechanistically how BRCA1 mutations generate cancer. It is also very important that the two aims are related but NOT interdependent. What this means is that if Aim 1 doesn’t work, Aim 2 is not automatically dead. For example, say you propose in Aim 1 to generate a BRCA1 knockout mouse model, and in Aim 2 you will take tissues from this mouse to do experiments. If knocking out BRCA1 results in early embryonic death, you will never get a mouse that yields tissues for Aim 2. You can include some of your mentor’s data here as “Preliminary data”. Remember to carefully cite all your sources. (4 pages max; 2 pages per Aim)

Potential pitfalls and alternative strategies

This is a very important part of any proposal. This is where you want to discuss the experiments you propose in Aims 1 and 2. Remember, no experiment is perfect. Are there any reasons why experiments you proposed might not work? Why? What will you do to resolve this? What are other possible strategies you might use if your experiments don’t work? If a reviewer spots these deficiencies and you don’t propose methods to correct them, your proposal will not get funded. You will want to work with your mentor to write this section. (1/2 page per Aim)

Cite all references, including unpublished data from your mentor. Last, First, (year), Title, Journal, volume, pages.

*8 page proposal limit (not including References), 1.5 spacing, 12pt Times New Roman font

• View an example of a research proposal submitted for the Yale College First-Year Summer Research Fellowship (PDF).  
• View an example of a research proposal submitted for the Yale College Dean’s Research Fellowship and the Rosenfeld Science Scholars Program (PDF) .

• Research Process

Writing a Scientific Research Project Proposal

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Table of Contents

The importance of a well-written research proposal cannot be underestimated. Your research really is only as good as your proposal. A poorly written, or poorly conceived research proposal will doom even an otherwise worthy project. On the other hand, a well-written, high-quality proposal will increase your chances for success.

In this article, we’ll outline the basics of writing an effective scientific research proposal, including the differences between research proposals, grants and cover letters. We’ll also touch on common mistakes made when submitting research proposals, as well as a simple example or template that you can follow.

What is a scientific research proposal?

The main purpose of a scientific research proposal is to convince your audience that your project is worthwhile, and that you have the expertise and wherewithal to complete it. The elements of an effective research proposal mirror those of the research process itself, which we’ll outline below. Essentially, the research proposal should include enough information for the reader to determine if your proposed study is worth pursuing.

It is not an uncommon misunderstanding to think that a research proposal and a cover letter are the same things. However, they are different. The main difference between a research proposal vs cover letter content is distinct. Whereas the research proposal summarizes the proposal for future research, the cover letter connects you to the research, and how you are the right person to complete the proposed research.

There is also sometimes confusion around a research proposal vs grant application. Whereas a research proposal is a statement of intent, related to answering a research question, a grant application is a specific request for funding to complete the research proposed. Of course, there are elements of overlap between the two documents; it’s the purpose of the document that defines one or the other.

Scientific Research Proposal Format

Although there is no one way to write a scientific research proposal, there are specific guidelines. A lot depends on which journal you’re submitting your research proposal to, so you may need to follow their scientific research proposal template.

In general, however, there are fairly universal sections to every scientific research proposal. These include:

• Title: Make sure the title of your proposal is descriptive and concise. Make it catch and informative at the same time, avoiding dry phrases like, “An investigation…” Your title should pique the interest of the reader.
• Abstract: This is a brief (300-500 words) summary that includes the research question, your rationale for the study, and any applicable hypothesis. You should also include a brief description of your methodology, including procedures, samples, instruments, etc.
• Introduction: The opening paragraph of your research proposal is, perhaps, the most important. Here you want to introduce the research problem in a creative way, and demonstrate your understanding of the need for the research. You want the reader to think that your proposed research is current, important and relevant.
• Background: Include a brief history of the topic and link it to a contemporary context to show its relevance for today. Identify key researchers and institutions also looking at the problem
• Literature Review: This is the section that may take the longest amount of time to assemble. Here you want to synthesize prior research, and place your proposed research into the larger picture of what’s been studied in the past. You want to show your reader that your work is original, and adds to the current knowledge.
• Research Design and Methodology: This section should be very clearly and logically written and organized. You are letting your reader know that you know what you are going to do, and how. The reader should feel confident that you have the skills and knowledge needed to get the project done.
• Preliminary Implications: Here you’ll be outlining how you anticipate your research will extend current knowledge in your field. You might also want to discuss how your findings will impact future research needs.
• Conclusion: This section reinforces the significance and importance of your proposed research, and summarizes the entire proposal.
• References/Citations: Of course, you need to include a full and accurate list of any and all sources you used to write your research proposal.

Common Mistakes in Writing a Scientific Research Project Proposal

Remember, the best research proposal can be rejected if it’s not well written or is ill-conceived. The most common mistakes made include:

• Not providing the proper context for your research question or the problem
• Failing to reference landmark/key studies
• Losing focus of the research question or problem
• Not accurately presenting contributions by other researchers and institutions
• Incompletely developing a persuasive argument for the research that is being proposed
• Misplaced attention on minor points and/or not enough detail on major issues
• Sloppy, low-quality writing without effective logic and flow
• Incorrect or lapses in references and citations, and/or references not in proper format
• The proposal is too long – or too short

Scientific Research Proposal Example

There are countless examples that you can find for successful research proposals. In addition, you can also find examples of unsuccessful research proposals. Search for successful research proposals in your field, and even for your target journal, to get a good idea on what specifically your audience may be looking for.

While there’s no one example that will show you everything you need to know, looking at a few will give you a good idea of what you need to include in your own research proposal. Talk, also, to colleagues in your field, especially if you are a student or a new researcher. We can often learn from the mistakes of others. The more prepared and knowledgeable you are prior to writing your research proposal, the more likely you are to succeed.

Language Editing Services

One of the top reasons scientific research proposals are rejected is due to poor logic and flow. Check out our Language Editing Services to ensure a great proposal , that’s clear and concise, and properly referenced. Check our video for more information, and get started today.

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Guidance for postgraduate applicants on writing a research proposal

Applicants should consult their prospective supervisor for advice both before writing, and for at least one round of feedback on their proposal.

The following points should be included when writing a research proposal:

• The topic that you propose to research: This should consist of a clear outline of the research you wish to do.
• The research context: relate your proposed research to other work in its field or related fields and indicate in what ways your research will differ.
• The contribution that your work will make to the field: this is your chance to show how you have arrived at your position and recognised the need for your research and what it is that makes it both new and important.
• The methodology and methods to be used in your study: this section should describe the methods and methodology you propose to employ as well as a justification for suitability of these methods in addressing your research topic.
• Fit with the Faculty and potential supervisor for PhD only: explain how your research fits in with the Faculty’s research interests and your potential supervisor.

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Department of Biological Sciences

Examples of Undergraduate Research Projects

Fall 2021 projects.

Student	Research Proposal
Whitney Brown	Characterizing the role of FOXP3 in ccRCC
Ziche Chen	Intereations between LANA and Super-enhancers
Anna Eberwein	Synaptic Dysfunction in the Drosophila Niemann Pick Type C Disease Model
Ivy Han	Investigating tension in epithelial wound healing
Cassidy Johnson	Elucidating Genes Involved in hoe-1-dependent UPRmt activation via a Forward Genetic Approach
Grace Lee	Microtubule dynamics regulates gap junction trafficking and placement in the motor circuit
Shuyang Lin	PGE2-G mediated P2Y6 signaling pathway
Robert McCarthy	Survivability of E. Coli Rho and H-NS mutants in various pH ranges.
Sharath Narayan	Identifying suppressor mutations in RNA polymerase to rescue replication-transcription conflicts
Dev Patel	Effects of CSK inhibition on Atrial Fibrillation
Jacque Pinon	The role of macrophages in obesity and metabolic disease
Brittany Polevikov	Defining the pathogenic cascade of P. aeruginosa in UTIs
Eddie Qian	Exosome treatment of ischemic kidney injury
Bennett Schneier	Copper Homeostasis in UPEC Bacteria
Elena Solopova	Correlation of White Matter MRI Hyperintensities with Expression of Lysyl Oxidase in Patients with Cerebral Amyloid Angiopathy
Carly Stewart	The Impact of Infection on Fecundity in Insects
Liraz Stilman	Telomeres and telomerase in yeast
Navya Thakkar	Rhythm and Grammar
Katherine Zhong	Negative Regulators of the Immune System

Previous Projects

Student	Research Proposal
Dhivyaa Anandan	Identifying mechanisms of tumor dormancy in the bone marrow
Patrick Bray	Stress effects of restricgted feeding in mice
Ivy Chen	The effect of domestication on cultural transmission of birdsong
Dara Craig	Camera trapping in Ecology
Jacob Edwards	Studies on GPBP within the extracellular matrix
Elise Erman	Development of assay to monitor error fre repair in non-homologous end joining
David Fei-Zhang	Characterization of BVES degrons
Jacob Gussert	Studying the nature of circadian rhythms in bacteria isolated from the natural environment
Alexis Gutierrez	Extracellular RNA
Alexander Kuraj	Examining the effect of photoperiod on the Trek-1 channel in serotonin neurons
Emily Layton	"Paternal Grandmother Age Affects the Strength of Wolbachia-Induced Cytoplasmic Incompatibility in Drosophila melanogaster."
Zelong Liu	Overexpression of xCT in noralized lung epithelial cells
Abby Perry	Effect of co-infection on the immune response of tribolium flour beetles
Carter Powers	The Effects of Temperature and Age on Immune Gene Expression in Anopheles gambiae
Anish Raman	Intersection of HSPG expression at the drosophilia neuromuscular junction
Saba Rehman	Characterization of neuregulin (NRG) trafficking
Sabeen Rehman	Positional cloning of a novel gene regulating craniofacial development
Zhan (Jack) Rong	The role of Rif1 in controlling DNA damage and structure during replication
Faith Rovenolt	Characterizing and modeling co-infection in Tribolium
Nicholas Ruppe	Mechanisms that regulate do novo telomere addition at a double-strand break
Chloe Stallion	Comparison of genetic and liguistic character of Creolization in the Caribbean
Emily Struttmann	Effects of high-salt conditions on H. pylori
Amanda Sun	Determining the function of Rm62 in resolving R-loops
Raymar Turangan	Immune priming in mosquitoes
Claire Weinstein	The characerization of acinetobacter baumannii sensitivity to novel bacteriophages
Matthew Xin	Characterizing the relationship between p73 and cigarette smoke
Roger Yu	Protein trafficking and membrane biogenesis
Eric Zhang	CK1 in DNA repair and Hhp1 as a model protein
Danzhu Zhao	Quantifying the impact of ACK1 inhibition on the interferon gamma response in melanoma cells
Junqin Zhu	Examining the role of ten elleven translocation enzymes in RNA 5-hydroxymethylcytosine

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• How to Write a Research Proposal | Examples & Templates

How to Write a Research Proposal | Examples & Templates

Published on October 12, 2022 by Shona McCombes and Tegan George. Revised on November 21, 2023.

A research proposal describes what you will investigate, why it’s important, and how you will conduct your research.

The format of a research proposal varies between fields, but most proposals will contain at least these elements:

Introduction

Literature review.

• Research design

Reference list

While the sections may vary, the overall objective is always the same. A research proposal serves as a blueprint and guide for your research plan, helping you get organized and feel confident in the path forward you choose to take.

Table of contents

Research proposal purpose, research proposal examples, research design and methods, contribution to knowledge, research schedule, other interesting articles, frequently asked questions about research proposals.

Academics often have to write research proposals to get funding for their projects. As a student, you might have to write a research proposal as part of a grad school application , or prior to starting your thesis or dissertation .

In addition to helping you figure out what your research can look like, a proposal can also serve to demonstrate why your project is worth pursuing to a funder, educational institution, or supervisor.

Research proposal aims

	Show your reader why your project is interesting, original, and important.
	Demonstrate your comfort and familiarity with your field. Show that you understand the current state of research on your topic.
	Make a case for your . Demonstrate that you have carefully thought about the data, tools, and procedures necessary to conduct your research.
	Confirm that your project is feasible within the timeline of your program or funding deadline.

Research proposal length

The length of a research proposal can vary quite a bit. A bachelor’s or master’s thesis proposal can be just a few pages, while proposals for PhD dissertations or research funding are usually much longer and more detailed. Your supervisor can help you determine the best length for your work.

One trick to get started is to think of your proposal’s structure as a shorter version of your thesis or dissertation , only without the results , conclusion and discussion sections.

Download our research proposal template

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Writing a research proposal can be quite challenging, but a good starting point could be to look at some examples. We’ve included a few for you below.

• Example research proposal #1: “A Conceptual Framework for Scheduling Constraint Management”
• Example research proposal #2: “Medical Students as Mediators of Change in Tobacco Use”

Like your dissertation or thesis, the proposal will usually have a title page that includes:

• The proposed title of your project
• Your supervisor’s name
• Your institution and department

The first part of your proposal is the initial pitch for your project. Make sure it succinctly explains what you want to do and why.

Your introduction should:

• Introduce your topic
• Give necessary background and context
• Outline your  problem statement  and research questions

To guide your introduction , include information about:

• Who could have an interest in the topic (e.g., scientists, policymakers)
• How much is already known about the topic
• What is missing from this current knowledge
• What new insights your research will contribute
• Why you believe this research is worth doing

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As you get started, it’s important to demonstrate that you’re familiar with the most important research on your topic. A strong literature review  shows your reader that your project has a solid foundation in existing knowledge or theory. It also shows that you’re not simply repeating what other people have already done or said, but rather using existing research as a jumping-off point for your own.

In this section, share exactly how your project will contribute to ongoing conversations in the field by:

• Comparing and contrasting the main theories, methods, and debates
• Examining the strengths and weaknesses of different approaches
• Explaining how will you build on, challenge, or synthesize prior scholarship

Following the literature review, restate your main  objectives . This brings the focus back to your own project. Next, your research design or methodology section will describe your overall approach, and the practical steps you will take to answer your research questions.

Building a research proposal methodology

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	, , , )?
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To finish your proposal on a strong note, explore the potential implications of your research for your field. Emphasize again what you aim to contribute and why it matters.

For example, your results might have implications for:

• Improving best practices
• Informing policymaking decisions
• Strengthening a theory or model
• Challenging popular or scientific beliefs
• Creating a basis for future research

Last but not least, your research proposal must include correct citations for every source you have used, compiled in a reference list . To create citations quickly and easily, you can use our free APA citation generator .

Some institutions or funders require a detailed timeline of the project, asking you to forecast what you will do at each stage and how long it may take. While not always required, be sure to check the requirements of your project.

Here’s an example schedule to help you get started. You can also download a template at the button below.

Download our research schedule template

Example research schedule

Research phase	Objectives	Deadline
1. Background research and literature review		20th January
2. Research design planning	and data analysis methods	13th February
3. Data collection and preparation	with selected participants and code interviews	24th March
4. Data analysis	of interview transcripts	22nd April
5. Writing		17th June
6. Revision	final work	28th July

If you are applying for research funding, chances are you will have to include a detailed budget. This shows your estimates of how much each part of your project will cost.

Make sure to check what type of costs the funding body will agree to cover. For each item, include:

• Cost : exactly how much money do you need?
• Justification : why is this cost necessary to complete the research?
• Source : how did you calculate the amount?

To determine your budget, think about:

• Travel costs : do you need to go somewhere to collect your data? How will you get there, and how much time will you need? What will you do there (e.g., interviews, archival research)?
• Materials : do you need access to any tools or technologies?
• Help : do you need to hire any research assistants for the project? What will they do, and how much will you pay them?

If you want to know more about the research process , methodology , research bias , or statistics , make sure to check out some of our other articles with explanations and examples.

Methodology

• Sampling methods
• Simple random sampling
• Stratified sampling
• Cluster sampling
• Likert scales
• Reproducibility

 Statistics

• Null hypothesis
• Statistical power
• Probability distribution
• Effect size
• Poisson distribution

Research bias

• Optimism bias
• Cognitive bias
• Implicit bias
• Hawthorne effect
• Anchoring bias
• Explicit bias

Once you’ve decided on your research objectives , you need to explain them in your paper, at the end of your problem statement .

Keep your research objectives clear and concise, and use appropriate verbs to accurately convey the work that you will carry out for each one.

I will compare …

A research aim is a broad statement indicating the general purpose of your research project. It should appear in your introduction at the end of your problem statement , before your research objectives.

Research objectives are more specific than your research aim. They indicate the specific ways you’ll address the overarching aim.

A PhD, which is short for philosophiae doctor (doctor of philosophy in Latin), is the highest university degree that can be obtained. In a PhD, students spend 3–5 years writing a dissertation , which aims to make a significant, original contribution to current knowledge.

A PhD is intended to prepare students for a career as a researcher, whether that be in academia, the public sector, or the private sector.

A master’s is a 1- or 2-year graduate degree that can prepare you for a variety of careers.

All master’s involve graduate-level coursework. Some are research-intensive and intend to prepare students for further study in a PhD; these usually require their students to write a master’s thesis . Others focus on professional training for a specific career.

Critical thinking refers to the ability to evaluate information and to be aware of biases or assumptions, including your own.

Like information literacy , it involves evaluating arguments, identifying and solving problems in an objective and systematic way, and clearly communicating your ideas.

The best way to remember the difference between a research plan and a research proposal is that they have fundamentally different audiences. A research plan helps you, the researcher, organize your thoughts. On the other hand, a dissertation proposal or research proposal aims to convince others (e.g., a supervisor, a funding body, or a dissertation committee) that your research topic is relevant and worthy of being conducted.

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Research Proposal Examples for Every Science Field

Looking for research funding can be a daunting task, especially when you are starting out. A great way to improve grant-writing skills is to get inspired by winning research proposal examples.

To assist you in writing a competitive proposal, I have curated a collection of real-life research proposal examples from various scientific disciplines. These examples will allow you to gain inspiration about the way research proposals are structured and written.

Structure of a Research Proposal

A research proposal serves as a road-map for a project, outlining the objectives, methodology, resources, and expected outcomes. The main goal of writing a research proposal is to convince funding agency of the value and feasibility of a research project. But a proposal also helps scientists themselves to clarify their planned approach.

While the exact structure may vary depending on the science field and institutional guidelines, a research proposal typically includes the following sections: Problem, Objectives, Methodology, Resources, Participants, Results&Impact, Dissemination, Timeline, and Budget. I will use this structure for the example research proposals in this article.

Here is a brief description of what each of the nine proposal sections should hold.

A concise and informative title that captures the essence of the research proposal. Sometimes an abstract is required that briefly summarizes the proposed project.

Clearly define the research problem or gap in knowledge that the study aims to address. Present relevant background information and cite existing literature to support the need for further investigation.

State the specific objectives and research questions that the study seeks to answer. These objectives should be clear, measurable, and aligned with the problem statement.

Methodology

Describe the research design, methodology, and techniques that will be employed to collect and analyze data. Justify your chosen approach and discuss its strengths and limitations.

Outline the resources required for the successful execution of the research project, such as equipment, facilities, software, and access to specific datasets or archives.

Participants

Describe the research team’s qualification for implementing the research methodology and their complementary value

Results and Impact

Describe the expected results, outcomes, and potential impact of the research. Discuss how the findings will contribute to the field and address the research gap identified earlier.

Dissemination

Explain how the research results will be disseminated to the academic community and wider audiences. This may include publications, conference presentations, workshops, data sharing or collaborations with industry partners.

Develop a realistic timeline that outlines the major milestones and activities of the research project. Consider potential challenges or delays and incorporate contingency plans.

Provide a detailed budget estimate, including anticipated expenses for research materials, equipment, participant compensation, travel, and other relevant costs. Justify the budget based on the project’s scope and requirements.

Consider that the above-mentioned proposal headings can be called differently depending on the funder’s requirements. However, you can be sure in one proposal’s section or another each of the mentioned sections will be included. Whenever provided, always use the proposal structure as required by the funding agency.

Research Proposal template download

This research proposal template includes the nine headings that we just discussed. For each heading, a key sentence skeleton is provided to help you to kick-start the proposal writing process.

Real-Life Research Proposal Examples

Proposals can vary from field to field so I will provide you with research proposal examples proposals in four main branches of science: social sciences, life sciences, physical sciences, and engineering and technology. For each science field, you will be able to download real-life winning research proposal examples.

To illustrate the principle of writing a scientific proposal while adhering to the nine sections I outlined earlier, for each discipline I will also provide you with a sample hypothetical research proposal. These examples are formulated using the key sentence structure that is included in the download template .

In case the research proposal examples I provide do not hold exactly what you are looking for, use the Open Grants database. It holds approved research proposals from various funding agencies in many countries. When looking for research proposals examples in the database, use the filer to search for specific keywords and organize the results to view proposals that have been funded.

Research Proposals Examples in Social Sciences

Here are real-life research proposal examples of funded projects in social sciences.

(Cultural Anthropology)

Here is an outline of a hypothetical Social Sciences research proposal that is structured using the nine proposal sections we discussed earlier. This proposal example is produced using the key sentence skeleton that you will access in the proposal template .

The Influence of Social Media on Political Participation among Young Adults

Social media platforms have become prominent spaces for political discussions and information sharing. However, the impact of social media on political participation among young adults remains a topic of debate.

With the project, we aim to establish the relationship between social media usage and political engagement among young adults. To achieve this aim, we have three specific objectives:

• Examine the association between social media usage patterns and various forms of political participation, such as voting, attending political rallies, and engaging in political discussions.
• Investigate the role of social media in shaping political attitudes, opinions, and behaviors among young adults.
• Provide evidence-based recommendations for utilizing social media platforms to enhance youth political participation.

During the project, a mixed methods approach, combining quantitative surveys and qualitative interviews will be used to determine the impact of social media use on youth political engagement. In particular, surveys will collect data on social media usage, political participation, and attitudes. Interviews will provide in-depth insights into participants’ experiences and perceptions.

The project will use survey software, transcription tools, and statistical analysis software to statistically evaluate the gathered results. The project will also use project funding for participant compensation.

Principal investigator, Jane Goodrich will lead a multidisciplinary research team comprising social scientists, political scientists, and communication experts with expertise in political science and social media research.

The project will contribute to a better understanding of the influence of social media on political participation among young adults, including:

• inform about the association between social media usage and political participation among youth.
• determine the relationship between social media content and political preferences among youth.
• provide guidelines for enhancing youth engagement in democratic processes through social media use.

We will disseminate the research results within policymakers and NGOs through academic publications in peer-reviewed journals, presentations at relevant conferences, and policy briefs.

The project will start will be completed within two years and for the first two objectives a periodic report will be submitted in months 12 and 18.

The total eligible project costs are 58,800 USD, where 15% covers participant recruitment and compensation, 5% covers survey software licenses, 55% are dedicated for salaries, and 25% are intended for dissemination activities.

Research Proposal Examples in Life Sciences

Here are real-life research project examples in life sciences.

(postdoctoral fellowship)
(National Institutes of Environmental Health Sciences)

Here is a hypothetical research proposal example in Life Sciences. Just like the previous example, it consists of the nine discussed proposal sections and it is structured using the key sentence skeleton that you will access in the proposal template .

Investigating the Role of Gut Microbiota in Obesity and Metabolic Syndrome (GUT-MET)

Obesity and metabolic syndrome pose significant health challenges worldwide, leading to numerous chronic diseases and increasing healthcare costs. Despite extensive research, the precise mechanisms underlying these conditions remain incompletely understood. A critical knowledge gap exists regarding the role of gut microbiota in the development and progression of obesity and metabolic syndrome.

With the GUT-MET project, we aim to unravel the complex interactions between gut microbiota and obesity/metabolic syndrome. To achieve this aim, we have the following specific objectives:

• Investigate the composition and diversity of gut microbiota in individuals with obesity and metabolic syndrome.
• Determine the functional role of specific gut microbial species and their metabolites in the pathogenesis of obesity and metabolic syndrome.

During the project, we will employ the following key methodologies:

• Perform comprehensive metagenomic and metabolomic analyses to characterize the gut microbiota and associated metabolic pathways.
• Conduct animal studies to investigate the causal relationship between gut microbiota alterations and the development of obesity and metabolic syndrome.

The project will benefit from state-of-the-art laboratory facilities, including advanced sequencing and analytical equipment, as well as access to a well-established cohort of participants with obesity and metabolic syndrome.

Dr. Emma Johnson, a renowned expert in gut microbiota research and Professor of Molecular Biology at the University of PeerRecognized, will lead the project. Dr. Johnson has published extensively in high-impact journals and has received multiple research grants focused on the gut microbiota and metabolic health.

The project will deliver crucial insights into the role of gut microbiota in obesity and metabolic syndrome. Specifically, it will:

• Identify microbial signatures associated with obesity and metabolic syndrome for potential diagnostic and therapeutic applications.
• Uncover key microbial metabolites and pathways implicated in disease development, enabling the development of targeted interventions.

We will actively disseminate the project results within the scientific community, healthcare professionals, and relevant stakeholders through publications in peer-reviewed journals, presentations at international conferences, and engagement with patient advocacy groups.

The project will be executed over a period of 36 months. Key milestones include data collection and analysis, animal studies, manuscript preparation, and knowledge transfer activities.

The total eligible project costs are $1,500,000, with the budget allocated for 55% personnel, 25% laboratory supplies, 5% data analysis, and 15% knowledge dissemination activities as specified in the research call guidelines.

Research Proposals Examples in Natural Sciences

Here are real-life research proposal examples of funded projects in natural sciences.

(FNU)
(USGS) (Mendenhall Research Fellowship Program)
(Earth Venture Mission – 3 NNH21ZDA002O)

Here is a Natural Sciences research proposal example that is structured using the same nine sections. I created this proposal example using the key sentence skeleton that you will access in the proposal template .

Assessing the Impact of Climate Change on Biodiversity Dynamics in Fragile Ecosystems (CLIM-BIODIV)

Climate change poses a significant threat to global biodiversity, particularly in fragile ecosystems such as tropical rainforests and coral reefs. Understanding the specific impacts of climate change on biodiversity dynamics within these ecosystems is crucial for effective conservation and management strategies. However, there is a knowledge gap regarding the precise mechanisms through which climate change influences species composition, population dynamics, and ecosystem functioning in these vulnerable habitats.

With the CLIM-BIODIV project, we aim to assess the impact of climate change on biodiversity dynamics in fragile ecosystems. To achieve this aim, we have the following specific objectives:

• Investigate how changes in temperature and precipitation patterns influence species distributions and community composition in tropical rainforests.
• Assess the effects of ocean warming and acidification on coral reef ecosystems, including changes in coral bleaching events, species diversity, and ecosystem resilience.
• Conduct field surveys and employ remote sensing techniques to assess changes in species distributions and community composition in tropical rainforests.
• Utilize experimental approaches and long-term monitoring data to evaluate the response of coral reefs to varying temperature and pH conditions.

The project will benefit from access to field sites in ecologically sensitive regions, advanced remote sensing technology, and collaboration with local conservation organizations to facilitate data collection and knowledge sharing.

Dr. Alexander Chen, an established researcher in climate change and biodiversity conservation, will lead the project. Dr. Chen is a Professor of Ecology at the University of Peer Recognized, with a track record of three Nature publications and successful grant applications exceeding 25 million dollars.

The project will provide valuable insights into the impacts of climate change on biodiversity dynamics in fragile ecosystems. It will:

• Enhance our understanding of how tropical rainforest communities respond to climate change, informing targeted conservation strategies.
• Contribute to the identification of vulnerable coral reef ecosystems and guide management practices for their protection and resilience.

We will disseminate the project results to the scientific community, conservation practitioners, and policymakers through publications in reputable journals, participation in international conferences, and engagement with local communities and relevant stakeholders.

The project will commence on March 1, 2024, and will be implemented over a period of 48 months. Key milestones include data collection and analysis, modeling exercises, stakeholder engagement, and knowledge transfer activities. These are summarized in the Gantt chart.

The total eligible project costs are $2,000,000, with budget allocation for research personnel, fieldwork expenses, laboratory analyses, modeling software, data management, and dissemination activities.

Research Proposal Examples in Engineering and Technology

Here are real-life research proposal examples of funded research projects in the field of science and technology.

(USGS) (Mendenhall Postdoctoral Research Fellowship)
(ROSES E.7 (Support for Open Source Tools, Frameworks, and Libraries))

Here is a hypothetical Engineering and Technology research proposal example that is structured using the same nine proposal sections we discussed earlier. I used the key sentence skeleton available in the proposal template to produce this example.

Developing Sustainable Materials for Energy-Efficient Buildings (SUST-BUILD)

The construction industry is a major contributor to global energy consumption and greenhouse gas emissions. Addressing this issue requires the development of sustainable materials that promote energy efficiency in buildings. However, there is a need for innovative engineering solutions to overcome existing challenges related to the performance, cost-effectiveness, and scalability of such materials.

With the SUST-BUILD project, we aim to develop sustainable materials for energy-efficient buildings. Our specific objectives are as follows:

• Design and optimize novel insulating materials with enhanced thermal properties and reduced environmental impact.
• Develop advanced coatings and surface treatments to improve the energy efficiency and durability of building envelopes.
• Conduct extensive material characterization and simulation studies to guide the design and optimization of insulating materials.
• Utilize advanced coating techniques and perform full-scale testing to evaluate the performance and durability of building envelope treatments.

The project will benefit from access to state-of-the-art laboratory facilities, including material testing equipment, thermal analysis tools, and coating application setups. Collaboration with industry partners will facilitate the translation of research findings into practical applications.

Dr. Maria Rodriguez, an experienced researcher in sustainable materials and building technologies, will lead the project. Dr. Rodriguez holds a position as Associate Professor in the Department of Engineering at Peer Recognized University and has a strong publication record and expertise in the field.

The project will deliver tangible outcomes for energy-efficient buildings. It will:

• Develop sustainable insulating materials with superior thermal performance, contributing to reduced energy consumption and greenhouse gas emissions in buildings.
• Introduce advanced coatings and surface treatments developed from sustainable materials that enhance the durability and energy efficiency of building envelopes, thereby improving long-term building performance.

We will disseminate project results to relevant stakeholders, including industry professionals, architects, and policymakers. This will be accomplished through publications in scientific journals, presentations at conferences and seminars, and engagement with industry associations.

The project will commence on September 1, 2024, and will be implemented over a period of 36 months. Key milestones include material development and optimization, performance testing, prototype fabrication, and knowledge transfer activities. The milestones are summarized in the Gantt chart.

The total eligible project costs are $1,800,000. The budget will cover personnel salaries (60%), materials and equipment (10%), laboratory testing (5%), prototyping (15%), data analysis (5%), and dissemination activities (5%) as specified in the research call guidelines.

Final Tips for Writing an Winning Research Proposal

Come up with a good research idea.

Ideas are the currency of research world. I have prepared a 3 step approach that will help you to come up with a research idea that is worth turning into a proposal. You can download the Research Idea Generation Toolkit in this article.

Start with a strong research outline

Before even writing one sentence of the research proposal, I suggest you use the Research Project Canvas . It will help you to first come up with different research ideas and then choose the best one for writing a full research proposal.

Tailor to the requirements of the project funder

Treat the submission guide like a Monk treats the Bible and follow its strict requirements to the last detail. The funder might set requirements for the topic, your experience, employment conditions, host institution, the research team, funding amount, and so forth. 

What you would like to do in the research is irrelevant unless it falls within the boundaries defined by the funder.

Make the reviewer’s job of finding flaws in your proposal difficult by ensuring that you have addressed each requirement clearly. If applicable, you can even use a table with requirements versus your approach. This will make your proposed approach absolutely evident for the reviewers.

Before submitting, assess your proposal using the criteria reviewers have to follow.

Conduct thorough background research

Before writing your research proposal, conduct comprehensive background research to familiarize yourself with existing literature, theories, and methodologies related to your topic. This will help you identify research gaps and formulate research questions that address these gaps. You will also establish competence in the eyes of reviewers by citing relevant literature.

Be concise and clear

Define research questions that are specific, measurable, and aligned with the problem statement.

If you think the reviewers might be from a field outside your own, avoid unnecessary jargon or complex language to help them to understand the proposal better.

Be specific in describing the research methodology. For example, include a brief description of the experimental methods you will rely upon, add a summary of the materials that you are going to use, attach samples of questionnaires that you will use, and include any other proof that demonstrates the thoroughness you have put into developing the research plan. Adding a flowchart is a great way to present the methodology.

Create a realistic timeline and budget

Develop a realistic project timeline that includes key milestones and activities, allowing for potential challenges or delays. Similarly, create a detailed budget estimate that covers all anticipated expenses, ensuring that it aligns with the scope and requirements of your research project. Be transparent and justify your budget allocations.

Demonstrate the significance and potential impact of the research

Clearly articulate the significance of your research and its potential impact on the field. Discuss how your findings can contribute to theory development, practical applications, policy-making, or other relevant areas.

Pay attention to formatting and style guidelines

Follow the formatting and style guidelines provided by your institution or funding agency. Pay attention to details such as font size, margins, referencing style, and section headings. Adhering to these guidelines demonstrates professionalism and attention to detail.

Take a break before editing

After preparing the first draft, set it aside for at least a week. Then thoroughly check it for logic and revise, revise, revise. Use the proposal submission guide to review your proposal against the requirements. Remember to use grammar checking tools to check for errors.

Finally, read the proposal out loud. This will help to ensure good readability.

Seek feedback

Share your proposal with mentors, colleagues, or members of your research community to receive constructive feedback and suggestions for improvement. Take these seriously since they provide a third party view of what is written (instead of what you think you have written).

Reviewing good examples is one of the best ways to learn a new skill. I hope that the research proposal examples in this article will be useful for you to get going with writing your own research proposal.

Have fun with the writing process and I hope your project gets approved!

Learning from research proposal examples alone is not enough

The research proposal examples I provided will help you to improve your grant writing skills. But learning from example proposals alone will take you a rather long time to master writing winning proposals.

To write a winning research proposal, you have to know how to add that elusive X-Factor that convinces the reviewers to move your proposal from the category “good” to the category “support”. This includes creating self-explanatory figures, creating a budget, collaborating with co-authors, and presenting a convincing story.

To write a research proposal that maximizes your chances of receiving research funding, read my book “ Write a Winning Research Proposal “.

This isn’t just a book. It’s a complete research proposal writing toolkit that includes a  project ideation canvas, budget spreadsheet, project rating scorecard, virtual collaboration whiteboard, proposal pitch formula, graphics creation cheat sheet, review checklist and other valuable resources that will help you succeed.

Hey! My name is Martins Zaumanis and I am a materials scientist in Switzerland ( Google Scholar ). As the first person in my family with a PhD, I have first-hand experience of the challenges starting scientists face in academia. With this blog, I want to help young researchers succeed in academia. I call the blog “Peer Recognized”, because peer recognition is what lifts academic careers and pushes science forward.

Besides this blog, I have written the Peer Recognized book series and created the Peer Recognized Academy offering interactive online courses.

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Hi Martins, I’ve recently discovered your content and it is great. I will be implementing much of it into my workflow, as well as using it to teach some graduate courses! I noticed that a materials science-focused proposal could be a very helpful addition.

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How to prepare a Research Proposal

Health research, medical education and clinical practice form the three pillars of modern day medical practice. As one authority rightly put it: ‘Health research is not a luxury, but an essential need that no nation can afford to ignore’. Health research can and should be pursued by a broad range of people. Even if they do not conduct research themselves, they need to grasp the principles of the scientific method to understand the value and limitations of science and to be able to assess and evaluate results of research before applying them. This review paper aims to highlight the essential concepts to the students and beginning researchers and sensitize and motivate the readers to access the vast literature available on research methodologies.

Most students and beginning researchers do not fully understand what a research proposal means, nor do they understand its importance. 1 A research proposal is a detailed description of a proposed study designed to investigate a given problem. 2

A research proposal is intended to convince others that you have a worthwhile research project and that you have the competence and the work-plan to complete it. Broadly the research proposal must address the following questions regardless of your research area and the methodology you choose: What you plan to accomplish, why do you want to do it and how are you going to do it. 1 The aim of this article is to highlight the essential concepts and not to provide extensive details about this topic.

The elements of a research proposal are highlighted below:

1. Title: It should be concise and descriptive. It must be informative and catchy. An effective title not only prick’s the readers interest, but also predisposes him/her favorably towards the proposal. Often titles are stated in terms of a functional relationship, because such titles clearly indicate the independent and dependent variables. 1 The title may need to be revised after completion of writing of the protocol to reflect more closely the sense of the study. 3

2. Abstract: It is a brief summary of approximately 300 words. It should include the main research question, the rationale for the study, the hypothesis (if any) and the method. Descriptions of the method may include the design, procedures, the sample and any instruments that will be used. 1 It should stand on its own, and not refer the reader to points in the project description. 3

3. Introduction: The introduction provides the readers with the background information. Its purpose is to establish a framework for the research, so that readers can understand how it relates to other research. 4 It should answer the question of why the research needs to be done and what will be its relevance. It puts the proposal in context. 3

The introduction typically begins with a statement of the research problem in precise and clear terms. 1

The importance of the statement of the research problem 5 : The statement of the problem is the essential basis for the construction of a research proposal (research objectives, hypotheses, methodology, work plan and budget etc). It is an integral part of selecting a research topic. It will guide and put into sharper focus the research design being considered for solving the problem. It allows the investigator to describe the problem systematically, to reflect on its importance, its priority in the country and region and to point out why the proposed research on the problem should be undertaken. It also facilitates peer review of the research proposal by the funding agencies.

Then it is necessary to provide the context and set the stage for the research question in such a way as to show its necessity and importance. 1 This step is necessary for the investigators to familiarize themselves with existing knowledge about the research problem and to find out whether or not others have investigated the same or similar problems. This step is accomplished by a thorough and critical review of the literature and by personal communication with experts. 5 It helps further understanding of the problem proposed for research and may lead to refining the statement of the problem, to identify the study variables and conceptualize their relationships, and in formulation and selection of a research hypothesis. 5 It ensures that you are not "re-inventing the wheel" and demonstrates your understanding of the research problem. It gives due credit to those who have laid the groundwork for your proposed research. 1 In a proposal, the literature review is generally brief and to the point. The literature selected should be pertinent and relevant. 6

Against this background, you then present the rationale of the proposed study and clearly indicate why it is worth doing.

4. Objectives: Research objectives are the goals to be achieved by conducting the research. 5 They may be stated as ‘general’ and ‘specific’.

The general objective of the research is what is to be accomplished by the research project, for example, to determine whether or not a new vaccine should be incorporated in a public health program.

The specific objectives relate to the specific research questions the investigator wants to answer through the proposed study and may be presented as primary and secondary objectives, for example, primary: To determine the degree of protection that is attributable to the new vaccine in a study population by comparing the vaccinated and unvaccinated groups. 5 Secondary: To study the cost-effectiveness of this programme.

Young investigators are advised to resist the temptation to put too many objectives or over-ambitious objectives that cannot be adequately achieved by the implementation of the protocol. 3

5. Variables: During the planning stage, it is necessary to identify the key variables of the study and their method of measurement and unit of measurement must be clearly indicated. Four types of variables are important in research 5 :

a. Independent variables: variables that are manipulated or treated in a study in order to see what effect differences in them will have on those variables proposed as being dependent on them. The different synonyms for the term ‘independent variable’ which are used in literature are: cause, input, predisposing factor, risk factor, determinant, antecedent, characteristic and attribute.

b. Dependent variables: variables in which changes are results of the level or amount of the independent variable or variables.

Synonyms: effect, outcome, consequence, result, condition, disease.

c. Confounding or intervening variables: variables that should be studied because they may influence or ‘mix’ the effect of the independent variables. For instance, in a study of the effect of measles (independent variable) on child mortality (dependent variable), the nutritional status of the child may play an intervening (confounding) role.

d. Background variables: variables that are so often of relevance in investigations of groups or populations that they should be considered for possible inclusion in the study. For example sex, age, ethnic origin, education, marital status, social status etc.

The objective of research is usually to determine the effect of changes in one or more independent variables on one or more dependent variables. For example, a study may ask "Will alcohol intake (independent variable) have an effect on development of gastric ulcer (dependent variable)?"

Certain variables may not be easy to identify. The characteristics that define these variables must be clearly identified for the purpose of the study.

6. Questions and/ or hypotheses: If you as a researcher know enough to make prediction concerning what you are studying, then the hypothesis may be formulated. A hypothesis can be defined as a tentative prediction or explanation of the relationship between two or more variables. In other words, the hypothesis translates the problem statement into a precise, unambiguous prediction of expected outcomes. Hypotheses are not meant to be haphazard guesses, but should reflect the depth of knowledge, imagination and experience of the investigator. 5 In the process of formulating the hypotheses, all variables relevant to the study must be identified. For example: "Health education involving active participation by mothers will produce more positive changes in child feeding than health education based on lectures". Here the independent variable is types of health education and the dependent variable is changes in child feeding.

A research question poses a relationship between two or more variables but phrases the relationship as a question; a hypothesis represents a declarative statement of the relations between two or more variables. 7

For exploratory or phenomenological research, you may not have any hypothesis (please do not confuse the hypothesis with the statistical null hypothesis). 1 Questions are relevant to normative or census type research (How many of them are there? Is there a relationship between them?). Deciding whether to use questions or hypotheses depends on factors such as the purpose of the study, the nature of the design and methodology, and the audience of the research (at times even the outlook and preference of the committee members, particularly the Chair). 6

7. Methodology: The method section is very important because it tells your research Committee how you plan to tackle your research problem. The guiding principle for writing the Methods section is that it should contain sufficient information for the reader to determine whether the methodology is sound. Some even argue that a good proposal should contain sufficient details for another qualified researcher to implement the study. 1 Indicate the methodological steps you will take to answer every question or to test every hypothesis illustrated in the Questions/hypotheses section. 6 It is vital that you consult a biostatistician during the planning stage of your study, 8 to resolve the methodological issues before submitting the proposal.

This section should include:

Research design: The selection of the research strategy is the core of research design and is probably the single most important decision the investigator has to make. The choice of the strategy, whether descriptive, analytical, experimental, operational or a combination of these depend on a number of considerations, 5 but this choice must be explained in relation to the study objectives. 3

Research subjects or participants: Depending on the type of your study, the following questions should be answered 3 , 5

• - What are the criteria for inclusion or selection?
• - What are the criteria for exclusion?
• - What is the sampling procedure you will use so as to ensure representativeness and reliability of the sample and to minimize sampling errors? The key reason for being concerned with sampling is the issue of validity-both internal and external of the study results. 9
• - Will there be use of controls in your study? Controls or comparison groups are used in scientific research in order to increase the validity of the conclusions. Control groups are necessary in all analytical epidemiological studies, in experimental studies of drug trials, in research on effects of intervention programmes and disease control measures and in many other investigations. Some descriptive studies (studies of existing data, surveys) may not require control groups.
• - What are the criteria for discontinuation?

Sample size: The proposal should provide information and justification (basis on which the sample size is calculated) about sample size in the methodology section. 3 A larger sample size than needed to test the research hypothesis increases the cost and duration of the study and will be unethical if it exposes human subjects to any potential unnecessary risk without additional benefit. A smaller sample size than needed can also be unethical as it exposes human subjects to risk with no benefit to scientific knowledge. Calculation of sample size has been made easy by computer software programmes, but the principles underlying the estimation should be well understood.

Interventions: If an intervention is introduced, a description must be given of the drugs or devices (proprietary names, manufacturer, chemical composition, dose, frequency of administration) if they are already commercially available. If they are in phases of experimentation or are already commercially available but used for other indications, information must be provided on available pre-clinical investigations in animals and/or results of studies already conducted in humans (in such cases, approval of the drug regulatory agency in the country is needed before the study). 3

Ethical issues 3 : Ethical considerations apply to all types of health research. Before the proposal is submitted to the Ethics Committee for approval, two important documents mentioned below (where appropriate) must be appended to the proposal. In additions, there is another vital issue of Conflict of Interest, wherein the researchers should furnish a statement regarding the same.

The Informed consent form (informed decision-making): A consent form, where appropriate, must be developed and attached to the proposal. It should be written in the prospective subjects’ mother tongue and in simple language which can be easily understood by the subject. The use of medical terminology should be avoided as far as possible. Special care is needed when subjects are illiterate. It should explain why the study is being done and why the subject has been asked to participate. It should describe, in sequence, what will happen in the course of the study, giving enough detail for the subject to gain a clear idea of what to expect. It should clarify whether or not the study procedures offer any benefits to the subject or to others, and explain the nature, likelihood and treatment of anticipated discomfort or adverse effects, including psychological and social risks, if any. Where relevant, a comparison with risks posed by standard drugs or treatment must be included. If the risks are unknown or a comparative risk cannot be given it should be so stated. It should indicate that the subject has the right to withdraw from the study at any time without, in any way, affecting his/her further medical care. It should assure the participant of confidentiality of the findings.

Ethics checklist: The proposal must describe the measures that will be undertaken to ensure that the proposed research is carried out in accordance with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical research involving Human Subjects. 10 It must answer the following questions:

• • Is the research design adequate to provide answers to the research question? It is unethical to expose subjects to research that will have no value.
• • Is the method of selection of research subjects justified? The use of vulnerable subjects as research participants needs special justification. Vulnerable subjects include those in prison, minors and persons with mental disability. In international research it is important to mention that the population in which the study is conducted will benefit from any potential outcome of the research and the research is not being conducted solely for the benefit of some other population. Justification is needed for any inducement, financial or otherwise, for the participants to be enrolled in the study.
• • Are the interventions justified, in terms of risk/benefit ratio? Risks are not limited to physical harm. Psychological and social risks must also be considered.
• • For observations made, have measures been taken to ensure confidentiality?

Research setting 5 : The research setting includes all the pertinent facets of the study, such as the population to be studied (sampling frame), the place and time of study.

Study instruments 3 , 5 : Instruments are the tools by which the data are collected. For validated questionnaires/interview schedules, reference to published work should be given and the instrument appended to the proposal. For new a questionnaire which is being designed specifically for your study the details about preparing, precoding and pretesting of questionnaire should be furnished and the document appended to the proposal. Descriptions of other methods of observations like medical examination, laboratory tests and screening procedures is necessary- for established procedures, reference of published work cited but for new or modified procedure, an adequate description is necessary with justification for the same.

Collection of data: A short description of the protocol of data collection. For example, in a study on blood pressure measurement: time of participant arrival, rest for 5p. 10 minutes, which apparatus (standard calibrated) to be used, in which room to take measurement, measurement in sitting or lying down position, how many measurements, measurement in which arm first (whether this is going to be randomized), details of cuff and its placement, who will take the measurement. This minimizes the possibility of confusion, delays and errors.

Data analysis: The description should include the design of the analysis form, plans for processing and coding the data and the choice of the statistical method to be applied to each data. What will be the procedures for accounting for missing, unused or spurious data?

Monitoring, supervision and quality control: Detailed statement about the all logistical issues to satisfy the requirements of Good Clinical Practices (GCP), protocol procedures, responsibilities of each member of the research team, training of study investigators, steps taken to assure quality control (laboratory procedures, equipment calibration etc)

Gantt chart: A Gantt chart is an overview of tasks/proposed activities and a time frame for the same. You put weeks, days or months at one side, and the tasks at the other. You draw fat lines to indicate the period the task will be performed to give a timeline for your research study (take help of tutorial on youtube). 11

Significance of the study: Indicate how your research will refine, revise or extend existing knowledge in the area under investigation. How will it benefit the concerned stakeholders? What could be the larger implications of your research study?

Dissemination of the study results: How do you propose to share the findings of your study with professional peers, practitioners, participants and the funding agency?

Budget: A proposal budget with item wise/activity wise breakdown and justification for the same. Indicate how will the study be financed.

References: The proposal should end with relevant references on the subject. For web based search include the date of access for the cited website, for example: add the sentence "accessed on June 10, 2008".

Appendixes: Include the appropriate appendixes in the proposal. For example: Interview protocols, sample of informed consent forms, cover letters sent to appropriate stakeholders, official letters for permission to conduct research. Regarding original scales or questionnaires, if the instrument is copyrighted then permission in writing to reproduce the instrument from the copyright holder or proof of purchase of the instrument must be submitted.

An Overview of the Discipline

• Molecular biology
• Neurobiology
• Ecology and evolutionary biology
• Computational and mathematical biology

Writing in the Discipline

Writing in the field of biology is purposeful. Grant proposals are written in order to persuade others to provide funding. Papers are published in order to share findings. Biologists write reviews of colleagues' manuscripts to ensure that the research and analysis published in professional journals is valid and substantial. Most often the written work of biologists is motivated by problem definition and solution, but some writing may be devoted to argument and debate. An example of this is debate about nomenclature.

Biology is an explanatory discipline, including explaining how an experiment was conducted and how the data collected establishes or fails to establish a hypothesis. The data must be accurately described, and the reasoning needs to be scientifically sound. Persuasion enters into the writing of biologists in terms of what data they select, how they choose to describe it and, most clearly, in the sections where the biologists must convince colleagues of the importance and implications of their results.

Good evidence is repeatable, relevant to the experiment, and unique from previous experiments. Biologists employ quantitative measurements as well as qualitative observations as evidence. Different subfields may regard different kinds of evidence as legitimate. For example, ecologists may take many data points and use statistical methods to analyze the numbers, while a microbiologist may work with mutant organisms and use the phenotypes as evidence. Evidence is also important for grant proposals. Without strong data, biologists will encounter difficulty in obtaining funding or publishing in well-known journals.

Co-authorship is common in papers that present the findings of an experiment conducted by a group. Scholarly articles, on the other hand, are more commonly authored individually. Scientists must keep up to date on current research so that they can collaborate and build upon what is already known in the field.

Writing Tips

Organization.

Typically student writing assignments follow the conventions of genres in the professional field. However, the organization of a scholarly article may differ because professional journals may have different conventions. In general, scholarly articles begin with an abstract and an introduction that describes the purpose and relevance of the experiment. Procedures and methods are provided, along with detailed results. The author finally offers conclusions from the data and future implications of the findings.

Style Preferences

Biologists prefer shorter sentences to preserve clarity. Similarly, they prefer simple verbs such as show, make, and is. Biologists need to be particularly versatile in terms of writing to particular audiences, for their articles and proposals contain sectionsthere are written to different audiences. For example, the introduction to a grant proposal needs to be written to educated nonspecialists who may make the final funding decision. Being too technical is likely to lose this audience. However, sections on methodology and data need to be written to experts, who may otherwise doubt the credibility of the writer. More importantly, others must be able to reproduce the scholar’s experiment, and this means that readers must have a clear understanding of every aspect of the text. There is no room for ambiguity.

Citation Practices

Biologists use different citation styles depending on the preferences of the journals in which they publish. The three styles most commonly used are:

• Council of Biology Editors' (CBE) Style
• Council of Science Editors' (CSE) Style
• American Psychological Association (APA) Style

Common Errors

• Using active voice rather than passive voice in situations that demand attention to the process rather than the agent of the process. For example, the methods section should focus on the actions such as "The transformed cells were identified using kanamycin” rather than “I found the transformed cells using kanamycin."
• Failing to connect the sections of a paper to unify the piece as a whole.
• Over-interpreting results. Sometimes students may fail to describe the actual results and what they may imply, instead discussing what they would like the results to show.
• Focusing too much on results and failing to draw conclusions from the results.
• Providing unnecessary details or neglecting to provide important details.

Student Assignments

At the undergraduate level, students write lab reports and grant proposals. Some upper-level classes may ask students to write a research proposal. Graduate students are more heavily involved in writing research articles, which outline experiments and prove or disprove hypotheses.

Biology professors encourage students to take classes that require writing. They encourage graduate students to take writing classes as well as have regular writing conferences with their professors.

Professional Writing

While biologists predominantly write research articles, they also write textbook chapters, review articles, and research grants. Biologists, and scientists in general, are compelled to write for a wide range of readers because their grants and papers generally need to convince people from many subfields.

The following link has a list of Penn professors, sorted by subdiscipline, with links to examples of their writing.

Meet the Professors

• What to expect, what to bring
• People at the center
• Drop-in hours and locations
• Schedule an appointment
• Faculty services
• Resources for critical writers
• About Howard Marks
• The writing requirement
• Choosing the right seminar
• What to expect
• Course descriptions
• Transfer credit
• 3808: Journal of Critical Writing
• Other publishing opportunities
• Awards, prizes, and apprenticeships
• Teaching opportunities
• Help with your writing
• Services for faculty
• Important dates, workshops, and training
• Center for Programs in Contemporary Writing
• School of Arts & Sciences
• University of Pennsylvania

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• > Planning, Proposing, and Presenting Science Effectively
• > How to write a research proposal

Book contents

• Frontmatter
• 1 How to plan research
• 2 How to write a research proposal
• 3 How to write a research report
• 4 How to present research
• 5 How to write a curriculum vitae
• Further reading

2 - How to write a research proposal

Published online by Cambridge University Press:  01 September 2010

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• How to write a research proposal
• Jack P. Hailman , University of Wisconsin, Madison , Karen B. Strier , University of Wisconsin, Madison
• Book: Planning, Proposing, and Presenting Science Effectively
• Online publication: 01 September 2010
• Chapter DOI: https://doi.org/10.1017/CBO9780511541469.003

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Thesis proposal example 2

Senior Honors Thesis Research Proposal

Albert B. Ulrich III Thesis Advisor: Dr. Wayne Leibel 11 September 1998

Introduction:

Neotropical fish of the family Cichlidae are a widespread and diverse group of freshwater fish which, through adaptive radiation, have exploited various niches in freshwater ecosystems. One such evolutionary adaptation employed by numerous taxa is miniaturization, an evolutionary process in which a large ancestral form becomes reduced in size to exploit alternative niches. A considerable amount of research has been conducted on the effects of miniaturization on amphibians (Hanken 1983), but although miniaturization has been found to occur in 85 species of freshwater South American fish, little has been done to investigate the effects which miniaturization imposes on the anatomy of the fish (Hanken and Wake 1993).

Background:

Evolution is the process by which species adapt to environmental stresses over time. Nature imposes various selective pressures on ecosystems causing adaptive radiation, where species expand and fill new niches. One such adaptation for a new niche is miniaturization. Miniaturization can be defined as “the evolution of extremely small adult body size within a lineage” (Hanken and Wake 1993). Miniaturization is observed in a variety of taxa, and evolutionary size decreases are observed in mammals and higher vertebrates, but it is more common and more pronounced in reptiles, amphibians and fish (Hanken and Wake 1993). Miniaturization evolved as a specialization which allowed the organisms to avoid selective pressures and occupy a new niche. Miniaturization as a concept is dependent on the phylogenetic assumption that the organism evolved from a larger predecessor. Over time, the miniature organism had to adapt to the new conditions as a tiny species. All of the same basic needs had to be met, but with a smaller body.

In miniature species there is a critical relationship between structure of the body and body size, and frequently this downsizing results in structural and functional changes within the animal (Harrison 1996). Within the concept of miniaturization is the assumption that the species evolved from a larger progenitor. It is necessary then to explore the effects of the miniaturization process. “Miniaturization involves not only small body size per se, but also the consequent and often dramatic effects of extreme size reduction on anatomy, physiology, ecology, life history, and behavior” (Hanken and Wake 1993).

Hanken and Wake 1993 found that the adult skulls of the salamander Thorius were lacking several bones, others were highly underdeveloped, and many species within the genus were toothless. Several invertebrate species display the wholesale loss of major organs systems as a result of the drastic reduction in body size (Hanken and Wake 1993). Hanken and Wake also have shown that morphological novelty is a common result of miniaturization. Morphological novelty, in essence, is the development of new structures in the miniature organism. For example, as body size decreases, certain vital organs will only be able to be reduced by a certain amount and still function. As a result organs such as the inner ear remain large relative to the size of the miniature skull, and structural innovations have to occur in order to support the proportionately large inner ear.

In 1983, James Hanken, at the University of Colorado determined that the adult skull of the Plethodontid salamanders could be characterized by three observations: 1) there was a limited development or even an absence of several ossified elements such as dentition and other bones; 2) there was interspecific and intraspecific variability; 3) there were novel mophological configurations of the braincase and jaw (Hanken 1983).

In his experiments, Hanken found that cranial miniaturization of the Thorius skull was achieved at the expense of ossification. Much of the ossified skeleton was lost or reduced, especially in the anterior elements, which are seen typically in larger adult salamanders (Hanken 1983). In contrast to this ossified downsizing, many of the sensory organs were not diminished in size — therefore present in greater proportion to the rest of the reduced head. He also reported that due to the geometrical space availability, there is a competition for space in reduced sized skulls, and the “predominant brain, otic capsules, and eyes have imposed structural rearrangements on much of the skull that remains” (Hanken 1983).

Hanken proposed that paedomorphosis was the mode of evolution of the plethodontid salamanders (Hanken 1983). Paedomorphosis is the state where the miniaturized structures of the adult salamanders can be described as arrested juvenile states. To support this theory, Hanken showed data where cranial skeletal reduction was less extreme in the posterior regions of the skull. One of the hallmarks of paedamorphosis is the lack of conservation in structures derived late in development. Early developed structures are highly conserved, and the latter derivations become either lost, or greatly reduced. Again, Hanken has shown that elements appearing late in development exhibit greater variation among species than do elements appearing earlier in ontogeny (Hanken 1983). But the presence of novel morphological features cannot be accounted for merely by truncated development and the retention of juvenile traits. Miniature Plethodontid salamanders display features that are not present in other species, juvenile or adult. These novel morphological features are associated with the evolution of decreased size and are postulated to compensate for the reductions occurring in other areas (Hanken 1983).

In 1985, Trueb and Alberch published a paper presenting similar results in their experiments with frogs. They explored the “relationships between body sizes of anurans and their cranial configurations with respect to the degree of ossification of the skull and two ontogenetic variables‹shape and number of differentiation events” (Trueb and Alberch 1985). Trueb and Alberch examined three morphological variables: size, sequence of differentiation events, and shape changes in individual structures. Size and snout length were measured, and the data showed that the more heavily ossified frogs tended to be smaller, whereas the less-ossified species were of average size, contrary to what was hypothesized. But Trueb and Alberch also attributed the diminution in size to paedomorphosis, citing that the smaller frogs lacked one or more of the elements typically associated with anuran skulls‹these missing elements were typically late in the developmental sequence. It is significant to note, however, that although there was an apparent paedomorphic trend, it could not be “applied unequivocally to all anuans” (Trueb and Alberch 1985). Very little research has been done on the effects of miniaturization on fish. In 1993, Buckup published a paper discussing the phylogeny of newly found minature species of Characidiin fish, but the extent of the examination was merely an acknowledgment that the species were indeed miniatures so that they could be taxonomically reclassified ( Buckup 1993). It is this deficit of knowledge with regard to miniaturization in fish that prompts this research.

Statement of the Problem:

How does miniaturization affect other vertebrates, such as fish? There are over 85 species of freshwater South American fish which are regarded as miniature, spanning 5 orders, 11 families and 40 genera (Hanken and Wake 1993). One such species, Apistogramma cacatuoides, is a South American Cichlid native to Peru. It lives in shallow water bodies in the rainforests, where miniature size is necessary. Males in this species reach approximately 8cm, and females only 5cm. This makes A. cacatuoides an ideal specimen for examination. In this senior honors thesis, I intend to examine the effects of miniaturization on cranial morphology of A. cacatuoides.

Plan of Research:

In this thesis, I will compare the cranial anatomy of A. cacatuoides to that of “Cichlasoma” (Archocentrus) nigrofasciatum, a commonly bred fish reared by aquarists known as the Convict Cichlid, a “typical” medium-sized cichlid also of South American origin. The Convicts will be examined at various stages in development, from juvenile to adult, and will be compared to A.cacatuoides.

The first part of this project will involve whole mount preparation of A. cacatuoides, utilizing the staining and clearing procedures described by Taylor and Van Dyke, 1985. This procedure involves the use of Alizarin Red and Alcian Blue to stain bone and cartilage, and takes into account the adaptations and recommendations Proposed in an earlier paper (Hanken and Wassersug 1981). The Taylor and Van Dyke procedure is specifically for the staining and clearing of small fish and other vertebrates. I tested the procedure during last semester¹s Independent Study and made a few minor adjustments to the protocol.

First, the specimens will be placed serially into an absolute ethyl alcohol solution and stained with Alcian Blue. The fish will then be neutralized in a saturated borax solution, transferred to a 20% hydrogen peroxide solution in potassium hydroxide, and then bleached under a fluorescent light. The unwanted soft tissues will then be cleared using trypsin powder, and then stained in KOH again with alizarin red. The final preparation of the fish involves rinsing the fish, and placing them serially into 40%, 70%, and finally 100% glycerin.

Following the above preparation of the specimens, the crania of the A. cacatuoides specimens will be examined for morphological variation and compared to the cranial anatomy of the Convict cichlid as a progenitor reference point examined at various developmental stages to see if paedomorphosis in indeed the mechanism of miniaturization in A. cacatuoides.

Expected Costs:

The project is estimated to cost no more that five hundred dollars for chemicals and supplies for the entire year.

Literature Cited:

Hanken, J., 1983. Miniaturization and its Effects on Cranial Morphology in Plethodontid Salamanders, Genus Thorius (Amphibia: Plethodontidae). I. Osteological Variation”. Biological Journal of the Linnean Society (London) 23: 55-75.

Hanken, James, 1983. Miniaturization and its Effects on Cranial Morhology in Plethodontid Salamanders, Genus Thorius (Amphibia, Plethodintidae): II.The Fate of the Brain and Sense Organs and Their Role in Skull Morphogenesis and Evolution . Journal of Morphology 177: 255-268.

Hanken, James and David Wake, 1993. Miniaturization of Body Size: Origanismal Consequences and Evolutionary Significance. Annual Review of Ecological Systems 24: 501-19.

Harrison, I. J., 1996. Interface Areas in Small Fish. Zoological Symposium No. 69. The Zoological Society of London: London.

Miller, P. J., 1996. Miniature Vertebrates: The Implications of Small Body Size. Symposium of the Zoological Society of London. No. 69: 15-45.

Taylor, William R. and George Van Dyke, 1985. Revised Procedures for Staining and Clearing Small Fishes and Other Vertebrates for Small Bone and Cartilage Study. Cybium. 9(2): 107-119.

Trueb, L. and P. Alberch, 1985. Miniaturization and the Anuran Skull: a Case Study of Heterochrony. Fortschritte der Zoologie. Bund 30.

Williams, T. Walley, 1941 Bone and Cartilage. Stain. Tech. 16:23-25.

: Research Proposal

• How it works

Published by Robert Bruce at August 29th, 2023 , Revised On September 5, 2023

Biology Research Topics

Are you in need of captivating and achievable research topics within the field of biology? Your quest for the best biology topics ends right here as this article furnishes you with 100 distinctive and original concepts for biology research, laying the groundwork for your research endeavor.

Table of Contents

Our proficient researchers have thoughtfully curated these biology research themes, considering the substantial body of literature accessible and the prevailing gaps in research.

Should none of these topics elicit enthusiasm, our specialists are equally capable of proposing tailor-made research ideas in biology, finely tuned to cater to your requirements. 

Thus, without further delay, we present our compilation of biology research topics crafted to accommodate students and researchers.

Research Topics in Marine Biology

• Impact of climate change on coral reef ecosystems.
• Biodiversity and adaptation of deep-sea organisms.
• Effects of pollution on marine life and ecosystems.
• Role of marine protected areas in conserving biodiversity.
• Microplastics in marine environments: sources, impacts, and mitigation.

Biological Anthropology Research Topics

• Evolutionary implications of early human migration patterns.
• Genetic and environmental factors influencing human height variation.
• Cultural evolution and its impact on human societies.
• Paleoanthropological insights into human dietary adaptations.
• Genetic diversity and population history of indigenous communities.

Biological Psychology Research Topics 

• Neurobiological basis of addiction and its treatment.
• Impact of stress on brain structure and function.
• Genetic and environmental influences on mental health disorders.
• Neural mechanisms underlying emotions and emotional regulation.
• Role of the gut-brain axis in psychological well-being.

Cancer Biology Research Topics 

• Targeted therapies in precision cancer medicine.
• Tumor microenvironment and its influence on cancer progression.
• Epigenetic modifications in cancer development and therapy.
• Immune checkpoint inhibitors and their role in cancer immunotherapy.
• Early detection and diagnosis strategies for various types of cancer.

Also read: Cancer research topics

Cell Biology Research Topics

• Mechanisms of autophagy and its implications in health and disease.
• Intracellular transport and organelle dynamics in cell function.
• Role of cell signaling pathways in cellular response to external stimuli.
• Cell cycle regulation and its relevance to cancer development.
• Cellular mechanisms of apoptosis and programmed cell death.

Developmental Biology Research Topics 

• Genetic and molecular basis of limb development in vertebrates.
• Evolution of embryonic development and its impact on morphological diversity.
• Stem cell therapy and regenerative medicine approaches.
• Mechanisms of organogenesis and tissue regeneration in animals.
• Role of non-coding RNAs in developmental processes.

Also read: Education research topics

Human Biology Research Topics

• Genetic factors influencing susceptibility to infectious diseases.
• Human microbiome and its impact on health and disease.
• Genetic basis of rare and common human diseases.
• Genetic and environmental factors contributing to aging.
• Impact of lifestyle and diet on human health and longevity.

Molecular Biology Research Topics 

• CRISPR-Cas gene editing technology and its applications.
• Non-coding RNAs as regulators of gene expression.
• Role of epigenetics in gene regulation and disease.
• Mechanisms of DNA repair and genome stability.
• Molecular basis of cellular metabolism and energy production.

Research Topics in Biology for Undergraduates

• 41. Investigating the effects of pollutants on local plant species.
• Microbial diversity and ecosystem functioning in a specific habitat.
• Understanding the genetics of antibiotic resistance in bacteria.
• Impact of urbanization on bird populations and biodiversity.
• Investigating the role of pheromones in insect communication.

Synthetic Biology Research Topics 

• Design and construction of synthetic biological circuits.
• Synthetic biology applications in biofuel production.
• Ethical considerations in synthetic biology research and applications.
• Synthetic biology approaches to engineering novel enzymes.
• Creating synthetic organisms with modified functions and capabilities.

Animal Biology Research Topics 

• Evolution of mating behaviors in animal species.
• Genetic basis of color variation in butterfly wings.
• Impact of habitat fragmentation on amphibian populations.
• Behavior and communication in social insect colonies.
• Adaptations of marine mammals to aquatic environments.

Also read: Nursing research topics

Best Biology Research Topics 

• Unraveling the mysteries of circadian rhythms in organisms.
• Investigating the ecological significance of cryptic coloration.
• Evolution of venomous animals and their prey.
• The role of endosymbiosis in the evolution of eukaryotic cells.
• Exploring the potential of extremophiles in biotechnology.

Biological Psychology Research Paper Topics

• Neurobiological mechanisms underlying memory formation.
• Impact of sleep disorders on cognitive function and mental health.
• Biological basis of personality traits and behavior.
• Neural correlates of emotions and emotional disorders.
• Role of neuroplasticity in brain recovery after injury.

Biological Science Research Topics: 

• Role of gut microbiota in immune system development.
• Molecular mechanisms of gene regulation during development.
• Impact of climate change on insect population dynamics.
• Genetic basis of neurodegenerative diseases like Alzheimer’s.
• Evolutionary relationships among vertebrate species based on DNA analysis.

Biology Education Research Topics 

• Effectiveness of inquiry-based learning in biology classrooms.
• Assessing the impact of virtual labs on student understanding of biology concepts.
• Gender disparities in science education and strategies for closing the gap.
• Role of outdoor education in enhancing students’ ecological awareness.
• Integrating technology in biology education: challenges and opportunities.

Biology-Related Research Topics

• The intersection of ecology and economics in conservation planning.
• Molecular basis of antibiotic resistance in pathogenic bacteria.
• Implications of genetic modification of crops for food security.
• Evolutionary perspectives on cooperation and altruism in animal behavior.
• Environmental impacts of genetically modified organisms (GMOs).

Biology Research Proposal Topics

• Investigating the role of microRNAs in cancer progression.
• Exploring the effects of pollution on aquatic biodiversity.
• Developing a gene therapy approach for a genetic disorder.
• Assessing the potential of natural compounds as anti-inflammatory agents.
• Studying the molecular basis of cellular senescence and aging.

Biology Research Topic Ideas

• Role of pheromones in insect mate selection and behavior.
• Investigating the molecular basis of neurodevelopmental disorders.
• Impact of climate change on plant-pollinator interactions.
• Genetic diversity and conservation of endangered species.
• Evolutionary patterns in mimicry and camouflage in organisms.

Biology Research Topics for Undergraduates 

• Effects of different fertilizers on plant growth and soil health.
• Investigating the biodiversity of a local freshwater ecosystem.
• Evolutionary origins of a specific animal adaptation.
• Genetic diversity and disease susceptibility in human populations.
• Role of specific genes in regulating the immune response.

Cell and Molecular Biology Research Topics 

• Molecular mechanisms of DNA replication and repair.
• Role of microRNAs in post-transcriptional gene regulation.
• Investigating the cell cycle and its control mechanisms.
• Molecular basis of mitochondrial diseases and therapies.
• Cellular responses to oxidative stress and their implications in ageing.

These topics cover a broad range of subjects within biology, offering plenty of options for research projects. Remember that you can further refine these topics based on your specific interests and research goals.

Frequently Asked Questions 

What are some good research topics in biology?

A good research topic in biology will address a specific problem in any of the several areas of biology, such as marine biology, molecular biology, cellular biology, animal biology, or cancer biology.

A topic that enables you to investigate a problem in any area of biology will help you make a meaningful contribution. 

How to choose a research topic in biology?

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• Consider your areas of knowledge and personal passions. 
• Conduct a thorough review of existing literature.
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• Narrow down and refine your research query. 
• Remain receptive to new ideas and suggestions.

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Top 11 Biology Research Proposal Ideas with Samples and Examples (Free PDF Attached)

Hanisha Kapoor

“Cancer cure is finally here! Doctors found the miracle drug! Cancer in all patients vanishes,” these have been some screaming headlines in newspapers in 2022. Even as the discovery of the cure (with many qualifiers as of now) is a miraculous achievement, it took real hard work.

At the centre of any sublime achievement in health sciences is a team of world-class researchers and doctors, who worked hard to draft a biology research proposal idea that got the nod of funding agencies. In the specific example cited above, Dostarlimab, was the drug that was researched.

What we illustrate through this study is the necessity and essentiality of crafting a research proposal that meets its goals and outperforms competition.

Explore this guide to write an impeccable research proposal to ensure you always write a winning proposition, and turn ideas into reality.

In this blog, we study the nuts and bolts of a well-structured presentation. The thing to ensure is that the research proposal covers all bases and leaves nothing to chance.

Biology Research Proposal Ideas Templates to Get Funded for New Discoveries and Advancements

If you want to project new developments and innovation that your research will bring to life, perk up your presentations with SlideTeam’s well-designed PPT Templates. Whether it is about showcasing different experiments or drug testing, incorporate our ready-made PPT Templates to gain that extra edge and purpose.

Persuade reviewers to support your findings using our actionable PowerPoint diagrams.

Writing a thorough dissertation proposal is a stepping stone to excelling in your academic projects. Read this blog and learn more on structuring your thesis.

Browse this collection of PowerPoint slides to make a substantial positive impact on how your research proposal is seen.

Let's begin!

Template 1: Biology Research Proposal PowerPoint Template

This is a 29-slide research proposal PPT diagram to help you put forth your ideas and discoveries in the field of biology. Use these well-crafted PowerPoint Templates to give your audience an overview of the project. You can also showcase steps of your research process, requirements, and other capabilities for completing the study. This ready-made PowerPoint Deck also comprises a slide on Budgeting to help you convince your reviewers to sanction that grant. Download this PPT Template now!

Download this template

Template 2: Biology Cover Letter Research Proposal Idea PPT Slide

As the adage goes, First Impression is the Last Impression . Ensure that you leave a long-lasting impression on your audience with the showcasing of your new research using this engaging PPT Template. Deploy a predesigned and easy-to-use PowerPoint Layout to pitch your client your project idea. Get a head-start from your reviewer and dig deeper into your research with this template as the reference. Download now!

Grab this slide

Template 3: Vision and Mission for Biology Research Proposal PowerPoint Graphic

Want to showcase the aim and goal of your research project? Get this content-ready PPT Template to pen down the vision and mission of your biology research proposal project. Present your future goals and expectations from this study with this fully editable PowerPoint Slide and help your audience comprehend your mission for this project. This PPT diagram can easily be downloaded. Just click the link below and use it as per requirements.

Grab this template

Template 4: Biology Project Objectives PowerPoint Template

What you plan to achieve by the end of the project is what matters the most to the reviewers. Thus, ensure that you highlight the project objectives, which include timelines, budget, etc., with this content-ready PowerPoint Template. Leave no scope for error and uncertainties in your proposal. Get your audience on board with you on your research idea using this customizable PPT slide. Download now!

Template 5: Biology Research Idea Context PPT Diagram

Here is another ready-to-use PowerPoint Template that helps you with the framework of how to contextualize your project. Walk your audience through the strategies you plan to execute to create practical solutions to the problems. Incorporate this fully editable PPT diagram and highlight the best possible treatment, medicines, vaccinations, etc., to combat disease. Use this custom-made PowerPoint Slide and present your detailed study with confidence. Grab this slide now!

Template 6: Methods for Biology Research Proposal PowerPoint Slide

This ready-made PowerPoint Diagram is well designed to help you demonstrate actionable methods that fight diseases. Be methodical and explain each process using this PPT design. Convince reviewers and ensure to get funded for your research with this customizable PowerPoint Graphic. Download now!

Template 7: Roadmap Biology PowerPoint Template

Deploy this preset as a communication tool to draw a painting review of your action plan. Define major tasks and goals and lay out your strategies to achieve those targets. This roadmap PPT Template helps showcase major steps and milestones in your journey. Use this ready-made PowerPoint Graphic as a guide to keep everyone in your team informed on the project status. Download now!

Template 8: Gantt Chart Research Proposal PowerPoint Design

Wish to complete your project on time? Grab this actionable PowerPoint Template and set dates and times for each task. This PPT Template also allows you to keep track of business activities and ensure your project’s timely completion . It is a customizable PowerPoint Diagram to help you change time and date as per requirements. Grab this useful PowerPoint Layout now!

Template 9: Budget Research Proposal PPT Diagram

Struggling to create a budget for your research proposal idea? How about using this illustration to outline a detailed expected project cost? This PPT Template helps you list all activities and the estimated cost of each. Justify your budget and get approval from your stakeholders using this customized PPT Diagram. Download now!

Template 10: Next Steps for Biology Research Proposal PowerPoint Template

Want to seal the deal with researchers for your next biology project? Use this content-ready PowerPoint Template and state the next steps for your study in a professional manner. This PPT Diagram also allows you to include some content. Use this template to  convince your reviewers that you are a step ahead of all possible negative scenarios. Download now!

BONUS SLIDE

Contact us biology research ppt side.

It is impolite not to leave your contact number for your researchers or stakeholders. Thus, ensure you provide a point of contact so that your clients reach out to you without any inconvenience. Deploy this neat, clutter-free PPT Slide to add your address, phone number, and email id. It is a custom-made slide. You can use it as per requirement. Download now!

Justifying and presenting practical ways to study a research problem is a task. Thus, ease the burden and incorporate SlideTeam's ready-made research proposal presentation PPT Templates to showcase your analysis and in-depth research on a subject. These handy PowerPoint Diagrams can be customized with a single click. Download these ready-made and premium PowerPoint Slides from our monthly, semi-annual, annual, annual + custom design subscriptions here .

PS: Wish to present your scholarly literature review in a concise and easy manner? Explore this exclusive guide replete with literature review templates to make sure you reach the public as well, with your authoritative point of view.

FAQs On   Biology Research Proposal Ideas

How to write a research proposal in biology.

Every research proposal is unique and aims to tackle a specific problem statement or hypothesis. It should focus on potentially valuable outcomes, fill in the gaps, and lead to progress of Scientific Knowledge in general. In biology, of course, there is still endless ground to cover in terms of our ability to tackle diseases; the Covid-19 pandemic brought out all our inadequacies to the fore as well.

As the starting point for any effort to improve things, writing an effective research proposal in biology is the key skill to inculcate for hard-core researchers and the academia. Given below are the five key steps we need to master before we put pen to paper for a biology research paper that rocks.

• Study the existing literature
• Narrow the topic down
• Identify keywords
• Formulate the topic

What is the purpose of research in the field of Biology?

Biological scientists conduct research to gain better understanding of life processes and apply that understanding to developing new products and processes. Here, the aim is to know better and deeper, and work to develop novel solutions to diseases. Remember, disease prevention is even more important than developing cures.

How long should a biology proposal be?

A focused and extensive thesis proposal should not be longer than 12 pages of text. Figures and data can be presented on additional pages, if these are critical to the persuasive pitch. Please remember it is purpose of the research proposal, its organization of information and the real-life connect it has that gets it the money. Length of the proposal is required, but a part of the format that every other researcher will have to comply to. You shine when your problem statement and hypothesis are the most relevant.

What are the features of a successful biology research proposal?

A good research proposal must:

• Cover the basics
• Describe the relevance
• Focus on the significance of the research
• Explain the approach
• Highlight your expertise

In short, explaining your approach in a relevant manner is the key differentiator that mark out the successful projects as a class apart. Your sincerity of purpose and attention to detail also has to be evident when it is show-time for presentations.

Download the free Biology Research Proposal .

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Biological Anthropology

Status: archived, archived funding opportunity, important information for proposers.

All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements. Submitting a proposal prior to a specified deadline does not negate this requirement.

Supports field, laboratory and computational research on human and nonhuman primate adaptation, variation and evolution to advance knowledge about human origins and the dynamics between biology and culture.

The Biological Anthropology Program supports basic research in areas related to human evolution and contemporary human biological variation. Research areas supported by the program include, but are not limited to, human genetic variation, human and nonhuman primate ecology and adaptability, human osteology and bone biology, human and nonhuman primate paleontology, functional anatomy, and primate socioecology. Grants supported in these areas are united by an underlying evolutionary framework, and often by a consideration of adaptation as a central theoretical theme. Proposals may also have a biocultural or bioarchaeological orientation. The program frequently serves as a bridge within NSF between the social and behavioral sciences and the natural and physical sciences, and proposals commonly are jointly reviewed and funded with other programs.

For more information about Multidisciplinary Research and Training Opportunities, please visit the SBE Office of Multidisciplinary Activities web site .

For additional, specific information on the Biological Anthropology Doctoral Dissertation Research Improvement Grants (DDRIGs) solicitation, please visit the Biological Anthropology DDRIG program web site .

Program contacts

Program Director

	(703) 292-7850	SBE/SES
Program Director		(703)-292-7758
Program Specialist		(703) 292-4636	SBE/BCS

Additional program resources

• Dear Colleague Letter: Non-Academic Research Internships for Graduate Students (INTERN) Supplemental Funding Opportunity (NSF 21-013)
• Dear Colleague Letter: A Broader Impacts Framework for Proposals Submitted to NSF's Social, Behavioral, and Economic Sciences Directorate (NSF 21-059)
• NSF programs to stop accepting proposals via FastLane website

Awards made through this program

Related programs.

• Biological Anthropology Program - Doctoral Dissertation Research Improvement Grants (BA-DDRIG)
• High-Risk Research in Biological Anthropology and Archaeology (HRRBAA)
• NSF Graduate Research Fellowship Program (GRFP)
• SBE Postdoctoral Research Fellowships (SPRF)
• Faculty Early Career Development Program (CAREER)
• Mid-Career Advancement (MCA)
• ADVANCE: Organizational Change for Gender Equity in STEM Academic Professions (ADVANCE)
• Build and Broaden: Enhancing Social, Behavioral and Economic Science Research and Capacity at Minority-Serving Institutions (B2)
• Research Experiences for Undergraduates (REU)
• Facilitating Research at Primarily Undergraduate Institutions:
• Major Research Instrumentation Program (MRI)
• Archaeology and Archaeometry
• Archaeology Program - Doctoral Dissertation Research Improvement Grants (Arch-DDRIG)
• Cultural Anthropology
• Cultural Anthropology Program - Doctoral Dissertation Research Improvement Grants (CA-DDRIG)
• Human Networks and Data Science (HNDS)

Organization(s)

• Directorate for Social, Behavioral and Economic Sciences (SBE)
• Division of Behavioral and Cognitive Sciences (SBE/BCS)

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Guest Essay

The Long-Overlooked Molecule That Will Define a Generation of Science

By Thomas Cech

Dr. Cech is a biochemist and the author of the forthcoming book “The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets,” from which this essay is adapted.

From E=mc² to splitting the atom to the invention of the transistor, the first half of the 20th century was dominated by breakthroughs in physics.

Then, in the early 1950s, biology began to nudge physics out of the scientific spotlight — and when I say “biology,” what I really mean is DNA. The momentous discovery of the DNA double helix in 1953 more or less ushered in a new era in science that culminated in the Human Genome Project, completed in 2003, which decoded all of our DNA into a biological blueprint of humankind.

DNA has received an immense amount of attention. And while the double helix was certainly groundbreaking in its time, the current generation of scientific history will be defined by a different (and, until recently, lesser-known) molecule — one that I believe will play an even bigger role in furthering our understanding of human life: RNA.

You may remember learning about RNA (ribonucleic acid) back in your high school biology class as the messenger that carries information stored in DNA to instruct the formation of proteins. Such messenger RNA, mRNA for short, recently entered the mainstream conversation thanks to the role they played in the Covid-19 vaccines. But RNA is much more than a messenger, as critical as that function may be.

Other types of RNA, called “noncoding” RNAs, are a tiny biological powerhouse that can help to treat and cure deadly diseases, unlock the potential of the human genome and solve one of the most enduring mysteries of science: explaining the origins of all life on our planet.

Though it is a linchpin of every living thing on Earth, RNA was misunderstood and underappreciated for decades — often dismissed as nothing more than a biochemical backup singer, slaving away in obscurity in the shadows of the diva, DNA. I know that firsthand: I was slaving away in obscurity on its behalf.

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Spatial Perspective Taking is Distinct from Cognitive and Affective Perspective Taking

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Perspective taking (PT) is the ability to imagine viewpoints different from our own. However, the nature of PT as a construct, and its underlying cognitive mechanisms, are not well established. Some researchers propose that understanding what others believe (cognitive PT), feel (affective PT), and see (spatial PT) form a single behavioral dimension, relying on the orienting of attention between competing frame-of-reference representations. Others propose that PT mechanisms are dissociable, although there are three different proposals about such dissociations. The present study examined behavioral associations among measures of spatial, cognitive, and affective PT and attentional control in neurotypical young adults. There was a lack of convergent validity for measures of cognitive and affective PT, pointing to the need for more psychometric work on these dimensions. Much better convergence was found for spatial PT measures. There was little to no behavioral association between spatial PT and either social forms of PT (cognitive or affective) or attentional control measures. This pattern suggests support for a dissociated model in which spatial PT is a distinct cognitive construct.

Competing Interest Statement

The authors have declared no competing interest.

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2024 Experimental Human Biology Request for Proposals

The Stanford Innovative Medicines Accelerator (IMA) is accepting proposals to address unmet therapeutic needs through human subjects research. Through this solicitation, the IMA seeks to support human subjects research that is ripe for translation by fostering the clinical development of new or extending the use of existing drugs, vaccines, and companion biomarkers that directly enable drug development. This could be a proof of concept trial for a new medication, a new indication for an existing proprietary or generic drug, or a companion biomarker.  We prioritize projects that will generate data to take projects towards external funding for product development. Investigators should be motivated to engage in the clinical and product development process with the IMA. Successful IMA projects have led to the formation of new companies, license agreements with biotech or pharma companies, sponsored research agreements, and grant funding for clinical follow-on studies. Please see the  pipeline for currently supported projects.  

Of particular interest are projects that seek to:

• Evaluate an approved drug or investigational drug candidate in a new indication
• Evaluate the utility of an approved molecular imaging tool in a secondary indication
• Evaluate a companion biomarker for enabling precision medicine use of an approved or investigational drug or for improving surgical outcomes

Selection Process & Timeline:

Proposals will be reviewed by evaluators knowledgeable in translational medicine and evaluated according to the following criteria:

• Novelty and significance of the hypothesis 
• Severity of the unmet medical need
• Feasibility of the proposed study
• Potential for success of the project’s longer-term objectives
• Availability of relevant IMA resources

PIs whose project ideas are selected will be invited to submit full protocols including detailed budgets, which will be developed collaboratively with the Experimental Human Biology team. Final funding decisions are contingent upon a full protocol review, including an evaluation of the feasibility of all regulatory and contractual aspects of the proposed research. Projects that achieve pre-defined milestones may be eligible for additional follow-on funding to continue supporting the clinical trial. 

Letters of Intent are due July 31, 2024. 

All Stanford faculty with PI eligibility, including faculty in the Clinical Educator line, are welcome to apply. 

Submit a letter of intent as a PDF (Arial, 11 point font, 0.5 inch margins, limit 4 pages) containing:

• A list of investigators. Each team must include a physician and a statistician. Please contact the IMA program manager for assistance with finding a statistician if needed.
• Briefly describe the objective of the overall project and the goal of the proposed study. Include the unmet medical need, current standard of care, and how the study outcome supports the stated goal. Example goals: enabling follow-on clinical studies, external license or partnership with an existing company, a new company, or a new drug campaign. Applicants are encouraged to consult the program manager about how the value proposition fits within the IMA mission.
• Project description in the format of a Protocol Synopsis, including at a minimum the rationale, indication, key objectives, study endpoints, planned enrollment, and inclusion/exclusion criteria for subjects enrolled in the study.
• Timeline outlining the entire clinical development plan required to bring the final product to patients. Indicate where the project currently stands, what is requested of IMA, and how IMA support fits into the development timeline. State clear go/no-go milestones and dependencies that will ensure the feasibility of achieving the targeted deliverable. 
• Total trial cost and budget. Please indicate which areas you are requesting in-kind IMA staffing or financial support from IMA. Please note that the IMA cannot support faculty/PI effort. 

Letters of Intent should be submitted directly to the Sarafan ChEM-H SlideRoom portal:  https://chemh.slideroom.com/#/permalink/program/78751   Applicants do not need to submit the LOI to the Research Management Group (RMG) or Office of Sponsored Research (OSR). 

The IMA seeks to translate promising academic science to a clinical setting. The IMA provides drug and clinical development expertise, financial support, and in-kind resources. We have supported projects in the range of $100K to $1M. For substantial resource needs, the IMA works with the PI to identify scaling partners to defray costs and support continued clinical development. Funds and in-kind resources will be released at key go/no-go milestones, e.g. FDA/IRB/SRC approval, interim enrollment goal, and full study enrollment. Please note that the IMA cannot support faculty/PI effort. 

In-kind IMA staff support may include:

• Study planning and operations : The IMA team assists with protocol development, study start-up activities, monitoring, EDC database build and testing, and clinical research coordination activities.
• Regulatory submissions:  The IMA team interfaces with regulatory consultants, the FDA, IRB, and SRC administrative boards. 
• Project management: The IMA team supports project planning, budgeting, and identifying outsourcing opportunities.
• Access to resources: The IMA team connects to external alliances and Contract Research Organizations (CROs) to meet project needs.

Please indicate the type of support needed in the budget justification. Specific roles and responsibilities of personnel support and financial allocations will be described in award letters issued to selected projects. The specific level of support will vary by project need. Projects that achieve pre-defined milestones may be eligible for additional follow-on funding.

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