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Clinical microbiology articles from across Nature Portfolio
Latest research and reviews.
Bidirectional Mendelian randomization links gut microbiota to primary biliary cholangitis
- Zhijia Zhou
Natal factors influencing newborn’s oral microbiome diversity
- Yoon-Hee Kim
- Tae yang Lee
- Chung-Min Kang
The role of antibiotic-derived mycobacterial vesicles in tuberculosis pathogenesis
- C. J. Davids
- K. Umashankar-Rao
- Gabriela Godaly
Polymicrobial infection in cystic fibrosis and future perspectives for improving Mycobacterium abscessus drug discovery
- Emily, J. Baker
- Gemma Allcott
- Jonathan A. G. Cox
Characterization of variably protease-sensitive prionopathy by capillary electrophoresis
- Jennifer Myskiw
- Ben A. Bailey-Elkin
- Stephanie A Booth
Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discovery
Metagenomic next-generation sequencing has the potential to support diagnosis of unknown infections as it can identify all potential pathogens without requiring a prior suspected cause. Here, the authors develop and clinically validate a metagenomics-based assay for common and novel respiratory viral pathogens.
- Jessica Karielle Tan
- Venice Servellita
- Charles Y. Chiu
News and Comment
Uncovering the hpv types causing cervical cancer.
- Fernando Dias Gonçalves Lima
- Mariano A. Molina
The meaning of oral bacteria in faeces
Our study investigated microbial dynamics involved in the relative enrichment of oral bacteria in faeces. Results in mice and from human patients indicated that high percentages of oral bacteria reflect a depleted gut microbiota, with oral bacteria simply passing through rather than expanding in the gut, which has implications for gastrointestinal disease treatment.
Resisting weight gain with prebiotic fibre
Resistant starch is a prebiotic fibre that is fermented by the gut microbiota and leads to benefits for host physiology. A clinical trial in Nature Metabolism demonstrates weight loss when resistant starch was given to individuals with excess weight.
- Matthew M. Carter
- Sean P. Spencer
The contribution of human conflict to the development of antimicrobial resistance
Pallett et al. discuss the impact of human conflict on development of antimicrobial resistance. They overview approaches to limit the spread of antimicrobial resistance, using the ongoing conflict in Ukraine as an example of the challenges and opportunities.
- Scott J. C. Pallett
- Sara E. Boyd
- Emma J. Hutley
In vitro activity of cefiderocol in combination with new β-lactam/β-lactamase inhibitor combinations (βL-βLICs) against multidrug resistant KPC-producing Klebsiella pneumoniae
- Paolo Gaibani
- Tiziana Lazzarotto
- Simone Ambretti
Doxycycline-PEP — novel and promising but needs monitoring
Sexually transmitted infections (STIs) remain public health concerns. Doxycycline post-exposure prophylaxis to prevent STIs is a novel promising intervention, which in a new study caused an ∼65% reduction in incident STIs. However, long-term effects on STI prevalence, microbiomes and antimicrobial resistance among STI pathogens, non-STI pathogens and commensals need to be monitored.
- Magnus Unemo
- Fabian Yuh Shiong Kong
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