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Exercise for Osteoarthritis: A Literature Review of Pathology and
In the present paper, the pathological mechanism of exercise in OA treatment was summarized through the induction of relevant literature, as shown in Table 1. Exercise relieves the pathological changes of OA by affecting the degradation of the ECM, apoptosis, inflammatory response, autophagy, and changes of ncRNA.
Osteoarthritis: a narrative review of molecular approaches to disease
Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still believed to be a mechanically driven disease, the role of underlying co-existing inflammatory processes and mediators in the onset of OA and its progression is now more appreciated. Post-traumatic ...
Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non
1. Introduction. Osteoarthritis (OA) is the most common progressive musculoskeletal condition that can affect joints, but it mainly affects the hips and knees as predominant weight-bearing joints [1,2,3].Knee osteoarthritis is characterized by structural modifications to primarily articular cartilage and the subchondral bone, but also Hoffa's fat pad, synovia, ligaments and muscles, leading ...
Knee osteoarthritis: Current status and research progress in treatment
Kroon FPB, Carmona L, Schoones JW, Kloppenburg M. Efficacy and safety of non-pharmacological, pharmacological and surgical treatment for hand osteoarthritis: A systematic literature review informing the 2018 update of the EULAR recommendations for the management of hand osteoarthritis. RMD Open. 2018; 4 (e000734) doi: 10.1136/rmdopen-2018-000734.
Osteoarthritis: Pathology, Diagnosis, and Treatment Options
Osteoarthritis (OA) is a worldwide endemic and debilitating disease. Previously thought to simply be damaged from "wear and tear," OA is now understood to be a complex interaction of local and systemic factors. This article reviews the pathology, symptoms, diagnosis, and various conservative, surgical, and novel treatments of OA.
Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review
Importance: Osteoarthritis (OA) is the most common joint disease, affecting an estimated more than 240 million people worldwide, including an estimated more than 32 million in the US. Osteoarthritis is the most frequent reason for activity limitation in adults. This Review focuses on hip and knee OA. Observations: Osteoarthritis can involve almost any joint but typically affects the hands ...
Current understanding of osteoarthritis pathogenesis and relevant new
Osteoarthritis (OA) is the most common debilitating disease, a leading cause of disability, and is characterized by chronic pain and whole arthropathies such as articular cartilage damage ...
Osteoarthritis
Osteoarthritis is a leading cause of disability and source of societal cost in older adults. With an ageing and increasingly obese population, this syndrome is becoming even more prevalent than in previous decades. In recent years, we have gained important insights into the cause and pathogenesis of pain in osteoarthritis. The diagnosis of osteoarthritis is clinically based despite the ...
Effects of exercise on knee osteoarthritis: A systematic review
Background. Knee osteoarthritis is the most common joint disease and a major cause of functional limitation and pain in adults. The aim of this literature review is to review the existing evidence regarding the impact of exercise in people with knee osteoarthritis concerning physical and functional outcomes.
2019 American College of Rheumatology/Arthritis Foundation Guideline
Objective: To develop an evidence-based guideline for the comprehensive management of osteoarthritis (OA) as a collaboration between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of hand, hip, and knee OA. Methods: We identified clinically relevant population, intervention, comparator, outcomes questions and ...
Inflammation as a therapeutic target for osteoarthritis: A literature
The burden of osteoarthritis (OA) is rapidly increasing with population aging, but there are still no approved disease-modifying drugs available. Accumulating evidence has shown that OA is a heterogeneous disease with multiple phenotypes, and it is unlikely to respond to one-size-fits-all treatments. Inflammation is recognized as an important phenotype of OA and is associated with worse pain ...
Full article: Knee osteoarthritis: pathophysiology and current
Introduction. Osteoarthritis (OA) is the most common form of arthritis and one of the leading causes of disability. This degenerative and progressive joint disease affects around 250 million people worldwide Citation 2 and more than 27 million people in the United States. Citation 3, Citation 4 Elderly (approximately 35% of patients over 65 years old) females, patients with obesity and African ...
Osteoarthritis year in review 2019: epidemiology and therapy
Over the past year many studies and clinical trials have been published in the osteoarthritis (OA) field. This review is based on systematic literature review covering the period May 1 st, 2018 to April 19 th, 2019; the final selection of articles was subjective.Specifically those articles considered to be presenting novel insights and of potential importance for clinical practice, are discussed.
Diagnosis and treatment of hip and knee osteoarthritis: A review
A recent review provided detailed data on the utility of physical examination maneuvers in the diagnosis of hip OA, and a video demonstration of the hip examination. 30, 31 Hip internal rotation <15 degrees is moderately sensitive (66%) and specific (72%), as is limited hip adduction (80% sensitive, 81% specific). 30, 32 Pain with hip internal ...
Osteoarthritis in 2020 and beyond: a Lancet Commission
Osteoarthritis affects 7% of the global population, more than 500 million people worldwide, with women disproportionately affected by the condition.1 The number of people affected globally rose by 48% from 1990 to 2019, and in 2019 osteoarthritis was the 15th highest cause of years lived with disability (YLDs) worldwide and was responsible for 2% of the total global YLDs.1,2 Although YLDs for ...
Osteoarthritis year in review 2021: epidemiology & therapy
This "Year in review" presents a selection of research themes and individual studies from the clinical osteoarthritis (OA) field (epidemiology and therapy) and includes noteworthy descriptive, analytical-observational, and intervention studies. The electronic database search for the review was conducted in Medline, Embase and medRxiv (15th ...
The Role of Nutrition in Osteoarthritis: A Literature Review
A literature review to identify nutritional factors and the prevention and management of knee or hip osteoarthritis (OA) suggests that nutritional interventions offer some health benefits in OA through mechanisms such as weight loss, reduced inflammation, and antioxidant capacity. However, because data are limited with mixed results, high ...
Osteoarthritis: Rapid Evidence Review
Osteoarthritis (OA) is a condition commonly encountered in primary care. This article provides a brief summary and review of the best available patient-oriented evidence for OA.
Osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis in the world. It can be classified into 2 categories: primary osteoarthritis and secondary osteoarthritis. Classically, OA presents with joint pain and loss of function; however, the disease is clinically very variable and can present merely as an asymptomatic incidental finding to a devastating and permanently disabling disorder.[1][2][3]
Frontiers
Aging Neurosci., 03 May 2022. Exercise for Osteoarthritis: A Literature Review of Pathology and Mechanism. Osteoarthritis (OA) has a very high incidence worldwide and has become a very common joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug therapy, and exercise therapy.
Exercise for Osteoarthritis: A Literature Review of Pathology and
Abstract. Osteoarthritis (OA) has a very high incidence worldwide and has become a very common joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug therapy, and exercise therapy. In recent years, the treatment of certain diseases by exercise has received increasing research and attention.
Knee Osteoarthritis: A Review of Literature
Abstract. Osteoarthritis (OA) is accepted as a major public health problem. It is one. of the major causes of impaired function that reduces quality of life (QOL) worldwide. OA is a very common ...
Knee Osteoarthritis
Knee osteoarthritis (OA), also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. It is most common in the elderly. Knee osteoarthritis can be divided into two types, primary and secondary. Primary osteoarthritis is articular degeneration without any apparent underlying reason. Secondary osteoarthritis is the consequence ...
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COMMENTS
In the present paper, the pathological mechanism of exercise in OA treatment was summarized through the induction of relevant literature, as shown in Table 1. Exercise relieves the pathological changes of OA by affecting the degradation of the ECM, apoptosis, inflammatory response, autophagy, and changes of ncRNA.
Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still believed to be a mechanically driven disease, the role of underlying co-existing inflammatory processes and mediators in the onset of OA and its progression is now more appreciated. Post-traumatic ...
1. Introduction. Osteoarthritis (OA) is the most common progressive musculoskeletal condition that can affect joints, but it mainly affects the hips and knees as predominant weight-bearing joints [1,2,3].Knee osteoarthritis is characterized by structural modifications to primarily articular cartilage and the subchondral bone, but also Hoffa's fat pad, synovia, ligaments and muscles, leading ...
Kroon FPB, Carmona L, Schoones JW, Kloppenburg M. Efficacy and safety of non-pharmacological, pharmacological and surgical treatment for hand osteoarthritis: A systematic literature review informing the 2018 update of the EULAR recommendations for the management of hand osteoarthritis. RMD Open. 2018; 4 (e000734) doi: 10.1136/rmdopen-2018-000734.
Osteoarthritis (OA) is a worldwide endemic and debilitating disease. Previously thought to simply be damaged from "wear and tear," OA is now understood to be a complex interaction of local and systemic factors. This article reviews the pathology, symptoms, diagnosis, and various conservative, surgical, and novel treatments of OA.
Importance: Osteoarthritis (OA) is the most common joint disease, affecting an estimated more than 240 million people worldwide, including an estimated more than 32 million in the US. Osteoarthritis is the most frequent reason for activity limitation in adults. This Review focuses on hip and knee OA. Observations: Osteoarthritis can involve almost any joint but typically affects the hands ...
Osteoarthritis (OA) is the most common debilitating disease, a leading cause of disability, and is characterized by chronic pain and whole arthropathies such as articular cartilage damage ...
Osteoarthritis is a leading cause of disability and source of societal cost in older adults. With an ageing and increasingly obese population, this syndrome is becoming even more prevalent than in previous decades. In recent years, we have gained important insights into the cause and pathogenesis of pain in osteoarthritis. The diagnosis of osteoarthritis is clinically based despite the ...
Background. Knee osteoarthritis is the most common joint disease and a major cause of functional limitation and pain in adults. The aim of this literature review is to review the existing evidence regarding the impact of exercise in people with knee osteoarthritis concerning physical and functional outcomes.
Objective: To develop an evidence-based guideline for the comprehensive management of osteoarthritis (OA) as a collaboration between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of hand, hip, and knee OA. Methods: We identified clinically relevant population, intervention, comparator, outcomes questions and ...
The burden of osteoarthritis (OA) is rapidly increasing with population aging, but there are still no approved disease-modifying drugs available. Accumulating evidence has shown that OA is a heterogeneous disease with multiple phenotypes, and it is unlikely to respond to one-size-fits-all treatments. Inflammation is recognized as an important phenotype of OA and is associated with worse pain ...
Introduction. Osteoarthritis (OA) is the most common form of arthritis and one of the leading causes of disability. This degenerative and progressive joint disease affects around 250 million people worldwide Citation 2 and more than 27 million people in the United States. Citation 3, Citation 4 Elderly (approximately 35% of patients over 65 years old) females, patients with obesity and African ...
Over the past year many studies and clinical trials have been published in the osteoarthritis (OA) field. This review is based on systematic literature review covering the period May 1 st, 2018 to April 19 th, 2019; the final selection of articles was subjective.Specifically those articles considered to be presenting novel insights and of potential importance for clinical practice, are discussed.
A recent review provided detailed data on the utility of physical examination maneuvers in the diagnosis of hip OA, and a video demonstration of the hip examination. 30, 31 Hip internal rotation <15 degrees is moderately sensitive (66%) and specific (72%), as is limited hip adduction (80% sensitive, 81% specific). 30, 32 Pain with hip internal ...
Osteoarthritis affects 7% of the global population, more than 500 million people worldwide, with women disproportionately affected by the condition.1 The number of people affected globally rose by 48% from 1990 to 2019, and in 2019 osteoarthritis was the 15th highest cause of years lived with disability (YLDs) worldwide and was responsible for 2% of the total global YLDs.1,2 Although YLDs for ...
This "Year in review" presents a selection of research themes and individual studies from the clinical osteoarthritis (OA) field (epidemiology and therapy) and includes noteworthy descriptive, analytical-observational, and intervention studies. The electronic database search for the review was conducted in Medline, Embase and medRxiv (15th ...
A literature review to identify nutritional factors and the prevention and management of knee or hip osteoarthritis (OA) suggests that nutritional interventions offer some health benefits in OA through mechanisms such as weight loss, reduced inflammation, and antioxidant capacity. However, because data are limited with mixed results, high ...
Osteoarthritis (OA) is a condition commonly encountered in primary care. This article provides a brief summary and review of the best available patient-oriented evidence for OA.
Osteoarthritis (OA) is the most common form of arthritis in the world. It can be classified into 2 categories: primary osteoarthritis and secondary osteoarthritis. Classically, OA presents with joint pain and loss of function; however, the disease is clinically very variable and can present merely as an asymptomatic incidental finding to a devastating and permanently disabling disorder.[1][2][3]
Aging Neurosci., 03 May 2022. Exercise for Osteoarthritis: A Literature Review of Pathology and Mechanism. Osteoarthritis (OA) has a very high incidence worldwide and has become a very common joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug therapy, and exercise therapy.
Abstract. Osteoarthritis (OA) has a very high incidence worldwide and has become a very common joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug therapy, and exercise therapy. In recent years, the treatment of certain diseases by exercise has received increasing research and attention.
Abstract. Osteoarthritis (OA) is accepted as a major public health problem. It is one. of the major causes of impaired function that reduces quality of life (QOL) worldwide. OA is a very common ...
Knee osteoarthritis (OA), also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. It is most common in the elderly. Knee osteoarthritis can be divided into two types, primary and secondary. Primary osteoarthritis is articular degeneration without any apparent underlying reason. Secondary osteoarthritis is the consequence ...