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25 Best Free Leadership PowerPoint PPT Presentation Templates to Download 2024

As a business leader, it's pretty certain you're going to have to do a leadership PowerPoint presentation. In fact, you'll probably have to present regularly. Presenting effectively is a must-have leadership skill. So, it's important to learn how to make your presentations compelling. 

One key aspect of that is the visual design of your slides. Of course, not everyone's a whiz at designing presentation slides from scratch, but luckily, you don't have to be. Using premium PowerPoint templates for a leadership presentation is a good way to make sure that your presentation is professional.

In this guide, I'll share some of the best leadership PowerPoint templates , paid and free, to help you get—and keep—your audience's attention.

Best Premium PowerPoint Templates for Leadership Presentations on Envato Elements (With Unlimited Use)

If you're looking for premium leadership PowerPoint presentation templates to help you impress your audience, Envato Elements has a great offer you won't want to miss. Download as many premium leadership presentation PPT slides as you want, all for one low price.   

Here are some of the benefits of using premium leadership PPT templates for your presentations. 

First, a professional design can give your presentations that wow factor that makes your audience sit up and take notice. That's precisely the effect you want to achieve when presenting. 

And don't underestimate the impact of the professional design you'll get. It'll help your presentation look coherent . Plus, using professional leadership PowerPoint templates can save you time. That's useful if you've got a lot of presentations to create, or if slide design isn't your favorite task. 

So, it's a good idea to check out the premium leadership PowerPoint presentation templates on Envato Elements. Here's how you find them. 

Visit Envato Elements and select Presentation Templates next to the search box. Type leadership into the search box. You'll have dozens of premium leadership PowerPoint templates to choose from. Check out the previews till you find the one you want. 

When you've found a template select it, click Download , and start customizing. I'll share some tips on customizing a leadership PowerPoint presentation later in this guide. 

Envato Elements is a great choice if you're creating leadership PPT presentations regularly. But if you want leadership presentation PPT slides for one-off use, check out the PowerPoint templates for leadership presentations available from GraphicRiver.

5 Great Premium Leadership PowerPoint Templates from Envato Elements and GraphicRiver

To help you get started, here are some attractive premium  leadership PowerPoint presentation templates from Envato Elements and GraphicRiver: 

1. MOUVE - Elegant PowerPoint Template

Mouve is a minimalist, professional leadership PPT template. It'll help you communicate your points clearly and effectively. It includes 50 different slides as well as icons for customization. Plus, it's easy to edit. 

2. Speaker Up - Google Slides Template

Sometimes simple PowerPoint templates for leadership presentations work the best. At other times you want variety. SpeakerUp has three color schemes, 12 variations and 360 different slides in total. This professional theme is easy to edit and can be used in both Google Slides and PowerPoint. 

3. Balance - PowerPoint Template

If you're looking for examples of PowerPoint presentations on leadership, Balance is a full-featured starting point. Fully editable, and including icons and mockups, this leadership PowerPoint theme included more than 145 slides. 

4. Leadership

This collection of leadership presentation PPT slides will get your presentation off to a great start. It's easy to change fonts, themes, and colors to customize your presentation just the way you like it. All elements are simple to edit via the drag and drop interface.

5. Dinamika – Creative Business PowerPoint Template

Dinamika is a colorful leadership PPT template set. It includes 36 slides with customizable and resizeable graphics. This is an excellent choice for a creative presentation with lots of images. 

25 Top Free Leadership PowerPoint PPT Templates to Download for 2024 Presentations

There's no doubt that premium leadership presentation PPT slides offer an advantage in terms of design and flexibility. Plus, they save you time because you don't have to worry about fiddly design details.

But before you look for free leadership PowerPoint templates on the web, check out Envato Elements' freebies first. You'll get to try out free PowerPoint presentations on leadership while benefiting from premium design. 

Here's how it works:

• Every month Envato Elements offers 12 different hand-selected files, (fonts, presentations, videos, and more). Create a free account to download this month's free premium files now. 
• Or try Envato Market for free. They offer seven handpicked monthly freebies. Log in with your Envato Market account to get this month's handpicked premium freebies . 

But if your budget is tight, sometimes free leadership templates for presentations are what you can manage. To help you out, we've found some great leadership PowerPoint templates free to download on the web:

1. Bright Business Presentation

This is one of many free leadership PowerPoint templates on the Microsoft Office site. It's got a simple and businesslike design. 

2. Academic Presentation

This is another free leadership PowerPoint template from Microsoft. Though it's got an academic theme, the elegant design will work well in leadership settings.

3. Green Pitch Deck

If you need to make a pitch, this useful theme is another of the leadership PowerPoint templates free to download. It's an attractive way to showcase company information. Change the color scheme if necessary.

4. Training Presentation

This leadership PowerPoint template has a simple design and includes 14 slides. This is a good starting point for a leadership training presentation. 

5. Employee Training Presentation

This free leadership PowerPoint theme is suitable if you want to keep your presentation short and sweet. It's got just nine slides and is set up for delivering training courses.

6. Marshmallow

Looking for some inspiration for free? Presentations on leadership using templates are also an option. Marshmallow has a cool color scheme that's sure to appeal to your audience. 

7. Business Plan Presentation Template

This leadership PPT template is available in an attractive, muted color scheme. It'll give your presentations a professional look. 

8. Corporate Free PowerPoint

Here are templates for free PowerPoint presentations on leadership. This modern design is easy to edit, includes vector graphics, and has 10 slides. 

9. Business Consulting

Business Consulting is a free leadership PowerPoint theme. It uses a businesslike blue, white and black color scheme to create attractive slides. 

10. Business Company

This is one of several leadership PowerPoint templates free to download. It includes 16 easy to edit slides and has an understated color scheme. 

11. Investor Pro

When choosing PowerPoint templates for leadership presentation sometimes it can help to match it to your intended use. This theme is intended for investor presentations. It includes 16 relevant slide designs. 

12. Free Annual Report PowerPoint Template

If you're looking to create an annual report quickly (we've got annual report tips, too), then check out this free leadership PPT template. It includes 16 attractive slides. 

13. ProjectX Free Business PowerPoint Template

Here's another of many leadership PowerPoint templates that are free to download. ProjectX has a simple, attractive design suitable for many uses. It includes 16 slides.  

14. Free Corporate PowerPoint Template

Looking for more free PowerPoint presentations on leadership? This one has a muted color scheme and includes slides relating to common business topics. 

15. Free Corporate Company Presentation Template

Here's another of the free leadership templates. The slide set includes templates for quotes, financials and more.

16. Free Business Presentation Template

This blue-grey presentation template is suitable for a wide range of presentations. It's preset with the basic slides you need and will also work in Google Slides. 

17. Free Go-To-Market Strategy PowerPoint Template

For examples of PowerPoint presentations on leadership, check out this go-to-market template. It gives you an outline of what you need for this kind of presentation. It's also free.

18. Start Up Corporation PowerPoint Template

Launching a startup? Then this is a great template to use for a leadership presentation. It's minimalist yet colorful and will get attention.

19. Business Pitch Deck PowerPoint Template

This pitch deck template has an attractive and unusual design. It's a great example of a PowerPoint presentation on leadership for you to follow.

20. Investor Business PowerPoint Template

This leadership presentation PPT template uses serif fonts to achieve a crisp and formal look. At the same time, the minimalist design keeps it looking modern and attractive.

21. Cute Confetti

If fun is one of your leadership qualities, this PPT download is the way to go. The mixture of confetti and pastel keeps it cheerful.

22. Concentric Blue

This PowerPoint theme has a modern design and blue color scheme. It includes 25 slides, as well as icons and a world map.

23. Medical Illustrated

Here's a different kind of free leadership PPT presentation theme. This one is intended for medical presentations and the slides include relevant illustrations. 

24. Bassett

This is a well-designed theme for your next leadership PowerPoint presentation. It includes a variety of slide designs. Edit it using either PowerPoint or Google Slides. 

This is a professional theme, perfect for your next leadership presentation. It includes a range of slide designs. Edit it in either PowerPoint or Google Slides.

How to Quickly Make Great Leadership PowerPoint Presentations

Once you've downloaded your free leadership templates, the next step is to customize them to meet your needs. Here are some tips to get you started. I'll be using the premium  Hexagon PowerPoint template . 

Let's get started:

1. Edit Your Slide Title and Subtitles

I'm going to use the title slide for this. Open the presentation and go to the title slide. Double-click to select the slide title and replace it with your chosen text. Follow the same procedure to edit subtitles.

2. Add Text to Slides

Use a similar procedure to edit body text. Double-click within a text box to select all the text, then replace it by typing your own. You can also paste in pre-prepared text. 

3. Add or Resize Images

Click the onscreen image placeholder to import an image from your computer. You can also resize any image by grabbing the handles of the image placeholder and dragging them till you get the size you want.

4. Remove Unwanted Elements

On any slide, click to select an image or text box you want to remove. Then use the Delete key on your keyboard to remove it. 

5. Remove Extra Slides

At the end of the customization process, there may be a few slides you don't need. Select these in PowerPoint's slide navigator and use the Cut command to remove them.

5 Tips for a More Effective Leadership Presentation

You need your leadership PPT to engage your audience. Here are some tips to help you create a great leadership presentation:

1. Use Minimal Design

When making your leadership PPT presentation it's important to keep the information on slide minimal. You want your audience to focus on you and not be reading the slide. Having a minimal design also works because the design doesn’t make the slide overcrowded. An overcrowded slide can cause the audience to be distracted.

2. Choose the Right Font

Using the right font in your leadership PPT is important. You want the font to match the theme of your leadership PPT. You also need your font to be easily read by everyone who may see your presentation. Some fancy fonts can be hard to read.

To learn more about which fonts work well in presentations, study this tutorial:

3. Use Infographics and Graphs

Infographics are a great tool to use in your leadership presentation. Infographics use graphics to show data and other information. Infographics are also a great way to engage your audience and help them to retain information. 

4. Align Your Objects

Whether you’re creating your own leadership presentation or customizing a template, make sure objects and text are aligned. If text and objects aren’t aligned, it can look unprofessional and sloppy.

This tutorial will show you how to align objects:

5. Use High Quality Visuals

There are many types of visuals such as:

• infographics

If you've got these elements in your leadership PPT it's important that that they're high quality. If your visuals are low quality, it can look unprofessional or like you don't care.

Envato Elements is a good source for high quality images and infographics . They also have video templates that you can customize and add to your presentation. 

5 Leadership Presentation Design Trends for 2024

If you're giving a leadership PPT presentation, you want it to be up to date. A boring and dated look could make a bad impression.

Here are some popular leadership presentation design trends:

1. Muted Colors

Previously bright vibrant colors were on trend, but now muted colors are taking over. Muted colors are more calming and give an authentic and natural feel. Muted colors work well with both light and dark font making it easier to design your slides.

2. Geometric Shapes

Geometric shapes in the design of leadership presentations is the newest trend. Geometric shapes give a nostalgic and retro feel to your presentation. Geometric shapes also make fun and unique backgrounds.

 3. Animated Slides

Animated slides keeps your audience’s attention on your leadership presentation. Adding animation to a slide can make information and that slide more exciting. Animated slides are impressive and will impress your audience.

4. Alternate Between Color Slides and White Slides

Alternating colors on the slides keeps them visually interesting for the audience. You could use your company brand colors and alternate between them to reenforce your brand recognition. The color change between slides could also signal a topic change in your presentation.

5. Gradient Colors

A gradient color pattern is where one color gradually fades into another color. Gradient colors are a great way to add interest to your slides without going over the top. Gradient colors can be used as the background of your slides or for  objects on the slide.

Discover More Awesome Microsoft PowerPoint Template Designs

We've shared some attractive templates with you, paid and free. To see even more, check out the articles below:

Learn More About Making Great PowerPoint Presentations in 2024

To learn more about creating leadership PowerPoint presentations, read our in-depth PowerPoint tutorial guide. Or check out the tutorials below:

Common Microsoft PowerPoint Questions Answered (FAQs)

Whether you're just starting with Microsoft PowerPoint or have been using it a while, it's normal to have some questions. Here are common questions answered about Microsoft PowerPoint:

1. What's the Difference Between Object Animations and Animated Transitions?

Object animations are objects such as text or shapes going in motion on a slide. Animated transitions are animations that play when you move from one side to the next. To learn how to add animation to your leadership slides in PowerPoint, study this tutorial: 

2. Can I Reduce My PowerPoint File Size?

Do you need to send your leadership PPT presentation to your coworkers but are worried that it won’t fit in an email? Don’t worry. You can reduce the file size. For information about how to reduce your PowerPoint file size down check out this tutorial: 

3. How Do I Share a Leadership PPT Presentation in a Zoom meeting?

Figuring out a new software or learning how to use the software in a new way can be tricky. These days, learning how to give a presentation over Zoom is really useful knowledge to have. Here's a tutorial to help you out: 

4. How Do I Make a Chart or Graph for My Leadership PPT?

Charts and graphs can be great tools to show data in your presentation. Seeing charts and graphs engages your audience more than a list of numbers. Here's a tutorial on how to make charts and graphs in PowerPoint: 

5. How Do I Make the Leadership Slides in my PowerPoint More Interesting?

Having a boring leadership PPT presentation can mean that your presentation is forgettable. Interesting slides keep your audience engaged throughout your presentation. And they make it more memorable. Here are some tips on how to make your presentation design more interesting: 

Create Your Next Leadership PowerPoint Presentation Today

You've seen some appealing PowerPoint templates for leadership presentations, including some free leadership PowerPoint templates. As you decide which templates to use, remember that premium templates offer some advantages over free templates on the web. 

Check out the leadership PowerPoint templates available from Envato Elements. You can also try leadership PowerPoint templates on GraphicRiver. It offers dozens of leadership presentation PPT slides for you to try. 

Why not create your leadership PowerPoint presentation today? Download your favorite leadership PPT template and get started.

Editorial Note : This post has been updated with contributions from Sarah Joy . Sarah is a freelance instructor for Envato Tuts+.

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10 Presentation Ideas For Leadership Teams and Training

Leadership teams shape organizations for better or for worse. They’re responsible for guiding teams and moving things— big or small— forward. So what makes a great leader versus one that causes employees to leave a company?

When you think of a great leader, it’s probably a specific characteristic that comes to mind. Qualities like respect, self-awareness, trust, influence, collaboration, and strong communication skills can set extraordinary managers apart from mediocre ones. But how leaders listen, learn, and communicate with their employees is just as important. Because of that, leaders— regardless of the industry— need to hold themselves accountable and continuously seek out ways to grow as a manager.   

It’s not uncommon for companies to host offsites or retreats to bring the leadership team together for brainstorming, planning, and training. This helps align leaders across various departments, teams, and offices, while offering them the tools they need to be more successful in their role. 

When preparing a presentation for leadership teams and training, it's crucial to focus on content that resonates with the audience's strategic mindset and their role in guiding the organization. Here are some leadership presentation ideas to help inspire your own content.

Leadership presentation ideas

Presentations can act as a platform to encourage learning and collaboration among different leaders. Do you have a leadership retreat coming up? Here are 10 leadership presentation ideas to help train and motivate your own leadership team. 

Effective leadership strategies

As a recurring training, you might share effective leadership strategies with your executive team. This presentation would act as a refresher of the latest trends and best practices in leadership. This could include insights on empathetic leadership, fostering a positive company culture, and embracing diversity and inclusion.

Change management

How should managers and leadership teams address the challenges and opportunities associated with change within the organization? A change management presentation would provide strategies for how leaders can navigate transitions successfully, with the least amount of disruption to the team.

Strategic planning and decision-making

A strategic planning and decision making presentation will offer insights into the process of setting achievable goals and making informed decisions. Organizations might also use a strategic planning presentation to lead their own company brainstorming sessions at a leadership all-hands meeting. 

Team development and engagement

Team development and engagement is important for the overall success of the team. In this presentation you might share techniques for fostering a high-performing and engaged team, including methods for providing feedback, coaching, and creating a supportive work environment.

Communication skills

Communication skills can make or break a leader. A training session on effective communication in leadership roles could be beneficial for both managers and executives of all levels. Here you could offer practical tips for clear, transparent, and empowering communication.

Leading through uncertainty

Given the current business landscape and layoffs happening across various industries, leadership teams need to know how to handle hard situations. This presentation idea for leadership teams would discuss strategies for navigating uncertainty and ambiguity, including how to maintain resilience and inspire confidence in a team concerned about job security. 

Embracing innovation and creativity

It’s no secret that AI is here to stay, and teams are having to pivot to accommodate new technology. Use a thoughtful presentation to encourage leaders to embrace innovation and promote a culture of creativity within the organization. The slides in this deck could showcase the benefits of adopting innovative approaches and thinking outside the box.

Building high-performance teams

Leaders need the right tools and knowledge to be able to guide positive performance. Employers might offer a training “how-to” on best practices for assembling and nurturing high-performance teams. This deck should include strategies for fostering collaboration, trust, and accountability among teammates. 

Data-driven decision making

As a leader, leveraging data to make more informed decisions should be top of mind. This leadership presentation idea can highlight the importance of leveraging data and analytics in decision-making processes, and offer guidance on how to incorporate data-driven insights into leadership strategies. This could include ways to implement KPIs, OKRs, or other effective ways to track the performance of individual contributors and campaigns. 

Ethical leadership

A wildly important leadership topic is ethics. Upper management should be well-educated in ethical leadership, and how that impacts the success of the team. An ethical leadership presentation could include the significance of ethics, the impact it has on organizational culture, employee morale, and long-term success, and how to ensure it’s top of mind in each department on a daily basis.

Beautiful presentations to drive your message home

You have a presentation topic, now what? The hardest part of presentation design is going from idea to deck with little design skills to back you up. Thankfully, there's a presentation software for that. Insert: Beautiful.ai. Beautiful.ai helps leadership teams create beautiful presentations so they can pack a bigger punch with their message and inspire their audience. Presenters can use one of Beautiful.ai's customizable pre-built presentation templates — like the training presentation — or leverage our AI-assistant to create a presentation from scratch specific to their topic. By creating beautiful decks you can engage your audience, drive your message home, and leave your leadership team feeling inspired to make a difference.

Jordan Turner

Jordan is a Bay Area writer, social media manager, and content strategist.

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Leadership PowerPoint Presentation

Number of slides: 10

Every business needs good leaders that motivate people to act towards the same goals. A leadership training program is a great option if you want to prepare professionals for key roles inside the company or to make your staff develop valuable skills. In this corporate template, you will be able to cover what leadership means for the company, the skills of a good leader, the difference between a manager and a leader, and more.

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Free Leadership Training Presentation Slides

Leadership overview slide.

First things first, what is leadership? You can find countless definitions, but it’s important that you explain what leadership means for the company. In this slide, you will be able to present your own definition of a good leader and sum up key ideas.

Leadership Skills Slide

Every leader has a unique set of traits and skills. Here you will be able to address the latter in a highly visual doughnut chart. Some examples of leadership skills are awareness, communication, integrity, accountability, and vision. Add the ones you fit to the kind of leader you want to have in your company.

Leadership vs Management Slide

Manager is someone with authority over a team. This person is in charge of managing a group of people and supervising their tasks. However, being a manager doesn’t always equals being a leader. Leaders don’t need to hold a key position to drive a team. In this slide, you’ll be able to discuss the difference between a leader and a manager and how to get to the best scenario: a manager with strong leadership skills.

Corporate style template

The blue corporate style of the Leadership PowerPoint template fits any type of business.

Agenda slide

This template comes with a corporate agenda slide to list the sessions and key information of the leadership training program.

Leadership styles

When it comes to leadership, there’s no just one style that fits all. Your company needs to identify what kind of leader each team requires according to their strengths and weaknesses.

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11 Leadership Presentation Ideas for Team Training

• By Judhajit Sen
• May 21, 2024

Leadership development topics equip aspiring leaders with the skills and tactics necessary for effective management. These topics for leadership presentations help leaders understand their roles and view challenges as opportunities for growth. Training provides insights into team expectations and highlights critical aspects that drive productivity and efficiency within the company. Moreover, comprehensive management training builds confidence, helping leaders excel in their roles and identify areas for improvement and growth.

Leadership roles are pivotal in shaping organizations. Great leaders possess qualities such as respect, self-awareness, trust, influence, collaboration, and strong communication skills. They are distinguished by their ability to listen, learn, and communicate effectively with their teams. Accountability and a continuous pursuit of growth are essential traits for leaders in any industry. Hosting offsites or retreats for leadership teams can facilitate brainstorming, planning, and training, aligning leaders across departments and providing the tools necessary for success.

Leadership meetings gather vital decision-makers to discuss, strategize, and make critical decisions shaping the company’s future. These meetings are essential for sharing insights, setting goals, and aligning efforts towards a shared vision. Effective communication during these presentations ensures alignment, inspiration, informed decision-making, accountability, and innovation. By focusing on these elements, leadership slide presentations can resonate with the audience’s strategic mindset and their pivotal role in guiding the organization.

Following are 11 leadership presentation ideas for team training.

Key Takeaways

• Leadership training equips leaders with essential management skills, helping them understand their roles and view challenges as growth opportunities.
• Effective leaders possess qualities like respect, self-awareness, trust, and strong communication skills, fostering a positive work environment.
• Leadership meetings are vital for decision-making, goal setting, and aligning efforts toward a shared vision.
• Mastering soft skills, time management, and understanding different leadership styles are crucial for successful team leadership and organizational growth.

Mastering Communication: A Must-Have Skill for Leaders

Effective communication is crucial for any leader. It’s more than just talking—it’s about sharing ideas, giving directions, and understanding your team. This leadership slides idea should be at the top of your workshop agenda.

Here’s why communication skills matter:

Clarity in Ideas: Leaders must present their thoughts in a way everyone understands. Clear communication prevents confusion and ensures everyone is on the same page.

Active Listening: Good leaders don’t just talk; they listen. By genuinely hearing team members’ concerns and feedback, leaders can better address issues and foster an environment of trust.

Empowerment Through Words: Leaders should use their words to empower their teams. Transparent and encouraging communication boosts morale and drives productivity.

Training in these skills can significantly benefit managers and executives. Offer practical tips and exercises to help them communicate more effectively. When leaders master these skills, they build stronger, more loyal teams, paving the way for business plan success.

Navigating Leadership Challenges: Building Resilience and Conflict Resolution Skills

Leading isn’t easy—it comes with its fair share of challenges. Here’s why addressing these challenges should be a priority for your leadership PowerPoint – 

Leading Under Pressure: Leaders face stress and pressure daily. Equip them with strategies to handle crises and high-pressure situations effectively. Developing mental and emotional strength is crucial for overcoming challenges.

Navigating Uncertainty: Uncertainty is common in today’s business landscape, especially with layoffs and economic changes. Leaders must maintain resilience and inspire team confidence during tough times.

Managing Difficult Situations: It is vital to discuss challenging topics like handling problem employees, delivering bad news, or leading initiatives you disagree with. These discussions can lead to growth and provide valuable insights for all leaders.

Managing Emotions: Leaders must also effectively manage their own emotions. Topics like staying humble, overcoming fear, and avoiding burnout are often overlooked but essential for long-term success. Encouraging open discussions about personal struggles is vital to supporting leaders’ well-being.

Resolving Conflict: Conflict is unavoidable in any workplace. Teach leaders how to resolve conflicts constructively. By mastering interpersonal skills, leaders can turn conflicts into opportunities for growth and strengthen team relationships.

By addressing these challenges head-on and providing practical training, you can empower leaders to navigate challenging situations and confidently lead their teams to success.

Maximizing Team Engagement: Key Strategies for Effective Leadership

Employee engagement isn’t just a buzzword; it’s a critical aspect of effective leadership. Keeping your team motivated and committed ensures they perform at their best and stay with the organization longer. This leadership training PowerPoint slides idea delves into the essential elements of team engagement and provides actionable strategies for leaders to implement.

Prioritizing Engagement: Leaders must recognize the importance of keeping their teams engaged. Engaged employees are happier and contribute more effectively to organizational goals. By prioritizing engagement, leaders foster a positive work environment where the team feels valued and motivated.

Strategies for Engagement: Consistent engagement requires deliberate effort. Leaders can benefit from learning and implementing various methods to engage their teams. From recognizing achievements to fostering open communication, there are numerous tactics leaders can employ to stimulate engagement and boost team morale.

The Power of Feedback:  Effective feedback fosters engagement and improves performance.  Offering constructive criticism helps employees understand their strengths and areas for improvement, guiding them toward success. Leaders must learn the art of giving feedback that motivates rather than demotivates, fostering a culture of growth and development within the team.

Building a Supportive Environment:  A supportive work environment is crucial for team development and engagement.  Leaders must create a culture of collaboration, trust, and respect. They can nurture a high-performing and engaged team by providing growth opportunities and recognizing individual contributions. Start already with the hiring process. Include opening of paid training positions, like ones you can check on Jooble . Invest in education of your employees from the very beginning to get the best results in future.

Continuous Learning and Development: Engaging teams isn’t a one-time effort; it requires constant learning and development. Leaders should invest in ongoing training programs to enhance their skills in fostering engagement, providing feedback, and nurturing team dynamics. By continuously improving their leadership abilities, leaders can create a culture of engagement that drives organizational success.

Maximizing team engagement is a vital aspect of effective leadership. Leaders can cultivate high-performing teams that drive organizational success by prioritizing engagement, implementing strategic approaches, and fostering a supportive environment.

Mastering Soft Skills: Empowering Leaders for Success

Effective leadership goes beyond hiring top talent; it requires the ability to inspire and guide teams toward success. This leadership PowerPoint presentation idea explores the significance of soft leadership skills and offers valuable insights for enhancing these skills among team leaders and managers.

The Power of Influence:  Good leaders can motivate and influence their teams. By understanding different motivational techniques and strategies, leaders can foster a culture of enthusiasm and productivity within their teams. From recognizing individual achievements to cultivating a “can-do” attitude, influential leaders inspire their teams to achieve greatness.

Understanding Soft Skills:  Soft skills are personal traits that allow us to interact effectively with others. In today’s dynamic workforce, soft skills foster collaboration, communication, and teamwork. From communication and problem-solving to leadership and adaptability, mastering soft skills is essential for success in the modern workplace.

Building Strong Foundations:  Soft skills encompass a broad spectrum of attributes, each contributing to effective leadership. These skills form the foundation of successful leadership, from communication to critical thinking and stress management. By developing these skills, leaders can enhance their ability to connect with their teams and drive positive outcomes.

Continuous Improvement:  Soft skills are not innate; they can be developed and honed over time. Leaders should embrace opportunities for continuous learning and skill development. By investing in training programs and workshops focused on soft skills development, leaders can strengthen their ability to lead and motivate their teams to excel.

Turning Theory into Action:  While understanding the importance of soft skills is crucial, putting theory into practice is equally essential. Leaders should actively apply soft skills in their daily team interactions, fostering open communication, collaboration, and mutual respect. Through their actions, leaders can empower their teams to thrive.

Mastering soft skills is essential for effective leadership. By understanding the power of influence, embracing a wide range of soft skills, and continuously striving for improvement, leaders can empower their teams to achieve success and drive organizational growth.

Mastering Time Management: Empowering Leaders for Success

Time management is an invaluable aspect of effective leadership that training managers should prioritize. This presentation idea highlights the importance of time management for leaders and provides valuable insights for improving this essential skill.

Working Smarter, Not Harder:  Leaders often juggle multiple responsibilities, making time management indispensable. Leaders can learn to prioritize tasks, allocate time efficiently, and optimize productivity by focusing on this training topic. The goal is to help leaders work smarter, not harder, by enhancing their management skills and achieving maximum effectiveness.

Quality Over Quantity:  Overworking should never be the standard for good work. Effective time management enables leaders to produce sustainable, high-quality results in less time. By mastering time management, leaders can make better decisions, maintain consistency, and positively impact their team members’ performance.

The Power of Delegation:  Delegation is a core function of leadership and a vital time management skill. Leaders must learn to assign tasks to the right people and trust them to deliver quality results. Proper delegation saves time and fosters engagement among team members, inspiring them to put forth more effort and commitment.

Fostering Engagement: Delegation, coupled with effective time management, fosters engagement within teams. When leaders delegate tasks efficiently, they empower their team members and enable them to take ownership of their work. This responsibility motivates team members to perform at their best, driving overall productivity and success.

Maximizing Impact: As John C. Maxwell aptly stated, “If you want to do great things and make a big impact, learn to delegate.” Effective time management and delegation allow leaders to focus on high-impact tasks that drive organizational growth and success. By mastering these skills, leaders can elevate their effectiveness and make a lasting impact on their teams and organizations.

Mastering time management is essential for effective leadership. Leaders can maximize their impact and drive success in their organizations by working smarter, delegating tasks effectively, and fostering engagement within teams.

Exploring Leadership Styles: Empowering New Leaders

Understanding different leadership styles is essential for new and aspiring leaders. This presentation idea highlights the importance of exploring various leadership styles and offers valuable insights for leadership training and development.

Empowering New Leaders: Leadership training for new leaders should include exploring different leadership styles. By clearly understanding various approaches, leaders can develop their own leadership style and identify opportunities for improvement. This training creates a foundation for effective leadership and empowers leaders to lead their teams confidently.

Daniel Goleman’s Six Styles:  Developed by Daniel Goleman, the six leadership styles offer valuable insights into situational leadership. Each style addresses different needs and situations, allowing leaders to adapt their approach accordingly. From visionary to commanding, each style has its unique strengths and applications.

Tailoring Leadership to Situations: Effective leadership requires adapting to various situations and individuals. By understanding the six leadership styles, leaders can assess their team’s needs and choose the most appropriate style for the problem. Whether mobilizing people toward a vision or demanding immediate compliance, leaders can tailor their approach for maximum effectiveness.

Building Versatility: Exploring different leadership styles allows new leaders to develop versatility in their approach. By combining elements of various styles, leaders can create a personalized style that aligns with their strengths and the needs of their team. This versatility enables leaders to navigate diverse challenges and drive positive outcomes.

Continuous Learning and Improvement:  Leadership is a journey of constant learning and improvement. New leaders should embrace opportunities to explore and refine their leadership styles over time. Leaders can become effective and impactful by seeking feedback and experimenting with different approaches.

Exploring different leadership styles is essential for new leaders’ development. By understanding the six styles, tailoring leadership to situations, building versatility, and embracing continuous learning, new leaders can cultivate their leadership skills and positively impact their teams and organizations.

Embracing Diversity & Inclusion: Essential Leadership Training

Diversity and inclusion are vital aspects of effective leadership in today’s global market. This presentation idea emphasizes the importance of fostering diversity and inclusion within teams and offers valuable insights for leadership training and development.

Leading a Diverse Team:  In today’s diverse workforce, leaders must know how to collaborate with individuals from various backgrounds, cultures, and identities. Embracing diversity means bringing together the unique qualities of each team member to work in harmony. Leaders play an important role in ensuring that all team members are equally heard, seen, and recognized for their contributions, regardless of their differences.

Combatting Stereotypes and Bias:  Raising awareness about diversity and inclusion helps leaders combat stereotypes, discrimination, and unconscious bias within their teams. By fostering inclusivity, leaders  create a safe workspace  where team members  feel valued and respected.  This enhances team morale and promotes creativity, innovation, and productivity.

Effective Leadership Strategies:  Sharing practical strategies for embracing diversity and inclusion is essential for leadership training. Leaders should focus on empathetic leadership, foster a positive company culture, and create opportunities for diverse voices to be heard. By embracing diversity and inclusion, leaders can build stronger, more resilient teams that drive organizational success.

Situational Leadership: Situational leadership is paramount in today’s workforce. With a diverse employee base, leaders must recognize that one size does not fit all. Understanding when and how to use different leadership styles with different individuals and situations is critical for success. Leaders should develop scenarios relevant to their teams and encourage discussion on how they would approach each situation differently based on individual needs and circumstances.

Embracing diversity and inclusion is essential for effective leadership. Leaders can create diverse, high-performing teams that drive organizational success by fostering a culture of inclusivity, combatting stereotypes and bias, and embracing effective leadership strategies.

Navigating Change: Essential Leadership Training

Every organization faces change, and leaders must know how to navigate it effectively. This presentation emphasizes the importance of change management in leadership training and offers valuable insights for guiding teams through transitions.

Coping with Change:  Leaders face the challenge of dealing with change, big or small. They must understand how to navigate these situations and effectively communicate with their teams. This includes dealing with new challenges, workflow disruptions, and employee feedback. With proper training, leaders can guide their teams to overcome obstacles brought about by change and maintain productivity.

Addressing Challenges and Opportunities: Change management presentations provide strategies for leaders to address the challenges and opportunities associated with organizational change. Organizations can navigate transitions smoothly by equipping leaders with the necessary tools and presentation techniques , minimizing team disruption, and maintaining business continuity.

Essential Skill for Leaders:  Managing change is a necessary skill for leaders in today’s fast-paced world. The rapid pace of change is driven by various factors like news cycles and social media, so leaders must be adept at managing transitions effectively. Books like “Leading Change” and “Our Iceberg is Melting” by John Kotter offer valuable insights into change management strategies that leaders can apply in their organizations.

Organizational Reflection:  Leaders can facilitate discussions within their teams about how they deal with change and the level of change their organization has experienced over the years. This reflection allows leaders to gain insights into their team’s resilience and adaptability and identify areas for improvement in change management processes.

Change management is an essential aspect of leadership training. By equipping leaders with the skills and strategies to navigate change effectively, organizations can ensure smooth transitions and maintain productivity during periods of change.

Mastering Decision Making: Key Leadership Training

Decision-making is an indispensable skill for effective leadership. This presentation idea explores the importance of strategic planning and informed decision-making, offering valuable insights for leadership training.

Goal Setting for Success:  Setting clear, attainable goals is fundamental for staying focused and achieving a leader’s purpose. Goals provide direction and help leaders prioritize what truly matters. For goals to be effective, they must be well-defined and achievable within a specific timeframe. This clarity ensures that leaders can measure progress and stay on track.

Strategic Planning and Decision Making:  A strategic planning presentation offers insights into setting achievable goals and making informed decisions. Leaders can use these strategies to guide company brainstorming sessions and leadership meetings, ensuring that decisions align with organizational objectives and drive success.

Data-Driven Decisions:  Leveraging data is crucial for making informed decisions. Leaders should prioritize using data and analytics to guide their decision-making processes. This includes implementing key performance indicators (KPIs), objectives and key results (OKRs), and other metrics to track performance. Data-driven insights help leaders make better choices and improve overall effectiveness.

Incorporating Data into Leadership Strategies: Effective leadership involves incorporating data-driven insights into strategies. By understanding and utilizing data, leaders can make more informed decisions that enhance team performance and organizational success. Data visualization presentations can guide how to integrate data analytics into everyday decision-making, ensuring leaders are equipped with the tools they need to succeed.

Mastering decision-making is essential for effective leadership. By setting clear goals, engaging in strategic planning, and leveraging data, leaders can make informed decisions that drive institutional success and foster a culture of continuous improvement.

Running Effective Meetings: Essential Leadership Training

Meetings are a cornerstone of company communication, but they can become unproductive without proper structure. This presentation idea focuses on strategies for managing effective meetings, offering essential insights for leadership training.

The Importance of Structure: Effective meetings require a clear objective and structure. Without these, meetings can waste time and reduce productivity. Leaders must learn to determine if a meeting is necessary, set proper leadership meeting agenda topics, and consider each team member’s strengths. By doing so, meetings can foster teamwork, accomplish goals, and boost overall productivity.

Agenda and Scheduling: A well-planned agenda is crucial for a leadership meeting. Leaders should outline key discussion points and allocate time for each topic. This ensures the meeting stays focused and covers all necessary information. Scheduling meetings conveniently for all participants also helps maintain focus and engagement.

Engagement and Focus:  It is essential to keep employees motivated and engaged during meetings. Leaders can use tips and tricks, such as interactive activities or breaks, to maintain focus. Ensuring that meetings are concise and to the point helps keep attendees’ attention and makes the meeting more productive.

Action Items:  Ending meetings with a set of action items is crucial for ensuring follow-through. Leaders should summarize the key points discussed and delegate tasks to team members with clear deadlines. This ensures accountability and helps track progress in meeting objectives.

Meeting or Email?: Not every discussion requires a meeting. Leaders should evaluate whether an email would suffice. Playing a game with attendees like “Meeting or Email?” can help illustrate this point. By providing examples and encouraging candid discussion, leaders can better discern when meetings are necessary and when other forms of communication are more efficient.

Managing effective meetings is a critical skill for leaders. Leaders can make the most of their team’s time and drive productivity by ensuring meetings have clear objectives and well-planned agendas and end with actionable tasks. This training gives leaders the tools to run productive and engaging sessions, enhancing overall organizational efficiency.

Accountability & Ethical Leadership: Building Trust and Integrity

Accountability and ethical leadership are crucial topics for effective leadership training. This presentation idea outlines the importance of these concepts and provides insights for fostering a culture of responsibility, credibility and integrity.

The Power of Accountability:  Accountability is a crucial trait of good leadership. Leaders who accept responsibility for their actions, whether positive or negative, earn the trust and respect of their employees. This trust leads to a more productive and positive work environment. Leadership training should focus on teaching behaviors that build and enhance accountability, promoting a workplace where honesty and responsibility are valued.

Cultivating Ethical Leadership:  Ethics are fundamental to successful leadership. Leaders must understand the importance of ethical behavior and its impact on organizational culture, employee morale, and long-term success. Training on ethical leadership should highlight the significance of ethics, provide strategies for maintaining high moral standards, and emphasize the need for ethical considerations in daily decision-making across all departments.

Building a Trustworthy Environment:  Organizations can create a trustworthy and reliable environment by combining accountability and ethical leadership. Leaders who embody these qualities set a positive example for their teams, fostering a culture of integrity and transparency. This environment encourages employees to act responsibly and uphold the organization’s values.

Practical Applications:  Leadership training should include practical applications of accountability and ethical leadership. This can involve case studies, role-playing scenarios, and discussions on real-life situations where leaders demonstrated these qualities. Such exercises help leaders internalize and apply these concepts in their daily roles.

Long-Term Benefits:  Emphasizing accountability and ethical leadership leads to long-term benefits for organizations. It enhances team cohesion, improves decision-making processes, and builds a strong reputation for the organization. Leaders prioritizing these values contribute to sustainable success and a positive organizational culture.

Accountability and ethical leadership are essential components of effective leadership. By focusing on these topics in leadership training, organizations can develop trusted, responsible, and committed leaders to uphold high ethical standards, driving long-term success and a positive workplace culture.

Leadership Training: Keys to Effective Management

Leadership training ideas equip aspiring leaders with essential skills and tactics for effective management. It helps them understand their roles, view challenges as opportunities, and build confidence. Great leaders, distinguished by qualities like respect and communication skills, are pivotal in shaping organizations. They listen, learn, and adapt continuously, fostering a positive work environment. Leadership meetings are crucial in decision-making and aligning efforts towards a shared vision. Effective communication during these meetings ensures alignment, inspiration, and innovation. By focusing on these ideas for leadership, different types of presentations can resonate with leaders’ strategic mindsets and their roles in guiding the organization.

Frequently Asked Questions (FAQs)

1. What skills are essential for effective leadership?  

Key skills include communication, accountability, resilience, and the ability to inspire and influence teams. Leaders should also be adept at managing emotions and resolving conflicts.

2. How can leadership training benefit aspiring leaders?  

Training equips leaders with the necessary tactics and skills, builds confidence, and helps them understand their roles and team expectations, driving productivity and efficiency.

3. What role do leadership meetings play?  

Leadership meetings gather decision-makers to strategize, set goals, and align efforts, ensuring the company’s vision is communicated and pursued effectively.

4. Why is communication important for leaders?  

Effective communication ensures clarity, fosters trust, empowers teams, and drives morale and productivity, making it a critical skill for leaders to master.

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Home Inspiring Leadership Now

30 of the best ted talks on leadership that every great leader should watch – 2nd edition.

Last updated: 4 March 2020

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Love inspiring Ted Talks on leadership? So do we!

That’s why we put together this list of our  crème de la crème TED Talks on leadership.

So next time you’re needing a little boost, take a 20-minute break to listen to one of these and learn from some of the most forward-thinking and innovative experts to discover what’s given them their little-known edge.

1.  How Great Leaders Inspire Action , by Simon Sinek

With more than 29 million views , Simon Sinek is now on the A-List of leadership gurus, after he gave this incredible talk.

As Sinek himself says, “As it turns out, all the great inspiring leaders and organizations in the world, whether it’s Apple or Martin Luther King, Jr. or the Wright brothers, they all think, act and communicate the exact same way. And it’s the complete opposite to everyone else. All I did was codify it, and it’s probably the world’s simplest idea. I call it the Golden Circle.”

For Sinek, the difference between these inspirational leaders and everyone else is they start with “why,” which is the core concept of his Golden Circle . By asking why, how and what, you can set yourself on a trajectory of tremendous success that, statistically speaking, very few people attain.

2.  The Puzzle of Motivation , by Dan Pink

To be an effective leader, you need to know what makes people “tick,” and especially what motivates them in the workplace to give you their best. Interestingly enough, money only takes you so far.

In this compelling video –which has clocked over 13 million views – Pink (author of  Drive: The Surprising Truth About What Motivates Us ) untangles the web of motivation in a way that makes sense for leaders. Here’s a hint : traditional rewards aren’t always as motivating as we think.

3.  Why We Have Too Few Women Leaders , by Sheryl Sandberg

Sandberg left Google to become Facebook’s COO in 2008. In this video, she looks at why so few women make it to the C-suite, and offers up three important pieces of advice to women who want to buck the trend and get there. The key, in Sandberg’s view, is ensuring women remain in the workforce.

As it turns out, having more women remain in the workforce has other positive benefits on society and households, such as equal earning and equal responsibility between partners. As Sandberg notes, households that demonstrate this equality also have half the divorce rate.

4.  The Difference Between Winning and Succeeding , by John Wooden

To be a successful leader, what better place to start than by defining exactly what you mean by success? The man affectionately known as “Coach” redefines success to be much more than merely winning. Coach James Wooden explains this difference with profound simplicity, and urges everyone to pursue the best in themselves. The Coach’s 17-minute talk is uplifting as much as it is inspiring.

5.  What Makes us Feel Good About Our Work ? By Dan Ariely

Dan Ariely is a behavioral economist who has gained a deeper understanding of human motivation than most economists could ever hope for. He even designed experiments that would help solve the mystery of motivation, which is what this video is all about.

As it turns out, money isn’t the only thing that motivates us to work. It isn’t exactly joy, either. The real motivation for going to work every day is to make constant progress and lead a life of purpose . Strong leaders care about the bottom line, but are about much more than that. They have a sense of purpose, and get out of bed every single day to fulfill it.

6.  Why Good Leaders Make You Feel Safe , by Simon Sinek

Simon Sinek’s material is so good that he’s the only one to appear twice on this list. You know building trust among your followers is important, but actually doing it is another thing entirely.

Sinek’s video on the topic will take your understanding of trust to a whole new level. After all, humans are emotional species who struggle with insecurities and vulnerabilities. A good leader brings his or her employees into a circle of trust. This is especially important in today’s economy, where jobs are destroyed as fast as they are created. Leaders have a responsibility to make their workers feel safe.

7.  Dare to Disagree , by Margaret Heffernan

When it comes to forming your dream team, the last thing you should do is surround yourself with what Heffernan calls “echo chambers” who only tell you what they think you want to hear. Mastering the art of disagreement is essential to effective leadership. Leaders must also be willing to cope with others disagreeing with them. Only through disagreement are ideas challenged.

Hefferman outlines a rubric for avoiding echo chambers and allowing ourselves to experience what she calls constructive conflict.

“So what does that kind of constructive conflict require? Well, first of all, it requires that we find people who are very different from ourselves. That means we have to resist the neurobiological drive, which means that we really prefer people mostly like ourselves, and it means we have to seek out people with different backgrounds, different disciplines, different ways of thinking and different experience, and find ways to engage with them. That requires a lot of patience and a lot of energy.”

8.  Lead Like The Great Conductors , by Itay Talgam

You’ve no doubt heard leadership described through the metaphor of conducting an orchestra. Itay Talgam operationalizes that metaphor by sharing what leaders can learn from 6 different 20th-century conductors. Don’t worry, this TED Talk requires no formal background (or interest) in the symphony.

Talgam describes the “magical moment” when a conductor turns chaos into blissful music. It’s a very small gesture, “not very pomp, not very sophisticated.” And suddenly, out of the chaos, noise becomes music.

9.  As Work Gets More Complex, Six Rules to Simplify , by Yves Morieux

Everyone knows that a staggering number of people are disengaged from their work. Yves Morieux argues that our reaction to the unfathomable complexity of modern work has a lot to do with that disengagement. Traditional organizational management certainly doesn’t help, either. His antidote includes 6 refreshing ways to engage in what he calls “smart simplicity.” The first rule is understand what your colleagues actually do. This is especially important for business leaders if they wish to simply the workplace and boost employee engagement.

10.  What It Takes To Be A Great Leader , by Roselinde Torres

Roselinde Torres has developed a deep understanding of what makes leaders effective. She poses 3 laser-like questions that will spur your own thinking on what it takes to be a great leader.

In a world filled with executive leadership programs and expensive seminars, Torres argues the best way to learn leadership might be right under your nose. Torres’ 9-minute talk is candid and to the point.

11.  A Life of Purpose , by Rick Warren

His book, Purpose-Driven Life, has sold more than 30 million copies. The church he pastors, Saddleback Church, has more than 22,000 members. Clearly, Rick Warren understands a few things about leadership.

This video is an intimate presentation of his own thoughts and crises around leadership. For anyone who’s ever looked at their existence and said, “There’s got to be more to life than this” will certainly find solace in Warren’s 21-minute talk.

12.  Listen, Learn… Then Lead , by Stanley McChrystal

Stanley McChrystal is a 4-star general who spent decades in the military. What he gleaned about leadership that can build a shared sense of purpose among an incredibly diverse set of followers boils down to how well you listen and learn, as well as how you position failure.

McChrystal’s view of leadership can be summarized with the following quote:

“[A] leader isn’t good because they’re right; they’re good because they’re willing to learn and to trust. This isn’t easy stuff.”

13.  Got a Wicked Problem to Solve? First, Tell me How you Make Toast , by Tom Wujec

Making toast is simple, right? But what happens when someone asks you to draw how you make toast? Suddenly things get interesting, and complicated.

This simple exercise reveals much about leading solutions to complex problems. Tom Wujec invites listeners to run the exercise themselves while explaining what he’s learned from observing thousands of people draw toast. From this talk, leaders will learn some important truths about how to handle real-world challenges .

14.  Everyday Leadership , by Drew Dudley

Drew Dudley’s whole approach is to make sure everyone understands how to bring out the leader within. Too many people think great leadership is reserved for extraordinary people.

His humorous take will remind you of all the little things leaders do each day. Leadership may be self-taught, but certainly isn’t reserved to a special segment of society. Dudley reminds us that leadership is an everyday act that should be celebrated.

15.  Tribal Leadership , by David Logan

It’s easy to think that as a species we have evolved far beyond the days of tribalism, but management consultant David Logan argues that effective leaders understand the 5 kinds of tribes that still crop up naturally in nearly any setting. Logan’s talk takes you through the 5 tribes, or stages, beginning with “Life sucks” and ending with “Life is great.”

16. Learning From Leadership’s Missing Manual , by Fields Wicker-Miurin

If you missed the opening line of this article, Fields Wicker-Miurin will remind you that leadership is self-taught. People who are looking for the holy grail leadership manual will wait forever in vain.

Leadership comes from within , but that shouldn’t stop you from developing the qualities that people admire in a great leader. Instead of looking for a how-to manual, learn the inspiring story of a local leader in your community. They’re not as far away or elusive as you might think.

17. How To Make Work-Life Balance Work , by Nigel Marsh

Leaders may be workaholics, but they also value work-life balance. That’s Nigel Marsh’s main thrust in this 2010 talk. Marsh shows you how to share a balance lifestyle between family, personal time and productivity. He also drops some inspiration from his books Fit, Fifty, and Fired Up and Overworked and Underlaid (yes, he has a great sense of humor).

Achieving an ideal work-life balance may seem like a jigsaw puzzle, but isn’t nearly as hard as our productivity-obsessed culture makes it out to be. Through small changes, you can have a big impact on work, relationships and life in general.

18. The Key To Success? Grit , by Angela Lee Duckworth

Successful consultant-turned-teacher Angela Lee Duckworth reminds us that success requires hard work and grit. While this is nothing we don’t know, why are these characteristics so difficult to apply? As Duckworth says, “as much as talent counts, effort counts twice.”

Duckworth’s quick talk is an essential listen for anyone getting suckered into taking shortcuts. As it turns out, all the old adages about success and hard work are true.

19. The Secret Structure Of Great Talks , by Nancy Duarte

The ability to move others through motivational speech is one of the greatest qualities of a true leader. Author and CEO Nancy Duarte gets it, and that’s why she developed this 18-minute talk to help aspiring leaders take their presentation skills to the next level.

Duarte dissects the speeches of Martin Luther King, Jr. and Steve Jobs to uncover the essential qualities of a great presentation. If leadership is your passion, be prepared to spend a lot of time talking in front of people.

20. How To Start A Movement , by Derek Sivers

Don’t let the name of this short TED Talk fool you – Derek Sivers isn’t calling for revolution or political anarchy. Using interesting footage, Sivers shows you how surprisingly easy it is to start a movement. As they say, it takes two to tango. That’s all that’s needed for leaders to inspire a movement.

21. Got A Meeting? Take A Walk , by Nilofer Merchant

“Sitting has become the smoking of our generation.” – Nilofer Merchant

In her TED Talk, business innovator Nilofer Merchant offers a simple message about the importance of maintaining a healthy lifestyle . Leaders spend a lot of time in meetings. Merchant suggests you turn your next one-on-one meeting into a “walking meeting.” Not only do you hit two birds with one stone – by meeting and elevating your heart rate – the simple act of walking allows your ideas to flow much better than they otherwise would sitting in a cramped office.

22. The Leaders Who Ruined Africa, And The Generation Who Can Fix It , Fred Swaniker

Africa has struggled to live up to its development goals, and its leaders are to blame, says TED Fellow and founder of the African Leadership Network Fred Swaniker.

Having lived throughout Africa, Swaniker highlights the vital role true leaders play in building a society, and what can happen in their absence. Swaniker’s description of the next great African leaders is anybody who wants to make a difference in their society, especially where strong institutions are lacking.

23. The Happy Secret To Better Work , by Shawn Achor

It’s generally assumed we have to work to be happy, but what if we have it backwards? That’s the argument psychologist and CEO Shawn Achor makes in this 2012 talk. Achor says we need to be happy independently of work , and only then will we be able to increase productivity and success in the workplace.

Searching for happiness in the workplace can be a deep rabbit hole that often leads to less happiness overall. This is an important message for leaders, who seek to inspire other people in their line of work. It just so happens that developing happiness outside the 9-5 hours is the most important for our health and success.

24. How to Fix a Broken School? Lead Fearlessly, Love Hard , by Linda Cliatt-Wayman

You don’t have to be a teacher to appreciate Linda Cliatt-Wayman’s inspirational talk about her time as principal at a failing school in Philadelphia. It didn’t take long for her to realize that leadership was more than just “laying down the law.” We won’t spoil it for you, but let’s just say she managed to turn around her struggling school. There were 3 key principles that helped her get there.

25. Trial, Error and the God Complex , by Tim Harford

If the title of Tim Harford’s TED Talk doesn’t pique your interest, nothing will. Harford, an economics writer who studies complex systems, talks about the importance of trial and error in achieving success. Except he doesn’t just “talk” about it, but presents the findings of his studies on complex systems.

As the title suggests, Harford’s talk centres on the concept of a God complex – refusing to admit the possibility of being wrong regardless of the complexity of the situation – and the importance of trial and error in achieving better results.  Go down the list, virtually every successful business leader used trial and error to perfect their craft.

26. The Surprising Habits Of Original Thinkers , by Adam Grant

“The greatest originals are the ones who fail the most, because they’re the ones who try the most.” – Adam Grant

Suffice it to say, all aspiring leaders want to be recognized for their creativity and originality. While creativity often lies within, psychologist Adam Grant studies the lives of “originals” – thinkers whose ideas transform the world. Over the course of 15 minutes, Grant explains the unexpected habits of original thinkers, and their fearlessness in the face of failure.

Fear of failure is one of the biggest inhibitors to success in all of life’s endeavors. While never easy, leaders must learn to overcome that fear. Studying the habits of original thinkers will teach aspiring leaders they “need a lot of bad ideas in order to get a few good ones.”

27. Your Body Language Shapes Who You Are , by Amy Cuddy

Four years and more than 38 million views later, Amy Cuddy’s powerful TED Talk has resonated with many aspiring leaders. As a social psychologist, Cuddy explains how “power posing” – showcasing a posture of confidence even when you don’t feel confident – can affect your brain chemistry and move you to positive action.

While some of the findings presented in the study are controversial among social scientists, Cuddy’s talk is a great reminder of the importance of projecting confidence in every situation . Whether that holds up to tests of academic rigor are less important.

28. How to Get Your Ideas To Spread , by Seth Godin

If you think the answer to Seth Godin’s talk is “social media,” try again. This TED Talk took place back in 2007, a few years before social media became as ubiquitous as it is today. As a leader, getting your ideas to spread requires more than just a Twitter handle. Godin, himself an author and marketing guru, explains the importance of standing out, and why even the craziest ideas can become the most successful ones.

29. Secrets Of Success In 8 Words, 3 Minutes , by Richard St. John

Analyst and bestselling author, Richard St. John, managed to condense 7 years of interviews into an unforgettable 3-minute presentation about what it takes to be truly successful. Believe us, nobody is as cognizant of your time as St. John. This 3-minute talk is normally presented as a 2-hour presentation to high school students.

30. Why We Do What We Do , by Tony Robbins

No list of inspiring TED Talks is complete without Tony Robbins, the globally renowned life success coach who has spent decades helping people achieve their dreams. Robbins shattered many preconceived notions about his work a mere 36 seconds into his presentation.

“I’m not here to motivate you, you don’t need that, obviously. Often that’s what people think I do, and it’s the furthest thing from it. What happens, though, is people say to me, ‘I don’t need any motivation.’ But that’s not what I do. I’m the ‘why’ guy. I want to know why you do what you do.”

He then goes into detail explaining the “invisible forces” that make us do the things we do. He also high-fives Al Gore in the front row. With more than 18 million views, Robbins’ TED appearance is one of the most popular.

There you have it. More than 8 hours of pure leadership inspiration to help turn you into the type of leader others admire, respect and want to follow.

>>To discover more invaluable leadership lessons from some of the most successful and inspirational leaders and leadership experts, become a Leader’s Edge monthly member to receive practical tools on how to be a leader, run a business and live a successful, fulfilling life! Hurry, join now to take advantage of our 14-day FREE trial !

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Leadership PowerPoint Templates (Best Leadership Styles and Models for PPT Presentations)

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In this blog post, we are going to share with you some of the best leadership PowerPoint templates . From here, you can find and download some of the professional leadership styles and models PPT template designs based on your requirements.

What is Leadership?

Leadership can be described as organizing a group of people and motivating them to achieve one or more goals. Leaders must have empathy, communication skills, honesty, integrity, and charisma. Leadership begins with great communication skills. Leaders strive to create an open environment in which every person has a voice as well as an opportunity to grow politically, professionally, and personally.

Characteristics of Leadership

A good leader inspires his followers through effective communication that emphasizes trust, competence, integrity, commitment, and caring about people’s concerns. A willingness to learn from others is important because it enhances one’s ability to communicate effectively; it also improves one’s credibility. Leaders must have the ability to multi-task, emotional strength and stability, flexible work ethic, persistence, and dedication. They must be able to resolve conflicts at all levels of an organization and between parties. Moreover, effective leaders are trustworthy with a strong sense of justice because they want what is best for everyone – not just themselves or their professional interests.

Who Are Good Leaders?

Leadership requires commitment, involvement in team activities, and results in the successful adoption of a vision that is aligned with organizational goals. Leaders must ensure that their teams (employees) understand their roles as well as the tasks ahead of them in achieving the same goal. In effecting change and innovation within organizations, there must be complete support from all hierarchies. Changing a culture is a team effort, and leaders must be open to ideas that will get the job done.

Leadership is not for everyone. Leaders must also have foresight; he knows where his organization needs to go from point A to point B and beyond. He envisions change scenarios not only in terms of the present but also the future: what will happen if the plan fails? how do we handle this? how do I prevent this from happening again?

Qualities of a Good Leader

• Leaders must be prepared for all team members to have different skill sets. The leader must also balance between giving credit where it is due and maintaining the integrity of the group. Sometimes, a leader’s job can be challenging because people are selfish in nature and leaders must make them feel like they are being heard while still getting everybody on board with the plan.
• The most effective leaders are those who best serve the interest of all parties involved: team members, managers, staff and management, even if it means giving up some personal goals or objectives for the greater good of the organization. The bottom line of effective leaders is really about selfless service rather than selfish gain.
• Leaders must learn to adapt or change in order to deal with different circumstances in respect of communication, analyzing data, decision making, and planning/organizing resources. They should also ensure that they create and maintain an effective team that has a good sense of direction, the urgency to get the job done or simply a shared vision.
• Leaders must be in the forefront of every battle and provide solutions to problems or challenges his team faces; this way, he inspires confidence not only amongst his team but also throughout the organization. After all, a confident leader is one who has complete trust with a strong sense of justice for everyone – not just himself or else.
• The most effective leaders are those who have a true passion for their profession. They really care about their people first before caring about numbers or other metrics that would improve an organization’s standing within its industry, amongst its peers, and even among other businesses in general.

Types of Leadership Styles

There are different types of leadership styles:

Task-orientated:  Task-orientated leaders focus on productivity within the immediate group(s) or organization with little concern for the overall health of the organization. These styles reflect an individual’s behavior in specific situations and environments while in a leadership role.

Laissez-faire style:  Laissez-faire style reflects a leader who is more concerned about their personal agenda where they tend to give orders without any sense of urgency or demands for accountability from subordinates.

Transformational leadership:  Transformational leaders inspire commitment through verbal persuasion rather than aggressive actions because they can identify with members of their team.

Other Important Leadership Styles & Models:

• Transactional Leadership
• Servant Leadership
• Democratic Leadership
• Autocratic Leadership
• Bureaucratic Leadership
• Charismatic Leadership
• Cross-cultural Leadership
• Coaching Leadership
• Affiliative Leadership
• Strategic Leadership
• Situational Leadership

Best Leadership PowerPoint Templates from the SlideSalad Marketplace

Leadership cannot be modeled in isolation. Observing how leaders react to various challenges will help you understand the leadership style. Leaders must motivate their team members so that everyone is on the same page and is ready to work hard together as a unit. So, we are introducing some of the best leadership styles and models PowerPoint templates you can use for your business, companies, or education purposes. All our premium templates got many attractive features such as:

• Fully editable slides
• Professional slide backgrounds and image placeholders
• Unlimited theme colors
• Completely customizable vector icons
• Two screen resolutions: 4:3 and 16:9
• Lifetime support
• Lifetime updates

1. Lewin’s Leadership Styles Frameworks PowerPoint Template – Leadership PPT Template

This is one of the best leadership PowerPoint templates that explain the theory of Kurt Lewin. He defines that, the perfect management style is always dependent on the situation at hand as well as the manager’s personality. There are three kinds of leadership styles that can be used in different situations. These are Autocratic, Democratic and Laissez-faire leadership styles.

An autocratic leader is someone who generally makes it clear to all employees that they are there for work results rather than personal relationships. When issues arise, they tend to have the final say in making decisions. This type of leadership style is something that relies heavily on the trust of the employee.

Democratic leaders, on the other hand, prefer to have a level of consultation with all employees before making decisions instead of handling things alone. Individual opinions are highly valued as well as participation from all members. Group processes are encouraged within this leadership style, which relies heavily on an inclusive relationship amongst team members rather than an exclusive one based solely on personal loyalty to the boss.

Laissez-faire leaders tend to give their employees a lot of freedom and autonomy that they are expected to use in getting their jobs done. They are also known as “hands-off” leaders who are there merely for guidance and direction but not necessarily involve themselves in the day-to-day operations. Under this type of leadership style, subordinates make all decisions that may lead to failure without consulting them first.

2. Transformational and Transactional Leadership PowerPoint Template – Top Selling Premium Leadership Practices PowerPoint Template

Leadership has always been an important part of business development. This top premium PPT template for leadership contains two types of leadership styles:

• Transformational Leadership Style: Transformational leadership focuses on inspirational influence beyond current productivity levels, while transactional leadership focuses on effective management of subordinates, which in effect results in higher productivity (Bass & Avolio, 1994).
• Transactional Leadership Style: The transactional Leadership style presents a much more effective way of leading and can be implemented in almost any type of business. The concept behind this style is to make minimal demands on workers while giving them as many rewards as possible. Transactional leaders recognize that the needs, wants, and desires of the employees have changed drastically throughout the years due to advances in technology and social structure.

3. Three levels of leadership Model PowerPoint Template – Stunning Leadership PPT Themes for Leaders

James Scouller is the founder of this model, which he has been developing since 1994. In his research, he discovered a pattern that most if not all leaders have, and that is how they interact with people that are important to them in their life. He saw leaders often leading in these three very distinctive ways: public leadership, private leadership, and a personal leadership style which includes interaction with family and friends. These different styles of leading can be obvious when one observes the leader’s behavior. Some of the features of this premium three levels of leadership model PPT template includes:

• Fully customizable slides
• 4:3 and 16:9 screen ratios
• Unlimited color themes
• Colorful infographics
• Thousands of vector icons
• Premium graphics and objects
• Free lifetime updates
• Free lifetime support

4. John Maxwell 5 levels of leadership PowerPoint Template – Minimalist Leadership Styles PPT Templates

In this comprehensive leadership styles PowerPoint template, we are checking the 5 levels of leadership presented by John C. Maxwell. John C. Maxwell’s 5 levels of leadership is an interesting way to look at information about leadership and knowing your place in the team.

• Position – defines our role in an organization, relationships, functions available to us at work, and achievements. It is the place in which we hold an office or a title; it defines what we do and does not have authority over.
• Permission – defines the amount of freedom we allow ourselves within an organization, how comfortable we feel taking risks; it also defines the choices available and those which could be considered for the future.
• Potential – defines our ability to grow beyond our current position through skill development, taking on new challenges, and seeking out different experiences; Potential is what we believe we can become with proper motivation and effort.
• Production – defines what we produce from within ourselves as leaders; It is the amount of work or wealth that comes from an individual or organization over time. If somebody doesn’t produce anything, he/she isn’t considered a good leader; there are no more excuses about your inheritance or family name! As business owners, you need to get production from yourself and/or others around you.
• Position of influence – defines the size an individual has in relation to others; it is the amount of people we impact either positively or negatively; it also includes leadership positions which can be expressed through a large group. It is important for individuals to seek effective ways of influencing those around them for the betterment of all parties concerned.

5. Seven Transformations of Leadership PowerPoint Template – Clean Leadership Management PowerPoint Templates

This beautiful PowerPoint template is presenting the research of Seven Transformation of Leadership. Seven Transformations of Leadership is a leadership theory presented by David Rooke and William R. Torbert. It says there are seven types and styles of “action logic” that leaders develop and master as they progress. This logic determines how leaders assess their surroundings and their reactions when they are being put in challenging situations. One can understand the concept of the leadership theory by understanding “action logic”. Action logic is a specific way in which people think and act. It is used to assess one’s surroundings and create an effective strategy for action. These action logics styles are:

• The Opportunist
• The Diplomat
• The Achiever
• The Individualist
• The Strategist
• The Alchemist

6. Situational Leadership Model PowerPoint Template Diagrams – Professional Leadership Training PPT Templates

The Situational Leadership Model was developed in 1969 by Ken Blanchard and Paul Hersey. This model was the result of years of research on what makes a good leader. The primary goal was to create a way that would help leaders and managers get the very best out of their employees regardless of who they are or what they do for a living. There are four leadership styles presented in this professional PowerPoint presentation template:

• S1: Directing
• S2: Coaching
• S3: Supporting
• S4: Delegating

Once you are done editing the template, upload it to Google Drive or OnDrive to access it on any device. If you are interested, you can check some of our Premium Google Slides and Premium Keynote Templates.

7. Leadership Success Profile PowerPoint Template Diagrams – Elegant Leadership Themes for Microsoft PowerPoint

This cool PPT template designs are showcasing the standards of the leadership success profile. According to Maxwell (1990), there are four levels of leadership, the highest being level IV, which is “Proactive”. Level III is “Reactive,” and level II is “Coordinator,” while level 0 is the lowest and most common type of leadership.

Key Knowledge:  A leader must have followers, as well as an understanding of the group or organization they are leading. A leader must have communication, project management training, and the development of others.

Key Experience:  Key experience is the second most crucial component of leadership, a leader must have role models from which he can learn; this includes teachers and coaches.

Leadership Competencies:  Knowledge and experience are the two most crucial components when it comes to leadership; however, competency is what sets excellent leaders apart from their peers. Some of these include change management, conflict resolution, strategic thinking, and effective decision-making.

Leadership Personal Attributes: A leader should have the ability to focus, has discipline and can perform well under pressure, as well as many other qualities that make a good leader great.

Personal Leadership Style:  A leader must be able to understand the strengths as well as weaknesses of themselves in order to better lead their organization or group.

You can also check some of the fully animated PowerPoint templates listed in the SlideSalad marketplace.

8. Fiedler’s Contingency Model PowerPoint Template – Creative Leadership Discussions PPT Templates

If you are looking for some of the best leadership models PowerPoint templates, then get these amazing PPT templates for illustrating Fiedler’s Contingency Model. Fiedler’s contingency model of leadership is a significant management theory that addresses the nature and impact of situational variables on leaders and leadership. Leadership behavior and effectiveness are dependent upon the leader’s ability to recognize the context in which they operate, analyze what may require change, and make appropriate decisions. The contingency model describes three key situational factors which can influence leadership efficacy: task structure, relationship systems, and leader-member relationships . Instead of downloading some free leadership PowerPoint templates, get this fully editable PPT template that is packed with professional infographics, vector icons, unlimited color schemes, two display ratios; 4:3 and 16:8, and more.

9. Blake-Mouton Managerial Grid Model PowerPoint Template – Business Leadership PowerPoint Templates for Download

Blake and Mouton developed a quadrant-based approach to leadership known as the managerial grid model. The model attempts to quantify leadership styles, with the type of leader fitting into one of four distinct categories based on their focus on people versus production. The grid has two axes, measuring:

• Concern for people – What kind of support are you offering your team members?
• Concern for production – How much attention do you put on making sure the task is completed?

The two axes cross each other so that they can be graphed as a grid with four quadrants. This fully customizable PowerPoint template covered the Blake-Mouton Managerial Grid Model is a professional way for easy presentation.

10. Likert’s Leadership Styles Model PowerPoint Template – Recommended Leadership Templates for PowerPoint Presentations

Likert Management System is a style of leadership in which the manager (Leader) attempts to develop an attitude or behavior pattern in Employees. Leaders try to improve the productivity and quality of work through such measures as improved motivation, communication, interaction, influence, decision-making process, goal setting, and control process with the help of Employees.

The Four Management Systems of Likert are:

• Autocratic (Authoritarian or Directive Style) Management System
• Democratic (Participative or Consultative Style) Management System
• Laissez-faire (Permissive or Neutral Style) Management System
• Authoritative (Friendly or Assertive Style) Management System

11. Leadership Style Matrix PowerPoint Template – Multipurpose Corporate Leadership Training PPT Template

Buy this fantastic PPT template created for explaining the Leadership Style Matrix. The Leadership Style Matrix was developed by Eric Flamholtz and Yvonne Randle and published in their book “Growing Pains” in 2007. The Leadership Style Matrix is divided into four quadrants and two-axis X and Y. The X-axis measures the task, and Y-axis measures employee capabilities. It offers a useful strategy for dealing with conflicts between style and capability. The matrix comprises four quadrants, which not only offer insight into an individual’s style but also helps to develop workgroups by creating synergies within each team. This model highlights a specific style for each team member, and it defines the working relationships that will help a leader to manage his or her individual workgroup successfully. The matrix also explains how different styles can be used to create high-performance teams by leveraging employee capabilities effectively. Each quadrant of the matrix has its own characteristics and is tied to a specific leadership style. The interactions between these styles, i.e., within a single team, defines how the leader should manage their staff members to achieve the best results for a project or venture.

12. Path-Goal Leadership Theory PowerPoint Template – Leadership Management PPT Template

The Path-Goal Theory of Leadership was developed by Martin Evans and Robert House in 1971. The theory is based on the expectancy theory of motivation, a proposition that people are motivated to behave in ways that will lead them to achieve certain outcomes (rewards). The key assumptions of this research center around the idea that employees have a clear understanding of expectations and goals. The theory assumes leaders are able to influence and control the motivation of subordinates in order for them to achieve desired goals. Leaders must show competence for employees to follow them willingly. Successful leadership is when subordinates are able to mold their own goals and objectives through the leader’s guidance. Thus, the path-goal theory incorporates a form of leadership similar to what managers do in everyday life. Purchase this Path-Goal Leadership Theory PowerPoint Template for your presentation!

13. Theory X and Theory Y and Theory Z PowerPoint Template – Professional Leadership Training PowerPoint Template

This simple and minimalist PowerPoint theme is excellent support for presenting Theory X and Theory Y, and Theory Z. Theory Y and Theory X are terms first used by the 20th-century psychologist Douglas McGregor. According to McGregor, “theory Y” describes an individual’s belief that their goals can be best achieved through cooperation rather than competition. The opposite of this is “theory X,” which focuses on the idea that competition and self-interest are necessary for success.

Theory Z was developed by Dr. William Ouchi while he was a professor at UCLA’s School of Management in the 1980s. Theory Z is based on the idea that Americans can improve their management style by not copying the Japanese style but by identifying what American managers do and what makes them effective and adding some innovative features.

14. ABCD Trust Model PowerPoint Template – Leadership Development PPT Themes and Designs

ABCD Trust Model was proposed by The One Minute Manager Ken Blanchard in 2013. In his book, he talks about the ABCD Trust Model. These four attributes are the basis of trust. The four constituents of this acronym stand for:

A – Able – you have to be able to do your job.

B – Believable – your inner convictions or beliefs must be acceptable.

C – Connected – with the organization and its people.

D – Dependable – you have to be reliable.

Applying the ABCD Trust Model in practical terms means that leaders, managers, and associates must be accountable in delivering on promises they make to one another; others, in turn, must treat each other fairly in performing roles and responsibilities. You can present this model in even webinars. Also, have a look at some of the best webinar PowerPoint templates selling on the SlideSalad marketplace.

15. Tannenbaum-Schmidt Leadership Continuum Model PowerPoint Template – Best Leadership Models PowerPoint Template

The Tannenbaum-Schmidt Leadership Continuum model is a simple leadership theory model. It was developed by Robert Tannenbaum and Warren H. Schmidt in 1958 and titled ‘How to Choose a Leadership Pattern. The leadership pattern model is based on the idea that a leader will grow and develop in terms of their leadership skills and abilities. This means that a level one leader cannot be expected to do everything at once if they are placed in a position that requires them to complete many complex tasks as well as maintain morale amongst co-workers and subordinates. Tannenbaum and Schmidt outlined seven points on the continuum to make it easy to understand how different leaders behave at various points on the continuum. To be considered a good leader, a person must be able to master the behaviors on both ends of the continuum.

There are a few things to consider before moving someone along the continuum. The most important of these prerequisites is that their values match those required by the position. Get this premium leadership PPT template rather than downloading free PowerPoint templates.

16. Goleman Six Leadership Styles PowerPoint Template – Leadership Styles PowerPoint Designs for Presentations

Daniel Goleman identified six different leadership styles in his book Primal Leadership, each with different emotional effects. The six styles are displayed as a continuum, with each style building on the success of the previous style while not being dependent on it. Start at the top of the continuum and work your way down to develop an understanding of them all. These are the following:

• Commanding leadership style
• Visionary leadership style
• Democratic leadership style
• Coaching leadership style
• Affiliative leadership style
• Pacesetting leadership style

If you are interested, you can explore some of the most popular templates collections about the best team management, development frameworks PowerPoint templates . Most of the premium templates are completely customizable and have many features that fully animated slides, slide transitions, image placeholders, slide backgrounds, premium graphics, brand colors, infographics, and more.

17. The Emotional Competence Framework PowerPoint Template – Leadership Standards PowerPoint Templates and Themes

Daniel Goleman’s book “Working with Emotional Intelligence”, emotional competence affects the performance of employees in the workplace, which is a learned ability that is based on emotional intelligence.” The main focus of emotional competence is the cognitive aspect. Cognitive development, social skills, and personality development from childhood to adulthood. In adulthood, an individual’s behaviors, values & attitudes are observed through their actions which can lead to benefits or problems within the work environment. Emotional competence is divided into two categories:

• Personal Competence (Self-Awareness, Self-Regulation, and Self-Motivation)
• Social Competence (Empathy and Social Skills)

18. Belbin’s Team Roles Model PowerPoint Template Diagrams – Best Leadership Frameworks PPT Themes and Designs

Belbin Team Roles is a model that identifies nine different specific roles of team members in successful teams. According to Dr. Belbin, every successful team contains all nine roles, and the team’s full potential is realized only when it has all nine. These roles range from leaders and idea people to harmonizers who bring harmony among members. Belbin’s Team Roles mentioned in this creative PowerPoint template includes:

• The Monitor-Evaluator
• The Coordinator
• The Implementer
• The Completer-Finisher
• The Specialist
• The Resource Investigator
• The Team Worker

Each role has a different function within the team which leads to strengths and weaknesses in each individual. Every role is unique as all individuals are different individuals; however, every person does fall into one of these roles.

19. Leadership Process Model PowerPoint Template – Top Leadership Transformation PowerPoint Template

Dunham and Pierce (1989) define leadership as an interactive process of influence through which a leader can assist followers in attaining their higher-order needs. The learning involved in this process considers situational factors and individual differences among followers. The four factors of the Dunham and Pierce Leadership Process Model PPT template are:

• The Context

The leader uses his or her knowledge and skill to influence the followers in their environment in such a way that they are more successful than before. This can be accomplished by: leading people toward goals, providing direction, communicating information, or helping followers make decisions. Whatever the method, leaders must create a vision for an organization and provide feedback on progress towards achieving the vision.

20. Skill Will Matrix PowerPoint Template Slides – Unique Leadership Strategies PowerPoint Designs

The skill will matrix is a simple framework used to assess and determine an individual’s (team member) skill level and willingness to perform a specific task or role. The Skill-Will Matrix has four quadrants: Differently skilled people with different levels of motivation can be grouped into four categories.

• The upper-left quadrant of the skill will matrix is for “highly skilled and highly motivated” people who are a manager’s dream team members. They are self-directed, disciplined, and ready to work hard to achieve the goals they set themselves.
• The upper-right quadrant is for “highly skilled but low motivation” people. They can be difficult to manage because they are not motivated to work hard without the proper incentive or reward. They are motivated when they feel that their opinions are valued and solicited by management and team members.
• The lower-right quadrant is for “low skilled but high motivation” people who make excellent candidates for a team leader position since they will work hard to motivate others, although they lack the qualification required for actual leadership roles.
• The lower-left quadrant is for “high skilled and low motivation” people who will only accept management positions if they can excel at it; otherwise, they become a drain on the company because their sense of duty and dedication is not enough to motivate them to work hard or improve themselves. They have no incentive to lead any team, even though they have great potential for leadership roles.

Because of this high potential, all managers should be attentive to these individuals, giving them the opportunity to prove their leadership skills by finding other ways to contribute to the company’s success without leading a group. This best clean and minimalist leadership PowerPoint is a great choice for pitch deck presentations , project management presentations, and more.

Conclusion:

Leadership is about putting your own personal agenda aside and focusing on improving the overall health of your organization as well as the welfare of your subordinates. The greatest leaders are those who truly care for their people during tough times by remaining calm, cool, and collected so that they can be open to new ideas, better ways, or alternative perspectives. These best leadership PowerPoint templates are one of the top professional leadership styles and models PPT themes you can download without thinking. Purchase the needed templates from the SlideSalad marketplace and start your presentation today!

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[Updated 2023] The 5 Leadership Styles Along (With PPT Templates Included)

Lakshya Khurana

Leaders make an organization, whether a company, a school, or a government organization. The main goal of a leader is to establish an environment conducive to success, with unrelenting focus on encouraging communication and teamwork among people they lead. 

Leaders also provide direction, vision and inspire and motivate people to achieve organizational goals. Competent management and effective leadership are necessary for businesses to meet their goals.

How you manage your team depends on your personality and how you interact with others, regardless of the size of your team (it may be 10 or 10,000). Knowing your preferred style of leadership is the first step to enhancing it. 

In this blog, we'll discuss the most-renowned five prevailing leadership styles with readymade PowerPoint Templates.  and then go into how to identify and cultivate your own style. 

If you want to improve your leadership skills , read our full blog here .

Coming back to leadership styles, the five most common leadership styles are autocratic, participative, delegative, transactional, and transformational. Each style has its advantages and disadvantages when it comes to leading people.

The leader takes complete control over all decisions, usually excluding staff from the process and dictates procedures and goals.

• Participative

Leaders are open to employee feedback, value their teams' opinions, and involve them in decision-making. Participative leaders pay close attention to the individuals they lead.

Autonomy and adaptability are values that such leaders support. The freedom this leadership style delegates can be advantageous when the people being managed are highly trained, educated about their occupations, and capable of working efficiently with minimum monitoring.

• Transactional

The transactional leadership style adheres to traditional managers' stereotypes, emphasizing organization, monitoring, performance, compliance, and goal-setting while motivating employees through incentives and penalties.

• Transformational

Vision is everything, as these managers encourage their staff members and use empowerment, empathy, and recognition to energize their groups, assist them in achieving their objectives, and inspire them to go above and beyond to realize a common purpose.

This primer done, we now dig deep into top 15 PPT Templates that SlideTeam has curated to help you identify and build leadership styles of your own. 

As always, each of leadership ppt templates are 100% editable and customizable. The content-ready nature means you get a starting point for your presentations and a much-coveted structure. The editability feature means you can tailor the presentation to your audience requirements.  

Let’s take a tour now!

Template 1: Leadership Styles Quadrant Matrix for Motivation Enhancement

Positive thinking and a clear vision create motivational leadership. Motivational leaders are action-oriented, establish clear objectives, and give their people the resources and tools needed to succeed. They bring out the best in their team members and encourage them to work together toward a common objective. The quadrant template offered here evaluates where you stand on the opposing forces of direction versus supporting behaviors. This is a clear visual indication of your leadership style and helps you decide what to do to improve. Get this template now, and start work on your leadership skills with immediate effect. 

Template 2: Leadership and Board Leadership Styles Best PPT PowerPoint Presentation Gallery Deck

Increase focus on issues affecting individuals with our predesigned leadership and board leadership PPT Template. Use the presentation template to discuss leadership styles like commanding, visionary, affiliative, democratic, pacesetting, or coaching. It will help you to improve your leadership and provide good governance for your organization. Download now and deliver your ideas. The tabular format mapping each leadership style to a leader’s mannerisms makes it clear to distinguish between the types.  

Template 3: Six Leadership Styles for Every Business

The six leadership styles that US author and world-renowned authority on emotional intelligence Daniel Goleman developed are illustrated in this PPT Template. For project managers and business owners, the idea has enormous advantages. It aids in creating a brief evaluation and a clear connection of the effects of leadership on people and their surroundings. Most often, leaders must be able to change their leadership styles as the situation demands. Download now to study the six styles that range from visionary to autocratic.

Template 4: Leadership Styles Economy Study Considering Business Level Strategies

Strategy formulation is an essential process in business. Talk in-depth about leadership considering business-level strategies and their significance. Use this PPT Template to research theories and inform your audience about diverse leadership styles and economic studies. This PPT template is a handy tool for providing direction for your actions.

Template 5: Leadership and Broad Leadership Styles Talk PPT Presentation Portfolio Styles

Use this fantastic PPT Template, designed to describe broad leadership styles. This slide presents a leadership style based on the relationship and tasks. It also explains how leadership styles can use employee capabilities to establish high-performing teams. Download now and demonstrate how a leader should manage their team to complete a project or business venture.

Template 6: Customer Management Systems Leadership Styles Concentric Marketing Commerce Strategies

The customer service industry has to use leadership strategies pretty frequently. Analyzing each one and finding the best for your business is key for business success. Use our readymade PPT Templates to compare and contrast leadership styles and create concentric marketing commerce strategies. Download and obtain the information.

Template 7: Four Leadership Styles Hersey and Blanchard Corporate Leadership

According to the Hersey-Blanchard Model, no leadership style is superior. The approach advises that leaders should adapt their techniques to those they lead and their strengths rather than concentrating on workplace conditions. Our predesigned PPT template on four leadership styles helps discuss the task and relationship-relevant leadership styles. Download now and see leadership as a fluid dynamic than mere fixed personality traits. 

Template 8: Leadership Styles Based on Authority Democratic Corporate Leadership

Leaders must showcase specific emotional intelligence skills like self-confidence to have their way. They must create a vision and motivate others to follow it. Use our predesigned PPT template to discuss leader’s action plans according to their leadership style. It will help them to decide what should be done and how to do it. The ultimate aim is to achieve strategic business goals. Get this template now!

Template 9: Four Effective Change Leadership Styles for Managers

Influential leaders adapt their behavior or approach to leadership in response to conditions. This PPT Template presents data on leadership styles. You can discuss authoritative, rational, positive influence, and supportive leadership styles in detail and choose what fits best for effective business results. This PPT offers an excellent foundation for defining the extent of change and determining how to support the workforce during the transition. Get this presentation template now!

Template 10: Situational Leadership Style Matrix with Followers Readiness

Leaders must modify strategies to suit conditions. Leaders deal with levels of follower-readiness by altering their relative emphasis on work and relationship behaviors. Use our PPT template matrix to showcase leadership style behavior according to tasks. Use this template to also discuss development levels of followers and build strategies. Get this template now!

Template 11: Leadership Styles Based on Authority Consultative PPT PowerPoint File Shapes

Recognizing your leadership style lets you give staff members the right direction and feedback. Disperse knowledge on authority-based leadership styles such as autocratic, democratic, free-rein, and persuasive using our PPT Template. Download this presentation template now!

Template 12: Key Behaviours of Four DISC Leadership Styles

Introducing the DISC model PPT Template to discuss the critical behavior of leaders to understand themselves. The DISC model analyses four personality factors to determine a person's overall behavioral style and preferences, i.e., Dominance(D), Influence(I), Steadiness(S), and Consciousness(C). Using this PPT template, you can discuss behavior and its impact on the organization. Download and share your ideas with your team to create the maximum impact with minimum fuss. 

Template 13: Organizational Multiple Leadership Styles Matrix

Leadership styles and techniques can differ depending on how complicated an organization’s structure is. Highlight organizational multiple leadership styles with this matrix chart PPT Template. Business leaders can use this presentation template to discuss leader details, goal alignment, unstructured issues, acceptance, fairness, disagreement, and common acceptance. Download now!

Template 14: Addressing Strategic Leadership Styles Strategic Planning Guide for Managers

This PPT Template allows you to display details about leadership, mostly on innovative, directive, and collaborative styles. You can discuss the qualities of each leadership style and advantages and disadvantages. Compare and contrast and make decisions. The slideshow is helpful for strategic planning managers and entrepreneurs. Get it now!

Template 15: Leadership Styles Integrated Model for Employee Management

This predesigned PPT Template works as a guide to improve the performance of others. You can use this integrated model to discus motivation, recognition, delegation, flexibility, structure, and global focus. It will be helpful to modify your leadership style according to the situation. Download now and start on the path to build a strong leadership style.

LEADERSHIP IS A MUST!

Leadership is both pleasing and challenging. The opportunities for rewards are numerous, but so are the obligations. Everyone has what it takes to be a leader in their field. Here is the road map to becoming a good and effective leader. Use these templates to make the necessary modifications and establish excellent leadership in your organization.

FAQs on Leadership Styles

What are the four main leadership styles.

No company can run effectively without leadership. Your leadership style determines how you influence those around you and how your actions affect the success of your business or division. The four main leadership styles are:

In autocratic leadership, a single person controls the organization or team. An autocratic boss dictates everything to subordinates. 

The democratic leadership method entails soliciting feedback and subordinates; the idea is that everyone can participate in decision-making.

• Laissez-faire

It entails empowering your staff, remaining detached, and trusting them to complete the task without continual supervision or questioning.

Transformational leadership involves establishing an ambitious goal and organizing your team around it.

What are the seven leadership styles in management?

Business leaders can adapt and lead effectively in any situation by being aware of the traits of below seven different leadership styles:

• Autocratic or Authoritative Leadership
• Democratic or Participative Leadership
• Coaching Leadership
• Strategic Leadership
• Transformational Leadership
• Laissez- Faire Leadership
• Charismatic Leadership

Each of these styles has both pros and cons attaches to it. The best course of action for a leader is, of course, to see which style fits which situation. This is very hard to do in practice, but good leaders do give it their best shot. 

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Leadership is essential for any company to succeed, as leaders are responsible for directing and motivating their teams to achieve their goals. Leaders must be able to effectively communicate their vision and strategies to get the best out of their employees. As you can imagine, this is the central theme of this creative template. With eye-catching blue backgrounds and designs that simulate computer windows, you will be able to make a complete presentation on this topic and even propose some practical activities at the end of the presentation. Don't wait any longer and download it to discover all the resources included.

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5 Principles of Purposeful Leadership

by Hubert Joly

Summary .   

The traditional model of the leader-hero who saves the day, knows it all, is the smartest person in the room, and is too often driven by power, fame, glory, or money is not appropriate in today’s environment. People today expect a different kind of leader. While each company needs to define its own leadership point of view, the author presents five attributes that characterizes leaders who are able to unleash the kind of human magic you see at work at some of the most high-performing companies. First, be clear about your purpose. Second, be clear about your role. Third, be clear about whom you serve. Fourth, be driven by values. Finally, be authentic.

Growing up, I thought successful leaders were supposed to figure out all the answers on their own. Being smart — and making sure everyone else knew it — seemed to be their most striking attribute. The best schools were supposed to lead to the best jobs, which produced the best leaders. Power, fame, glory, and money were the measure of professional success. Early in my career, prominent business leaders like GE’s Jack Welch were revered for their intellect, strategic sense, and hard-charging style. They were considered infallible geniuses, inspiring a quasi-cult following.

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Strategic Agility In Action: Leaders Empowered At Texem’s Transformative Liverpool Programme The recent TEXEM Strategic Agility and Inspiring Change programme, held from August 26th to 29th, 2024, was a remarkable gathering that left an indelible mark on all who attended. This executive development programme, which took place in the vibrant city of Liverpool, was not just a capacity development programme but an immersive experience that combined cutting-edge leadership insights with practical applications, all aimed at empowering leaders to navigate the complexities of today’s turbulent environment. Hosted at the prestigious Hilton Liverpool City Centre, the programme commenced with a warm welcome on Monday, August 26th. The morning session, led by the esteemed Prof. Rodria Laline, delved into the foundations of strategic agility, setting the stage for a week of deep learning and transformative discussions. Participants were introduced to the principles of strategic agility, exploring how these concepts provide a critical leadership edge in times of uncertainty—the afternoon continued with an exploration of effective leadership in change management, where executives learned best practices in implementing change—a crucial skill in maintaining organisational resilience. Tuesday, August 27th, was a day that blended rigorous academic inquiry with an unforgettable practical experience. Dr Alim Abubakre, Founder of TEXEM, UK, guided participants through a detailed analysis of strategic agility versus agile strategy, drawing on the resource-based view to provide a robust framework for leveraging organisational strengths to win. Specifically, the presentation on “Strategic Agility vs. Agile Strategy: Leveraging the Resource-Based View” provides leaders with a clear distinction between these two concepts, emphasising the importance of organisational flexibility and rapid adaptation in a dynamic business environment. By leveraging unique resources and capabilities, leaders can sustain competitive advantages and foster resilience against disruptions. The benefits include enhanced decision-making, faster response times, and the ability to capitalise on emerging opportunities, ultimately driving sustainable success in turbulent times. The evening offered a unique opportunity to visit Liverpool Football Club, where participants engaged in a working trip that transcended the usual confines of corporate capacity development programmes. Led by the legendary Ian Callaghan, who holds the record for the most appearances for Liverpool and was a key player in their FA Cup success and England’s World Cup-winning squad, this guided tour provided not just inspiration but a living example of dedication, teamwork, and strategic thinking. The third day, Wednesday, August 28th, facilitated by Ambassador Charles Crawford, brought forward big ideas on how to make meetings more effective—a critical component of strategic agility. Participants were then challenged to engage in practical speaking exercises, sharpening their communication skills, which are essential for motivating teams and driving change. The afternoon was dedicated to case studies highlighting diplomatic agility, providing real-world examples of how strategic thinking can be applied in high-stakes situations. The day concluded with discussions that distilled vital messages from the day’s activities, leaving participants with actionable insights to bring back to their organisations. The final day, Thursday, August 29th, under the guidance of Prof. Roger Delves, was a masterclass in emotional intelligence (EQ) and transformational leadership. Participants explored how strategic relational management fuels sustainable success, delving into authentic and purpose-driven leadership. This session culminated the week’s learning, bringing together the threads of strategic agility, change management, and leadership authenticity into a coherent approach to leading in uncertain times. Throughout the programme, participants were engaged in learning and networking during informal discussions over lunch and dinner, creating connections that are sure to last well beyond the programme. The farewell dinner on Thursday evening marked the conclusion of a week that was as much about building community as it was about gaining knowledge. The programme’s methodology encompasses group and individual impactful activities, peer-to-peer learning, games, observation practice, and self-reflection to make learning fun, engaging, and insightful. This approach not only made the sessions more enjoyable but also ensured that the insights were deeply ingrained, practical, and immediately applicable. Participants left with a sense of accomplishment, armed with actionable strategies to drive organisational success. The benefits of this methodology were manifold—enhanced retention of knowledge through active engagement, a supportive learning environment that fostered collaboration, the opportunity to immediately apply new skills in a safe setting, the development of critical thinking through interactive exercises, and the ability to reflect on personal leadership styles and their impact. Testimonials from the participantss underscored the programme’s success: “The programme is all about strategic agility, and we’re living in times of disruption. The programme has equipped me with some valuable skills in terms of emotional intelligence, in terms of transformational leadership, and these are quite important ingredients and tools for any organisation that wants to thrive and succeed.” Rabia Wanka, Head of Oil and Gas Transactions, NEXIM Bank. “A lot has been learned. And, specifically, I like the energy. Sincerely, I’ve had other international programmes, but this is with a difference, the faculties that were brought, the way the programme is structured, you know, around organisation and around self. It’s distinct, and I want to recommend it to leaders, to come to TEXEM.” John Tizhe, Executive Director, NPF Microfinance Bank. “Well, I was coming from an environment where agility is the language, it is not strange…to me, but this programme further exposed me more, like, a firsthand information, … with this insight I’ve gotten from here, it’s going to help me to move even more faster…” – Olusola Faleye, MD/CEO, Lagos Building Investment Company Plc (LBIC). For those who missed this programme, it is not an exaggeration to say that they missed a truly transformative experience. The insights gained were not just theoretical but practical, providing leaders with the tools they need to drive their organisations forward with confidence and agility. As we all know, the ability to adapt and lead in turbulent times is not just a luxury but a necessity for sustainable success. Those who were fortunate enough to attend now carry with them a strategic edge that will undoubtedly set them apart in their respective fields. Conclusively, in the words of Charles Crawford “There’s always a fascinating dynamic tension between Agility (quick thinking and quick movement NOW!) and Strategy (setting a long-term goal then methodically driving towards it without getting distracted). This course allowed its distinguished participants to think about this tension – and to learn specific skills for getting the balance right.”

The recent TEXEM Strategic Agility and Inspiring Change programme, held from August 26th to 29th, 2024, was a remarkable gathering that left an indelible mark on all who attended. This executive development programme, which took place in the vibrant city of Liverpool, was not just a capacity development programme but an immersive experience that combined cutting-edge leadership insights with practical applications, all aimed at empowering leaders to navigate the complexities of today’s turbulent environment.

Hosted at the prestigious Hilton Liverpool City Centre, the programme commenced with a warm welcome on Monday, August 26th. The morning session, led by the esteemed Prof. Rodria Laline, delved into the foundations of strategic agility, setting the stage for a week of deep learning and transformative discussions. Participants were introduced to the principles of strategic agility, exploring how these concepts provide a critical leadership edge in times of uncertainty—the afternoon continued with an exploration of effective leadership in change management, where executives learned best practices in implementing change—a crucial skill in maintaining organisational resilience.

Tuesday, August 27th, was a day that blended rigorous academic inquiry with an unforgettable practical experience. Dr Alim Abubakre, Founder of TEXEM, UK, guided participants through a detailed analysis of strategic agility versus agile strategy, drawing on the resource-based view to provide a robust framework for leveraging organisational strengths to win. Specifically, the presentation on “Strategic Agility vs. Agile Strategy: Leveraging the Resource-Based View” provides leaders with a clear distinction between these two concepts, emphasising the importance of organisational flexibility and rapid adaptation in a dynamic business environment. By leveraging unique resources and capabilities, leaders can sustain competitive advantages and foster resilience against disruptions. The benefits include enhanced decision-making, faster response times, and the ability to capitalise on emerging opportunities, ultimately driving sustainable success in turbulent times.

The evening offered a unique opportunity to visit Liverpool Football Club, where participants engaged in a working trip that transcended the usual confines of corporate capacity development programmes. Led by the legendary Ian Callaghan, who holds the record for the most appearances for Liverpool and was a key player in their FA Cup success and England’s World Cup-winning squad, this guided tour provided not just inspiration but a living example of dedication, teamwork, and strategic thinking.

The third day, Wednesday, August 28th, facilitated by Ambassador Charles Crawford, brought forward big ideas on how to make meetings more effective—a critical component of strategic agility. Participants were then challenged to engage in practical speaking exercises, sharpening their communication skills, which are essential for motivating teams and driving change. The afternoon was dedicated to case studies highlighting diplomatic agility, providing real-world examples of how strategic thinking can be applied in high-stakes situations. The day concluded with discussions that distilled vital messages from the day’s activities, leaving participants with actionable insights to bring back to their organisations.

The final day, Thursday, August 29th, under the guidance of Prof. Roger Delves, was a masterclass in emotional intelligence (EQ) and transformational leadership. Participants explored how strategic relational management fuels sustainable success, delving into authentic and purpose-driven leadership. This session culminated the week’s learning, bringing together the threads of strategic agility, change management, and leadership authenticity into a coherent approach to leading in uncertain times. Throughout the programme, participants were engaged in learning and networking during informal discussions over lunch and dinner, creating connections that are sure to last well beyond the programme. The farewell dinner on Thursday evening marked the conclusion of a week that was as much about building community as it was about gaining knowledge.

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The programme’s methodology encompasses group and individual impactful activities, peer-to-peer learning, games, observation practice, and self-reflection to make learning fun, engaging, and insightful. This approach not only made the sessions more enjoyable but also ensured that the insights were deeply ingrained, practical, and immediately applicable. Participants left with a sense of accomplishment, armed with actionable strategies to drive organisational success. The benefits of this methodology were manifold—enhanced retention of knowledge through active engagement, a supportive learning environment that fostered collaboration, the opportunity to immediately apply new skills in a safe setting, the development of critical thinking through interactive exercises, and the ability to reflect on personal leadership styles and their impact.

Testimonials from the participantss underscored the programme’s success: “The programme is all about strategic agility, and we’re living in times of disruption. The programme has equipped me with some valuable skills in terms of emotional intelligence, in terms of transformational leadership, and these are quite important ingredients and tools for any organisation that wants to thrive and succeed.” Rabia Wanka, Head of Oil and Gas Transactions, NEXIM Bank. “A lot has been learned. And, specifically, I like the energy. Sincerely, I’ve had other international programmes, but this is with a difference, the faculties that were brought, the way the programme is structured, you know, around organisation and around self. It’s distinct, and I want to recommend it to leaders, to come to TEXEM.” John Tizhe, Executive Director, NPF Microfinance Bank. “Well, I was coming from an environment where agility is the language, it is not strange…to me, but this programme further exposed me more, like, a firsthand information, … with this insight I’ve gotten from here, it’s going to help me to move even more faster…” – Olusola Faleye, MD/CEO, Lagos Building Investment Company Plc (LBIC).

For those who missed this programme, it is not an exaggeration to say that they missed a truly transformative experience. The insights gained were not just theoretical but practical, providing leaders with the tools they need to drive their organisations forward with confidence and agility. As we all know, the ability to adapt and lead in turbulent times is not just a luxury but a necessity for sustainable success. Those who were fortunate enough to attend now carry with them a strategic edge that will undoubtedly set them apart in their respective fields.

Conclusively, in the words of Charles Crawford “There’s always a fascinating dynamic tension between Agility (quick thinking and quick movement NOW!) and Strategy (setting a long-term goal then methodically driving towards it without getting distracted). This course allowed its distinguished participants to think about this tension – and to learn specific skills for getting the balance right.”

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© 2024 Leadership Media Group - All Rights Reserved .

Press Release

Bristol myers squibb to present data at esmo demonstrating ongoing leadership in immuno-oncology and progression of assets from its differentiated research platforms.

Data from proof-of-concept, randomized, Phase 2 RELATIVITY-104 trial exploring the combination of nivolumab, relatlimab (1:1) and chemotherapy as first-line treatment for stage IV or recurrent NSCLC; BMS initiating Phase 3 RELATIVITY-1093 trial

Ten-year follow-up data from CheckMate -067 showed continued durable, long-term survival benefit of Opdivo ® (nivolumab) plus Yervoy ® (ipilimumab) in patients with advanced or metastatic melanoma

Results from several early-phase clinical trials reinforce the strength and diversity of BMS’ oncology portfolio, including novel combinations and modalities, across a wide range of solid tumors

PRINCETON, N.J.--(BUSINESS WIRE)-- Bristol Myers Squibb (NYSE: BMY) today announced the presentation of nearly 60 abstracts of company-sponsored studies, investigator-sponsored studies, and collaborations from across its oncology portfolio and pipeline at the European Society for Medical Oncology (ESMO) Congress 2024 to be held from September 13-17 in Barcelona, Spain.

“Our data at ESMO this year highlight BMS’ enduring impact in oncology and offer insights into our earlier-phase, next-generation assets,” said Samit Hirawat, M.D. , executive vice president, chief medical officer and head of development, Bristol Myers Squibb. “We are proud to continue to expand our oncology leadership and showcase progress within our diversified pipeline, including novel ADCs and protein degraders, to advance the next wave of breakthrough cancer treatments and offer more options for patients across a wide range of tumor types.”

Key data being presented by Bristol Myers Squibb at ESMO Congress 2024 include:

Data supporting our innovative oncology portfolio

• Ten-year follow-up data from the Phase 3 CheckMate –067 trial showed the continued durable, long-term survival benefit of Opdivo ® (nivolumab) plus Yervoy ® (ipilimumab) in patients with advanced or metastatic melanoma. These data represent the longest reported median overall survival from a Phase 3 advanced melanoma trial. (LBA43)
• An update of clinical outcomes from the Phase 3 CheckMate -77T trial evaluating an Opdivo -based perioperative regimen in patients with resectable non-small cell lung cancer (NSCLC) (LBA50)
• Expanded analyses from the CheckMate -9DW trial evaluating Opdivo plus Yervoy vs lenvatinib or sorafenib as first-line (1L) treatment for unresectable hepatocellular carcinoma (uHCC) (965MO)
• Subgroup efficacy and expanded safety data from the Phase 3 CheckMate –8HW trial evaluating Opdivo plus Yervoy as first-line treatment for microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) (541P)
• Updated efficacy and safety results at approximately 15-months of follow up from the Phase 3 CheckMate –67T trial evaluating subcutaneous nivolumab in patients with previously treated advanced or metastatic clear cell renal cell carcinoma (1691P)
• Efficacy and safety data from the randomized Phase 3 KRYSTAL-12 trial evaluating KRAZATI ® (adagrasib) versus docetaxel in patients with pretreated locally advanced or metastatic NSCLC harboring a KRAS G12C mutation and baseline brain metastases (LBA57)

Studies supporting our advancing pipeline

• BMS is initiating the Phase 3 RELATIVITY-1093 trial evaluating the fixed-dose combination of nivolumab and relatlimab (FDC 1:1) plus chemotherapy versus pembrolizumab plus chemotherapy as a first-line treatment for patients with stage IV or recurrent non-squamous NSCLC with tumor cell PD-L1 expression of 1 to 49%, supported by findings from the RELATIVITY-104 trial
• First data from the randomized, Phase 2 CA001-050 trial evaluating BMS-986012, an anti-fucosyl-GM1 monoclonal antibody, in combination with carboplatin, etoposide, and nivolumab as a first-line therapy in newly diagnosed patients with extensive-stage small cell lung cancer: interim analysis (1786O)
• Updated safety and clinical activity from first-in-human Phase 1 trial evaluating the targeted protein degrader BMS-986365, the company’s potential best-in-class oral dual androgen receptor ligand-directed degrader (AR LDD) and antagonist, in heavily pre-treated patients with metastatic castration-resistant prostate cancer (1597MO)
• Three presentations of data evaluating BL-B01D1, a bispecific antibody-drug conjugate (ADC) targeting both EGFR and HER3 being developed in collaboration with SystImmune, Inc., in locally advanced or metastatic biliary tract cancer, locally advanced or metastatic urothelial carcinoma, and locally advanced or metastatic esophageal squamous cell carcinoma (54P, 1959O and 1426P)

Bristol Myers Squibb will host an investor webcast on Saturday, September 14 at 20:00 CEST (2:00 p.m. EDT) to discuss advancements in our cancer pipeline, including key data at ESMO. Company executives will provide an overview at the meeting and address inquiries from investors and analysts.

Investors and the general public are invited to listen to a live webcast at http://investor.bms.com and are urged to register prior to the webcast.

Those unable to register can access the live conference call by dialing in the U.S. toll-free +1 833-816-1116 or international +1 412-317-0705. Materials related to the call will be available at http://investor.bms.com prior to the start of the conference call.

Please see below for Important Safety Information and full Prescribing Information for Opdualag™ (nivolumab and relatlimab-rmbw), Opdivo plus Yervoy, and KRAZATI .

Summary of Presentations:

Select Bristol Myers Squibb studies at the ESMO Congress 2024 include:

All regular abstracts, except late-breaking abstracts, are available on the ESMO Congress 2024 website as of 00:05 CEST on Monday, September 9. All late-breaking abstracts will be available on the ESMO Congress 2024 website at 00:05 CEST on the day of presentation.

Bristol Myers Squibb: Creating a Better Future for People with Cancer

Bristol Myers Squibb is inspired by a single vision — transforming patients’ lives through science. The goal of the company’s cancer research is to deliver medicines that offer each patient a better, healthier life and to make cure a possibility. Building on a legacy across a broad range of cancers that have changed survival expectations for many, Bristol Myers Squibb researchers are exploring new frontiers in personalized medicine and, through innovative digital platforms, are turning data into insights that sharpen their focus. Deep understanding of causal human biology, cutting-edge capabilities and differentiated research programs uniquely position the company to approach cancer from every angle.

Cancer can have a relentless grasp on many parts of a patient’s life, and Bristol Myers Squibb is committed to taking actions to address all aspects of care, from diagnosis to survivorship. As a leader in cancer care, Bristol Myers Squibb is working to empower all people with cancer to have a better future.

OPDIVO INDICATIONS

OPDIVO® (nivolumab), as a single agent, is indicated for the treatment of adult and pediatric patients 12 years and older with unresectable or metastatic melanoma.

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the treatment of adult and pediatric patients 12 years and older with unresectable or metastatic melanoma.

OPDIVO® is indicated for the adjuvant treatment of adult and pediatric patients 12 years and older with completely resected Stage IIB, Stage IIC, Stage III, or Stage IV melanoma.

OPDIVO® (nivolumab), in combination with platinum-doublet chemotherapy, is indicated as neoadjuvant treatment of adult patients with resectable (tumors ≥4 cm or node positive) non-small cell lung cancer (NSCLC).

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the first-line treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors express PD-L1 (≥1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations.

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab) and 2 cycles of platinum-doublet chemotherapy, is indicated for the first-line treatment of adult patients with metastatic or recurrent non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations.

OPDIVO® (nivolumab) is indicated for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) with progression on or after platinum-based chemotherapy. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO.

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the first-line treatment of adult patients with unresectable malignant pleural mesothelioma (MPM).

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the first-line treatment of adult patients with intermediate or poor risk advanced renal cell carcinoma (RCC).

OPDIVO® (nivolumab), in combination with cabozantinib, is indicated for the first-line treatment of adult patients with advanced renal cell carcinoma (RCC).

OPDIVO® (nivolumab) is indicated for the treatment of adult patients with advanced renal cell carcinoma (RCC) who have received prior anti-angiogenic therapy.

OPDIVO® (nivolumab) is indicated for the treatment of adult patients with classical Hodgkin lymphoma (cHL) that has relapsed or progressed after autologous hematopoietic stem cell transplantation (HSCT) and brentuximab vedotin or after 3 or more lines of systemic therapy that includes autologous HSCT. This indication is approved under accelerated approval based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.

OPDIVO® (nivolumab) is indicated for the treatment of adult patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) with disease progression on or after platinum-based therapy.

OPDIVO® (nivolumab) is indicated for the treatment of adult patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy or have disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.

OPDIVO® (nivolumab), as a single agent, is indicated for the adjuvant treatment of adult patients with urothelial carcinoma (UC) who are at high risk of recurrence after undergoing radical resection of UC.

OPDIVO® (nivolumab), in combination with cisplatin and gemcitabine, is indicated as first-line treatment for adult patients with unresectable or metastatic urothelial carcinoma.

OPDIVO® (nivolumab), as a single agent, is indicated for the treatment of adult and pediatric (12 years and older) patients with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (CRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the treatment of adults and pediatric patients 12 years and older with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (CRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the treatment of adult patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in the confirmatory trials.

OPDIVO® (nivolumab) is indicated for the treatment of adult patients with unresectable advanced, recurrent or metastatic esophageal squamous cell carcinoma (ESCC) after prior fluoropyrimidine- and platinum-based chemotherapy.

OPDIVO® (nivolumab) is indicated for the adjuvant treatment of completely resected esophageal or gastroesophageal junction cancer with residual pathologic disease in adult patients who have received neoadjuvant chemoradiotherapy (CRT).

OPDIVO® (nivolumab), in combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the first-line treatment of adult patients with unresectable advanced or metastatic esophageal squamous cell carcinoma (ESCC).

OPDIVO® (nivolumab), in combination with YERVOY® (ipilimumab), is indicated for the first-line treatment of adult patients with unresectable advanced or metastatic esophageal squamous cell carcinoma (ESCC).

OPDIVO® (nivolumab), in combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the treatment of adult patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer, and esophageal adenocarcinoma.

IMPORTANT SAFETY INFORMATION

Severe and Fatal Immune-Mediated Adverse Reactions

Immune-mediated adverse reactions listed herein may not include all possible severe and fatal immune- mediated adverse reactions.

Immune-mediated adverse reactions, which may be severe or fatal, can occur in any organ system or tissue. While immune-mediated adverse reactions usually manifest during treatment, they can also occur after discontinuation of OPDIVO or YERVOY. Early identification and management are essential to ensure safe use of OPDIVO and YERVOY. Monitor for signs and symptoms that may be clinical manifestations of underlying immune-mediated adverse reactions. Evaluate clinical chemistries including liver enzymes, creatinine, adrenocorticotropic hormone (ACTH) level, and thyroid function at baseline and periodically during treatment with OPDIVO and before each dose of YERVOY. In cases of suspected immune-mediated adverse reactions, initiate appropriate workup to exclude alternative etiologies, including infection. Institute medical management promptly, including specialty consultation as appropriate.

Withhold or permanently discontinue OPDIVO and YERVOY depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information). In general, if OPDIVO or YERVOY interruption or discontinuation is required, administer systemic corticosteroid therapy (1 to 2 mg/kg/day prednisone or equivalent) until improvement to Grade 1 or less. Upon improvement to Grade 1 or less, initiate corticosteroid taper and continue to taper over at least 1 month. Consider administration of other systemic immunosuppressants in patients whose immune-mediated adverse reactions are not controlled with corticosteroid therapy. Toxicity management guidelines for adverse reactions that do not necessarily require systemic steroids (e.g., endocrinopathies and dermatologic reactions) are discussed below.

Immune-Mediated Pneumonitis

OPDIVO and YERVOY can cause immune-mediated pneumonitis. The incidence of pneumonitis is higher in patients who have received prior thoracic radiation. In patients receiving OPDIVO monotherapy, immune- mediated pneumonitis occurred in 3.1% (61/1994) of patients, including Grade 4 (<0.1%), Grade 3 (0.9%), and Grade 2 (2.1%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, immune- mediated pneumonitis occurred in 7% (31/456) of patients, including Grade 4 (0.2%), Grade 3 (2.0%), and Grade 2 (4.4%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, immune- mediated pneumonitis occurred in 3.9% (26/666) of patients, including Grade 3 (1.4%) and Grade 2 (2.6%). In NSCLC patients receiving OPDIVO 3 mg/kg every 2 weeks with YERVOY 1 mg/kg every 6 weeks, immune- mediated pneumonitis occurred in 9% (50/576) of patients, including Grade 4 (0.5%), Grade 3 (3.5%), and Grade 2 (4.0%). Four patients (0.7%) died due to pneumonitis.

In Checkmate 205 and 039, pneumonitis, including interstitial lung disease, occurred in 6.0% (16/266) of patients receiving OPDIVO. Immune-mediated pneumonitis occurred in 4.9% (13/266) of patients receiving OPDIVO, including Grade 3 (n=1) and Grade 2 (n=12).

Immune-Mediated Colitis

OPDIVO and YERVOY can cause immune-mediated colitis, which may be fatal. A common symptom included in the definition of colitis was diarrhea. Cytomegalovirus (CMV) infection/reactivation has been reported in patients with corticosteroid-refractory immune-mediated colitis. In cases of corticosteroid-refractory colitis, consider repeating infectious workup to exclude alternative etiologies. In patients receiving OPDIVO monotherapy, immune-mediated colitis occurred in 2.9% (58/1994) of patients, including Grade 3 (1.7%) and Grade 2 (1%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, immune-mediated colitis occurred in 25% (115/456) of patients, including Grade 4 (0.4%), Grade 3 (14%) and Grade 2 (8%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, immune-mediated colitis occurred in 9% (60/666) of patients, including Grade 3 (4.4%) and Grade 2 (3.7%).

Immune-Mediated Hepatitis and Hepatotoxicity

OPDIVO and YERVOY can cause immune-mediated hepatitis. In patients receiving OPDIVO monotherapy, immune-mediated hepatitis occurred in 1.8% (35/1994) of patients, including Grade 4 (0.2%), Grade 3 (1.3%), and Grade 2 (0.4%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, immune-mediated hepatitis occurred in 15% (70/456) of patients, including Grade 4 (2.4%), Grade 3 (11%), and Grade 2 (1.8%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, immune-mediated hepatitis occurred in 7% (48/666) of patients, including Grade 4 (1.2%), Grade 3 (4.9%), and Grade 2 (0.4%).

OPDIVO in combination with cabozantinib can cause hepatic toxicity with higher frequencies of Grade 3 and 4 ALT and AST elevations compared to OPDIVO alone. Consider more frequent monitoring of liver enzymes as compared to when the drugs are administered as single agents. In patients receiving OPDIVO and cabozantinib, Grades 3 and 4 increased ALT or AST were seen in 11% of patients.

Immune-Mediated Endocrinopathies

OPDIVO and YERVOY can cause primary or secondary adrenal insufficiency, immune-mediated hypophysitis, immune-mediated thyroid disorders, and Type 1 diabetes mellitus, which can present with diabetic ketoacidosis. Withhold OPDIVO and YERVOY depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information). For Grade 2 or higher adrenal insufficiency, initiate symptomatic treatment, including hormone replacement as clinically indicated. Hypophysitis can present with acute symptoms associated with mass effect such as headache, photophobia, or visual field defects. Hypophysitis can cause hypopituitarism; initiate hormone replacement as clinically indicated. Thyroiditis can present with or without endocrinopathy. Hypothyroidism can follow hyperthyroidism; initiate hormone replacement or medical management as clinically indicated. Monitor patients for hyperglycemia or other signs and symptoms of diabetes; initiate treatment with insulin as clinically indicated.

In patients receiving OPDIVO monotherapy, adrenal insufficiency occurred in 1% (20/1994), including Grade 3 (0.4%) and Grade 2 (0.6%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, adrenal insufficiency occurred in 8% (35/456), including Grade 4 (0.2%), Grade 3 (2.4%), and Grade 2 (4.2%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, adrenal insufficiency occurred in 7% (48/666) of patients, including Grade 4 (0.3%), Grade 3 (2.5%), and Grade 2 (4.1%). In patients receiving OPDIVO and cabozantinib, adrenal insufficiency occurred in 4.7% (15/320) of patients, including Grade 3 (2.2%) and Grade 2 (1.9%).

In patients receiving OPDIVO monotherapy, hypophysitis occurred in 0.6% (12/1994) of patients, including Grade 3 (0.2%) and Grade 2 (0.3%).

In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, hypophysitis occurred in 9% (42/456), including Grade 3 (2.4%) and Grade 2 (6%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, hypophysitis occurred in 4.4% (29/666) of patients, including Grade 4 (0.3%), Grade 3 (2.4%), and Grade 2 (0.9%).

In patients receiving OPDIVO monotherapy, thyroiditis occurred in 0.6% (12/1994) of patients, including Grade 2 (0.2%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, thyroiditis occurred in 2.7% (22/666) of patients, including Grade 3 (4.5%) and Grade 2 (2.2%).

In patients receiving OPDIVO monotherapy, hyperthyroidism occurred in 2.7% (54/1994) of patients, including Grade 3 (<0.1%) and Grade 2 (1.2%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, hyperthyroidism occurred in 9% (42/456) of patients, including Grade 3 (0.9%) and Grade 2 (4.2%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, hyperthyroidism occurred in 12% (80/666) of patients, including Grade 3 (0.6%) and Grade 2 (4.5%).

In patients receiving OPDIVO monotherapy, hypothyroidism occurred in 8% (163/1994) of patients, including Grade 3 (0.2%) and Grade 2 (4.8%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, hypothyroidism occurred in 20% (91/456) of patients, including Grade 3 (0.4%) and Grade 2 (11%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, hypothyroidism occurred in 18% (122/666) of patients, including Grade 3 (0.6%) and Grade 2 (11%).

In patients receiving OPDIVO monotherapy, diabetes occurred in 0.9% (17/1994) of patients, including Grade 3 (0.4%) and Grade 2 (0.3%), and 2 cases of diabetic ketoacidosis. In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, diabetes occurred in 2.7% (15/666) of patients, including Grade 4 (0.6%), Grade 3 (0.3%), and Grade 2 (0.9%).

Immune-Mediated Nephritis with Renal Dysfunction

OPDIVO and YERVOY can cause immune-mediated nephritis. In patients receiving OPDIVO monotherapy, immune-mediated nephritis and renal dysfunction occurred in 1.2% (23/1994) of patients, including Grade 4 (<0.1%), Grade 3 (0.5%), and Grade 2 (0.6%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, immune-mediated nephritis with renal dysfunction occurred in 4.1% (27/666) of patients, including Grade 4 (0.6%), Grade 3 (1.1%), and Grade 2 (2.2%).

Immune-Mediated Dermatologic Adverse Reactions

OPDIVO can cause immune-mediated rash or dermatitis. Exfoliative dermatitis, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS) has occurred with PD-1/PD-L1 blocking antibodies. Topical emollients and/or topical corticosteroids may be adequate to treat mild to moderate nonexfoliative rashes.

YERVOY can cause immune-mediated rash or dermatitis, including bullous and exfoliative dermatitis, SJS, TEN, and DRESS. Topical emollients and/or topical corticosteroids may be adequate to treat mild to moderate non-bullous/exfoliative rashes.

Withhold or permanently discontinue OPDIVO and YERVOY depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information).

In patients receiving OPDIVO monotherapy, immune-mediated rash occurred in 9% (171/1994) of patients, including Grade 3 (1.1%) and Grade 2 (2.2%). In patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, immune-mediated rash occurred in 28% (127/456) of patients, including Grade 3 (4.8%) and Grade 2 (10%). In patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, immune-mediated rash occurred in 16% (108/666) of patients, including Grade 3 (3.5%) and Grade 2 (4.2%).

Other Immune-Mediated Adverse Reactions

The following clinically significant immune-mediated adverse reactions occurred at an incidence of <1% (unless otherwise noted) in patients who received OPDIVO monotherapy or OPDIVO in combination with YERVOY or were reported with the use of other PD-1/PD-L1 blocking antibodies. Severe or fatal cases have been reported for some of these adverse reactions: cardiac/vascular: myocarditis, pericarditis, vasculitis; nervous system: meningitis, encephalitis, myelitis and demyelination, myasthenic syndrome/myasthenia gravis (including exacerbation), Guillain-Barré syndrome, nerve paresis, autoimmune neuropathy; ocular: uveitis, iritis, and other ocular inflammatory toxicities can occur; gastrointestinal: pancreatitis to include increases in serum amylase and lipase levels, gastritis, duodenitis; musculoskeletal and connective tissue: myositis/polymyositis, rhabdomyolysis, and associated sequelae including renal failure, arthritis, polymyalgia rheumatica; endocrine: hypoparathyroidism; other (hematologic/immune): hemolytic anemia, aplastic anemia, hemophagocytic lymphohistiocytosis (HLH), systemic inflammatory response syndrome, histiocytic necrotizing lymphadenitis (Kikuchi lymphadenitis), sarcoidosis, immune thrombocytopenic purpura, solid organ transplant rejection, other transplant (including corneal graft) rejection.

In addition to the immune-mediated adverse reactions listed above, across clinical trials of YERVOY monotherapy or in combination with OPDIVO, the following clinically significant immune-mediated adverse reactions, some with fatal outcome, occurred in <1% of patients unless otherwise specified: nervous system: autoimmune neuropathy (2%), myasthenic syndrome/myasthenia gravis, motor dysfunction; cardiovascular: angiopathy, temporal arteritis; ocular: blepharitis, episcleritis, orbital myositis, scleritis; gastrointestinal: pancreatitis (1.3%); other (hematologic/immune): conjunctivitis, cytopenias (2.5%), eosinophilia (2.1%), erythema multiforme, hypersensitivity vasculitis, neurosensory hypoacusis, psoriasis.

Some ocular IMAR cases can be associated with retinal detachment. Various grades of visual impairment, including blindness, can occur. If uveitis occurs in combination with other immune-mediated adverse reactions, consider a Vogt-Koyanagi-Harada–like syndrome, which has been observed in patients receiving OPDIVO and YERVOY, as this may require treatment with systemic corticosteroids to reduce the risk of permanent vision loss.

Infusion-Related Reactions

OPDIVO and YERVOY can cause severe infusion-related reactions. Discontinue OPDIVO and YERVOY in patients with severe (Grade 3) or life-threatening (Grade 4) infusion-related reactions. Interrupt or slow the rate of infusion in patients with mild (Grade 1) or moderate (Grade 2) infusion-related reactions. In patients receiving OPDIVO monotherapy as a 60-minute infusion, infusion-related reactions occurred in 6.4% (127/1994) of patients. In a separate trial in which patients received OPDIVO monotherapy as a 60-minute infusion or a 30- minute infusion, infusion-related reactions occurred in 2.2% (8/368) and 2.7% (10/369) of patients, respectively. Additionally, 0.5% (2/368) and 1.4% (5/369) of patients, respectively, experienced adverse reactions within 48 hours of infusion that led to dose delay, permanent discontinuation or withholding of OPDIVO. In melanoma patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, infusion-related reactions occurred in 2.5% (10/407) of patients. In HCC patients receiving OPDIVO 1 mg/kg with YERVOY 3 mg/kg every 3 weeks, infusion-related reactions occurred in 8% (4/49) of patients. In RCC patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, infusion-related reactions occurred in 5.1% (28/547) of patients. In MSI-H/dMMR mCRC patients receiving OPDIVO 3 mg/kg with YERVOY 1 mg/kg every 3 weeks, infusion-related reactions occurred in 4.2% (5/119) of patients. In MPM patients receiving OPDIVO 3 mg/kg every 2 weeks with YERVOY 1 mg/kg every 6 weeks, infusion-related reactions occurred in 12% (37/300) of patients.

Complications of Allogeneic Hematopoietic Stem Cell Transplantation

Fatal and other serious complications can occur in patients who receive allogeneic hematopoietic stem cell transplantation (HSCT) before or after being treated with OPDIVO or YERVOY. Transplant-related complications include hyperacute graft-versus-host-disease (GVHD), acute GVHD, chronic GVHD, hepatic veno-occlusive disease (VOD) after reduced intensity conditioning, and steroid-requiring febrile syndrome (without an identified infectious cause). These complications may occur despite intervening therapy between OPDIVO or YERVOY and allogeneic HSCT.

Follow patients closely for evidence of transplant-related complications and intervene promptly. Consider the benefit versus risks of treatment with OPDIVO and YERVOY prior to or after an allogeneic HSCT.

Embryo-Fetal Toxicity

Based on its mechanism of action and findings from animal studies, OPDIVO and YERVOY can cause fetal harm when administered to a pregnant woman. The effects of YERVOY are likely to be greater during the second and third trimesters of pregnancy. Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with OPDIVO and YERVOY and for at least 5 months after the last dose.

Increased Mortality in Patients with Multiple Myeloma when OPDIVO is Added to a Thalidomide Analogue and Dexamethasone

In randomized clinical trials in patients with multiple myeloma, the addition of OPDIVO to a thalidomide analogue plus dexamethasone resulted in increased mortality. Treatment of patients with multiple myeloma with a PD-1 or PD-L1 blocking antibody in combination with a thalidomide analogue plus dexamethasone is not recommended outside of controlled clinical trials.

There are no data on the presence of OPDIVO or YERVOY in human milk, the effects on the breastfed child, or the effects on milk production. Because of the potential for serious adverse reactions in breastfed children, advise women not to breastfeed during treatment and for 5 months after the last dose.

Serious Adverse Reactions

In Checkmate 037, serious adverse reactions occurred in 41% of patients receiving OPDIVO (n=268). Grade 3 and 4 adverse reactions occurred in 42% of patients receiving OPDIVO. The most frequent Grade 3 and 4 adverse drug reactions reported in 2% to <5% of patients receiving OPDIVO were abdominal pain, hyponatremia, increased aspartate aminotransferase, and increased lipase. In Checkmate 066, serious adverse reactions occurred in 36% of patients receiving OPDIVO (n=206). Grade 3 and 4 adverse reactions occurred in 41% of patients receiving OPDIVO. The most frequent Grade 3 and 4 adverse reactions reported in ≥2% of patients receiving OPDIVO were gamma-glutamyltransferase increase (3.9%) and diarrhea (3.4%). In Checkmate 067, serious adverse reactions (74% and 44%), adverse reactions leading to permanent discontinuation (47% and 18%) or to dosing delays (58% and 36%), and Grade 3 or 4 adverse reactions (72% and 51%) all occurred more frequently in the OPDIVO plus YERVOY arm (n=313) relative to the OPDIVO arm (n=313). The most frequent (≥10%) serious adverse reactions in the OPDIVO plus YERVOY arm and the OPDIVO arm, respectively, were diarrhea (13% and 2.2%), colitis (10% and 1.9%), and pyrexia (10% and 1.0%). In Checkmate 238, serious adverse reactions occurred in 18% of patients receiving OPDIVO (n=452). Grade 3 or 4 adverse reactions occurred in 25% of OPDIVO-treated patients (n=452). The most frequent Grade 3 and 4 adverse reactions reported in ≥2% of OPDIVO-treated patients were diarrhea and increased lipase and amylase. In Checkmate 816, serious adverse reactions occurred in 30% of patients (n=176) who were treated with OPDIVO in combination with platinum-doublet chemotherapy. Serious adverse reactions in >2% included pneumonia and vomiting. No fatal adverse reactions occurred in patients who received OPDIVO in combination with platinum-doublet chemotherapy. In Checkmate 227, serious adverse reactions occurred in 58% of patients (n=576). The most frequent (≥2%) serious adverse reactions were pneumonia, diarrhea/colitis, pneumonitis, hepatitis, pulmonary embolism, adrenal insufficiency, and hypophysitis. Fatal adverse reactions occurred in 1.7% of patients; these included events of pneumonitis (4 patients), myocarditis, acute kidney injury, shock, hyperglycemia, multi-system organ failure, and renal failure. In Checkmate 9LA, serious adverse reactions occurred in 57% of patients (n=358). The most frequent (>2%) serious adverse reactions were pneumonia, diarrhea, febrile neutropenia, anemia, acute kidney injury, musculoskeletal pain, dyspnea, pneumonitis, and respiratory failure. Fatal adverse reactions occurred in 7 (2%) patients, and included hepatic toxicity, acute renal failure, sepsis, pneumonitis, diarrhea with hypokalemia, and massive hemoptysis in the setting of thrombocytopenia. In Checkmate 017 and 057, serious adverse reactions occurred in 46% of patients receiving OPDIVO (n=418). The most frequent serious adverse reactions reported in ≥2% of patients receiving OPDIVO were pneumonia, pulmonary embolism, dyspnea, pyrexia, pleural effusion, pneumonitis, and respiratory failure. In Checkmate 057, fatal adverse reactions occurred; these included events of infection (7 patients, including one case of Pneumocystis jirovecii pneumonia), pulmonary embolism (4 patients), and limbic encephalitis (1 patient). In Checkmate 743, serious adverse reactions occurred in 54% of patients receiving OPDIVO plus YERVOY. The most frequent serious adverse reactions reported in ≥2% of patients were pneumonia, pyrexia, diarrhea, pneumonitis, pleural effusion, dyspnea, acute kidney injury, infusion-related reaction, musculoskeletal pain, and pulmonary embolism. Fatal adverse reactions occurred in 4 (1.3%) patients and included pneumonitis, acute heart failure, sepsis, and encephalitis. In Checkmate 214, serious adverse reactions occurred in 59% of patients receiving OPDIVO plus YERVOY (n=547). The most frequent serious adverse reactions reported in ≥2% of patients were diarrhea, pyrexia, pneumonia, pneumonitis, hypophysitis, acute kidney injury, dyspnea, adrenal insufficiency, and colitis. In Checkmate 9ER, serious adverse reactions occurred in 48% of patients receiving OPDIVO and cabozantinib (n=320). The most frequent serious adverse reactions reported in ≥2% of patients were diarrhea, pneumonia, pneumonitis, pulmonary embolism, urinary tract infection, and hyponatremia. Fatal intestinal perforations occurred in 3 (0.9%) patients. In Checkmate 025, serious adverse reactions occurred in 47% of patients receiving OPDIVO (n=406). The most frequent serious adverse reactions reported in ≥2% of patients were acute kidney injury, pleural effusion, pneumonia, diarrhea, and hypercalcemia. In Checkmate 205 and 039, adverse reactions leading to discontinuation occurred in 7% and dose delays due to adverse reactions occurred in 34% of patients (n=266). Serious adverse reactions occurred in 26% of patients. The most frequent serious adverse reactions reported in ≥1% of patients were pneumonia, infusion-related reaction, pyrexia, colitis or diarrhea, pleural effusion, pneumonitis, and rash.

Eleven patients died from causes other than disease progression: 3 from adverse reactions within 30 days of the last OPDIVO dose, 2 from infection 8 to 9 months after completing OPDIVO, and 6 from complications of allogeneic HSCT. In Checkmate 141, serious adverse reactions occurred in 49% of patients receiving OPDIVO (n=236). The most frequent serious adverse reactions reported in ≥2% of patients receiving OPDIVO were pneumonia, dyspnea, respiratory failure, respiratory tract infection, and sepsis. In Checkmate 275, serious adverse reactions occurred in 54% of patients receiving OPDIVO (n=270). The most frequent serious adverse reactions reported in ≥2% of patients receiving OPDIVO were urinary tract infection, sepsis, diarrhea, small intestine obstruction, and general physical health deterioration. In Checkmate 274, serious adverse reactions occurred in 30% of patients receiving OPDIVO (n=351). The most frequent serious adverse reaction reported in ≥2% of patients receiving OPDIVO was urinary tract infection. Fatal adverse reactions occurred in 1% of patients; these included events of pneumonitis (0.6%). In Checkmate 901, serious adverse reactions occurred in 48% of patients receiving OPDIVO in combination with chemotherapy. The most frequent serious adverse reactions reporting in ≥2% of patients who received OPDIVO with chemotherapy were urinary tract infection (4.9%), acute kidney injury (4.3%), anemia (3%), pulmonary embolism (2.6%), sepsis (2.3%), and platelet count decreased (2.3%). Fatal adverse reactions occurred in 3.6% of patients who received OPDIVO in combination with chemotherapy; these included sepsis (1%). OPDIVO and/or chemotherapy were discontinued in 30% of patients and were delayed in 67% of patients for an adverse reaction. In Checkmate 142 in MSI-H/dMMR mCRC patients receiving OPDIVO with YERVOY (n=119), serious adverse reactions occurred in 47% of patients. The most frequent serious adverse reactions reported in ≥2% of patients were colitis/diarrhea, hepatic events, abdominal pain, acute kidney injury, pyrexia, and dehydration. In Checkmate 040, serious adverse reactions occurred in 59% of patients receiving OPDIVO with YERVOY (n=49). Serious adverse reactions reported in ≥4% of patients were pyrexia, diarrhea, anemia, increased AST, adrenal insufficiency, ascites, esophageal varices hemorrhage, hyponatremia, increased blood bilirubin, and pneumonitis. In Attraction-3, serious adverse reactions occurred in 38% of patients receiving OPDIVO (n=209). Serious adverse reactions reported in ≥2% of patients who received OPDIVO were pneumonia, esophageal fistula, interstitial lung disease, and pyrexia. The following fatal adverse reactions occurred in patients who received OPDIVO: interstitial lung disease or pneumonitis (1.4%), pneumonia (1.0%), septic shock (0.5%), esophageal fistula (0.5%), gastrointestinal hemorrhage (0.5%), pulmonary embolism (0.5%), and sudden death (0.5%). In Checkmate 577, serious adverse reactions occurred in 33% of patients receiving OPDIVO (n=532). A serious adverse reaction reported in ≥2% of patients who received OPDIVO was pneumonitis. A fatal reaction of myocardial infarction occurred in one patient who received OPDIVO. In Checkmate 648, serious adverse reactions occurred in 62% of patients receiving OPDIVO in combination with chemotherapy (n=310). The most frequent serious adverse reactions reported in ≥2% of patients who received OPDIVO with chemotherapy were pneumonia (11%), dysphagia (7%), esophageal stenosis (2.9%), acute kidney injury (2.9%), and pyrexia (2.3%). Fatal adverse reactions occurred in 5 (1.6%) patients who received OPDIVO in combination with chemotherapy; these included pneumonitis, pneumatosis intestinalis, pneumonia, and acute kidney injury. In Checkmate 648, serious adverse reactions occurred in 69% of patients receiving OPDIVO in combination with YERVOY (n=322). The most frequent serious adverse reactions reported in ≥2% who received OPDIVO in combination with YERVOY were pneumonia (10%), pyrexia (4.3%), pneumonitis (4.0%), aspiration pneumonia (3.7%), dysphagia (3.7%), hepatic function abnormal (2.8%), decreased appetite (2.8%), adrenal insufficiency (2.5%), and dehydration (2.5%). Fatal adverse reactions occurred in 5 (1.6%) patients who received OPDIVO in combination with YERVOY; these included pneumonitis, interstitial lung disease, pulmonary embolism, and acute respiratory distress syndrome. In Checkmate 649, serious adverse reactions occurred in 52% of patients treated with OPDIVO in combination with chemotherapy (n=782). The most frequent serious adverse reactions reported in ≥2% of patients treated with OPDIVO in combination with chemotherapy were vomiting (3.7%), pneumonia (3.6%), anemia (3.6%), pyrexia (2.8%), diarrhea (2.7%), febrile neutropenia (2.6%), and pneumonitis (2.4%). Fatal adverse reactions occurred in 16 (2.0%) patients who were treated with OPDIVO in combination with chemotherapy; these included pneumonitis (4 patients), febrile neutropenia (2 patients), stroke (2 patients), gastrointestinal toxicity, intestinal mucositis, septic shock, pneumonia, infection, gastrointestinal bleeding, mesenteric vessel thrombosis, and disseminated intravascular coagulation. In Checkmate 76K, serious adverse reactions occurred in 18% of patients receiving OPDIVO (n=524). Adverse reactions which resulted in permanent discontinuation of OPDIVO in >1% of patients included arthralgia (1.7%), rash (1.7%), and diarrhea (1.1%). A fatal adverse reaction occurred in 1 (0.2%) patient (heart failure and acute kidney injury). The most frequent Grade 3-4 lab abnormalities reported in ≥1% of OPDIVO-treated patients were increased lipase (2.9%), increased AST (2.2%), increased ALT (2.1%), lymphopenia (1.1%), and decreased potassium (1.0%).

Common Adverse Reactions

In Checkmate 037, the most common adverse reaction (≥20%) reported with OPDIVO (n=268) was rash (21%). In Checkmate 066, the most common adverse reactions (≥20%) reported with OPDIVO (n=206) vs dacarbazine (n=205) were fatigue (49% vs 39%), musculoskeletal pain (32% vs 25%), rash (28% vs 12%), and pruritus (23% vs 12%). In Checkmate 067, the most common (≥20%) adverse reactions in the OPDIVO plus YERVOY arm (n=313) were fatigue (62%), diarrhea (54%), rash (53%), nausea (44%), pyrexia (40%), pruritus (39%), musculoskeletal pain (32%), vomiting (31%), decreased appetite (29%), cough (27%), headache (26%),dyspnea (24%), upper respiratory tract infection (23%), arthralgia (21%), and increased transaminases (25%). In Checkmate 067, the most common (≥20%) adverse reactions in the OPDIVO arm (n=313) were fatigue (59%), rash (40%), musculoskeletal pain (42%), diarrhea (36%), nausea (30%), cough (28%), pruritus (27%), upper respiratory tract infection (22%), decreased appetite (22%), headache (22%), constipation (21%), arthralgia (21%), and vomiting (20%). In Checkmate 238, the most common adverse reactions (≥20%) reported in OPDIVO-treated patients (n=452) vs ipilimumab-treated patients (n=453) were fatigue (57% vs 55%), diarrhea (37% vs 55%), rash (35% vs 47%), musculoskeletal pain (32% vs 27%), pruritus (28% vs 37%), headache (23% vs 31%), nausea (23% vs 28%), upper respiratory infection (22% vs 15%), and abdominal pain (21% vs 23%). The most common immune-mediated adverse reactions were rash (16%), diarrhea/colitis (6%), and hepatitis (3%). In Checkmate 816, the most common (>20%) adverse reactions in the OPDIVO plus chemotherapy arm (n=176) were nausea (38%), constipation (34%), fatigue (26%), decreased appetite (20%), and rash (20%). In Checkmate 227, the most common (≥20%) adverse reactions were fatigue (44%), rash (34%), decreased appetite (31%), musculoskeletal pain (27%), diarrhea/colitis (26%), dyspnea (26%), cough (23%), hepatitis (21%), nausea (21%), and pruritus (21%). In Checkmate 9LA, the most common (>20%) adverse reactions were fatigue (49%), musculoskeletal pain (39%), nausea (32%), diarrhea (31%), rash (30%), decreased appetite (28%), constipation (21%), and pruritus (21%). In Checkmate 017 and 057, the most common adverse reactions (≥20%) in patients receiving OPDIVO (n=418) were fatigue, musculoskeletal pain, cough, dyspnea, and decreased appetite. In Checkmate 743, the most common adverse reactions (≥20%) in patients receiving OPDIVO plus YERVOY were fatigue (43%), musculoskeletal pain (38%), rash (34%), diarrhea (32%), dyspnea (27%), nausea (24%), decreased appetite (24%), cough (23%), and pruritus (21%). In Checkmate 214, the most common adverse reactions (≥20%) reported in patients treated with OPDIVO plus YERVOY (n=547) were fatigue (58%), rash (39%), diarrhea (38%), musculoskeletal pain (37%), pruritus (33%), nausea (30%), cough (28%), pyrexia (25%), arthralgia (23%), decreased appetite (21%), dyspnea (20%), and vomiting (20%). In Checkmate 9ER, the most common adverse reactions (≥20%) in patients receiving OPDIVO and cabozantinib (n=320) were diarrhea (64%), fatigue (51%), hepatotoxicity (44%), palmar-plantar erythrodysaesthesia syndrome (40%), stomatitis (37%), rash (36%), hypertension (36%), hypothyroidism (34%), musculoskeletal pain (33%), decreased appetite (28%), nausea (27%), dysgeusia (24%), abdominal pain (22%), cough (20%) and upper respiratory tract infection (20%). In Checkmate 025, the most common adverse reactions (≥20%) reported in patients receiving OPDIVO (n=406) vs everolimus (n=397) were fatigue (56% vs 57%), cough (34% vs 38%), nausea (28% vs 29%), rash (28% vs 36%), dyspnea (27% vs 31%), diarrhea (25% vs 32%), constipation (23% vs 18%), decreased appetite (23% vs 30%), back pain (21% vs 16%), and arthralgia (20% vs 14%). In Checkmate 205 and 039, the most common adverse reactions (≥20%) reported in patients receiving OPDIVO (n=266) were upper respiratory tract infection (44%), fatigue (39%), cough (36%), diarrhea (33%), pyrexia (29%), musculoskeletal pain (26%), rash (24%), nausea (20%) and pruritus (20%). In Checkmate 141, the most common adverse reactions (≥10%) in patients receiving OPDIVO (n=236) were cough (14%) and dyspnea (14%) at a higher incidence than investigator’s choice. In Checkmate 275, the most common adverse reactions (≥20%) reported in patients receiving OPDIVO (n=270) were fatigue (46%), musculoskeletal pain (30%), nausea (22%), and decreased appetite (22%). In Checkmate 274, the most common adverse reactions (≥20%) reported in patients receiving OPDIVO (n=351) were rash (36%), fatigue (36%), diarrhea (30%), pruritus (30%), musculoskeletal pain (28%), and urinary tract infection (22%).In Checkmate 901, the most common adverse reactions (≥20%) were nausea, fatigue, musculoskeletal pain, constipation, decreased appetite, rash, vomiting, and peripheral neuropathy. In Checkmate 142 in MSI-H/dMMR mCRC patients receiving OPDIVO as a single agent (n=74), the most common adverse reactions (≥20%) were fatigue (54%), diarrhea (43%), abdominal pain (34%), nausea (34%), vomiting (28%), musculoskeletal pain (28%), cough (26%), pyrexia (24%), rash (23%), constipation (20%), and upper respiratory tract infection (20%). In Checkmate 142 in MSI-H/dMMR mCRC patients receiving OPDIVO with YERVOY (n=119), the most common adverse reactions (≥20%) were fatigue (49%), diarrhea (45%), pyrexia (36%), musculoskeletal pain (36%), abdominal pain (30%), pruritus (28%), nausea (26%), rash (25%), decreased appetite (20%), and vomiting (20%). In Checkmate 040, the most common adverse reactions (≥20%) in patients receiving OPDIVO with YERVOY (n=49), were rash (53%), pruritus (53%), musculoskeletal pain (41%), diarrhea (39%), cough (37%), decreased appetite (35%), fatigue (27%), pyrexia (27%), abdominal pain (22%), headache (22%), nausea (20%), dizziness (20%), hypothyroidism (20%), and weight decreased (20%). In Attraction-3, the most common adverse reactions (≥20%) in OPDIVO-treated patients (n=209) were rash (22%) and decreased appetite (21%). In Checkmate 577, the most common adverse reactions (≥20%) in patients receiving OPDIVO (n=532) were fatigue (34%), diarrhea (29%), nausea (23%), rash (21%), musculoskeletal pain (21%), and cough (20%). In Checkmate 648, the most common adverse reactions (≥20%) in patients treated with OPDIVO in combination with chemotherapy (n=310) were nausea (65%), decreased appetite (51%), fatigue (47%), constipation (44%), stomatitis (44%), diarrhea (29%), and vomiting (23%). In Checkmate 648, the most common adverse reactions reported in ≥20% of patients treated with OPDIVO in combination with YERVOY were rash (31%), fatigue (28%), pyrexia (23%), nausea (22%), diarrhea (22%), and constipation (20%). In Checkmate 649, the most common adverse reactions (≥20%) in patients treated with OPDIVO in combination with chemotherapy (n=782) were peripheral neuropathy (53%), nausea (48%), fatigue (44%), diarrhea (39%), vomiting (31%), decreased appetite (29%), abdominal pain (27%), constipation (25%), and musculoskeletal pain (20%). In Checkmate 76K, the most common adverse reactions (≥20%) reported with OPDIVO (n=524) were fatigue (36%), musculoskeletal pain (30%), rash (28%), diarrhea (23%) and pruritis (20%).

Please see U.S. Full Prescribing Information for OPDIVO and YERVOY .

Clinical Trials and Patient Populations

Checkmate 227—previously untreated metastatic non-small cell lung cancer, in combination with YERVOY; Checkmate 9LA–previously untreated recurrent or metastatic non-small cell lung cancer in combination with YERVOY and 2 cycles of platinum-doublet chemotherapy by histology; Checkmate 649–previously untreated advanced or metastatic gastric cancer, gastroesophageal junction and esophageal adenocarcinoma; Checkmate 577–adjuvant treatment of esophageal or gastroesophageal junction cancer; Checkmate 238– adjuvant treatment of patients with completely resected Stage III or Stage IV melanoma; Checkmate 76K– adjuvant treatment of patients 12 years of age and older with completely resected Stage IIB or Stage IIC melanoma; Checkmate 274–adjuvant treatment of urothelial carcinoma; Checkmate 275–previously treated advanced or metastatic urothelial carcinoma; Checkmate 142–MSI-H or dMMR metastatic colorectal cancer, as a single agent or in combination with YERVOY; Checkmate 142–MSI-H or dMMR metastatic colorectal cancer, as a single agent or in combination with YERVOY; Attraction-3–esophageal squamous cell carcinoma; Checkmate 648—previously untreated, unresectable advanced recurrent or metastatic esophageal squamous cell carcinoma; Checkmate 648—previously untreated, unresectable advanced recurrent or metastatic esophageal squamous cell carcinoma; Checkmate 040–hepatocellular carcinoma, in combination with YERVOY; Checkmate 743–previously untreated unresectable malignant pleural mesothelioma, in combination with YERVOY; Checkmate 037–previously treated metastatic melanoma; Checkmate 066—previously untreated metastatic melanoma; Checkmate 067–previously untreated metastatic melanoma, as a single agent or in combination with YERVOY; Checkmate 017–second-line treatment of metastatic squamous non-small cell lung cancer; Checkmate 057–second-line treatment of metastatic non-squamous non-small cell lung cancer; Checkmate 816–neoadjuvant non-small cell lung cancer, in combination with platinum-doublet chemotherapy; Checkmate 901–Adult patients with unresectable or metastatic urothelial carcinoma; Checkmate 141–recurrent or metastatic squamous cell carcinoma of the head and neck; Checkmate 025–previously treated renal cell carcinoma; Checkmate 214–previously untreated renal cell carcinoma, in combination with YERVOY; Checkmate 9ER–previously untreated renal cell carcinoma, in combination with cabozantinib; Checkmate 205/039–classical Hodgkin lymphoma

OPDUALAG INDICATION

Opdualag™ (nivolumab and relatlimab-rmbw) is indicated for the treatment of adult and pediatric patients 12 years of age or older with unresectable or metastatic melanoma.

Immune-mediated adverse reactions (IMARs) listed herein may not include all possible severe and fatal immune-mediated adverse reactions.

IMARs which may be severe or fatal, can occur in any organ system or tissue. IMARs can occur at any time after starting treatment with a LAG-3 and PD-1/PD-L1 blocking antibodies. While IMARs usually manifest during treatment, they can also occur after discontinuation of Opdualag. Early identification and management of IMARs are essential to ensure safe use. Monitor patients closely for symptoms and signs that may be clinical manifestations of underlying IMARs. Evaluate clinical chemistries including liver enzymes, creatinine, and thyroid function at baseline and periodically during treatment. In cases of suspected IMARs, initiate appropriate workup to exclude alternative etiologies, including infection. Institute medical management promptly, including specialty consultation as appropriate.

Withhold or permanently discontinue Opdualag depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information). In general, if Opdualag requires interruption or discontinuation, administer systemic corticosteroid therapy (1 to 2 mg/kg/day prednisone or equivalent) until improvement to Grade 1 or less. Upon improvement to Grade 1 or less, initiate corticosteroid taper and continue to taper over at least 1 month. Consider administration of other systemic immunosuppressants in patients whose IMARs are not controlled with corticosteroid therapy. Toxicity management guidelines for adverse reactions that do not necessarily require systemic steroids (e.g., endocrinopathies and dermatologic reactions) are discussed below.

Opdualag can cause immune-mediated pneumonitis, which may be fatal. In patients treated with other PD- 1/PD-L1 blocking antibodies, the incidence of pneumonitis is higher in patients who have received prior thoracic radiation. Immune-mediated pneumonitis occurred in 3.7% (13/355) of patients receiving Opdualag, including Grade 3 (0.6%), and Grade 2 (2.3%) adverse reactions. Pneumonitis led to permanent discontinuation of Opdualag in 0.8% and withholding of Opdualag in 1.4% of patients.

Opdualag can cause immune-mediated colitis, defined as requiring use of corticosteroids and no clear alternate etiology. A common symptom included in the definition of colitis was diarrhea. Cytomegalovirus infection/reactivation has been reported in patients with corticosteroid-refractory immune-mediated colitis. In cases of corticosteroid-refractory colitis, consider repeating infectious workup to exclude alternative etiologies.

Immune-mediated diarrhea or colitis occurred in 7% (24/355) of patients receiving Opdualag, including Grade 3 (1.1%) and Grade 2 (4.5%) adverse reactions. Colitis led to permanent discontinuation of Opdualag in 2% and withholding of Opdualag in 2.8% of patients.

Immune-Mediated Hepatitis

Opdualag can cause immune-mediated hepatitis, defined as requiring the use of corticosteroids and no clear alternate etiology.

Immune-mediated hepatitis occurred in 6% (20/355) of patients receiving Opdualag, including Grade 4 (0.6%), Grade 3 (3.4%), and Grade 2 (1.4%) adverse reactions. Hepatitis led to permanent discontinuation of Opdualag in 1.7% and withholding of Opdualag in 2.3% of patients.

Opdualag can cause primary or secondary adrenal insufficiency, hypophysitis, thyroid disorders, and Type 1 diabetes mellitus, which can be present with diabetic ketoacidosis. Withhold or permanently discontinue Opdualag depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information).

For Grade 2 or higher adrenal insufficiency, initiate symptomatic treatment, including hormone replacement as clinically indicated. In patients receiving Opdualag, adrenal insufficiency occurred in 4.2% (15/355) of patients receiving Opdualag, including Grade 3 (1.4%) and Grade 2 (2.5%) adverse reactions. Adrenal insufficiency led to permanent discontinuation of Opdualag in 1.1% and withholding of Opdualag in 0.8% of patients.

Hypophysitis can present with acute symptoms associated with mass effect such as headache, photophobia, or visual field defects. Hypophysitis can cause hypopituitarism; initiate hormone replacement as clinically indicated. Hypophysitis occurred in 2.5% (9/355) of patients receiving Opdualag, including Grade 3 (0.3%) and Grade 2 (1.4%) adverse reactions. Hypophysitis led to permanent discontinuation of Opdualag in 0.3% and withholding of Opdualag in 0.6% of patients.

Thyroiditis can present with or without endocrinopathy. Hypothyroidism can follow hyperthyroidism; initiate hormone replacement or medical management as clinically indicated. Thyroiditis occurred in 2.8% (10/355) of patients receiving Opdualag, including Grade 2 (1.1%) adverse reactions. Thyroiditis did not lead to permanent discontinuation of Opdualag. Thyroiditis led to withholding of Opdualag in 0.3% of patients. Hyperthyroidism occurred in 6% (22/355) of patients receiving Opdualag, including Grade 2 (1.4%) adverse reactions. Hyperthyroidism did not lead to permanent discontinuation of Opdualag. Hyperthyroidism led to withholding of Opdualag in 0.3% of patients. Hypothyroidism occurred in 17% (59/355) of patients receiving Opdualag, including Grade 2 (11%) adverse reactions. Hypothyroidism led to the permanent discontinuation of Opdualag in 0.3% and withholding of Opdualag in 2.5% of patients.

Monitor patients for hyperglycemia or other signs and symptoms of diabetes; initiate treatment with insulin as clinically indicated. Diabetes occurred in 0.3% (1/355) of patients receiving Opdualag, a Grade 3 (0.3%) adverse reaction, and no cases of diabetic ketoacidosis. Diabetes did not lead to the permanent discontinuation or withholding of Opdualag in any patient.

Opdualag can cause immune-mediated nephritis, which is defined as requiring use of steroids and no clear etiology. In patients receiving Opdualag, immune-mediated nephritis and renal dysfunction occurred in 2% (7/355) of patients, including Grade 3 (1.1%) and Grade 2 (0.8%) adverse reactions. Immune-mediated nephritis and renal dysfunction led to permanent discontinuation of Opdualag in 0.8% and withholding of Opdualag in 0.6% of patients.

Withhold or permanently discontinue Opdualag depending on severity (please see section 2 Dosage and Administration in the accompanying Full Prescribing Information).

Opdualag can cause immune-mediated rash or dermatitis, defined as requiring use of steroids and no clear alternate etiology. Exfoliative dermatitis, including Stevens-Johnson syndrome, toxic epidermal necrolysis, and Drug Rash with eosinophilia and systemic symptoms has occurred with PD-1/L-1 blocking antibodies. Topical emollients and/or topical corticosteroids may be adequate to treat mild to moderate non-exfoliative rashes.

Immune-mediated rash occurred in 9% (33/355) of patients, including Grade 3 (0.6%) and Grade 2 (3.4%) adverse reactions. Immune-mediated rash did not lead to permanent discontinuation of Opdualag. Immune- mediated rash led to withholding of Opdualag in 1.4% of patients.

Immune-Mediated Myocarditis

Opdualag can cause immune-mediated myocarditis, which is defined as requiring use of steroids and no clear alternate etiology. The diagnosis of immune-mediated myocarditis requires a high index of suspicion. Patients with cardiac or cardio-pulmonary symptoms should be assessed for potential myocarditis. If myocarditis is suspected, withhold dose, promptly initiate high dose steroids (prednisone or methylprednisolone 1 to 2 mg/kg/day) and promptly arrange cardiology consultation with diagnostic workup. If clinically confirmed, permanently discontinue Opdualag for Grade 2-4 myocarditis.

Myocarditis occurred in 1.7% (6/355) of patients receiving Opdualag, including Grade 3 (0.6%), and Grade 2 (1.1%) adverse reactions. Myocarditis led to permanent discontinuation of Opdualag in 1.7% of patients.

The following clinically significant IMARs occurred at an incidence of <1% (unless otherwise noted) in patients who received Opdualag or were reported with the use of other PD-1/PD-L1 blocking antibodies. Severe or fatal cases have been reported for some of these adverse reactions: Cardiac/Vascular: pericarditis, vasculitis; Nervous System: meningitis, encephalitis, myelitis and demyelination, myasthenic syndrome/myasthenia gravis (including exacerbation), Guillain-Barré syndrome, nerve paresis, autoimmune neuropathy; Ocular: uveitis, iritis, and other ocular inflammatory toxicities can occur. Some cases can be associated with retinal detachment. Various grades of visual impairment, including blindness, can occur. If uveitis occurs in combination with other IMARs, consider a Vogt-Koyanagi-Harada–like syndrome, as this may require treatment with systemic steroids to reduce the risk of permanent vision loss; Gastrointestinal: pancreatitis including increases in serum amylase and lipase levels, gastritis, duodenitis; Musculoskeletal and Connective Tissue: myositis/polymyositis, rhabdomyolysis (and associated sequelae including renal failure), arthritis, polymyalgia rheumatica; Endocrine: hypoparathyroidism; Other (Hematologic/Immune): hemolytic anemia, aplastic anemia, hemophagocytic lymphohistiocytosis, systemic inflammatory response syndrome, histiocytic necrotizing lymphadenitis (Kikuchi lymphadenitis), sarcoidosis, immune thrombocytopenic purpura, solid organ transplant rejection, other transplant (including corneal graft) rejection.

Opdualag can cause severe infusion-related reactions. Discontinue Opdualag in patients with severe or life- threatening infusion-related reactions. Interrupt or slow the rate of infusion in patients with mild to moderate infusion-related reactions. In patients who received Opdualag as a 60-minute intravenous infusion, infusion-related reactions occurred in 7% (23/355) of patients.

Complications of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Fatal and other serious complications can occur in patients who receive allogeneic hematopoietic stem cell transplantation (HSCT) before or after being treated with a PD-1/PD-L1 receptor blocking antibody. Transplant- related complications include hyperacute graft-versus-host disease (GVHD), acute GVHD, chronic GVHD, hepatic veno-occlusive disease after reduced intensity conditioning, and steroid-requiring febrile syndrome (without an identified infectious cause). These complications may occur despite intervening therapy between PD-1/PD-L1 blockade and allogeneic HSCT.

Follow patients closely for evidence of transplant-related complications and intervene promptly. Consider the benefit versus risks of treatment with a PD-1/PD-L1 receptor blocking antibody prior to or after an allogeneic HSCT.

Based on its mechanism of action and data from animal studies, Opdualag can cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with Opdualag and for at least 5 months after the last dose of Opdualag.

There are no data on the presence of Opdualag in human milk, the effects on the breastfed child, or the effect on milk production. Because nivolumab and relatlimab may be excreted in human milk and because of the potential for serious adverse reactions in a breastfed child, advise patients not to breastfeed during treatment with Opdualag and for at least 5 months after the last dose.

In Relativity-047, fatal adverse reactions occurred in 3 (0.8%) patients who were treated with Opdualag; these included hemophagocytic lymphohistiocytosis, acute edema of the lung, and pneumonitis. Serious adverse reactions occurred in 36% of patients treated with Opdualag. The most frequent serious adverse reactions reported in ≥1% of patients treated with Opdualag were adrenal insufficiency (1.4%), anemia (1.4%), colitis (1.4%), pneumonia (1.4%), acute myocardial infarction (1.1%), back pain (1.1%), diarrhea (1.1%), myocarditis (1.1%), and pneumonitis (1.1%).

Common Adverse Reactions and Laboratory Abnormalities

The most common adverse reactions reported in ≥20% of the patients treated with Opdualag were musculoskeletal pain (45%), fatigue (39%), rash (28%), pruritus (25%), and diarrhea (24%).

The most common laboratory abnormalities that occurred in ≥20% of patients treated with Opdualag were decreased hemoglobin (37%), decreased lymphocytes (32%), increased AST (30%), increased ALT (26%), and decreased sodium (24%).

Please see U.S. Full Prescribing Information for Opdualag .

KRAZATI INDICATIONS

KRAZATI in combination with cetuximab is indicated for the treatment of adult patients with KRAS G12C -mutated locally advanced or metastatic colorectal cancer (CRC), as determined by an FDA-approved test, who have received prior treatment with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy.

KRAZATI , as a single agent, is indicated for the treatment of adult patients with KRAS G12C -mutated locally advanced or metastatic non-small cell lung cancer (NSCLC), as determined by an FDA-approved test, who have received at least one prior systemic therapy.

These indications are approved under accelerated approval based on objective response rate (ORR) and duration of response (DOR). Continued approval for these indications may be contingent upon verification and description of a clinical benefit in confirmatory trials.

WARNINGS AND PRECAUTIONS

Gastrointestinal Adverse Reactions

• KRAZATI can cause severe gastrointestinal adverse reactions.
• Monitor and manage patients using supportive care, including antidiarrheals, antiemetics, or fluid replacement, as indicated. Withhold, reduce the dose, or permanently discontinue KRAZATI based on severity.

QTc Interval Prolongation

• KRAZATI can cause QTc interval prolongation, which can increase the risk for ventricular tachyarrhythmias (e.g., torsades de pointes) or sudden death.
• Avoid concomitant use of KRAZATI with other products with a known potential to prolong the QTc interval. Avoid use of KRAZATI in patients with congenital long QT syndrome and in patients with concurrent QTc prolongation.
• Monitor ECGs and electrolytes, particularly potassium and magnesium, prior to starting KRAZATI, during concomitant use, and as clinically indicated in patients with congestive heart failure, bradyarrhythmias, electrolyte abnormalities, and in patients who are unable to avoid concomitant medications that are known to prolong the QT interval. Correct electrolyte abnormalities. Withhold, reduce the dose, or permanently discontinue KRAZATI, depending on severity.

Hepatotoxicity

• KRAZATI can cause hepatotoxicity, which may lead to drug-induced liver injury and hepatitis.
• Monitor liver laboratory tests (AST, ALT, alkaline phosphatase, and total bilirubin) prior to the start of KRAZATI, and monthly for 3 months or as clinically indicated, with more frequent testing in patients who develop transaminase elevations. Reduce the dose, withhold, or permanently discontinue KRAZATI based on severity.

Interstitial Lung Disease/Pneumonitis

• KRAZATI can cause interstitial lung disease (ILD)/pneumonitis, which can be fatal.
• Monitor patients for new or worsening respiratory symptoms indicative of ILD/pneumonitis (e.g., dyspnea, cough, fever) during treatment with KRAZATI. Withhold KRAZATI in patients with suspected ILD/pneumonitis and permanently discontinue KRAZATI if no other potential causes of ILD/pneumonitis are identified.

ADVERSE REACTIONS

• Serious adverse reactions occurred in 57% of 116 patients who received adagrasib in NSCLC patients. The most common adverse reactions in NSCLC patients (≥20%) were diarrhea, nausea, fatigue, vomiting, musculoskeletal pain, hepatotoxicity, renal impairment, dyspnea, edema, decreased appetite, cough, pneumonia, dizziness, constipation, abdominal pain, and QTc interval prolongation.
• Serious adverse reactions occurred in 30% of 94 patients who received adagrasib in combination with cetuximab. The most common adverse reactions in CRC patients (≥20%) were rash, nausea, diarrhea, vomiting, fatigue, musculoskeletal pain, hepatotoxicity, headache, dry skin, abdominal pain, decreased appetite, edema, anemia, dizziness, cough, constipation, and peripheral neuropathy.

DRUG INTERACTIONS

• Strong CYP3A4 Inducers: Avoid concomitant use.
• Strong CYP3A4 Inhibitors: Avoid concomitant use until adagrasib concentrations have reached steady state (after ~8 days).
• Sensitive CYP3A4 Substrates: Avoid concomitant use with sensitive CYP3A4 substrates.
• Sensitive CYP2C9 or CYP2D6 Substrates or P-gp Substrates: Avoid concomitant use with sensitive CYP2C9 or CYP2D6 substrates or P-gp substrates where minimal concentration changes may lead to serious adverse reactions.
• Drugs That Prolong QT Interval: Avoid concomitant use with KRAZATI.

Please see Drug Interactions Section of the Full Prescribing Information for additional information.

USE IN SPECIFIC POPULATIONS

Females and Males of Reproductive Potential

• Infertility: Based on findings from animal studies, KRAZATI may impair fertility in females and males of reproductive potential.
• Advise not to breastfeed.

Please see U.S. Full Prescribing Information for KRAZATI .

About the Bristol Myers Squibb and Ono Pharmaceutical Collaboration

In 2011, through a collaboration agreement with Ono Pharmaceutical Co., Bristol Myers Squibb expanded its territorial rights to develop and commercialize Opdivo globally, except in Japan, South Korea and Taiwan, where Ono had retained all rights to the compound at the time. On July 23, 2014, Ono and Bristol Myers Squibb further expanded the companies’ strategic collaboration agreement to jointly develop and commercialize multiple immunotherapies – as single agents and combination regimens – for patients with cancer in Japan, South Korea and Taiwan.

About Bristol Myers Squibb

Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. For more information about Bristol Myers Squibb, visit us at BMS.com or follow us on LinkedIn , Twitter , YouTube , Facebook and Instagram .

Cautionary Statement Regarding Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 regarding, among other things, the research, development and commercialization of pharmaceutical products. All statements that are not statements of historical facts are, or may be deemed to be, forward-looking statements. Such forward-looking statements are based on current expectations and projections about our future financial results, goals, plans and objectives and involve inherent risks, assumptions and uncertainties, including internal or external factors that could delay, divert or change any of them in the next several years, that are difficult to predict, may be beyond our control and could cause our future financial results, goals, plans and objectives to differ materially from those expressed in, or implied by, the statements. These risks, assumptions, uncertainties and other factors include, among others, that future study results may not be consistent with the results to date, that the treatments and combination treatments described in this release may not receive regulatory approval for the indications described in this release, any marketing approvals, if granted, may have significant limitations on their use, and, if approved, whether such treatments and combination treatments for such indications will be commercially successful. No forward-looking statement can be guaranteed. Forward-looking statements in this press release should be evaluated together with the many risks and uncertainties that affect Bristol Myers Squibb’s business and market, particularly those identified in the cautionary statement and risk factors discussion in Bristol Myers Squibb’s Annual Report on Form 10-K for the year ended December 31, 2023, as updated by our subsequent Quarterly Reports on Form 10-Q, Current Reports on Form 8-K and other filings with the Securities and Exchange Commission. The forward-looking statements included in this document are made only as of the date of this document and except as otherwise required by applicable law, Bristol Myers Squibb undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events, changed circumstances or otherwise.

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Everything Apple announced, from the AI-powered iPhone 16 to AirPods that double as ‘clinical grade’ hearing aids

Apple unveiled its latest iPhone on Monday, along with updates to other key products like the Watch and the AirPods.

The new hardware bring some new looks, beefier under-the-hood processing power, and a slew of capabilities, including health features such as hearing aid and sleep apnea monitoring technology.

And of course, there’s Apple Intelligence, the company’s AI system, announced in June , coming to the latest iPhones, iPads, and Macs. You can watch a replay of the launch event video here .

And here’s a recap of all the new product announcements:

Four new models: iPhone 16, iPhone 16 Plus, iPhone 16 Pro, iPhone 16 Pro Max

The latest version of Apple’s flagship product, the iPhone, puts AI front and center , with a slew of integrated AI features, and two new buttons on the side of the device, including the a new “camera control” button.

The iPhone 16s have a new, touch sensitive “camera control” that lets users adjust settings like zoom and depth-of-field by sliding a finger alongside the surface of button, and quickly summon AI features by pressing the button when the phone is pointed at real world objects.

An “action” button, on the other side of the device, gives users a quick shortcut that can be customized to launch a variety of features. The button, which replaces the mute switch and was introduced in the iPhone 15 Pro models last year, will now be standard across all iPhone models.

While not as radical a shift in design as the foldable screen phones some of Apple’s competitors are rolling out , the new iPhone buttons are a big change in the context of Apple’s modus operandi.

The iPhone 16s will be powered by new A18 and A18 Pro chips, even smaller transistors that pack 17% more memory bandwidth. The A18 Pro tech boasts central processing that is 15% faster than on A17 Pro, and a graphics processing unit that is 20% faster.

Siri will learn to harness the power of Apple Intelligence. On the iPhone 16 Pro and Pro Max, Siri will use a “personal semantic index” to do things like rewrite notes into professional emails.

Writing tools integrated into iOS will turn notes into formal invites, tweak the tone of a Slack message, and create custom emojis (like a cowboy frog!). And by typing a description from your memory into photos, Apple Intelligence will retrieve footage, down to a specific moment in a video.

The Pro comes in four titanium finishes, including a new “desert” gold shade. Apple execs also boasted more powerful battery life for the suite of 16s but didn’t specify the capacity.

The iPhone 16 starts at $799 and $899 for the iPhone 16 Plus, with up to $800 off with trade in. The Pro model starts at $999.

Apple Watch Series X

Apple kicked off Monday’s event by unveiling the latest version of the Apple Watch — Series X (pronounced Series 10).

The Series X Watch, which starts at $399, will have the biggest display, thinnest design yet, with up to 30% more screen area than previous generations, Apple COO Jeff Williams said. And at 9.7 millimeters, the new watch is 10% thinner than Series 9, and weighs 20% less.

The Series X will be available in jet black, rose gold, and silver. Williams also announces Titanium finishes, which “celebrate the beauty of metal” in natural, gold, and slate gray.

As for AI: ML will help with crash detection, and a new neural network will make for clearer calls.

Along with ovulation and sleep stage tracking, the new watch will be able to detect sleep apnea using an accelerometer to identify breathing disturbances. Clearance from FDA and other regulators is expected soon, Apple said.

Apple executive Julz Arney said the Series X can detect water temperature and depth up to 20 ft – “perfect for snorkeling!” And a tides app will show rising, falling, high, and low tides with data for coastlines “all over the world.”

Series X starts at $399 and is available Sept. 20. Available for preorder starting today.

AirPods 4 and AirPods Pro

Apple’s showed off the fourth generation of its wireless AirPods, AirPods 4, and teased a new software update that will turn AirPods Pro 2 into a hearing aid.

Apple says it designed the new AirPods 4 by mapping and analyzing “thousands of earshapes” and generating 50 million data points — all of which will presumably make the earbuds fit snuggly.

Personalized Spatial Audio will enable an “immersive media experience,” and machine learning has made using AirPods for calls easier and clearer. AirPods will respond to a nod to pick up calls. There will be a button to play/pause music and mute or end calls. Apple is also offering a version of the AirPods 4 with active noise cancelling for an extra $50.

The case for the AirPods 4 is 10% smaller (hopefully not 10% easier to lose), and includes USB-C charging.

One of the most interesting bits of AirPods news is not about new hardware, but rather, a software update coming to the existing AirPods Pro. The update will transform the AirPods Pro into a “clinical grade” hearing aid for people with mild to moderate hearing loss, the company said, citing a study that found 75% of people diagnosed with hearing loss haven’t gotten help.

Apple will also release a 5-minute clinically validated hearing test that will be stored in the Health App as part of the hearing aid offering, which it said will be available in more than 100 countries this Fall following authorization from global health authorities.

Next Gen AirPods 4 are $129 and AirPods 4 with noise cancellation are $179. Available Sept. 20.

AirPods Max will now come in Midnight, blue, purple, orange and gold-ish “starlight.” They’re still $549.

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