examples of basic research questions

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How to Write a Research Question: Types and Examples 

The first step in any research project is framing the research question. It can be considered the core of any systematic investigation as the research outcomes are tied to asking the right questions. Thus, this primary interrogation point sets the pace for your research as it helps collect relevant and insightful information that ultimately influences your work.   

Typically, the research question guides the stages of inquiry, analysis, and reporting. Depending on the use of quantifiable or quantitative data, research questions are broadly categorized into quantitative or qualitative research questions. Both types of research questions can be used independently or together, considering the overall focus and objectives of your research.  

What is a research question?

A research question is a clear, focused, concise, and arguable question on which your research and writing are centered. 1 It states various aspects of the study, including the population and variables to be studied and the problem the study addresses. These questions also set the boundaries of the study, ensuring cohesion. 

Designing the research question is a dynamic process where the researcher can change or refine the research question as they review related literature and develop a framework for the study. Depending on the scale of your research, the study can include single or multiple research questions. 

A good research question has the following features: 

• It is relevant to the chosen field of study. 
• The question posed is arguable and open for debate, requiring synthesizing and analysis of ideas. 
• It is focused and concisely framed. 
• A feasible solution is possible within the given practical constraint and timeframe. 

A poorly formulated research question poses several risks. 1   

• Researchers can adopt an erroneous design. 
• It can create confusion and hinder the thought process, including developing a clear protocol.  
• It can jeopardize publication efforts.  
• It causes difficulty in determining the relevance of the study findings.  
• It causes difficulty in whether the study fulfils the inclusion criteria for systematic review and meta-analysis. This creates challenges in determining whether additional studies or data collection is needed to answer the question.  
• Readers may fail to understand the objective of the study. This reduces the likelihood of the study being cited by others. 

Now that you know “What is a research question?”, let’s look at the different types of research questions. 

Types of research questions

Depending on the type of research to be done, research questions can be classified broadly into quantitative, qualitative, or mixed-methods studies. Knowing the type of research helps determine the best type of research question that reflects the direction and epistemological underpinnings of your research. 

The structure and wording of quantitative 2 and qualitative research 3 questions differ significantly. The quantitative study looks at causal relationships, whereas the qualitative study aims at exploring a phenomenon. 

• Quantitative research questions:  
• Seeks to investigate social, familial, or educational experiences or processes in a particular context and/or location.  
• Answers ‘how,’ ‘what,’ or ‘why’ questions. 
• Investigates connections, relations, or comparisons between independent and dependent variables. 

Quantitative research questions can be further categorized into descriptive, comparative, and relationship, as explained in the Table below. 

• Qualitative research questions  

Qualitative research questions are adaptable, non-directional, and more flexible. It concerns broad areas of research or more specific areas of study to discover, explain, or explore a phenomenon. These are further classified as follows: 

• Mixed-methods studies  

Mixed-methods studies use both quantitative and qualitative research questions to answer your research question. Mixed methods provide a complete picture than standalone quantitative or qualitative research, as it integrates the benefits of both methods. Mixed methods research is often used in multidisciplinary settings and complex situational or societal research, especially in the behavioral, health, and social science fields. 

What makes a good research question

A good research question should be clear and focused to guide your research. It should synthesize multiple sources to present your unique argument, and should ideally be something that you are interested in. But avoid questions that can be answered in a few factual statements. The following are the main attributes of a good research question. 

• Specific: The research question should not be a fishing expedition performed in the hopes that some new information will be found that will benefit the researcher. The central research question should work with your research problem to keep your work focused. If using multiple questions, they should all tie back to the central aim. 
• Measurable: The research question must be answerable using quantitative and/or qualitative data or from scholarly sources to develop your research question. If such data is impossible to access, it is better to rethink your question. 
• Attainable: Ensure you have enough time and resources to do all research required to answer your question. If it seems you will not be able to gain access to the data you need, consider narrowing down your question to be more specific. 
• You have the expertise 
• You have the equipment and resources 
• Realistic: Developing your research question should be based on initial reading about your topic. It should focus on addressing a problem or gap in the existing knowledge in your field or discipline. 
• Based on some sort of rational physics 
• Can be done in a reasonable time frame 
• Timely: The research question should contribute to an existing and current debate in your field or in society at large. It should produce knowledge that future researchers or practitioners can later build on. 
• Novel 
• Based on current technologies. 
• Important to answer current problems or concerns. 
• Lead to new directions. 
• Important: Your question should have some aspect of originality. Incremental research is as important as exploring disruptive technologies. For example, you can focus on a specific location or explore a new angle. 
• Meaningful whether the answer is “Yes” or “No.” Closed-ended, yes/no questions are too simple to work as good research questions. Such questions do not provide enough scope for robust investigation and discussion. A good research question requires original data, synthesis of multiple sources, and original interpretation and argumentation before providing an answer. 

Steps for developing a good research question

The importance of research questions cannot be understated. When drafting a research question, use the following frameworks to guide the components of your question to ease the process. 4  

• Determine the requirements: Before constructing a good research question, set your research requirements. What is the purpose? Is it descriptive, comparative, or explorative research? Determining the research aim will help you choose the most appropriate topic and word your question appropriately. 
• Select a broad research topic: Identify a broader subject area of interest that requires investigation. Techniques such as brainstorming or concept mapping can help identify relevant connections and themes within a broad research topic. For example, how to learn and help students learn. 
• Perform preliminary investigation: Preliminary research is needed to obtain up-to-date and relevant knowledge on your topic. It also helps identify issues currently being discussed from which information gaps can be identified. 
• Narrow your focus: Narrow the scope and focus of your research to a specific niche. This involves focusing on gaps in existing knowledge or recent literature or extending or complementing the findings of existing literature. Another approach involves constructing strong research questions that challenge your views or knowledge of the area of study (Example: Is learning consistent with the existing learning theory and research). 
• Identify the research problem: Once the research question has been framed, one should evaluate it. This is to realize the importance of the research questions and if there is a need for more revising (Example: How do your beliefs on learning theory and research impact your instructional practices). 

How to write a research question

Those struggling to understand how to write a research question, these simple steps can help you simplify the process of writing a research question. 

Sample Research Questions

The following are some bad and good research question examples 

• Example 1 
• Example 2 

References:  

• Thabane, L., Thomas, T., Ye, C., & Paul, J. (2009). Posing the research question: not so simple.  Canadian Journal of Anesthesia/Journal canadien d’anesthésie ,  56 (1), 71-79. 
• Rutberg, S., & Bouikidis, C. D. (2018). Focusing on the fundamentals: A simplistic differentiation between qualitative and quantitative research.  Nephrology Nursing Journal ,  45 (2), 209-213. 
• Kyngäs, H. (2020). Qualitative research and content analysis.  The application of content analysis in nursing science research , 3-11. 
• Mattick, K., Johnston, J., & de la Croix, A. (2018). How to… write a good research question.  The clinical teacher ,  15 (2), 104-108. 
• Fandino, W. (2019). Formulating a good research question: Pearls and pitfalls.  Indian Journal of Anaesthesia ,  63 (8), 611. 
• Richardson, W. S., Wilson, M. C., Nishikawa, J., & Hayward, R. S. (1995). The well-built clinical question: a key to evidence-based decisions.  ACP journal club ,  123 (3), A12-A13 

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Home » Basic Research – Types, Methods and Examples

Basic Research – Types, Methods and Examples

Table of Contents

Basic Research

Definition:

Basic Research, also known as Fundamental or Pure Research , is scientific research that aims to increase knowledge and understanding about the natural world without necessarily having any practical or immediate applications. It is driven by curiosity and the desire to explore new frontiers of knowledge rather than by the need to solve a specific problem or to develop a new product.

Types of Basic Research

Types of Basic Research are as follows:

Experimental Research

This type of research involves manipulating one or more variables to observe their effect on a particular phenomenon. It aims to test hypotheses and establish cause-and-effect relationships.

Observational Research

This type of research involves observing and documenting natural phenomena without manipulating any variables. It aims to describe and understand the behavior of the observed system.

Theoretical Research

This type of research involves developing and testing theories and models to explain natural phenomena. It aims to provide a framework for understanding and predicting observations and experiments.

Descriptive Research

This type of research involves describing and cataloging natural phenomena without attempting to explain or understand them. It aims to provide a comprehensive and accurate picture of the observed system.

Comparative Research

This type of research involves comparing different systems or phenomena to identify similarities and differences. It aims to understand the underlying principles that govern different natural phenomena.

Historical Research

This type of research involves studying past events, developments, and discoveries to understand how science has evolved over time. It aims to provide insights into the factors that have influenced scientific progress and the role of basic research in shaping our understanding of the world.

Data Collection Methods

Some common data collection methods used in basic research include:

• Observation : This involves watching and recording natural phenomena in a systematic and structured way. Observations can be made in a laboratory setting or in the field and can be qualitative or quantitative.
• Surveys and questionnaires: These are tools for collecting data from a large number of individuals about their attitudes, beliefs, behaviors, and experiences. Surveys and questionnaires can be administered in person, by mail, or online.
• Interviews : Interviews involve asking questions to a person or a group of people to gather information about their experiences, opinions, and perspectives. Interviews can be structured, semi-structured, or unstructured.
• Experiments : Experiments involve manipulating one or more variables and observing their effect on a particular phenomenon. Experiments can be conducted in a laboratory or in the field and can be controlled or naturalistic.
• Case studies : Case studies involve in-depth analysis of a particular individual, group, or phenomenon. Case studies can provide rich and detailed information about complex phenomena.
• Archival research : Archival research involves analyzing existing data, documents, and records to answer research questions. Archival research can be used to study historical events, trends, and developments.
• Simulation : Simulation involves creating a computer model of a particular phenomenon to study its behavior and predict its future outcomes. Simulation can be used to study complex systems that are difficult to study in the real world.

Data Analysis Methods

Some common data analysis methods used in basic research include:

• Descriptive statistics: This involves summarizing and describing data using measures such as mean, median, mode, and standard deviation. Descriptive statistics provide a simple and easy way to understand the basic properties of the data.
• Inferential statistics : This involves making inferences about a population based on data collected from a sample. Inferential statistics can be used to test hypotheses, estimate parameters, and quantify uncertainty.
• Qualitative analysis : This involves analyzing data that are not numerical in nature, such as text, images, or audio recordings. Qualitative analysis can involve coding, categorizing, and interpreting data to identify themes, patterns, and relationships.
• Content analysis: This involves analyzing the content of text, images, or audio recordings to identify specific words, phrases, or themes. Content analysis can be used to study communication, media, and discourse.
• Multivariate analysis: This involves analyzing data that have multiple variables or factors. Multivariate analysis can be used to identify patterns and relationships among variables, cluster similar observations, and reduce the dimensionality of the data.
• Network analysis: This involves analyzing the structure and dynamics of networks, such as social networks, communication networks, or ecological networks. Network analysis can be used to study the relationships and interactions among individuals, groups, or entities.
• Machine learning : This involves using algorithms and models to analyze and make predictions based on data. Machine learning can be used to identify patterns, classify observations, and make predictions based on complex data sets.

Basic Research Methodology

Basic research methodology refers to the approach, techniques, and procedures used to conduct basic research. The following are some common steps involved in basic research methodology:

• Formulating research questions or hypotheses : This involves identifying the research problem and formulating specific questions or hypotheses that can guide the research.
• Reviewing the literature: This involves reviewing and synthesizing existing research on the topic of interest to identify gaps, controversies, and areas for further investigation.
• Designing the study: This involves designing a study that is appropriate for the research question or hypothesis. The study design can involve experiments, observations, surveys, case studies, or other methods.
• Collecting data: This involves collecting data using appropriate methods and instruments, such as observation, surveys, experiments, or interviews.
• Analyzing data: This involves analyzing the collected data using appropriate methods, such as descriptive or inferential statistics, qualitative analysis, or content analysis.
• Interpreting results : This involves interpreting the results of the data analysis in light of the research question or hypothesis and the existing literature.
• Drawing conclusions: This involves drawing conclusions based on the interpretation of the results and assessing their implications for the research question or hypothesis.
• Communicating findings : This involves communicating the research findings in the form of research reports, journal articles, conference presentations, or other forms of dissemination.

Applications of Basic Research

Some applications of basic research include:

• Medical breakthroughs : Basic research in fields such as biology, chemistry, and physics has led to important medical breakthroughs, including the discovery of antibiotics, vaccines, and new drugs.
• Technology advancements: Basic research in fields such as computer science, physics, and engineering has led to advancements in technology, such as the development of the internet, smartphones, and other electronic devices.
• Environmental solutions: Basic research in fields such as ecology, geology, and meteorology has led to the development of solutions to environmental problems, such as climate change, air pollution, and water contamination.
• Economic growth: Basic research can stimulate economic growth by creating new industries and markets based on scientific discoveries and technological advancements.
• National security: Basic research in fields such as physics, chemistry, and biology has led to the development of new technologies for national security, including encryption, radar, and stealth technology.

Examples of Basic Research

Here are some examples of basic research:

• Astronomy : Astronomers conduct basic research to understand the fundamental principles that govern the universe, such as the laws of gravity, the behavior of stars and galaxies, and the origins of the universe.
• Genetics : Geneticists conduct basic research to understand the genetic basis of various traits, diseases, and disorders. This research can lead to the development of new treatments and therapies for genetic diseases.
• Physics : Physicists conduct basic research to understand the fundamental principles of matter and energy, such as quantum mechanics, particle physics, and cosmology. This research can lead to new technologies and advancements in fields such as medicine and engineering.
• Neuroscience: Neuroscientists conduct basic research to understand the structure and function of the brain, including how it processes information and controls behavior. This research can lead to new treatments and therapies for neurological disorders and brain injuries.
• Mathematics : Mathematicians conduct basic research to develop and explore new mathematical theories, such as number theory, topology, and geometry. This research can lead to new applications in fields such as computer science, physics, and engineering.
• Chemistry : Chemists conduct basic research to understand the fundamental properties of matter and how it interacts with other substances. This research can lead to the development of new materials, drugs, and technologies.

Purpose of Basic Research

The purpose of basic research, also known as fundamental or pure research, is to expand knowledge in a particular field or discipline without any specific practical application in mind. The primary goal of basic research is to advance our understanding of the natural world and to uncover fundamental principles and relationships that underlie complex phenomena.

Basic research is often exploratory in nature, with researchers seeking to answer fundamental questions about how the world works. The research may involve conducting experiments, collecting and analyzing data, or developing new theories and hypotheses. Basic research often requires a high degree of creativity, innovation, and intellectual curiosity, as well as a willingness to take risks and pursue unconventional lines of inquiry.

Although basic research is not conducted with a specific practical outcome in mind, it can lead to significant practical applications in various fields. Many of the major scientific discoveries and technological advancements of the past century have been rooted in basic research, from the discovery of antibiotics to the development of the internet.

In summary, the purpose of basic research is to expand knowledge and understanding in a particular field or discipline, with the goal of uncovering fundamental principles and relationships that can help us better understand the natural world. While the practical applications of basic research may not always be immediately apparent, it has led to significant scientific and technological advancements that have benefited society in numerous ways.

When to use Basic Research

Basic research is generally conducted when scientists and researchers are seeking to expand knowledge and understanding in a particular field or discipline. It is particularly useful when there are gaps in our understanding of fundamental principles and relationships that underlie complex phenomena. Here are some situations where basic research might be particularly useful:

• Exploring new fields: Basic research can be particularly valuable when researchers are exploring new fields or areas of inquiry where little is known. By conducting basic research, scientists can establish a foundation of knowledge that can be built upon in future studies.
• Testing new theories: Basic research can be useful when researchers are testing new theories or hypotheses that have not been tested before. This can help scientists to gain a better understanding of how the world works and to identify areas where further research is needed.
• Developing new technologies : Basic research can be important for developing new technologies and innovations. By conducting basic research, scientists can uncover new materials, properties, and relationships that can be used to develop new products or technologies.
• Investigating complex phenomena : Basic research can be particularly valuable when investigating complex phenomena that are not yet well understood. By conducting basic research, scientists can gain a better understanding of the underlying principles and relationships that govern complex systems.
• Advancing scientific knowledge: Basic research is important for advancing scientific knowledge in general. By conducting basic research, scientists can uncover new principles and relationships that can be applied across multiple fields of study.

Characteristics of Basic Research

Here are some of the main characteristics of basic research:

• Focus on fundamental knowledge : Basic research is focused on expanding our understanding of the natural world and uncovering fundamental principles and relationships that underlie complex phenomena. The primary goal of basic research is to advance knowledge without any specific practical application in mind.
• Exploratory in nature: Basic research is often exploratory in nature, with researchers seeking to answer fundamental questions about how the world works. The research may involve conducting experiments, collecting and analyzing data, or developing new theories and hypotheses.
• Long-term focus: Basic research is often focused on long-term outcomes rather than immediate practical applications. The insights and discoveries generated by basic research may take years or even decades to translate into practical applications.
• High degree of creativity and innovation : Basic research often requires a high degree of creativity, innovation, and intellectual curiosity. Researchers must be willing to take risks and pursue unconventional lines of inquiry.
• Emphasis on scientific rigor: Basic research is conducted using the scientific method, which emphasizes the importance of rigorous experimental design, data collection and analysis, and peer review.
• Interdisciplinary: Basic research is often interdisciplinary, drawing on multiple fields of study to address complex research questions. Basic research can be conducted in fields ranging from physics and chemistry to biology and psychology.
• Open-ended : Basic research is open-ended, meaning that it does not have a specific end goal in mind. Researchers may follow unexpected paths or uncover new lines of inquiry that they had not anticipated.

Advantages of Basic Research

Here are some of the main advantages of basic research:

• Advancing scientific knowledge: Basic research is essential for expanding our understanding of the natural world and uncovering fundamental principles and relationships that underlie complex phenomena. This knowledge can be applied across multiple fields of study and can lead to significant scientific and technological advancements.
• Fostering innovation: Basic research often requires a high degree of creativity, innovation, and intellectual curiosity. By encouraging scientists to pursue unconventional lines of inquiry and take risks, basic research can lead to breakthrough discoveries and innovations.
• Stimulating economic growth : Basic research can lead to the development of new technologies and products that can stimulate economic growth and create new industries. Many of the major scientific and technological advancements of the past century have been rooted in basic research.
• Improving health and well-being: Basic research can lead to the development of new drugs, therapies, and medical treatments that can improve health and well-being. For example, many of the major advances in medical science, such as the development of antibiotics and vaccines, were rooted in basic research.
• Training the next generation of scientists : Basic research is essential for training the next generation of scientists and researchers. By providing opportunities for young scientists to engage in research and gain hands-on experience, basic research helps to develop the skills and expertise needed to advance scientific knowledge in the future.
• Encouraging interdisciplinary collaboration : Basic research often requires collaboration between scientists from different fields of study. By fostering interdisciplinary collaboration, basic research can lead to new insights and discoveries that would not be possible through single-discipline research alone.

Limitations of Basic Research

Here are some of the main limitations of basic research:

• Lack of immediate practical applications : Basic research is often focused on long-term outcomes rather than immediate practical applications. The insights and discoveries generated by basic research may take years or even decades to translate into practical applications.
• High cost and time requirements: Basic research can be expensive and time-consuming, as it often requires sophisticated equipment, specialized facilities, and large research teams. Funding for basic research can be limited, making it difficult to sustain long-term projects.
• Ethical concerns : Basic research may involve working with animal models or human subjects, raising ethical concerns around the use of animals or the safety and well-being of human participants.
• Uncertainty around outcomes: Basic research is often open-ended, meaning that it does not have a specific end goal in mind. This uncertainty can make it difficult to justify funding for basic research, as it is difficult to predict what outcomes the research will produce.
• Difficulty in communicating results : Basic research can produce complex and technical findings that may be difficult to communicate to the general public or policymakers. This can make it challenging to generate public support for basic research or to translate basic research findings into policy or practical applications.

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Basic Research in Psychology

Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

Emily is a board-certified science editor who has worked with top digital publishing brands like Voices for Biodiversity, Study.com, GoodTherapy, Vox, and Verywell.

Basic research—also known as fundamental or pure research—refers to study and research meant to increase our scientific knowledge base. This type of research is often purely theoretical, with the intent of increasing our understanding of certain phenomena or behavior. In contrast with applied research, basic research doesn't seek to solve or treat these problems.

Basic Research Examples

Basic research in psychology might explore:

• Whether stress levels influence how often students engage in academic cheating
• How caffeine consumption affects the brain
• Whether men or women are more likely to be diagnosed with depression
• How attachment styles among children of divorced parents compare to those raised by married parents

In all of these examples, the goal is merely to increase knowledge on a topic, not to come up with a practical solution to a problem.

The Link Between Basic and Applied Research

As Stanovich (2007) noted, many practical solutions to real-world problems have emerged directly from basic research. For this reason, the distinction between basic research and applied research is often simply a matter of time. As social psychologist Kurt Lewin once observed, "There is nothing so practical as a good theory."

For example, researchers might conduct basic research on how stress levels impact students academically, emotionally, and socially. The results of these theoretical explorations might lead to further studies designed to solve specific problems. Researchers might initially observe that students with high stress levels are more prone to dropping out of college before graduating. These first studies are examples of basic research designed to learn more about the topic.

As a result, scientists might then design research to determine what interventions might best lower these stress levels. Such studies would be examples of applied research. The purpose of applied research is specifically focused on solving a real problem that exists in the world. Thanks to the foundations established by basic research, psychologists can then design interventions that will help students effectively manage their stress levels , with the hopes of improving college retention rates.

Why Basic Research Is Important

The possible applications of basic research might not be obvious right away. During the earliest phases of basic research, scientists might not even be able to see how the information gleaned from theoretical research might ever apply to real-world problems. However, this foundational knowledge is essential. By learning as much as possible about a topic, researchers are able to gather what they need to know about an issue to fully understand the impact it may have.

"For example, early neuroscientists conducted basic research studies to understand how neurons function. The applications of this knowledge were not clear until much later when neuroscientists better understood how this neural functioning affected behavior," explained author Dawn M. McBride in her text The Process of Research in Psychology . "The understanding of the basic knowledge of neural functioning became useful in helping individuals with disorders long after this research had been completed."

Basic Research Methods

Basic research relies on many types of investigatory tools. These include observation, case studies, experiments, focus groups, surveys, interviews—anything that increases the scope of knowledge on the topic at hand.

Frequently Asked Questions

Psychologists interested in social behavior often undertake basic research. Social/community psychologists engaging in basic research are not trying to solve particular problems; rather, they want to learn more about why humans act the way they do.

Basic research is an effort to expand the scope of knowledge on a topic. Applied research uses such knowledge to solve specific problems.

An effective basic research problem statement outlines the importance of the topic; the study's significance and methods; what the research is investigating; how the results will be reported; and what the research will probably require.

Basic research might investigate, for example, the relationship between academic stress levels and cheating; how caffeine affects the brain; depression incidence in men vs. women; or attachment styles among children of divorced and married parents.

By learning as much as possible about a topic, researchers can come to fully understand the impact it may have. This knowledge can then become the basis of applied research to solve a particular problem within the topic area.

Stanovich KE.  How to Think Straight About Psychology . 8th edition. Boston, MA: Pearson Allyn and Bacon; 2007.

McCain KW. “Nothing as practical as a good theory” Does Lewin's Maxim still have salience in the applied social sciences? Proceedings of the Association for Information Science and Technology . 2015;52(1):1-4. doi:10.1002/pra2.2015.145052010077

McBride DM. The Process of Research in Psychology . 3rd edition . Thousand Oaks, CA: Sage Publications; 2015.

Committee on Department of Defense Basic Research. APPENDIX D: Definitions of basic, applied, and fundamental research . In: Assessment of Department of Defense Basic Research. Washington, D.C.: The National Academic Press; 2005.

By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

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How to Write a Good Research Question (w/ Examples)

What is a Research Question?

A research question is the main question that your study sought or is seeking to answer. A clear research question guides your research paper or thesis and states exactly what you want to find out, giving your work a focus and objective. Learning  how to write a hypothesis or research question is the start to composing any thesis, dissertation, or research paper. It is also one of the most important sections of a research proposal . 

A good research question not only clarifies the writing in your study; it provides your readers with a clear focus and facilitates their understanding of your research topic, as well as outlining your study’s objectives. Before drafting the paper and receiving research paper editing (and usually before performing your study), you should write a concise statement of what this study intends to accomplish or reveal.

Research Question Writing Tips

Listed below are the important characteristics of a good research question:

A good research question should:

• Be clear and provide specific information so readers can easily understand the purpose.
• Be focused in its scope and narrow enough to be addressed in the space allowed by your paper
• Be relevant and concise and express your main ideas in as few words as possible, like a hypothesis.
• Be precise and complex enough that it does not simply answer a closed “yes or no” question, but requires an analysis of arguments and literature prior to its being considered acceptable. 
• Be arguable or testable so that answers to the research question are open to scrutiny and specific questions and counterarguments.

Some of these characteristics might be difficult to understand in the form of a list. Let’s go into more detail about what a research question must do and look at some examples of research questions.

The research question should be specific and focused 

Research questions that are too broad are not suitable to be addressed in a single study. One reason for this can be if there are many factors or variables to consider. In addition, a sample data set that is too large or an experimental timeline that is too long may suggest that the research question is not focused enough.

A specific research question means that the collective data and observations come together to either confirm or deny the chosen hypothesis in a clear manner. If a research question is too vague, then the data might end up creating an alternate research problem or hypothesis that you haven’t addressed in your Introduction section .

The research question should be based on the literature 

An effective research question should be answerable and verifiable based on prior research because an effective scientific study must be placed in the context of a wider academic consensus. This means that conspiracy or fringe theories are not good research paper topics.

Instead, a good research question must extend, examine, and verify the context of your research field. It should fit naturally within the literature and be searchable by other research authors.

References to the literature can be in different citation styles and must be properly formatted according to the guidelines set forth by the publishing journal, university, or academic institution. This includes in-text citations as well as the Reference section . 

The research question should be realistic in time, scope, and budget

There are two main constraints to the research process: timeframe and budget.

A proper research question will include study or experimental procedures that can be executed within a feasible time frame, typically by a graduate doctoral or master’s student or lab technician. Research that requires future technology, expensive resources, or follow-up procedures is problematic.

A researcher’s budget is also a major constraint to performing timely research. Research at many large universities or institutions is publicly funded and is thus accountable to funding restrictions. 

The research question should be in-depth

Research papers, dissertations and theses , and academic journal articles are usually dozens if not hundreds of pages in length.

A good research question or thesis statement must be sufficiently complex to warrant such a length, as it must stand up to the scrutiny of peer review and be reproducible by other scientists and researchers.

Research Question Types

Qualitative and quantitative research are the two major types of research, and it is essential to develop research questions for each type of study. 

Quantitative Research Questions

Quantitative research questions are specific. A typical research question involves the population to be studied, dependent and independent variables, and the research design.

In addition, quantitative research questions connect the research question and the research design. In addition, it is not possible to answer these questions definitively with a “yes” or “no” response. For example, scientific fields such as biology, physics, and chemistry often deal with “states,” in which different quantities, amounts, or velocities drastically alter the relevance of the research.

As a consequence, quantitative research questions do not contain qualitative, categorical, or ordinal qualifiers such as “is,” “are,” “does,” or “does not.”

Categories of quantitative research questions

Qualitative research questions.

In quantitative research, research questions have the potential to relate to broad research areas as well as more specific areas of study. Qualitative research questions are less directional, more flexible, and adaptable compared with their quantitative counterparts. Thus, studies based on these questions tend to focus on “discovering,” “explaining,” “elucidating,” and “exploring.”

Categories of qualitative research questions

Quantitative and qualitative research question examples.

Good and Bad Research Question Examples

Below are some good (and not-so-good) examples of research questions that researchers can use to guide them in crafting their own research questions.

Research Question Example 1

The first research question is too vague in both its independent and dependent variables. There is no specific information on what “exposure” means. Does this refer to comments, likes, engagement, or just how much time is spent on the social media platform?

Second, there is no useful information on what exactly “affected” means. Does the subject’s behavior change in some measurable way? Or does this term refer to another factor such as the user’s emotions?

Research Question Example 2

In this research question, the first example is too simple and not sufficiently complex, making it difficult to assess whether the study answered the question. The author could really only answer this question with a simple “yes” or “no.” Further, the presence of data would not help answer this question more deeply, which is a sure sign of a poorly constructed research topic.

The second research question is specific, complex, and empirically verifiable. One can measure program effectiveness based on metrics such as attendance or grades. Further, “bullying” is made into an empirical, quantitative measurement in the form of recorded disciplinary actions.

Steps for Writing a Research Question

Good research questions are relevant, focused, and meaningful. It can be difficult to come up with a good research question, but there are a few steps you can follow to make it a bit easier.

1. Start with an interesting and relevant topic

Choose a research topic that is interesting but also relevant and aligned with your own country’s culture or your university’s capabilities. Popular academic topics include healthcare and medical-related research. However, if you are attending an engineering school or humanities program, you should obviously choose a research question that pertains to your specific study and major.

Below is an embedded graph of the most popular research fields of study based on publication output according to region. As you can see, healthcare and the basic sciences receive the most funding and earn the highest number of publications. 

2. Do preliminary research  

You can begin doing preliminary research once you have chosen a research topic. Two objectives should be accomplished during this first phase of research. First, you should undertake a preliminary review of related literature to discover issues that scholars and peers are currently discussing. With this method, you show that you are informed about the latest developments in the field.

Secondly, identify knowledge gaps or limitations in your topic by conducting a preliminary literature review . It is possible to later use these gaps to focus your research question after a certain amount of fine-tuning.

3. Narrow your research to determine specific research questions

You can focus on a more specific area of study once you have a good handle on the topic you want to explore. Focusing on recent literature or knowledge gaps is one good option. 

By identifying study limitations in the literature and overlooked areas of study, an author can carve out a good research question. The same is true for choosing research questions that extend or complement existing literature.

4. Evaluate your research question

Make sure you evaluate the research question by asking the following questions:

Is my research question clear?

The resulting data and observations that your study produces should be clear. For quantitative studies, data must be empirical and measurable. For qualitative, the observations should be clearly delineable across categories.

Is my research question focused and specific?

A strong research question should be specific enough that your methodology or testing procedure produces an objective result, not one left to subjective interpretation. Open-ended research questions or those relating to general topics can create ambiguous connections between the results and the aims of the study. 

Is my research question sufficiently complex?

The result of your research should be consequential and substantial (and fall sufficiently within the context of your field) to warrant an academic study. Simply reinforcing or supporting a scientific consensus is superfluous and will likely not be well received by most journal editors.  

Editing Your Research Question

Your research question should be fully formulated well before you begin drafting your research paper. However, you can receive English paper editing and proofreading services at any point in the drafting process. Language editors with expertise in your academic field can assist you with the content and language in your Introduction section or other manuscript sections. And if you need further assistance or information regarding paper compositions, in the meantime, check out our academic resources , which provide dozens of articles and videos on a variety of academic writing and publication topics.

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Basic Research: What it is with examples

In building knowledge, there are many stages and methodologies to generate insights that contribute to its understanding and advancement; basic research and applied research are usually the most effective on this path.

Understanding research allows us to understand all the properties of a specific science or phenomenon at a fundamental level. Some examples are branches such as sociology, humanities, and other scientific fields; below, we will tell you everything you need to know about this type of research and its possible applications.

What is Basic Research?

Basic Research is a type of research used in the scientific field to understand and extend our knowledge about a specific phenomenon or field. It is also accepted as pure investigation or fundamental research .

This type of research contributes to the intellectual body of knowledge. Basic research is concerned with the generalization of a theory in a branch of knowledge; its purpose is usually to generate data that confirm or refute the initial thesis of the study.

It can also be called foundational research; many things get built on this foundation, and more practical applications are made.

Basic Research vs. Applied Research

Basic Research finds its counterpart and complement in applied research. They are two handy research methods when generating and giving a utility to the generated data. There are very marked differences, and understanding them will allow you to understand the path followed to create new knowledge.

The most important difference between basic research and applied research lies in the objective of each. It seeks to expand the information and understanding of the object of study, while applied research aims to provide a solution to the problem studied.

The relationship between these two types of research is usually very close since the methodologies used are often quite similar; the significant change is found in the initial and final point of the investigation.

Basic Research Examples

There can be many examples of basic research; here are some of them:

• A study of how stress affects labor productivity.
• Studying the best factors of pricing strategies.
• Understand the client’s level of satisfaction before certain interactions with the company providing solutions.
• The understanding of the leadership style of a particular company.

Advantages & Disadvantages

Basic research is critical for expanding the pool of knowledge in any discipline. The introductory course usually does not have a strict period, and the researcher’s concern commonly guides them. The conclusion of the fundamental course is generally applicable in a wide range of cases and plots.

At the same time, the basic study has disadvantages as well. The findings of this type of study have limited or no constructive conclusions. In another sense, fundamental studies do not resolve complex and definite business problems, but it does help you understand them better.

Taking actions and decisions based on the results of this type of research will increase the impact these insights may have on the problem studied if that is the purpose.

LEARN ABOUT: Theoretical Research

How to do basic research?

This process follows the same steps as a standard research methodology. The most crucial point is to define a thesis or theory that involves a perfectly defined case study; this can be a phenomenon or a research problem observed in a particular place.

There are many types of research, such as longitudinal studies , observational research , and exploratory studies. So the first thing you should do is determine if you can obtain the desired result with research or if it is better to opt for another type of research.

Once you have determined your research methodology, the data collection process begins, also depending on your type of study; sometimes, you can collect the data passively through observation or experimentation. On other occasions, intervene directly and collect quantitative information with tools such as surveys.

Platforms like QuestionPro will help you have a wide range of functions and tools to carry out your research; its survey software has helped students and professionals obtain all the information necessary to generate high-value insights.

In addition, it has a data analysis suite with which you can analyze all this information using all kinds of reports for a more straightforward interpretation of the final results.

QuestionPro is much more than survey software ; we have a solution for each specific problem and industry. We also offer data management platforms such as our research data repository called Insights Hub.

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• Research Questions: Definitions, Types + [Examples]

Research questions lie at the core of systematic investigation and this is because recording accurate research outcomes is tied to asking the right questions. Asking the right questions when conducting research can help you collect relevant and insightful information that ultimately influences your work, positively. 

The right research questions are typically easy to understand, straight to the point, and engaging. In this article, we will share tips on how to create the right research questions and also show you how to create and administer an online questionnaire with Formplus . 

What is a Research Question? 

A research question is a specific inquiry which the research seeks to provide a response to. It resides at the core of systematic investigation and it helps you to clearly define a path for the research process. 

A research question is usually the first step in any research project. Basically, it is the primary interrogation point of your research and it sets the pace for your work.  

Typically, a research question focuses on the research, determines the methodology and hypothesis, and guides all stages of inquiry, analysis, and reporting. With the right research questions, you will be able to gather useful information for your investigation. 

Types of Research Questions 

Research questions are broadly categorized into 2; that is, qualitative research questions and quantitative research questions. Qualitative and quantitative research questions can be used independently and co-dependently in line with the overall focus and objectives of your research. 

If your research aims at collecting quantifiable data , you will need to make use of quantitative research questions. On the other hand, qualitative questions help you to gather qualitative data bothering on the perceptions and observations of your research subjects. 

Qualitative Research Questions  

A qualitative research question is a type of systematic inquiry that aims at collecting qualitative data from research subjects. The aim of qualitative research questions is to gather non-statistical information pertaining to the experiences, observations, and perceptions of the research subjects in line with the objectives of the investigation. 

Types of Qualitative Research Questions  

• Ethnographic Research Questions

As the name clearly suggests, ethnographic research questions are inquiries presented in ethnographic research. Ethnographic research is a qualitative research approach that involves observing variables in their natural environments or habitats in order to arrive at objective research outcomes. 

These research questions help the researcher to gather insights into the habits, dispositions, perceptions, and behaviors of research subjects as they interact in specific environments. 

Ethnographic research questions can be used in education, business, medicine, and other fields of study, and they are very useful in contexts aimed at collecting in-depth and specific information that are peculiar to research variables. For instance, asking educational ethnographic research questions can help you understand how pedagogy affects classroom relations and behaviors. 

This type of research question can be administered physically through one-on-one interviews, naturalism (live and work), and participant observation methods. Alternatively, the researcher can ask ethnographic research questions via online surveys and questionnaires created with Formplus.  

Examples of Ethnographic Research Questions

• Why do you use this product?
• Have you noticed any side effects since you started using this drug?
• Does this product meet your needs?

• Case Studies

A case study is a qualitative research approach that involves carrying out a detailed investigation into a research subject(s) or variable(s). In the course of a case study, the researcher gathers a range of data from multiple sources of information via different data collection methods, and over a period of time. 

The aim of a case study is to analyze specific issues within definite contexts and arrive at detailed research subject analyses by asking the right questions. This research method can be explanatory, descriptive , or exploratory depending on the focus of your systematic investigation or research. 

An explanatory case study is one that seeks to gather information on the causes of real-life occurrences. This type of case study uses “how” and “why” questions in order to gather valid information about the causative factors of an event. 

Descriptive case studies are typically used in business researches, and they aim at analyzing the impact of changing market dynamics on businesses. On the other hand, exploratory case studies aim at providing answers to “who” and “what” questions using data collection tools like interviews and questionnaires. 

Some questions you can include in your case studies are: 

• Why did you choose our services?
• How has this policy affected your business output?
• What benefits have you recorded since you started using our product?

An interview is a qualitative research method that involves asking respondents a series of questions in order to gather information about a research subject. Interview questions can be close-ended or open-ended , and they prompt participants to provide valid information that is useful to the research. 

An interview may also be structured, semi-structured , or unstructured , and this further influences the types of questions they include. Structured interviews are made up of more close-ended questions because they aim at gathering quantitative data while unstructured interviews consist, primarily, of open-ended questions that allow the researcher to collect qualitative information from respondents. 

You can conduct interview research by scheduling a physical meeting with respondents, through a telephone conversation, and via digital media and video conferencing platforms like Skype and Zoom. Alternatively, you can use Formplus surveys and questionnaires for your interview. 

Examples of interview questions include: 

• What challenges did you face while using our product?
• What specific needs did our product meet?
• What would you like us to improve our service delivery?

Quantitative Research Questions

Quantitative research questions are questions that are used to gather quantifiable data from research subjects. These types of research questions are usually more specific and direct because they aim at collecting information that can be measured; that is, statistical information. 

Types of Quantitative Research Questions

• Descriptive Research Questions

Descriptive research questions are inquiries that researchers use to gather quantifiable data about the attributes and characteristics of research subjects. These types of questions primarily seek responses that reveal existing patterns in the nature of the research subjects. 

It is important to note that descriptive research questions are not concerned with the causative factors of the discovered attributes and characteristics. Rather, they focus on the “what”; that is, describing the subject of the research without paying attention to the reasons for its occurrence. 

Descriptive research questions are typically closed-ended because they aim at gathering definite and specific responses from research participants. Also, they can be used in customer experience surveys and market research to collect information about target markets and consumer behaviors. 

Descriptive Research Question Examples

• How often do you make use of our fitness application?
• How much would you be willing to pay for this product?

• Comparative Research Questions

A comparative research question is a type of quantitative research question that is used to gather information about the differences between two or more research subjects across different variables. These types of questions help the researcher to identify distinct features that mark one research subject from the other while highlighting existing similarities. 

Asking comparative research questions in market research surveys can provide insights on how your product or service matches its competitors. In addition, it can help you to identify the strengths and weaknesses of your product for a better competitive advantage.  

The 5 steps involved in the framing of comparative research questions are: 

• Choose your starting phrase
• Identify and name the dependent variable
• Identify the groups you are interested in
• Identify the appropriate adjoining text
• Write out the comparative research question

Comparative Research Question Samples 

• What are the differences between a landline telephone and a smartphone?
• What are the differences between work-from-home and on-site operations?

• Relationship-based Research Questions  

Just like the name suggests, a relationship-based research question is one that inquires into the nature of the association between two research subjects within the same demographic. These types of research questions help you to gather information pertaining to the nature of the association between two research variables. 

Relationship-based research questions are also known as correlational research questions because they seek to clearly identify the link between 2 variables. 

Read: Correlational Research Designs: Types, Examples & Methods

Examples of relationship-based research questions include: 

• What is the relationship between purchasing power and the business site?
• What is the relationship between the work environment and workforce turnover?

Examples of a Good Research Question

Since research questions lie at the core of any systematic investigations, it is important to know how to frame a good research question. The right research questions will help you to gather the most objective responses that are useful to your systematic investigation. 

A good research question is one that requires impartial responses and can be answered via existing sources of information. Also, a good research question seeks answers that actively contribute to a body of knowledge; hence, it is a question that is yet to be answered in your specific research context.

• Open-Ended Questions

 An open-ended question is a type of research question that does not restrict respondents to a set of premeditated answer options. In other words, it is a question that allows the respondent to freely express his or her perceptions and feelings towards the research subject. 

Examples of Open-ended Questions

• How do you deal with stress in the workplace?
• What is a typical day at work like for you?
• Close-ended Questions

A close-ended question is a type of survey question that restricts respondents to a set of predetermined answers such as multiple-choice questions . Close-ended questions typically require yes or no answers and are commonly used in quantitative research to gather numerical data from research participants. 

Examples of Close-ended Questions

• Did you enjoy this event?
• How likely are you to recommend our services?
• Very Likely
• Somewhat Likely
• Likert Scale Questions

A Likert scale question is a type of close-ended question that is structured as a 3-point, 5-point, or 7-point psychometric scale . This type of question is used to measure the survey respondent’s disposition towards multiple variables and it can be unipolar or bipolar in nature. 

Example of Likert Scale Questions

• How satisfied are you with our service delivery?
• Very dissatisfied
• Not satisfied
• Very satisfied
• Rating Scale Questions

A rating scale question is a type of close-ended question that seeks to associate a specific qualitative measure (rating) with the different variables in research. It is commonly used in customer experience surveys, market research surveys, employee reviews, and product evaluations. 

Example of Rating Questions

• How would you rate our service delivery?

  Examples of a Bad Research Question

Knowing what bad research questions are would help you avoid them in the course of your systematic investigation. These types of questions are usually unfocused and often result in research biases that can negatively impact the outcomes of your systematic investigation. 

• Loaded Questions

A loaded question is a question that subtly presupposes one or more unverified assumptions about the research subject or participant. This type of question typically boxes the respondent in a corner because it suggests implicit and explicit biases that prevent objective responses. 

Example of Loaded Questions

• Have you stopped smoking?
• Where did you hide the money?
• Negative Questions

A negative question is a type of question that is structured with an implicit or explicit negator. Negative questions can be misleading because they upturn the typical yes/no response order by requiring a negative answer for affirmation and an affirmative answer for negation. 

Examples of Negative Questions

• Would you mind dropping by my office later today?
• Didn’t you visit last week?
• Leading Questions  

A l eading question is a type of survey question that nudges the respondent towards an already-determined answer. It is highly suggestive in nature and typically consists of biases and unverified assumptions that point toward its premeditated responses. 

Examples of Leading Questions

• If you enjoyed this service, would you be willing to try out our other packages?
• Our product met your needs, didn’t it?

Read More: Leading Questions: Definition, Types, and Examples

How to Use Formplus as Online Research Questionnaire Tool  

With Formplus, you can create and administer your online research questionnaire easily. In the form builder, you can add different form fields to your questionnaire and edit these fields to reflect specific research questions for your systematic investigation. 

Here is a step-by-step guide on how to create an online research questionnaire with Formplus: 

• Sign in to your Formplus accoun t, then click on the “create new form” button in your dashboard to access the Form builder.

• In the form builder, add preferred form fields to your online research questionnaire by dragging and dropping them into the form. Add a title to your form in the title block. You can edit form fields by clicking on the “pencil” icon on the right corner of each form field.

• Save the form to access the customization section of the builder. Here, you can tweak the appearance of your online research questionnaire by adding background images, changing the form font, and adding your organization’s logo.

• Finally, copy your form link and share it with respondents. You can also use any of the multiple sharing options available.

Conclusion  

The success of your research starts with framing the right questions to help you collect the most valid and objective responses. Be sure to avoid bad research questions like loaded and negative questions that can be misleading and adversely affect your research data and outcomes. 

Your research questions should clearly reflect the aims and objectives of your systematic investigation while laying emphasis on specific contexts. To help you seamlessly gather responses for your research questions, you can create an online research questionnaire on Formplus.  

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Research Aims, Objectives & Questions

The “Golden Thread” Explained Simply (+ Examples)

By: David Phair (PhD) and Alexandra Shaeffer (PhD) | June 2022

The research aims , objectives and research questions (collectively called the “golden thread”) are arguably the most important thing you need to get right when you’re crafting a research proposal , dissertation or thesis . We receive questions almost every day about this “holy trinity” of research and there’s certainly a lot of confusion out there, so we’ve crafted this post to help you navigate your way through the fog.

Overview: The Golden Thread

• What is the golden thread
• What are research aims ( examples )
• What are research objectives ( examples )
• What are research questions ( examples )
• The importance of alignment in the golden thread

What is the “golden thread”?  

The golden thread simply refers to the collective research aims , research objectives , and research questions for any given project (i.e., a dissertation, thesis, or research paper ). These three elements are bundled together because it’s extremely important that they align with each other, and that the entire research project aligns with them.

Importantly, the golden thread needs to weave its way through the entirety of any research project , from start to end. In other words, it needs to be very clearly defined right at the beginning of the project (the topic ideation and proposal stage) and it needs to inform almost every decision throughout the rest of the project. For example, your research design and methodology will be heavily influenced by the golden thread (we’ll explain this in more detail later), as well as your literature review.

The research aims, objectives and research questions (the golden thread) define the focus and scope ( the delimitations ) of your research project. In other words, they help ringfence your dissertation or thesis to a relatively narrow domain, so that you can “go deep” and really dig into a specific problem or opportunity. They also help keep you on track , as they act as a litmus test for relevance. In other words, if you’re ever unsure whether to include something in your document, simply ask yourself the question, “does this contribute toward my research aims, objectives or questions?”. If it doesn’t, chances are you can drop it.

Alright, enough of the fluffy, conceptual stuff. Let’s get down to business and look at what exactly the research aims, objectives and questions are and outline a few examples to bring these concepts to life.

Research Aims: What are they?

Simply put, the research aim(s) is a statement that reflects the broad overarching goal (s) of the research project. Research aims are fairly high-level (low resolution) as they outline the general direction of the research and what it’s trying to achieve .

Research Aims: Examples  

True to the name, research aims usually start with the wording “this research aims to…”, “this research seeks to…”, and so on. For example:

“This research aims to explore employee experiences of digital transformation in retail HR.”   “This study sets out to assess the interaction between student support and self-care on well-being in engineering graduate students”  

As you can see, these research aims provide a high-level description of what the study is about and what it seeks to achieve. They’re not hyper-specific or action-oriented, but they’re clear about what the study’s focus is and what is being investigated.

Need a helping hand?

Research Objectives: What are they?

The research objectives take the research aims and make them more practical and actionable . In other words, the research objectives showcase the steps that the researcher will take to achieve the research aims.

The research objectives need to be far more specific (higher resolution) and actionable than the research aims. In fact, it’s always a good idea to craft your research objectives using the “SMART” criteria. In other words, they should be specific, measurable, achievable, relevant and time-bound”.

Research Objectives: Examples  

Let’s look at two examples of research objectives. We’ll stick with the topic and research aims we mentioned previously.  

For the digital transformation topic:

To observe the retail HR employees throughout the digital transformation. To assess employee perceptions of digital transformation in retail HR. To identify the barriers and facilitators of digital transformation in retail HR.

And for the student wellness topic:

To determine whether student self-care predicts the well-being score of engineering graduate students. To determine whether student support predicts the well-being score of engineering students. To assess the interaction between student self-care and student support when predicting well-being in engineering graduate students.

  As you can see, these research objectives clearly align with the previously mentioned research aims and effectively translate the low-resolution aims into (comparatively) higher-resolution objectives and action points . They give the research project a clear focus and present something that resembles a research-based “to-do” list.

Research Questions: What are they?

Finally, we arrive at the all-important research questions. The research questions are, as the name suggests, the key questions that your study will seek to answer . Simply put, they are the core purpose of your dissertation, thesis, or research project. You’ll present them at the beginning of your document (either in the introduction chapter or literature review chapter) and you’ll answer them at the end of your document (typically in the discussion and conclusion chapters).  

The research questions will be the driving force throughout the research process. For example, in the literature review chapter, you’ll assess the relevance of any given resource based on whether it helps you move towards answering your research questions. Similarly, your methodology and research design will be heavily influenced by the nature of your research questions. For instance, research questions that are exploratory in nature will usually make use of a qualitative approach, whereas questions that relate to measurement or relationship testing will make use of a quantitative approach.  

Let’s look at some examples of research questions to make this more tangible.

Research Questions: Examples  

Again, we’ll stick with the research aims and research objectives we mentioned previously.  

For the digital transformation topic (which would be qualitative in nature):

How do employees perceive digital transformation in retail HR? What are the barriers and facilitators of digital transformation in retail HR?  

And for the student wellness topic (which would be quantitative in nature):

Does student self-care predict the well-being scores of engineering graduate students? Does student support predict the well-being scores of engineering students? Do student self-care and student support interact when predicting well-being in engineering graduate students?  

You’ll probably notice that there’s quite a formulaic approach to this. In other words, the research questions are basically the research objectives “converted” into question format. While that is true most of the time, it’s not always the case. For example, the first research objective for the digital transformation topic was more or less a step on the path toward the other objectives, and as such, it didn’t warrant its own research question.  

So, don’t rush your research questions and sloppily reword your objectives as questions. Carefully think about what exactly you’re trying to achieve (i.e. your research aim) and the objectives you’ve set out, then craft a set of well-aligned research questions . Also, keep in mind that this can be a somewhat iterative process , where you go back and tweak research objectives and aims to ensure tight alignment throughout the golden thread.

The importance of strong alignment 

Alignment is the keyword here and we have to stress its importance . Simply put, you need to make sure that there is a very tight alignment between all three pieces of the golden thread. If your research aims and research questions don’t align, for example, your project will be pulling in different directions and will lack focus . This is a common problem students face and can cause many headaches (and tears), so be warned.

Take the time to carefully craft your research aims, objectives and research questions before you run off down the research path. Ideally, get your research supervisor/advisor to review and comment on your golden thread before you invest significant time into your project, and certainly before you start collecting data .  

Recap: The golden thread

In this post, we unpacked the golden thread of research, consisting of the research aims , research objectives and research questions . You can jump back to any section using the links below.

As always, feel free to leave a comment below – we always love to hear from you. Also, if you’re interested in 1-on-1 support, take a look at our private coaching service here.

Psst... there’s more!

This post was based on one of our popular Research Bootcamps . If you're working on a research project, you'll definitely want to check this out ...

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39 Comments

Thank you very much for your great effort put. As an Undergraduate taking Demographic Research & Methodology, I’ve been trying so hard to understand clearly what is a Research Question, Research Aim and the Objectives in a research and the relationship between them etc. But as for now I’m thankful that you’ve solved my problem.

Well appreciated. This has helped me greatly in doing my dissertation.

An so delighted with this wonderful information thank you a lot.

so impressive i have benefited a lot looking forward to learn more on research.

I am very happy to have carefully gone through this well researched article.

Infact,I used to be phobia about anything research, because of my poor understanding of the concepts.

Now,I get to know that my research question is the same as my research objective(s) rephrased in question format.

I please I would need a follow up on the subject,as I intends to join the team of researchers. Thanks once again.

Thanks so much. This was really helpful.

I know you pepole have tried to break things into more understandable and easy format. And God bless you. Keep it up

i found this document so useful towards my study in research methods. thanks so much.

This is my 2nd read topic in your course and I should commend the simplified explanations of each part. I’m beginning to understand and absorb the use of each part of a dissertation/thesis. I’ll keep on reading your free course and might be able to avail the training course! Kudos!

Thank you! Better put that my lecture and helped to easily understand the basics which I feel often get brushed over when beginning dissertation work.

This is quite helpful. I like how the Golden thread has been explained and the needed alignment.

This is quite helpful. I really appreciate!

The article made it simple for researcher students to differentiate between three concepts.

Very innovative and educational in approach to conducting research.

I am very impressed with all these terminology, as I am a fresh student for post graduate, I am highly guided and I promised to continue making consultation when the need arise. Thanks a lot.

A very helpful piece. thanks, I really appreciate it .

Very well explained, and it might be helpful to many people like me.

Wish i had found this (and other) resource(s) at the beginning of my PhD journey… not in my writing up year… 😩 Anyways… just a quick question as i’m having some issues ordering my “golden thread”…. does it matter in what order you mention them? i.e., is it always first aims, then objectives, and finally the questions? or can you first mention the research questions and then the aims and objectives?

Thank you for a very simple explanation that builds upon the concepts in a very logical manner. Just prior to this, I read the research hypothesis article, which was equally very good. This met my primary objective.

My secondary objective was to understand the difference between research questions and research hypothesis, and in which context to use which one. However, I am still not clear on this. Can you kindly please guide?

In research, a research question is a clear and specific inquiry that the researcher wants to answer, while a research hypothesis is a tentative statement or prediction about the relationship between variables or the expected outcome of the study. Research questions are broader and guide the overall study, while hypotheses are specific and testable statements used in quantitative research. Research questions identify the problem, while hypotheses provide a focus for testing in the study.

Exactly what I need in this research journey, I look forward to more of your coaching videos.

This helped a lot. Thanks so much for the effort put into explaining it.

What data source in writing dissertation/Thesis requires?

What is data source covers when writing dessertation/thesis

This is quite useful thanks

I’m excited and thankful. I got so much value which will help me progress in my thesis.

where are the locations of the reserch statement, research objective and research question in a reserach paper? Can you write an ouline that defines their places in the researh paper?

Very helpful and important tips on Aims, Objectives and Questions.

Thank you so much for making research aim, research objectives and research question so clear. This will be helpful to me as i continue with my thesis.

Thanks much for this content. I learned a lot. And I am inspired to learn more. I am still struggling with my preparation for dissertation outline/proposal. But I consistently follow contents and tutorials and the new FB of GRAD Coach. Hope to really become confident in writing my dissertation and successfully defend it.

As a researcher and lecturer, I find splitting research goals into research aims, objectives, and questions is unnecessarily bureaucratic and confusing for students. For most biomedical research projects, including ‘real research’, 1-3 research questions will suffice (numbers may differ by discipline).

Awesome! Very important resources and presented in an informative way to easily understand the golden thread. Indeed, thank you so much.

Well explained

The blog article on research aims, objectives, and questions by Grad Coach is a clear and insightful guide that aligns with my experiences in academic research. The article effectively breaks down the often complex concepts of research aims and objectives, providing a straightforward and accessible explanation. Drawing from my own research endeavors, I appreciate the practical tips offered, such as the need for specificity and clarity when formulating research questions. The article serves as a valuable resource for students and researchers, offering a concise roadmap for crafting well-defined research goals and objectives. Whether you’re a novice or an experienced researcher, this article provides practical insights that contribute to the foundational aspects of a successful research endeavor.

A great thanks for you. it is really amazing explanation. I grasp a lot and one step up to research knowledge.

I really found these tips helpful. Thank you very much Grad Coach.

I found this article helpful. Thanks for sharing this.

thank you so much, the explanation and examples are really helpful

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25 Basic Research Examples

Basic research is research that focuses on expanding human knowledge, without obvious practical applications.

For a scholarly definition, we can turn to Grimsgaard (2023):

“Basic research, also called pure, theoretical or fundamental research, tends to focus more on ‘big picture’ topics, such as increasing the scientific knowledge base around a particular topic.”

It is contrasted with applied research , which “seeks to solve real world problems” (Lehmann, 2023).

Generally, basis research has no clear economic or market value, meaning it tends to take place in universities rather than private organizations. Nevertheless, this blue-skies basic research can lead to enormous technological breakthroughs that forms the foundation for future applied research .

Basic Research Examples

• Physics: Understanding the properties of neutrinos.
• Medicine: Investigating the role of gut microbiota in mental health.
• Anthropology: Studying the social structures of ancient civilizations.
• Biology: Exploring the mechanism of CRISPR-Cas9 gene editing.
• Psychology: Understanding the cognitive development in infants.
• Chemistry: Researching new catalytic processes for organic synthesis.
• Astronomy: Investigating the life cycle of stars.
• Sociology: Exploring the impacts of social media on society.
• Ecology: Studying the biodiversity in rainforests.
• Computer Science: Developing new algorithms for machine learning.
• Mathematics: Exploring new approaches to number theory.
• Economics: Investigating the causes and effects of inflation.
• Linguistics: Researching the evolution of languages over time.
• Political Science: Studying the effects of political campaigns on voter behavior.
• Geology: Investigating the formation of mountain ranges.
• Architecture: Studying ancient building techniques and materials.
• Education: Researching the impact of remote learning on academic performance.
• History: Investigating trade routes in the medieval period.
• Literature: Analyzing symbolism in 19th-century novels.
• Philosophy: Exploring concepts of justice in different cultures.
• Environmental Science: Studying the impact of plastics on marine life.
• Genetics: Investigating the role of specific genes in aging.
• Engineering: Researching materials for improving battery technology.
• Art History: Investigating the influence of politics on Renaissance art.
• Agricultural Science: Studying the impact of pest management practices on crop yield.

Case Studies

1. understanding the structure of the atom.

The study of atomic structure began in the early 1800s, with John Dalton’s atomic theory suggesting that atoms were indivisible and indestructible. However, it was not until the 20th century that Ernest Rutherford’s gold foil experiment led to the discovery of the nucleus and the proposal of the planetary model of the atom, which was further refined by Niels Bohr and eventually led to the quantum mechanical model, showing that electrons move in orbital shells around the nucleus.

Research Context:

• Topic: Investigating the structure and behavior of atoms.
• Purpose: Understand the fundamental particles (protons, neutrons, and electrons) and forces that govern atomic behavior.
• Methodology: Utilize particle accelerators, theoretical models, and experimental physics.
• Significance: Fundamental understanding of atomic structures has paved the way for numerous technological and scientific breakthroughs, such as the development of nuclear energy and advancements in chemistry and materials science.

Outcomes and Further Developments:

• Discovery and exploration of subatomic particles like quarks.
• Development of quantum mechanics and quantum field theory.
• Subsequent advancements in various scientific fields, such as nuclear physics, chemistry, and nanotechnology.

2. Researching the Human Genome

The Human Genome Project, an international research effort that began in 1990, aimed to sequence and map all of the genes – collectively known as the genome – of humans. Completed in 2003, it represented a monumental achievement in science, providing researchers with powerful tools to understand the genetic factors in human disease, paving the way for new strategies for diagnosis, treatment, and prevention.

• Topic: Investigating the structure, function, and mapping of the human genome.
• Purpose: Understand the genetic makeup of humans, identify genes, and learn how they work.
• Methodology: Techniques like DNA sequencing, genetic mapping, and computational biology.
• Significance: Foundational for various advancements in genetics, medicine, and biology, providing insights into diseases, development, and evolution.
• Completion of the Human Genome Project, which mapped the entire human genome.
• Advancements in personalized medicine, genetic testing, and gene therapy.
• Development of CRISPR technology, enabling precise genetic editing.

Basic Research vs Applied Research

Basic research focuses on expanding knowledge and understanding fundamental concepts without immediate practical application, while applied research focuses on solving specific, practical problems using the knowledge gained from basic research (Akcigit, Hanley & Serrano-Velarde, 2021).

A simple comparison of definitions is below:

• Basic research seeks to gain greater knowledge or understanding of the fundamental aspects of phenomena.
• Applied research seeks to solve practical problems the researcher or their stakeholders are facing.

A researcher might choose basic research over applied if their primary motivation is to expand the boundaries of human knowledge and contribute to academic theories, whilst they might favor applied research if they are more interested in achieving immediate solutions, innovations, or enhancements impacting real-world scenarios (Akcigit, Hanley & Serrano-Velarde, 2021; Baetu, 2016).

To learn more about applied research, check out my article on applied research.

Basic Research: Disappearing in 21st Century Universities?

In the 1980s, universities increasingly came under pressure to prove their specific financial value to society. This has only intensified over the decades. So, whereas once universities were preoccupied with basic research, there’s been a big push toward academic-industry collaborations where research demonstrates its economic value, rather than its cultural or intellectual value, to society. This may, on the one hand, help make universities relevant to today’s world. But on the other hand, it may interfere with the blue skies research that could identify and solve the bigger, less financially pressing, questions and problems of our ages (Bentley, Gulbrandsen & Kyvik, 2015).

Pros and Cons of Basic Research

The primary advantage of basic research is that it generates knowledge and understanding of fundamental principles that can later serve as a foundation for technological advancement or social betterment.

It can lead to groundbreaking discoveries, stimulate creativity, and drive scientific innovation by satisfying human curiosity (Akcigit, Hanley & Serrano-Velarde, 2021; Baetu, 2016).

It is also often the catalyst for training the next generation of scientists and researchers.

However, basic research can be time-consuming, expensive, and its outcomes may not always be directly observable or immediately beneficial.

This is why it’s often left to government-funded research institutes and universities to conduct this sort of research. As Binswanger (2014) argues, “basic research constitutes, for the most part, a common good which cannot be sold profitably on markets.

Furthermore, its value is often underestimated because the applications are not immediately apparent or tangible.

Below is a summary of some advantages and disadvantages of basic research:

Abeysekera, A. (2019). Basic research and applied research.  Journal of the National Science Foundation of Sri Lanka ,  47 (3).

Akcigit, U., Hanley, D., & Serrano-Velarde, N. (2021). Back to basics: Basic research spillovers, innovation policy, and growth.  The Review of Economic Studies ,  88 (1), 1-43.

Baetu, T. M. (2016). The ‘big picture’: the problem of extrapolation in basic research. The British Journal for the Philosophy of Science.

Bentley, P. J., Gulbrandsen, M., & Kyvik, S. (2015). The relationship between basic and applied research in universities.  Higher Education ,  70 , 689-709. ( Source )

Binswanger, M. (2014). How nonsense became excellence: forcing professors to publish. In Welpe, I. M., Wollersheim, J., Osterloh, M., & Ringelhan, S. (Eds.), Incentives and Performance: Governance of Research Organizations . Springer International Publishing.

Grimsgaard, W. (2023). Design and strategy: a step by step guide . New York: Taylor & Francis.

Lehmann, W. (2023). Social Media Theory and Communications Practice . London: Taylor & Francis.

Wiid, J., & Diggines, C. (2009). Marketing Research . Juta.

Chris Drew (PhD)

Dr. Chris Drew is the founder of the Helpful Professor. He holds a PhD in education and has published over 20 articles in scholarly journals. He is the former editor of the Journal of Learning Development in Higher Education. [Image Descriptor: Photo of Chris]

• Chris Drew (PhD) https://helpfulprofessor.com/author/chris-drew-phd/ 15 Animism Examples
• Chris Drew (PhD) https://helpfulprofessor.com/author/chris-drew-phd/ 10 Magical Thinking Examples
• Chris Drew (PhD) https://helpfulprofessor.com/author/chris-drew-phd/ Social-Emotional Learning (Definition, Examples, Pros & Cons)
• Chris Drew (PhD) https://helpfulprofessor.com/author/chris-drew-phd/ What is Educational Psychology?

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How to Develop a Good Research Question? — Types & Examples

Cecilia is living through a tough situation in her research life. Figuring out where to begin, how to start her research study, and how to pose the right question for her research quest, is driving her insane. Well, questions, if not asked correctly, have a tendency to spiral us!

Image Source: https://phdcomics.com/

Questions lead everyone to answers. Research is a quest to find answers. Not the vague questions that Cecilia means to answer, but definitely more focused questions that define your research. Therefore, asking appropriate question becomes an important matter of discussion.

A well begun research process requires a strong research question. It directs the research investigation and provides a clear goal to focus on. Understanding the characteristics of comprising a good research question will generate new ideas and help you discover new methods in research.

In this article, we are aiming to help researchers understand what is a research question and how to write one with examples.

Table of Contents

What Is a Research Question?

A good research question defines your study and helps you seek an answer to your research. Moreover, a clear research question guides the research paper or thesis to define exactly what you want to find out, giving your work its objective. Learning to write a research question is the beginning to any thesis, dissertation , or research paper. Furthermore, the question addresses issues or problems which is answered through analysis and interpretation of data.

Why Is a Research Question Important?

A strong research question guides the design of a study. Moreover, it helps determine the type of research and identify specific objectives. Research questions state the specific issue you are addressing and focus on outcomes of the research for individuals to learn. Therefore, it helps break up the study into easy steps to complete the objectives and answer the initial question.

Types of Research Questions

Research questions can be categorized into different types, depending on the type of research you want to undergo. Furthermore, knowing the type of research will help a researcher determine the best type of research question to use.

1. Qualitative Research Question

Qualitative questions concern broad areas or more specific areas of research. However, unlike quantitative questions, qualitative research questions are adaptable, non-directional and more flexible. Qualitative research question focus on discovering, explaining, elucidating, and exploring.

i. Exploratory Questions

This form of question looks to understand something without influencing the results. The objective of exploratory questions is to learn more about a topic without attributing bias or preconceived notions to it.

Research Question Example: Asking how a chemical is used or perceptions around a certain topic.

ii. Predictive Questions

Predictive research questions are defined as survey questions that automatically predict the best possible response options based on text of the question. Moreover, these questions seek to understand the intent or future outcome surrounding a topic.

Research Question Example: Asking why a consumer behaves in a certain way or chooses a certain option over other.

iii. Interpretive Questions

This type of research question allows the study of people in the natural setting. The questions help understand how a group makes sense of shared experiences with regards to various phenomena. These studies gather feedback on a group’s behavior without affecting the outcome.

Research Question Example: How do you feel about AI assisting publishing process in your research?

2. Quantitative Research Question

Quantitative questions prove or disprove a researcher’s hypothesis through descriptions, comparisons, and relationships. These questions are beneficial when choosing a research topic or when posing follow-up questions that garner more information.

i. Descriptive Questions

It is the most basic type of quantitative research question and it seeks to explain when, where, why, or how something occurred. Moreover, they use data and statistics to describe an event or phenomenon.

Research Question Example: How many generations of genes influence a future generation?

ii. Comparative Questions

Sometimes it’s beneficial to compare one occurrence with another. Therefore, comparative questions are helpful when studying groups with dependent variables.

Example: Do men and women have comparable metabolisms?

iii. Relationship-Based Questions

This type of research question answers influence of one variable on another. Therefore, experimental studies use this type of research questions are majorly.

Example: How is drought condition affect a region’s probability for wildfires.  

How to Write a Good Research Question?

1. Select a Topic

The first step towards writing a good research question is to choose a broad topic of research. You could choose a research topic that interests you, because the complete research will progress further from the research question. Therefore, make sure to choose a topic that you are passionate about, to make your research study more enjoyable.

2. Conduct Preliminary Research

After finalizing the topic, read and know about what research studies are conducted in the field so far. Furthermore, this will help you find articles that talk about the topics that are yet to be explored. You could explore the topics that the earlier research has not studied.

3. Consider Your Audience

The most important aspect of writing a good research question is to find out if there is audience interested to know the answer to the question you are proposing. Moreover, determining your audience will assist you in refining your research question, and focus on aspects that relate to defined groups.

4. Generate Potential Questions

The best way to generate potential questions is to ask open ended questions. Questioning broader topics will allow you to narrow down to specific questions. Identifying the gaps in literature could also give you topics to write the research question. Moreover, you could also challenge the existing assumptions or use personal experiences to redefine issues in research.

5. Review Your Questions

Once you have listed few of your questions, evaluate them to find out if they are effective research questions. Moreover while reviewing, go through the finer details of the question and its probable outcome, and find out if the question meets the research question criteria.

6. Construct Your Research Question

There are two frameworks to construct your research question. The first one being PICOT framework , which stands for:

• Population or problem
• Intervention or indicator being studied
• Comparison group
• Outcome of interest
• Time frame of the study.

The second framework is PEO , which stands for:

• Population being studied
• Exposure to preexisting conditions
• Outcome of interest.

Research Question Examples

• How might the discovery of a genetic basis for alcoholism impact triage processes in medical facilities?
• How do ecological systems respond to chronic anthropological disturbance?
• What are demographic consequences of ecological interactions?
• What roles do fungi play in wildfire recovery?
• How do feedbacks reinforce patterns of genetic divergence on the landscape?
• What educational strategies help encourage safe driving in young adults?
• What makes a grocery store easy for shoppers to navigate?
• What genetic factors predict if someone will develop hypothyroidism?
• Does contemporary evolution along the gradients of global change alter ecosystems function?

How did you write your first research question ? What were the steps you followed to create a strong research question? Do write to us or comment below.

Frequently Asked Questions

Research questions guide the focus and direction of a research study. Here are common types of research questions: 1. Qualitative research question: Qualitative questions concern broad areas or more specific areas of research. However, unlike quantitative questions, qualitative research questions are adaptable, non-directional and more flexible. Different types of qualitative research questions are: i. Exploratory questions ii. Predictive questions iii. Interpretive questions 2. Quantitative Research Question: Quantitative questions prove or disprove a researcher’s hypothesis through descriptions, comparisons, and relationships. These questions are beneficial when choosing a research topic or when posing follow-up questions that garner more information. Different types of quantitative research questions are: i. Descriptive questions ii. Comparative questions iii. Relationship-based questions

Qualitative research questions aim to explore the richness and depth of participants' experiences and perspectives. They should guide your research and allow for in-depth exploration of the phenomenon under investigation. After identifying the research topic and the purpose of your research: • Begin with Broad Inquiry: Start with a general research question that captures the main focus of your study. This question should be open-ended and allow for exploration. • Break Down the Main Question: Identify specific aspects or dimensions related to the main research question that you want to investigate. • Formulate Sub-questions: Create sub-questions that delve deeper into each specific aspect or dimension identified in the previous step. • Ensure Open-endedness: Make sure your research questions are open-ended and allow for varied responses and perspectives. Avoid questions that can be answered with a simple "yes" or "no." Encourage participants to share their experiences, opinions, and perceptions in their own words. • Refine and Review: Review your research questions to ensure they align with your research purpose, topic, and objectives. Seek feedback from your research advisor or peers to refine and improve your research questions.

Developing research questions requires careful consideration of the research topic, objectives, and the type of study you intend to conduct. Here are the steps to help you develop effective research questions: 1. Select a Topic 2. Conduct Preliminary Research 3. Consider Your Audience 4. Generate Potential Questions 5. Review Your Questions 6. Construct Your Research Question Based on PICOT or PEO Framework

There are two frameworks to construct your research question. The first one being PICOT framework, which stands for: • Population or problem • Intervention or indicator being studied • Comparison group • Outcome of interest • Time frame of the study The second framework is PEO, which stands for: • Population being studied • Exposure to preexisting conditions • Outcome of interest

A tad helpful

Had trouble coming up with a good research question for my MSc proposal. This is very much helpful.

This is a well elaborated writing on research questions development. I found it very helpful.

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415 Research Question Examples Across 15 Disciplines

A research question is a clearly formulated query that delineates the scope and direction of an investigation. It serves as the guiding light for scholars, helping them to dissect, analyze, and comprehend complex phenomena. Beyond merely seeking answers, a well-crafted research question ensures that the exploration remains focused and goal-oriented.

The significance of framing a clear, concise, and researchable question cannot be overstated. A well-defined question not only clarifies the objective of the research but also determines the methodologies and tools a researcher will employ. A concise question ensures precision, eliminating the potential for ambiguity or misinterpretation. Furthermore, the question must be researchable—posing a question that is too broad, too subjective, or unanswerable can lead to inconclusive results or an endless loop of investigation. In essence, the foundation of any meaningful academic endeavor rests on the articulation of a compelling and achievable research question.

Research questions can be categorized based on their intent and the nature of the information they seek. Recognizing the different types is essential for crafting an effective inquiry and guiding the research process. Let's delve into the various categories:

• Descriptive Research Questions: These types of questions aim to outline and characterize specific phenomena or attributes. They seek to provide a clear picture of a situation or context without necessarily diving into causal relationships. For instance, a question like "What are the main symptoms of the flu?" is descriptive as it seeks to list the symptoms.
• Explanatory (or Causal) Research Questions: Explanatory questions delve deeper, trying to uncover the reasons or causes behind certain phenomena. They are particularly common in experimental research where researchers are attempting to establish cause-and-effect relationships. An example might be, "Does smoking increase the risk of lung cancer?"
• Exploratory Research Questions: As the name suggests, these questions are used when researchers are entering uncharted territories. They are designed to gather preliminary information on topics that haven't been studied extensively. A question like "How do emerging technologies impact remote tribal communities?" can be seen as exploratory if there's limited existing research on the topic.
• Comparative Research Questions: These questions are formulated when the objective is to compare two or more groups, conditions, or variables. Comparative questions might look like "How do test scores differ between students who study regularly and those who cram?"
• Predictive Research Questions: The goal here is to forecast or predict potential outcomes based on certain variables or conditions. Predictive research might pose questions such as "Based on current climate trends, how will average global temperatures change by 2050?"

Here are examples of research questions across various disciplines, shedding light on queries that stimulate intellectual curiosity and advancement. In this post, we will delve into disciplines ranging from the Natural Sciences, such as Physics and Biology, to the Social Sciences, including Sociology and Anthropology, as well as the Humanities, like Literature and Philosophy. We'll also explore questions from fields as varied as Health Sciences, Engineering, Business, Environmental Sciences, Mathematics, Education, Law, Agriculture, Arts, Computer Science, Architecture, and Languages. This comprehensive overview aims to illustrate the breadth and depth of inquiries that shape our world of knowledge.

Agriculture and forestry examples

Architecture and planning examples, arts and design examples, business and finance examples, computer science and informatics examples, education examples, engineering and technology examples, environmental sciences examples, health sciences examples, humanities examples, languages and linguistics examples, law examples, mathematics and statistics examples, natural sciences examples, social sciences examples.

• Descriptive: What are the primary factors that influence crop yield in temperate climates?
• Explanatory: Why do certain soil types yield higher grain production than others?
• Exploratory: How might new organic farming techniques influence soil health over a decade?
• Comparative: How do the growth rates differ between genetically modified and traditional corn crops?
• Predictive: Based on current climate models, how will changing rain patterns impact wheat production in the next 20 years?

Animal science

• Descriptive: What are the common behavioral traits of domesticated cattle in grass-fed conditions?
• Explanatory: Why do certain breeds of chickens have a higher egg production rate?
• Exploratory: What potential benefits could arise from integrating tech wearables in livestock management?
• Comparative: How does the milk yield differ between Holstein and Jersey cows when given the same diet?
• Predictive: How might increasing global temperatures influence the reproductive cycles of swine?

Aquaculture

• Descriptive: What are the most commonly farmed fish species in Southeast Asia?
• Explanatory: Why do shrimp farms have a higher disease outbreak rate compared to fish farms?
• Exploratory: How might innovative recirculating aquaculture systems revolutionize the industry's environmental impact?
• Comparative: How do growth rates of salmon differ between open-net pens and land-based tanks?
• Predictive: What will be the impact of ocean acidification on mollusk farming over the next three decades?
• Descriptive: What tree species dominate the temperate rainforests of North America?
• Explanatory: Why are certain tree species more resistant to pest infestations?
• Exploratory: What are the potential benefits of integrating drone technology in forest health monitoring?
• Comparative: How do deforestation rates compare between legally protected and unprotected areas in the Amazon?
• Predictive: Given increasing global demand for timber, how might tree populations in Siberia change in the next half-century?

Horticulture

• Descriptive: What are the common characteristics of plants suitable for urban vertical farming?
• Explanatory: Why do roses require specific pH levels in the soil for optimal growth?
• Exploratory: What potential methods might promote year-round vegetable farming in colder regions?
• Comparative: How does fruit yield differ between traditionally planted orchards and high-density planting systems?
• Predictive: How might changing global temperatures affect wine grape production in traditional regions?

Soil science

• Descriptive: What are the main components of loamy soil?
• Explanatory: Why does clay-rich soil retain more water compared to sandy soil?
• Exploratory: How might biochar applications transform nutrient availability in degraded soils?
• Comparative: How do nutrient levels vary between soils managed with organic versus inorganic fertilizers?
• Predictive: Based on current farming practices, how will soil quality in the Midwest U.S. evolve over the next 30 years?

Architectural design

• Descriptive: What are the dominant architectural styles of public buildings constructed in the 21st century?
• Explanatory: Why do certain architectural elements from classical periods continue to influence modern designs?
• Exploratory: How might sustainable materials revolutionize the future of architectural design?
• Comparative: How do energy consumption levels differ between buildings with passive design elements and those without?
• Predictive: Based on urbanization trends, how will the design of residential buildings evolve in the next two decades?

Landscape architecture

• Descriptive: What are the primary components of a successful urban park design?
• Explanatory: Why do certain types of vegetation promote greater biodiversity in urban settings?
• Exploratory: What innovative techniques can be employed to restore and integrate wetlands into urban landscapes?
• Comparative: How does visitor satisfaction vary between nature-inspired landscapes and more structured, geometric designs?
• Predictive: With the effects of climate change, how might coastal landscape architecture adapt to rising sea levels over the coming century?

Urban planning

• Descriptive: What are the main components of a pedestrian-friendly city center?
• Explanatory: Why do certain urban layouts promote more efficient traffic flow than others?
• Exploratory: How might the integration of vertical farming impact urban food security and cityscape aesthetics?
• Comparative: How do the air quality levels differ between cities with green belts and those without?
• Predictive: Based on increasing telecommuting trends, how will urban planning strategies adjust to potentially reduced daily commutes in the future?

Graphic design

• Descriptive: What are the prevailing typography trends in modern branding?
• Explanatory: Why do certain color schemes evoke specific emotions or perceptions in consumers?
• Exploratory: How is augmented reality reshaping the landscape of interactive graphic design?
• Comparative: How do print and digital designs differ in terms of elements and principles when targeting a young adult audience?
• Predictive: Based on evolving digital platforms, what are potential future trends in web design aesthetics?

Industrial design

• Descriptive: What characterizes the ergonomic features of leading office chairs in the market?
• Explanatory: Why have minimalist designs become more prevalent in consumer electronics over the past decade?
• Exploratory: How might bio-inspired design influence the future of transportation vehicles?
• Comparative: How does user satisfaction differ between traditional versus modular product designs?
• Predictive: Given the push towards sustainability, how will material selection evolve in the next decade of product design?

Multimedia arts

• Descriptive: What techniques define the most popular virtual reality (VR) experiences currently available?
• Explanatory: Why do certain sound designs enhance immersion in video games more effectively than others?
• Exploratory: How might holographic technologies revolutionize stage performances or public installations in the future?
• Comparative: How do user engagement levels differ between 2D animations and 3D animations in educational platforms?
• Predictive: With the rise of augmented reality (AR) wearables, what might be the next frontier in multimedia art installations?

Performing arts

• Descriptive: What styles of dance are currently predominant in global theater productions?
• Explanatory: Why do certain rhythms or beats universally resonate with audiences across cultures?
• Exploratory: How might digital avatars or AI entities play roles in future theatrical performances?
• Comparative: How does audience reception differ between traditional plays and experimental, interactive performances?
• Predictive: Considering global digitalization, how might virtual theaters redefine the experience of live performances in the future?

Visual arts

• Descriptive: What themes are prevalent in contemporary art exhibitions worldwide?
• Explanatory: Why have mixed media installations gained prominence in the 21st-century art scene?
• Exploratory: How is the intersection of technology and art opening new mediums or platforms for artists?
• Comparative: How do traditional painting techniques, such as oil and watercolor, contrast in terms of texture and luminosity?
• Predictive: With the evolution of digital art platforms, how might the definition and appreciation of "original" artworks change in the coming years?

Entrepreneurship

• Descriptive: What are the main challenges faced by startups in the tech industry?
• Explanatory: Why do some entrepreneurial ventures succeed while others fail within their first five years?
• Exploratory: How are emerging digital platforms reshaping the entrepreneurial landscape?
• Comparative: How do funding opportunities for entrepreneurs differ between North America and Europe?
• Predictive: What sectors are predicted to see the most startup growth in the next decade?
• Descriptive: What are the primary sources of external funding for large corporations?
• Explanatory: Why did the stock market experience a significant drop in Q4 2022?
• Exploratory: How might blockchain technology revolutionize the future of banking?
• Comparative: How do the financial markets in developing countries compare to those in developed countries?
• Predictive: Based on current economic indicators, what is the forecasted health of the global economy for the next five years?

Human resources

• Descriptive: What are the most sought-after employee benefits in the tech industry?
• Explanatory: Why is there a high turnover rate in the retail sector?
• Exploratory: How might the rise of remote work affect HR practices in the next decade?
• Comparative: How do HR practices in multinational corporations differ from those in local companies?
• Predictive: What skills will be in highest demand in the workforce by 2030?
• Descriptive: What are the core responsibilities of middle management in large manufacturing firms?
• Explanatory: Why do some management strategies fail in diverse cultural environments?
• Exploratory: How are companies adapting their management structures in response to the gig economy?
• Comparative: How does management style in Eastern companies compare with Western businesses?
• Predictive: How might artificial intelligence reshape management practices in the next decade?
• Descriptive: What are the most effective digital marketing channels for e-commerce businesses?
• Explanatory: Why did a particular viral marketing campaign succeed in reaching a global audience?
• Exploratory: How might virtual reality change the landscape of product advertising?
• Comparative: How do marketing strategies differ between B2B and B2C sectors?
• Predictive: What consumer behaviors are forecasted to dominate online shopping trends in the next five years?

Operations research

• Descriptive: What are the primary optimization techniques used in supply chain management?
• Explanatory: Why do certain optimization algorithms perform better in specific industries?
• Exploratory: How can quantum computing impact the future of operations research?
• Comparative: How does operations strategy differ between service and manufacturing industries?
• Predictive: Based on current technological advancements, how might automation reshape supply chain strategies by 2035?

Artificial intelligence

• Descriptive: What are the primary algorithms used in deep learning?
• Explanatory: Why do certain neural network architectures outperform others in image recognition tasks?
• Exploratory: How might quantum computing influence the development of AI models?
• Comparative: How do reinforcement learning methods compare to supervised learning in game playing scenarios?
• Predictive: Based on current trends, how will AI impact the job market over the next decade?

Cybersecurity

• Descriptive: What are the most common types of cyberattacks reported in 2022?
• Explanatory: Why are certain industries more vulnerable to ransomware attacks?
• Exploratory: How might advances in quantum computing challenge existing encryption methods?
• Comparative: How do open-source software vulnerabilities compare to those in proprietary systems?
• Predictive: Given emerging technologies, what types of cyber threats will likely dominate in the next five years?

Data science

• Descriptive: What are the main tools used by data scientists in large-scale data analysis?
• Explanatory: Why does algorithm X yield more accurate predictions than algorithm Y for certain datasets?
• Exploratory: How can machine learning models improve real-time data processing in IoT devices?
• Comparative: How does the performance of traditional statistical models compare to machine learning models in predicting stock prices?
• Predictive: Based on current data trends, what industries will likely benefit the most from data analytics advancements in the coming decade?

Information systems

• Descriptive: What are the core components of a modern enterprise resource planning (ERP) system?
• Explanatory: Why have cloud-based information systems seen a rapid adoption rate in recent years?
• Exploratory: How might the integration of blockchain technology revolutionize supply chain information systems?
• Comparative: How do information system strategies differ between e-commerce and brick-and-mortar retailers?
• Predictive: Given the rise of remote work, how will information systems evolve to support decentralized teams in the future?

Software engineering

• Descriptive: What are the standard practices in agile software development?
• Explanatory: Why do some software projects face significant delays despite rigorous planning?
• Exploratory: How are emerging programming languages shaping the future of software development?
• Comparative: How does the software development lifecycle in startup environments compare to that in large corporations?
• Predictive: Based on current development trends, which software platforms are forecasted to dominate market share by 2030?

Adult education

• Descriptive: What are the primary motivations behind adults seeking further education later in life?
• Explanatory: Why do some adult education programs have a higher success rate compared to others?
• Exploratory: How might online learning platforms revolutionize adult education in the next decade?
• Comparative: How do adult education methodologies differ from traditional collegiate teaching techniques?
• Predictive: Given current trends, how will the demand for adult education courses change in the upcoming years?

Curriculum studies

• Descriptive: What are the core components of a modern high school curriculum in the United States?
• Explanatory: Why have certain subjects, like financial literacy, become more emphasized in recent curriculum updates?
• Exploratory: How can interdisciplinary studies be better incorporated into traditional curricula?
• Comparative: How does the math curriculum in the US compare to that in other developed countries?
• Predictive: Based on pedagogical research, what subjects are forecasted to gain prominence in curricula over the next decade?

Educational administration

• Descriptive: What are the main responsibilities of a school principal in large urban schools?
• Explanatory: Why do some schools consistently perform better in standardized testing than others, despite similar resources?
• Exploratory: How might emerging technologies shape the administrative tasks of educational institutions in the future?
• Comparative: How does school administration differ between private and public educational institutions?
• Predictive: Given the rise of online education, how will the role of educational administrators evolve in the coming years?

Educational psychology

• Descriptive: What cognitive strategies are commonly used by students to enhance memory retention during studies?
• Explanatory: Why do certain teaching methodologies resonate better with students having specific learning styles?
• Exploratory: How can insights from behavioral psychology improve student engagement in virtual classrooms?
• Comparative: How does the motivation level of students differ between self-paced versus instructor-led courses?
• Predictive: With the increasing integration of technology in education, how will student learning behaviors change in the next decade?

Special education

• Descriptive: What interventions are commonly used to support students with autism spectrum disorders in inclusive classrooms?
• Explanatory: Why do some special education programs yield better academic outcomes for students with specific learning disabilities?
• Exploratory: How can augmented reality technologies be utilized to enhance learning for students with visual impairments?
• Comparative: How does special education support differ between urban and rural school districts?
• Predictive: Based on advancements in assistive technologies, how will the landscape of special education transform in the near future?

Aerospace engineering

• Descriptive: What are the key materials and technologies utilized in modern spacecraft design?
• Explanatory: Why are certain alloys preferred in high-temperature aerospace applications?
• Exploratory: How might advances in propulsion technologies revolutionize space travel in the next decade?
• Comparative: How do commercial aircraft designs differ from military aircraft designs in terms of aerodynamics?
• Predictive: Given current research trends, how will the efficiency of jet engines change in the upcoming years?

Biomedical engineering

• Descriptive: What are the foundational principles behind the design of modern prosthetic limbs?
• Explanatory: Why have bio-compatible materials like titanium become crucial in implantable medical devices?
• Exploratory: How can nanotechnology be leveraged to improve drug delivery systems in the future?
• Comparative: How do MRI machines differ from CT scanners in terms of their underlying technology and application?
• Predictive: Based on emerging trends, how will wearable health monitors evolve in the next decade?

Chemical engineering

• Descriptive: What processes are involved in the large-scale production of ethylene?
• Explanatory: Why is distillation the most common separation method in the petroleum industry?
• Exploratory: How might green chemistry principles transform traditional chemical manufacturing processes?
• Comparative: How does the production of biofuels compare to traditional fossil fuels in terms of yield and environmental impact?
• Predictive: Given global sustainability goals, how will the chemical industry's reliance on fossil resources shift in the future?

Civil engineering

• Descriptive: What are the primary considerations in the structural design of skyscrapers in earthquake-prone regions?
• Explanatory: Why are steel-reinforced concrete beams commonly used in bridge construction?
• Exploratory: How can smart city concepts influence the infrastructure planning of urban centers in the future?
• Comparative: How do tunneling methods differ between soft soil and hard rock terrains?
• Predictive: With the increasing threat of climate change, how will coastal infrastructure design criteria change to account for rising sea levels?

Computer engineering

• Descriptive: What are the main components of a modern central processing unit (CPU) and their functions?
• Explanatory: Why is silicon predominantly used in semiconductor manufacturing?
• Exploratory: How might quantum computing redefine the landscape of traditional computing architectures?
• Comparative: How do solid-state drives (SSDs) compare to traditional hard disk drives (HDDs) in terms of performance and longevity?
• Predictive: Given advancements in chip miniaturization, how will the form factor of consumer electronics evolve in the coming years?

Electrical engineering

• Descriptive: What are the standard stages involved in the transmission and distribution of electrical power?
• Explanatory: Why are transformers essential in the power distribution network?
• Exploratory: How can emerging smart grid technologies improve the efficiency and reliability of electrical distribution systems?
• Comparative: How do AC and DC transmission methods differ in terms of efficiency and infrastructure requirements?
• Predictive: With the rise of renewable energy sources, how will power grid management complexities change in the next decade?

Mechanical engineering

• Descriptive: What are the fundamental principles behind the operation of a four-stroke internal combustion engine?
• Explanatory: Why are certain polymers used as vibration dampeners in machinery?
• Exploratory: How might advancements in materials science impact the design of future automotive systems?
• Comparative: How do hydraulic systems compare to pneumatic systems in terms of energy efficiency and application?
• Predictive: With the push towards sustainability, how will traditional manufacturing methods evolve to reduce their carbon footprint?

Climatology

• Descriptive: What are the primary factors that influence the El Niño and La Niña phenomena?
• Explanatory: Why have certain regions experienced more intense and frequent heatwaves in the past decade?
• Exploratory: How might changing atmospheric CO2 concentrations impact global wind patterns in the future?
• Comparative: How do urban areas differ from rural areas in terms of microclimate conditions?
• Predictive: Given current greenhouse gas emission trends, what will be the average global temperature increase by the end of the century?

Conservation science

• Descriptive: What are the primary threats faced by tropical rainforests around the world?
• Explanatory: Why are certain species more vulnerable to habitat fragmentation than others?
• Exploratory: How can community involvement enhance conservation efforts in protected areas?
• Comparative: How does the effectiveness of in-situ conservation compare to ex-situ conservation for endangered species?
• Predictive: If current deforestation rates continue, how many species are predicted to go extinct in the next 50 years?
• Descriptive: What are the dominant flora and fauna in a temperate deciduous forest biome?
• Explanatory: Why do certain ecosystems, like wetlands, have higher biodiversity than others?
• Exploratory: How might the spread of invasive species alter nutrient cycling in freshwater lakes?
• Comparative: How do the trophic dynamics of grassland ecosystems differ from those of desert ecosystems?
• Predictive: How will global ecosystems change if bee populations continue to decline at current rates?

Environmental health

• Descriptive: What are the major pollutants found in urban air?
• Explanatory: Why do certain pollutants cause respiratory diseases in humans?
• Exploratory: How might green building designs reduce the health risks associated with indoor air pollutants?
• Comparative: How do the health impacts of living near coal-fired power plants compare to living near nuclear power plants?
• Predictive: Given increasing urbanization trends, how will air quality in major cities change over the next two decades?

Marine biology

• Descriptive: What are the primary species that comprise a coral reef ecosystem?
• Explanatory: Why are coral reefs particularly sensitive to changes in sea temperature?
• Exploratory: How might deep-sea exploration reveal unknown marine species and their adaptations?
• Comparative: How do the feeding strategies of pelagic fish differ from benthic fish in oceanic ecosystems?
• Predictive: If ocean acidification trends continue, what will be the impact on shell-forming marine organisms in the next 30 years?
• Descriptive: What are the most common oral health issues faced by elderly individuals?
• Explanatory: Why do sugary foods lead to a higher prevalence of cavities?
• Exploratory: How might emerging technologies revolutionize dental procedures in the coming decade?
• Comparative: How do the effects of electric toothbrushes compare to manual ones in reducing plaque?
• Predictive: Given current trends, how might the prevalence of gum diseases change in populations with increased sugar consumption over the next decade?

Kinesiology

• Descriptive: What are the primary physiological changes that occur during aerobic exercise?
• Explanatory: Why do some athletes experience muscle cramps during extensive physical activity?
• Exploratory: How might different stretching routines impact athletic performance?
• Comparative: How do the biomechanics of running on a treadmill differ from running outdoors?
• Predictive: If sedentary lifestyles continue to rise, what could be the potential impact on musculoskeletal health in the next 20 years?
• Descriptive: What are the main symptoms associated with the early stages of Parkinson's disease?
• Explanatory: Why are some viruses, like the flu, more prevalent in colder months?
• Exploratory: How might genetic editing technologies, like CRISPR, be utilized to treat hereditary diseases in the future?
• Comparative: How does the efficacy of traditional chemotherapy compare to targeted therapy in treating certain cancers?
• Predictive: Given advances in telemedicine, how might patient-doctor interactions evolve over the next decade?
• Descriptive: What are the primary responsibilities of nurses in intensive care units?
• Explanatory: Why is there a higher burnout rate among nurses compared to other healthcare professionals?
• Exploratory: How can training programs be improved to better equip nurses for challenges in emergency situations?
• Comparative: How does the patient recovery rate differ when cared for by specialized nurses versus general ward nurses?
• Predictive: How will the role of nurses change with the integration of more AI-based diagnostic tools in hospitals?
• Descriptive: What are the main nutritional components of a Mediterranean diet?
• Explanatory: Why does a diet high in processed sugars lead to increased risks of type 2 diabetes?
• Exploratory: How might gut microbiota be influenced by various diets and what are the potential health implications?
• Comparative: How does the nutritional profile of plant-based proteins compare to animal-based proteins?
• Predictive: If global meat consumption trends continue, what could be the implications for population-wide nutritional health in 30 years?
• Descriptive: What are the primary active ingredients in over-the-counter pain relievers?
• Explanatory: Why do certain medications cause drowsiness as a side effect?
• Exploratory: How might nanoparticle-based drug delivery systems enhance the efficacy of certain treatments?
• Comparative: How do the effects of generic drugs compare to their brand-name counterparts?
• Predictive: Given the rise of antibiotic-resistant bacteria, how might pharmaceutical approaches to bacterial infections change in the future?

Public health

• Descriptive: What are the main factors contributing to public health disparities in urban vs rural areas?
• Explanatory: Why did certain regions have higher transmission rates during the COVID-19 pandemic?
• Exploratory: How can community engagement strategies be optimized for more effective health campaigns?
• Comparative: How do vaccination rates and outcomes differ between countries with public vs private healthcare systems?
• Predictive: Based on current trends, how will global public health challenges evolve over the next 50 years?

Art history

• Descriptive: What are the primary artistic styles observed in the Renaissance era?
• Explanatory: Why did the Baroque art movement emerge after the Renaissance?
• Exploratory: How might newly discovered ancient art pieces reshape our understanding of prehistoric artistic practices?
• Comparative: How does European Romantic art differ from Asian Romantic art of the same period?
• Predictive: Given current trends, how might digital art impact traditional art gallery setups in the next decade?
• Descriptive: What are the primary themes in Homer's "Odyssey"?
• Explanatory: Why did Greek tragedies place a strong emphasis on the concept of fate?
• Exploratory: Are there undiscovered works that might provide more insight into daily life in ancient Rome?
• Comparative: How do Roman epics compare to their Greek counterparts in terms of character development?
• Predictive: How will emerging technologies like virtual reality affect the study of ancient ruins?

Cultural studies

• Descriptive: How is the concept of family portrayed in contemporary American media?
• Explanatory: Why has the influence of Western culture grown in certain Eastern countries over the last century?
• Exploratory: What are the emerging subcultures in the digital age and how do they communicate?
• Comparative: How does the representation of masculinity vary between Eastern and Western films?
• Predictive: In what ways might globalization affect cultural identities in the next two decades?
• Descriptive: What events led to the fall of the Berlin Wall?
• Explanatory: Why did the Industrial Revolution begin in Britain?
• Exploratory: Are there undocumented civilizational interactions in ancient times that new archaeological findings might reveal?
• Comparative: How did the responses to the Black Plague differ between European and Asian nations?
• Predictive: Given historical patterns, how might major global powers react to dwindling natural resources in the future?
• Descriptive: What are the main narrative techniques used in James Joyce's "Ulysses"?
• Explanatory: Why did the Gothic novel become popular in 19th-century England?
• Exploratory: How might translations of ancient texts reveal different interpretations based on the translator's cultural background?
• Comparative: How does the portrayal of war differ between post-WWII American and French literature?
• Predictive: How might the rise of AI-authored literature change the publishing industry?
• Descriptive: What are the core principles of existentialism as described by Jean-Paul Sartre?
• Explanatory: Why did the philosophy of existentialism gain prominence post-WWII?
• Exploratory: How might ancient Eastern philosophies provide insights into modern ethical dilemmas surrounding technology?
• Comparative: How does Nietzsche's concept of the "Ubermensch" compare to Aristotle's "virtuous person"?
• Predictive: As AI becomes more prevalent, how might philosophical discussions around consciousness evolve?

Religious studies

• Descriptive: What are the Five Pillars of Islam?
• Explanatory: Why did Protestantism emerge within Christianity during the 16th century?
• Exploratory: Are there common motifs in creation myths across various religions?
• Comparative: How do concepts of the afterlife compare between Christianity, Buddhism, and Ancient Egyptian beliefs?
• Predictive: How might interfaith dialogue shape religious practices in multi-faith societies over the next decade?

Classic languages

• Descriptive: What are the primary grammatical structures in Ancient Greek?
• Explanatory: Why did Latin play a foundational role in the development of many modern European languages?
• Exploratory: Are there yet-to-be-deciphered scripts from ancient civilizations that might provide insight into lost languages?
• Comparative: How do the verb conjugation patterns in Latin compare to those in Sanskrit?
• Predictive: Given the ongoing research in classical studies, how might our understanding of certain ancient texts change in the next decade?

Comparative literature

• Descriptive: What are the main themes in Japanese Haiku and English Sonnets?
• Explanatory: Why do certain folklore tales appear with variations across different cultures?
• Exploratory: How might newly translated works from lesser-known languages reshape the world literature canon?
• Comparative: How does the role of the tragic hero in French literature differ from its portrayal in Russian literature?
• Predictive: As global communication becomes more interconnected, how might the study of world literature evolve in universities?

Modern languages

• Descriptive: What are the primary tonal patterns observed in Mandarin Chinese?
• Explanatory: Why has English become a dominant lingua franca in international business and diplomacy?
• Exploratory: Which lesser-studied languages might become more prominent due to socio-political changes in their regions?
• Comparative: How do the grammatical complexities of Russian compare to those of German?
• Predictive: Given current global trends, which languages are predicted to become more widely spoken in the next two decades?
• Descriptive: What are the primary articulatory features of plosive sounds?
• Explanatory: Why do certain accents develop specific pitch fluctuations and intonations?
• Exploratory: How do various environmental factors affect vocal cord vibrations and sound production?
• Comparative: How does the pronunciation of fricatives differ between Spanish and Portuguese speakers?
• Predictive: How might advancements in voice recognition technology influence phonetics research in the next decade?
• Descriptive: What are the primary signs and symbols used in American road signage?
• Explanatory: Why do red roses universally symbolize love or passion in many cultures?
• Exploratory: Are there emerging symbols in digital communication that could become universally recognized signs in the future?
• Comparative: How do the semiotic structures in print advertisements differ between Western and Eastern cultures?
• Predictive: As emoji usage becomes more widespread, how might they impact written language semantics in the coming years?
• Descriptive: What are the key statutes governing tenant rights in residential leases?
• Explanatory: Why do personal injury claims vary significantly in settlement amounts even under similar circumstances?
• Exploratory: How might alternative dispute resolution mechanisms evolve in civil law contexts over the next decade?
• Comparative: How do defamation laws differ between jurisdictions that adopt the British common law system versus the Napoleonic code?
• Predictive: How might the rise of online transactions affect the volume and nature of civil law cases related to contract disputes?

Constitutional law

• Descriptive: What are the main principles enshrined in the First Amendment of the U.S. Constitution?
• Explanatory: Why have some constitutional rights been subject to varying interpretations over time?
• Exploratory: Are there emerging debates around digital rights and freedoms that might reshape constitutional interpretations in the future?
• Comparative: How does the protection of freedom of speech differ between the U.S. Constitution and the German Basic Law?
• Predictive: Given global socio-political trends, how might constitutional democracies adjust their foundational texts in the next two decades?

Corporate law

• Descriptive: What are the primary duties and liabilities of a board of directors in a publicly traded company?
• Explanatory: Why do mergers and acquisitions often involve extensive due diligence processes?
• Exploratory: How might the rise of digital currencies impact the regulatory landscape for corporations in the finance sector?
• Comparative: How does the legal framework for shareholder rights in the U.S. compare to that of Japan?
• Predictive: How might changing global trade dynamics influence corporate structuring and international partnerships?

Criminal law

• Descriptive: What constitutes first-degree murder in the majority of jurisdictions?
• Explanatory: Why are certain offenses classified as misdemeanors while others are felonies?
• Exploratory: Are there emerging patterns in cybercrime that suggest new areas of legal vulnerability?
• Comparative: How does the treatment of juvenile offenders differ between Scandinavian countries and the U.S.?
• Predictive: Given advancements in technology, how might criminal law evolve to address potential misuses of artificial intelligence?

International law

• Descriptive: What are the foundational principles of the Geneva Conventions?
• Explanatory: Why have some nations refused to recognize or be bound by certain international treaties?
• Exploratory: How might global climate change reshape international agreements and treaties in the coming years?
• Comparative: How do regional trade agreements in Africa compare to those in Southeast Asia in terms of provisions and enforcement mechanisms?
• Predictive: How might geopolitical shifts influence the role and effectiveness of international courts in resolving state disputes?

Applied mathematics

• Descriptive: What are the primary mathematical models used to predict the spread of infectious diseases?
• Explanatory: Why does the Navier–Stokes equation play a pivotal role in fluid dynamics?
• Exploratory: How might new computational methods enhance the efficiency of existing algorithms in applied mathematics?
• Comparative: How do optimization techniques in operations research differ from those in machine learning applications?
• Predictive: Given the rapid growth of quantum computing, how might it reshape the landscape of applied mathematical problems in the next decade?

Applied statistics

• Descriptive: What are the standard procedures for handling missing data in a large-scale survey?
• Explanatory: Why do statisticians use bootstrapping techniques in hypothesis testing?
• Exploratory: How might emerging data sources, like wearables and IoT devices, introduce new challenges and opportunities in applied statistics?
• Comparative: How does the performance of Bayesian methods compare to frequentist methods in complex hierarchical models?
• Predictive: With the increasing availability of big data, how might the role of applied statisticians evolve in the next five years?

Pure mathematics

• Descriptive: What are the axioms underpinning Euclidean geometry?
• Explanatory: Why is Gödel's incompleteness theorem considered a foundational result in the philosophy of mathematics?
• Exploratory: Are there newly emerging areas of study within number theory due to advancements in computational mathematics?
• Comparative: How do algebraic structures differ between rings and fields?
• Predictive: Considering current research trends, what areas of pure mathematics are poised for significant breakthroughs in the next decade?

Theoretical statistics

• Descriptive: What foundational principles underlie the Central Limit Theorem?
• Explanatory: Why is the concept of sufficiency crucial in the design of statistical tests?
• Exploratory: How might advances in artificial intelligence influence theoretical developments in statistical inference?
• Comparative: How do likelihood-based inference methods compare to Bayesian methods in terms of theoretical underpinnings?
• Predictive: As data generation mechanisms evolve, how might the theoretical foundations of statistics need to adapt in the future?
• Descriptive: What are the key features and behaviors of black holes?
• Explanatory: Why does the expansion of the universe appear to be accelerating?
• Exploratory: What potential insights might the study of exoplanets provide about the conditions necessary for life?
• Comparative: How do the properties of spiral galaxies differ from those of elliptical galaxies?
• Predictive: Based on current data, what are the projected future behaviors of our sun as it ages?
• Descriptive: What are the primary functions and structures of ribosomes in a cell?
• Explanatory: Why does DNA replication occur semi-conservatively?
• Exploratory: How might emerging technologies like CRISPR redefine our understanding of genetic engineering?
• Comparative: How do the metabolic processes of prokaryotic cells differ from those of eukaryotic cells?
• Predictive: Given the current trajectory of climate change, how might the biodiversity in tropical rainforests be affected over the next century?
• Descriptive: What are the key properties and uses of the noble gases?
• Explanatory: Why do exothermic reactions release heat?
• Exploratory: How might advances in nanochemistry influence drug delivery systems?
• Comparative: How do ionic bonds differ in strength and characteristics from covalent bonds?
• Predictive: Considering the rise in antibiotic-resistant bacteria, how might the field of medicinal chemistry adapt to produce effective treatments in the future?

Earth science

• Descriptive: What are the primary layers of Earth's atmosphere and their respective characteristics?
• Explanatory: Why do certain regions experience more seismic activity than others?
• Exploratory: How might the study of ancient ice cores provide insights into past climate conditions?
• Comparative: How do the processes of weathering differ between arid and humid climates?
• Predictive: Given current data on deforestation, what could be its impact on global soil quality and erosion patterns over the next 50 years?
• Descriptive: What are the fundamental principles underlying quantum mechanics?
• Explanatory: Why does the speed of light in a vacuum remain constant regardless of the observer's frame of reference?
• Exploratory: How might studies in string theory reshape our understanding of the universe at the smallest scales?
• Comparative: How do the effects of general relativity contrast with predictions from Newtonian physics under extreme gravitational conditions?
• Predictive: With advancements in particle physics, what potential new particles or phenomena might be discovered in the next decade?

Anthropology

• Descriptive: What are the primary rituals and customs of the indigenous tribes of the Amazon?
• Explanatory: Why did the ancient Mayan civilization collapse?
• Exploratory: How might modern urbanization impact the preservation of ancient burial sites?
• Comparative: How do hunter-gatherer societies differ from agricultural societies in terms of social structures?
• Predictive: Given global trends, how might indigenous cultures evolve over the next century?

Communication

• Descriptive: What are the main modes of communication used by millennials compared to baby boomers?
• Explanatory: Why has the usage of social media platforms surged in the last two decades?
• Exploratory: How might advancements in virtual reality reshape interpersonal communication in the future?
• Comparative: How do written communication skills differ between those educated in traditional schools versus online schools?
• Predictive: How might the nature of journalism change with the rise of automated content generation?
• Descriptive: What are the primary components of a nation's gross domestic product (GDP)?
• Explanatory: Why did the economic recession of 2008 occur?
• Exploratory: How might the concept of universal basic income impact labor market dynamics?
• Comparative: How do free market economies differ from command economies in terms of resource allocation?
• Predictive: Based on current global economic trends, which industries are predicted to boom in the next decade?
• Descriptive: What are the geographical features of the Himalayan mountain range?
• Explanatory: Why do desert regions exist on the western coasts of continents, such as the Atacama in South America?
• Exploratory: How might rising sea levels reshape the world's coastlines over the next century?
• Comparative: How does urban planning in European cities differ from that in American cities?
• Predictive: Given current urbanization rates, which cities are poised to become megacities by 2050?

Political science

• Descriptive: What are the foundational principles of a parliamentary democracy?
• Explanatory: Why do certain nations adopt federal systems while others prefer unitary systems?
• Exploratory: How might the rise of populism influence global diplomatic relations in the 21st century?
• Comparative: How do the rights of citizens in liberal democracies differ from those in authoritarian regimes?
• Predictive: Based on current political trends, which nations might see significant shifts in governance models over the next two decades?
• Descriptive: What are the primary stages of cognitive development in children according to Piaget?
• Explanatory: Why do certain individuals develop phobias?
• Exploratory: How might emerging neuroscientific tools, like fMRI, alter our understanding of human emotions?
• Comparative: How do coping mechanisms differ between individuals with high resilience versus those with low resilience?
• Predictive: Given the rise in digital communication, how might human attention spans evolve in future generations?

Social work

• Descriptive: What are the core principles and practices in child protective services?
• Explanatory: Why do certain communities have higher rates of child neglect and abuse?
• Exploratory: How might the integration of artificial intelligence in social work affect decision-making in child welfare cases?
• Comparative: How do intervention strategies for substance abuse differ between urban and rural settings?
• Predictive: Based on current societal trends, what challenges might social workers face in the next decade?
• Descriptive: What are the defining characteristics of Generation Z as a social cohort?
• Explanatory: Why have nuclear families become less prevalent in Western societies?
• Exploratory: How might the widespread adoption of virtual realities impact social interactions and community structures in the future?
• Comparative: How do the roles and perceptions of elderly individuals differ between Eastern and Western societies?
• Predictive: Given the rise in remote work, how might urban and suburban living patterns change over the next three decades?

In synthesizing the vast range of research questions posed across diverse disciplines, it becomes clear that every academic field, from the humanities to the social sciences, offers unique perspectives and methodologies to uncover and understand various facets of our world. These questions, whether descriptive, explanatory, exploratory, comparative, or predictive, serve as guiding lights, driving scholarship and innovation. As academia continues to evolve and adapt, these inquiries not only define the boundaries of current knowledge but also pave the way for future discoveries and insights, emphasizing the invaluable role of continuous inquiry in the ever-evolving tapestry of human understanding.

Header image by Zetong Li .

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Basic vs. applied research: what’s the difference?

Last updated

27 February 2023

Reviewed by

Cathy Heath

Research can be used to learn new facts, create new products, and solve various problems. Yet, there are different ways to undertake research to meet a desired goal. 

The method you choose to conduct research will most likely be based on what question you want to answer, plus other factors that will help you accurately get the answer you need. 

Research falls into two main categories: basic research and applied research. Both types of research have distinct purposes and varied benefits. 

This guide will help you understand the differences and similarities between basic and applied research and how they're used. It also answers common questions about the two types of research, including:

Why is it called basic research?

What is more important, basic research or applied research?

What are examples of pure (basic) research and applied research?

Analyze basic and applied research

Dovetail streamlines analysis to help you uncover and share actionable insights

• What is basic research?

Basic research (sometimes called fundamental or pure) advances scientific knowledge to completely understand a subject, topic, or phenomenon. It's conducted to satisfy curiosity or develop a full body of knowledge on a specific subject.

Basic research is used to bring about a fundamental understanding of the world, different behaviors, and is the foundation of knowledge in the scientific disciplines. It is usually conducted based on developing and testing theories.

While there is no apparent commercial value to the discoveries that result from basic research, it is the foundation of research used for other projects like developing solutions to solve problems. 

Examples of basic research

Basic research has always been used to give humans a better understanding of all branches of science and knowledge. However, it's not specifically based on identifying new things about the universe.

Basic research has a wide range of uses, as shown in the following examples:

Investigation into how the universe began

A study searching for the causes of cancer

Understanding the components that make up human DNA

An examination into whether a vegetarian diet is healthier than one with meat

A study to learn more about which areas in the world get the most precipitation

Benefits of conducting basic research

Called basic research because it is performed without an immediate or obvious benefit, this type of research often leads to vital solutions in the future. While basic research isn't technically solution-driven, it develops the underlying knowledge used for additional learning and research. 

There are many benefits derived from basic research, including:

Gaining an understanding of living systems and the environment

Gathering information that can help society prepare for the future

Expanding knowledge that can lead to medical advances

Providing a foundation for applied research

• What is applied research?

Applied research studies particular circumstances to apply the information to real-life situations. It helps improve the human condition by finding practical solutions for existing problems.

Applied research builds off facts derived from basic research and other data to address challenges in all facets of life. Instead of exploring theories of the unknown, applied research requires researchers to use existing knowledge, facts, and discoveries to generate new knowledge. 

Solutions derived from applied research are used in situations ranging from medical treatments or product development to new laws or regulations.

Examples of applied research

Applied research is designed to solve practical problems that exist under current conditions. However, it's not only used for consumer-based products and decisions.

Applied research can be used in a variety of ways, as illustrated by the following examples:

The investigation of ways to improve agricultural crop production

A study to improve methods to market products for Gen Z consumers

Examination of how technology can t make car tires last longer

Exploration of how to cook healthy meals with a limited budget

A study on how to treat patients with insomnia

Benefits of using applied research

Although applied research expands upon a foundation of existing knowledge, it also brings about new ideas. Applied research provides many benefits in various circumstances, including:

Designing new products and services

Creating new objectives

Providing unbiased data through the testing of verifiable evidence

• Basic research vs. applied research: the differences

Both basic and applied research are tactics for discovering specific information. However, they differ significantly in the way research is conducted and the objectives they achieve. 

Some of the most notable differences between basic and applied research include the following:

Research outcomes: curiosity-driven vs. solution-driven

Basic research is generally conducted to learn more about a specific subject. It is usually self-initiated to gain knowledge to satisfy curiosity or confirm a theory. 

Conversely, applied knowledge is directed toward finding a solution to a specific problem. It is often conducted to assist a client in improving products, services, or issues.

Research scope: universal scope vs. specific scope

Basic research uses a broad scope to apply various concepts to gain more knowledge. Research methods may include studying different subjects to add more information that connects evidence points in a greater body of data.

Meanwhile, applied research depends on a specific or narrow scope to gather specific evidence to address a certain problem.

Research approaches: expanding existing knowledge vs. finding new knowledge

Researchers conduct basic research to fill in gaps between existing information points. Basic knowledge is an expansion of existing knowledge to gain a deeper understanding. It is often based on how, what, or why something is the way it is. Although applied research may be based on information derived from basic research, it's not designed to expand the knowledge. Instead, the research is conducted to find new knowledge, usually in the form of a solution.

Research commercialization: Informational vs. commercial gain

The main basis of product development is to solve a problem for consumers.

Basic research might lead to solutions and commercial products in the future to help with this. Since applied research is used to develop solutions, it's often used for commercial gain.

Theory formulation: theoretical vs. practical nature

Basic research is usually based on a theory about a specific subject. Researchers may develop a theory that grows and changes as more information is discovered during the research process. Conversely, applied research is practical in nature since the goal is to solve a specific problem.

• Are there similarities between applied and basic research?

While some obvious differences exist, applied and basic research methods have similarities. For example, researchers may use the same methods to collect data (like interviews, surveys , and focus groups ) for both types of research. 

Both types of research require researchers to use inductive and deductive reasoning to develop and prove hypotheses . The two types of research frequently intersect when basic research serves as the foundation for applied research.

While applied research is solution-based, basic research is equally important because it yields information used to develop solutions to many types of problems. 

• Methods used in basic research and applied research

While basic and applied research have different approaches and goals, they require researchers or scientists to gather data. Basic and applied research makes use of many of the same methods to gather and study information, including the following:

Observations: Studying research subjects for an extended time allows researchers to gather information about how subjects behave under different conditions.

Interviews: Surveys and one-to-one discussions help researchers gain information from other subjects and validate data.

Experiments: Researchers conduct experiments to prove or disprove certain hypotheses based on information that has been gathered.

Questionnaires: A series of questions related to the research context helps researchers gather quantitative information applicable to both basic and applied research.

• How do you determine when to use basic research vs. applied research?

Basic and applied research are both helpful in obtaining knowledge. However, they aren't usually used in the same settings or under the same circumstances. 

When you're trying to determine which type of research to use for a particular project, it's essential to consider your product goals. Basic research seeks answers to universal, theoretical questions. While it works to uncover specific knowledge, it's generally not used to develop a solution. Conversely, applied research discovers answers to specific questions. It should be used to find out new knowledge to solve a problem.

• Bottom line

Both basic and applied research are methods used to gather information and analyze facts that help build knowledge around a subject. However, basic research is used to gain understanding and satisfy curiosity, while applied research is used to solve specific problems. Both types of research depend on gathering information to prove a hypothesis or create a product, service, or valuable process. 

By learning more about the similarities and differences between basic and applied research, you'll be prepared to gather and use data efficiently to meet your needs.

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There are three basic types of questions that research projects can address:

• Descriptive. When a study is designed primarily to describe what is going on or what exists. Public opinion polls that seek only to describe the proportion of people who hold various opinions are primarily descriptive in nature. For instance, if we want to know what percent of the population would vote for a Democratic or a Republican in the next presidential election, we are simply interested in describing something.
• Relational. When a study is designed to look at the relationships between two or more variables. A public opinion poll that compares what proportion of males and females say they would vote for a Democratic or a Republican candidate in the next presidential election is essentially studying the relationship between gender and voting preference.
• Causal. When a study is designed to determine whether one or more variables (e.g. a program or treatment variable) causes or affects one or more outcome variables. If we did a public opinion poll to try to determine whether a recent political advertising campaign changed voter preferences, we would essentially be studying whether the campaign (cause) changed the proportion of voters who would vote Democratic or Republican (effect).

The three question types can be viewed as cumulative. That is, a relational study assumes that you can first describe (by measuring or observing) each of the variables you are trying to relate. And, a causal study assumes that you can describe both the cause and effect variables and that you can show that they are related to each other. Causal studies are probably the most demanding of the three.

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Cultural Relativity and Acceptance of Embryonic Stem Cell Research

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There is a debate about the ethical implications of using human embryos in stem cell research, which can be influenced by cultural, moral, and social values. This paper argues for an adaptable framework to accommodate diverse cultural and religious perspectives. By using an adaptive ethics model, research protections can reflect various populations and foster growth in stem cell research possibilities.

INTRODUCTION

Stem cell research combines biology, medicine, and technology, promising to alter health care and the understanding of human development. Yet, ethical contention exists because of individuals’ perceptions of using human embryos based on their various cultural, moral, and social values. While these disagreements concerning policy, use, and general acceptance have prompted the development of an international ethics policy, such a uniform approach can overlook the nuanced ethical landscapes between cultures. With diverse viewpoints in public health, a single global policy, especially one reflecting Western ethics or the ethics prevalent in high-income countries, is impractical. This paper argues for a culturally sensitive, adaptable framework for the use of embryonic stem cells. Stem cell policy should accommodate varying ethical viewpoints and promote an effective global dialogue. With an extension of an ethics model that can adapt to various cultures, we recommend localized guidelines that reflect the moral views of the people those guidelines serve.

Stem cells, characterized by their unique ability to differentiate into various cell types, enable the repair or replacement of damaged tissues. Two primary types of stem cells are somatic stem cells (adult stem cells) and embryonic stem cells. Adult stem cells exist in developed tissues and maintain the body’s repair processes. [1] Embryonic stem cells (ESC) are remarkably pluripotent or versatile, making them valuable in research. [2] However, the use of ESCs has sparked ethics debates. Considering the potential of embryonic stem cells, research guidelines are essential. The International Society for Stem Cell Research (ISSCR) provides international stem cell research guidelines. They call for “public conversations touching on the scientific significance as well as the societal and ethical issues raised by ESC research.” [3] The ISSCR also publishes updates about culturing human embryos 14 days post fertilization, suggesting local policies and regulations should continue to evolve as ESC research develops. [4]  Like the ISSCR, which calls for local law and policy to adapt to developing stem cell research given cultural acceptance, this paper highlights the importance of local social factors such as religion and culture.

I.     Global Cultural Perspective of Embryonic Stem Cells

Views on ESCs vary throughout the world. Some countries readily embrace stem cell research and therapies, while others have stricter regulations due to ethical concerns surrounding embryonic stem cells and when an embryo becomes entitled to moral consideration. The philosophical issue of when the “someone” begins to be a human after fertilization, in the morally relevant sense, [5] impacts when an embryo becomes not just worthy of protection but morally entitled to it. The process of creating embryonic stem cell lines involves the destruction of the embryos for research. [6] Consequently, global engagement in ESC research depends on social-cultural acceptability.

a.     US and Rights-Based Cultures

In the United States, attitudes toward stem cell therapies are diverse. The ethics and social approaches, which value individualism, [7] trigger debates regarding the destruction of human embryos, creating a complex regulatory environment. For example, the 1996 Dickey-Wicker Amendment prohibited federal funding for the creation of embryos for research and the destruction of embryos for “more than allowed for research on fetuses in utero.” [8] Following suit, in 2001, the Bush Administration heavily restricted stem cell lines for research. However, the Stem Cell Research Enhancement Act of 2005 was proposed to help develop ESC research but was ultimately vetoed. [9] Under the Obama administration, in 2009, an executive order lifted restrictions allowing for more development in this field. [10] The flux of research capacity and funding parallels the different cultural perceptions of human dignity of the embryo and how it is socially presented within the country’s research culture. [11]

b.     Ubuntu and Collective Cultures

African bioethics differs from Western individualism because of the different traditions and values. African traditions, as described by individuals from South Africa and supported by some studies in other African countries, including Ghana and Kenya, follow the African moral philosophies of Ubuntu or Botho and Ukama , which “advocates for a form of wholeness that comes through one’s relationship and connectedness with other people in the society,” [12] making autonomy a socially collective concept. In this context, for the community to act autonomously, individuals would come together to decide what is best for the collective. Thus, stem cell research would require examining the value of the research to society as a whole and the use of the embryos as a collective societal resource. If society views the source as part of the collective whole, and opposes using stem cells, compromising the cultural values to pursue research may cause social detachment and stunt research growth. [13] Based on local culture and moral philosophy, the permissibility of stem cell research depends on how embryo, stem cell, and cell line therapies relate to the community as a whole . Ubuntu is the expression of humanness, with the person’s identity drawn from the “’I am because we are’” value. [14] The decision in a collectivistic culture becomes one born of cultural context, and individual decisions give deference to others in the society.

Consent differs in cultures where thought and moral philosophy are based on a collective paradigm. So, applying Western bioethical concepts is unrealistic. For one, Africa is a diverse continent with many countries with different belief systems, access to health care, and reliance on traditional or Western medicines. Where traditional medicine is the primary treatment, the “’restrictive focus on biomedically-related bioethics’” [is] problematic in African contexts because it neglects bioethical issues raised by traditional systems.” [15] No single approach applies in all areas or contexts. Rather than evaluating the permissibility of ESC research according to Western concepts such as the four principles approach, different ethics approaches should prevail.

Another consideration is the socio-economic standing of countries. In parts of South Africa, researchers have not focused heavily on contributing to the stem cell discourse, either because it is not considered health care or a health science priority or because resources are unavailable. [16] Each country’s priorities differ given different social, political, and economic factors. In South Africa, for instance, areas such as maternal mortality, non-communicable diseases, telemedicine, and the strength of health systems need improvement and require more focus. [17] Stem cell research could benefit the population, but it also could divert resources from basic medical care. Researchers in South Africa adhere to the National Health Act and Medicines Control Act in South Africa and international guidelines; however, the Act is not strictly enforced, and there is no clear legislation for research conduct or ethical guidelines. [18]

Some parts of Africa condemn stem cell research. For example, 98.2 percent of the Tunisian population is Muslim. [19] Tunisia does not permit stem cell research because of moral conflict with a Fatwa. Religion heavily saturates the regulation and direction of research. [20] Stem cell use became permissible for reproductive purposes only recently, with tight restrictions preventing cells from being used in any research other than procedures concerning ART/IVF.  Their use is conditioned on consent, and available only to married couples. [21] The community's receptiveness to stem cell research depends on including communitarian African ethics.

c.     Asia

Some Asian countries also have a collective model of ethics and decision making. [22] In China, the ethics model promotes a sincere respect for life or human dignity, [23] based on protective medicine. This model, influenced by Traditional Chinese Medicine (TCM), [24] recognizes Qi as the vital energy delivered via the meridians of the body; it connects illness to body systems, the body’s entire constitution, and the universe for a holistic bond of nature, health, and quality of life. [25] Following a protective ethics model, and traditional customs of wholeness, investment in stem cell research is heavily desired for its applications in regenerative therapies, disease modeling, and protective medicines. In a survey of medical students and healthcare practitioners, 30.8 percent considered stem cell research morally unacceptable while 63.5 percent accepted medical research using human embryonic stem cells. Of these individuals, 89.9 percent supported increased funding for stem cell research. [26] The scientific community might not reflect the overall population. From 1997 to 2019, China spent a total of $576 million (USD) on stem cell research at 8,050 stem cell programs, increased published presence from 0.6 percent to 14.01 percent of total global stem cell publications as of 2014, and made significant strides in cell-based therapies for various medical conditions. [27] However, while China has made substantial investments in stem cell research and achieved notable progress in clinical applications, concerns linger regarding ethical oversight and transparency. [28] For example, the China Biosecurity Law, promoted by the National Health Commission and China Hospital Association, attempted to mitigate risks by introducing an institutional review board (IRB) in the regulatory bodies. 5800 IRBs registered with the Chinese Clinical Trial Registry since 2021. [29] However, issues still need to be addressed in implementing effective IRB review and approval procedures.

The substantial government funding and focus on scientific advancement have sometimes overshadowed considerations of regional cultures, ethnic minorities, and individual perspectives, particularly evident during the one-child policy era. As government policy adapts to promote public stability, such as the change from the one-child to the two-child policy, [30] research ethics should also adapt to ensure respect for the values of its represented peoples.

Japan is also relatively supportive of stem cell research and therapies. Japan has a more transparent regulatory framework, allowing for faster approval of regenerative medicine products, which has led to several advanced clinical trials and therapies. [31] South Korea is also actively engaged in stem cell research and has a history of breakthroughs in cloning and embryonic stem cells. [32] However, the field is controversial, and there are issues of scientific integrity. For example, the Korean FDA fast-tracked products for approval, [33] and in another instance, the oocyte source was unclear and possibly violated ethical standards. [34] Trust is important in research, as it builds collaborative foundations between colleagues, trial participant comfort, open-mindedness for complicated and sensitive discussions, and supports regulatory procedures for stakeholders. There is a need to respect the culture’s interest, engagement, and for research and clinical trials to be transparent and have ethical oversight to promote global research discourse and trust.

d.     Middle East

Countries in the Middle East have varying degrees of acceptance of or restrictions to policies related to using embryonic stem cells due to cultural and religious influences. Saudi Arabia has made significant contributions to stem cell research, and conducts research based on international guidelines for ethical conduct and under strict adherence to guidelines in accordance with Islamic principles. Specifically, the Saudi government and people require ESC research to adhere to Sharia law. In addition to umbilical and placental stem cells, [35] Saudi Arabia permits the use of embryonic stem cells as long as they come from miscarriages, therapeutic abortions permissible by Sharia law, or are left over from in vitro fertilization and donated to research. [36] Laws and ethical guidelines for stem cell research allow the development of research institutions such as the King Abdullah International Medical Research Center, which has a cord blood bank and a stem cell registry with nearly 10,000 donors. [37] Such volume and acceptance are due to the ethical ‘permissibility’ of the donor sources, which do not conflict with religious pillars. However, some researchers err on the side of caution, choosing not to use embryos or fetal tissue as they feel it is unethical to do so. [38]

Jordan has a positive research ethics culture. [39] However, there is a significant issue of lack of trust in researchers, with 45.23 percent (38.66 percent agreeing and 6.57 percent strongly agreeing) of Jordanians holding a low level of trust in researchers, compared to 81.34 percent of Jordanians agreeing that they feel safe to participate in a research trial. [40] Safety testifies to the feeling of confidence that adequate measures are in place to protect participants from harm, whereas trust in researchers could represent the confidence in researchers to act in the participants’ best interests, adhere to ethical guidelines, provide accurate information, and respect participants’ rights and dignity. One method to improve trust would be to address communication issues relevant to ESC. Legislation surrounding stem cell research has adopted specific language, especially concerning clarification “between ‘stem cells’ and ‘embryonic stem cells’” in translation. [41] Furthermore, legislation “mandates the creation of a national committee… laying out specific regulations for stem-cell banking in accordance with international standards.” [42] This broad regulation opens the door for future global engagement and maintains transparency. However, these regulations may also constrain the influence of research direction, pace, and accessibility of research outcomes.

e.     Europe

In the European Union (EU), ethics is also principle-based, but the principles of autonomy, dignity, integrity, and vulnerability are interconnected. [43] As such, the opportunity for cohesion and concessions between individuals’ thoughts and ideals allows for a more adaptable ethics model due to the flexible principles that relate to the human experience The EU has put forth a framework in its Convention for the Protection of Human Rights and Dignity of the Human Being allowing member states to take different approaches. Each European state applies these principles to its specific conventions, leading to or reflecting different acceptance levels of stem cell research. [44]

For example, in Germany, Lebenzusammenhang , or the coherence of life, references integrity in the unity of human culture. Namely, the personal sphere “should not be subject to external intervention.” [45]  Stem cell interventions could affect this concept of bodily completeness, leading to heavy restrictions. Under the Grundgesetz, human dignity and the right to life with physical integrity are paramount. [46] The Embryo Protection Act of 1991 made producing cell lines illegal. Cell lines can be imported if approved by the Central Ethics Commission for Stem Cell Research only if they were derived before May 2007. [47] Stem cell research respects the integrity of life for the embryo with heavy specifications and intense oversight. This is vastly different in Finland, where the regulatory bodies find research more permissible in IVF excess, but only up to 14 days after fertilization. [48] Spain’s approach differs still, with a comprehensive regulatory framework. [49] Thus, research regulation can be culture-specific due to variations in applied principles. Diverse cultures call for various approaches to ethical permissibility. [50] Only an adaptive-deliberative model can address the cultural constructions of self and achieve positive, culturally sensitive stem cell research practices. [51]

II.     Religious Perspectives on ESC

Embryonic stem cell sources are the main consideration within religious contexts. While individuals may not regard their own religious texts as authoritative or factual, religion can shape their foundations or perspectives.

The Qur'an states:

“And indeed We created man from a quintessence of clay. Then We placed within him a small quantity of nutfa (sperm to fertilize) in a safe place. Then We have fashioned the nutfa into an ‘alaqa (clinging clot or cell cluster), then We developed the ‘alaqa into mudgha (a lump of flesh), and We made mudgha into bones, and clothed the bones with flesh, then We brought it into being as a new creation. So Blessed is Allah, the Best of Creators.” [52]

Many scholars of Islam estimate the time of soul installment, marked by the angel breathing in the soul to bring the individual into creation, as 120 days from conception. [53] Personhood begins at this point, and the value of life would prohibit research or experimentation that could harm the individual. If the fetus is more than 120 days old, the time ensoulment is interpreted to occur according to Islamic law, abortion is no longer permissible. [54] There are a few opposing opinions about early embryos in Islamic traditions. According to some Islamic theologians, there is no ensoulment of the early embryo, which is the source of stem cells for ESC research. [55]

In Buddhism, the stance on stem cell research is not settled. The main tenets, the prohibition against harming or destroying others (ahimsa) and the pursuit of knowledge (prajña) and compassion (karuna), leave Buddhist scholars and communities divided. [56] Some scholars argue stem cell research is in accordance with the Buddhist tenet of seeking knowledge and ending human suffering. Others feel it violates the principle of not harming others. Finding the balance between these two points relies on the karmic burden of Buddhist morality. In trying to prevent ahimsa towards the embryo, Buddhist scholars suggest that to comply with Buddhist tenets, research cannot be done as the embryo has personhood at the moment of conception and would reincarnate immediately, harming the individual's ability to build their karmic burden. [57] On the other hand, the Bodhisattvas, those considered to be on the path to enlightenment or Nirvana, have given organs and flesh to others to help alleviate grieving and to benefit all. [58] Acceptance varies on applied beliefs and interpretations.

Catholicism does not support embryonic stem cell research, as it entails creation or destruction of human embryos. This destruction conflicts with the belief in the sanctity of life. For example, in the Old Testament, Genesis describes humanity as being created in God’s image and multiplying on the Earth, referencing the sacred rights to human conception and the purpose of development and life. In the Ten Commandments, the tenet that one should not kill has numerous interpretations where killing could mean murder or shedding of the sanctity of life, demonstrating the high value of human personhood. In other books, the theological conception of when life begins is interpreted as in utero, [59] highlighting the inviolability of life and its formation in vivo to make a religious point for accepting such research as relatively limited, if at all. [60] The Vatican has released ethical directives to help apply a theological basis to modern-day conflicts. The Magisterium of the Church states that “unless there is a moral certainty of not causing harm,” experimentation on fetuses, fertilized cells, stem cells, or embryos constitutes a crime. [61] Such procedures would not respect the human person who exists at these stages, according to Catholicism. Damages to the embryo are considered gravely immoral and illicit. [62] Although the Catholic Church officially opposes abortion, surveys demonstrate that many Catholic people hold pro-choice views, whether due to the context of conception, stage of pregnancy, threat to the mother’s life, or for other reasons, demonstrating that practicing members can also accept some but not all tenets. [63]

Some major Jewish denominations, such as the Reform, Conservative, and Reconstructionist movements, are open to supporting ESC use or research as long as it is for saving a life. [64] Within Judaism, the Talmud, or study, gives personhood to the child at birth and emphasizes that life does not begin at conception: [65]

“If she is found pregnant, until the fortieth day it is mere fluid,” [66]

Whereas most religions prioritize the status of human embryos, the Halakah (Jewish religious law) states that to save one life, most other religious laws can be ignored because it is in pursuit of preservation. [67] Stem cell research is accepted due to application of these religious laws.

We recognize that all religions contain subsets and sects. The variety of environmental and cultural differences within religious groups requires further analysis to respect the flexibility of religious thoughts and practices. We make no presumptions that all cultures require notions of autonomy or morality as under the common morality theory , which asserts a set of universal moral norms that all individuals share provides moral reasoning and guides ethical decisions. [68] We only wish to show that the interaction with morality varies between cultures and countries.

III.     A Flexible Ethical Approach

The plurality of different moral approaches described above demonstrates that there can be no universally acceptable uniform law for ESC on a global scale. Instead of developing one standard, flexible ethical applications must be continued. We recommend local guidelines that incorporate important cultural and ethical priorities.

While the Declaration of Helsinki is more relevant to people in clinical trials receiving ESC products, in keeping with the tradition of protections for research subjects, consent of the donor is an ethical requirement for ESC donation in many jurisdictions including the US, Canada, and Europe. [69] The Declaration of Helsinki provides a reference point for regulatory standards and could potentially be used as a universal baseline for obtaining consent prior to gamete or embryo donation.

For instance, in Columbia University’s egg donor program for stem cell research, donors followed standard screening protocols and “underwent counseling sessions that included information as to the purpose of oocyte donation for research, what the oocytes would be used for, the risks and benefits of donation, and process of oocyte stimulation” to ensure transparency for consent. [70] The program helped advance stem cell research and provided clear and safe research methods with paid participants. Though paid participation or covering costs of incidental expenses may not be socially acceptable in every culture or context, [71] and creating embryos for ESC research is illegal in many jurisdictions, Columbia’s program was effective because of the clear and honest communications with donors, IRBs, and related stakeholders.  This example demonstrates that cultural acceptance of scientific research and of the idea that an egg or embryo does not have personhood is likely behind societal acceptance of donating eggs for ESC research. As noted, many countries do not permit the creation of embryos for research.

Proper communication and education regarding the process and purpose of stem cell research may bolster comprehension and garner more acceptance. “Given the sensitive subject material, a complete consent process can support voluntary participation through trust, understanding, and ethical norms from the cultures and morals participants value. This can be hard for researchers entering countries of different socioeconomic stability, with different languages and different societal values. [72]

An adequate moral foundation in medical ethics is derived from the cultural and religious basis that informs knowledge and actions. [73] Understanding local cultural and religious values and their impact on research could help researchers develop humility and promote inclusion.

IV.     Concerns

Some may argue that if researchers all adhere to one ethics standard, protection will be satisfied across all borders, and the global public will trust researchers. However, defining what needs to be protected and how to define such research standards is very specific to the people to which standards are applied. We suggest that applying one uniform guide cannot accurately protect each individual because we all possess our own perceptions and interpretations of social values. [74] Therefore, the issue of not adjusting to the moral pluralism between peoples in applying one standard of ethics can be resolved by building out ethics models that can be adapted to different cultures and religions.

Other concerns include medical tourism, which may promote health inequities. [75] Some countries may develop and approve products derived from ESC research before others, compromising research ethics or drug approval processes. There are also concerns about the sale of unauthorized stem cell treatments, for example, those without FDA approval in the United States. Countries with robust research infrastructures may be tempted to attract medical tourists, and some customers will have false hopes based on aggressive publicity of unproven treatments. [76]

For example, in China, stem cell clinics can market to foreign clients who are not protected under the regulatory regimes. Companies employ a marketing strategy of “ethically friendly” therapies. Specifically, in the case of Beike, China’s leading stem cell tourism company and sprouting network, ethical oversight of administrators or health bureaus at one site has “the unintended consequence of shifting questionable activities to another node in Beike's diffuse network.” [77] In contrast, Jordan is aware of stem cell research’s potential abuse and its own status as a “health-care hub.” Jordan’s expanded regulations include preserving the interests of individuals in clinical trials and banning private companies from ESC research to preserve transparency and the integrity of research practices. [78]

The social priorities of the community are also a concern. The ISSCR explicitly states that guidelines “should be periodically revised to accommodate scientific advances, new challenges, and evolving social priorities.” [79] The adaptable ethics model extends this consideration further by addressing whether research is warranted given the varying degrees of socioeconomic conditions, political stability, and healthcare accessibilities and limitations. An ethical approach would require discussion about resource allocation and appropriate distribution of funds. [80]

While some religions emphasize the sanctity of life from conception, which may lead to public opposition to ESC research, others encourage ESC research due to its potential for healing and alleviating human pain. Many countries have special regulations that balance local views on embryonic personhood, the benefits of research as individual or societal goods, and the protection of human research subjects. To foster understanding and constructive dialogue, global policy frameworks should prioritize the protection of universal human rights, transparency, and informed consent. In addition to these foundational global policies, we recommend tailoring local guidelines to reflect the diverse cultural and religious perspectives of the populations they govern. Ethics models should be adapted to local populations to effectively establish research protections, growth, and possibilities of stem cell research.

For example, in countries with strong beliefs in the moral sanctity of embryos or heavy religious restrictions, an adaptive model can allow for discussion instead of immediate rejection. In countries with limited individual rights and voice in science policy, an adaptive model ensures cultural, moral, and religious views are taken into consideration, thereby building social inclusion. While this ethical consideration by the government may not give a complete voice to every individual, it will help balance policies and maintain the diverse perspectives of those it affects. Embracing an adaptive ethics model of ESC research promotes open-minded dialogue and respect for the importance of human belief and tradition. By actively engaging with cultural and religious values, researchers can better handle disagreements and promote ethical research practices that benefit each society.

This brief exploration of the religious and cultural differences that impact ESC research reveals the nuances of relative ethics and highlights a need for local policymakers to apply a more intense adaptive model.

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[5] Concerning the moral philosophies of stem cell research, our paper does not posit a personal moral stance nor delve into the “when” of human life begins. To read further about the philosophical debate, consider the following sources:

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[7] Socially, at its core, the Western approach to ethics is widely principle-based, autonomy being one of the key factors to ensure a fundamental respect for persons within research. For information regarding autonomy in research, see: Department of Health, Education, and Welfare, & National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (1978). The Belmont Report. Ethical principles and guidelines for the protection of human subjects of research.; For a more in-depth review of autonomy within the US, see: Beauchamp, T. L., & Childress, J. F. (1994). Principles of Biomedical Ethics . Oxford University Press.

[8] Sherley v. Sebelius , 644 F.3d 388 (D.C. Cir. 2011), citing 45 C.F.R. 46.204(b) and [42 U.S.C. § 289g(b)]. https://www.cadc.uscourts.gov/internet/opinions.nsf/6c690438a9b43dd685257a64004ebf99/$file/11-5241-1391178.pdf

[9] Stem Cell Research Enhancement Act of 2005, H. R. 810, 109 th Cong. (2001). https://www.govtrack.us/congress/bills/109/hr810/text ; Bush, G. W. (2006, July 19). Message to the House of Representatives . National Archives and Records Administration. https://georgewbush-whitehouse.archives.gov/news/releases/2006/07/20060719-5.html

[10] National Archives and Records Administration. (2009, March 9). Executive order 13505 -- removing barriers to responsible scientific research involving human stem cells . National Archives and Records Administration. https://obamawhitehouse.archives.gov/the-press-office/removing-barriers-responsible-scientific-research-involving-human-stem-cells

[11] Hurlbut, W. B. (2006). Science, Religion, and the Politics of Stem Cells.  Social Research ,  73 (3), 819–834. http://www.jstor.org/stable/40971854

[12] Akpa-Inyang, Francis & Chima, Sylvester. (2021). South African traditional values and beliefs regarding informed consent and limitations of the principle of respect for autonomy in African communities: a cross-cultural qualitative study. BMC Medical Ethics . 22. 10.1186/s12910-021-00678-4.

[13] Source for further reading: Tangwa G. B. (2007). Moral status of embryonic stem cells: perspective of an African villager. Bioethics , 21(8), 449–457. https://doi.org/10.1111/j.1467-8519.2007.00582.x , see also Mnisi, F. M. (2020). An African analysis based on ethics of Ubuntu - are human embryonic stem cell patents morally justifiable? African Insight , 49 (4).

[14] Jecker, N. S., & Atuire, C. (2021). Bioethics in Africa: A contextually enlightened analysis of three cases. Developing World Bioethics , 22 (2), 112–122. https://doi.org/10.1111/dewb.12324

[15] Jecker, N. S., & Atuire, C. (2021). Bioethics in Africa: A contextually enlightened analysis of three cases. Developing World Bioethics, 22(2), 112–122. https://doi.org/10.1111/dewb.12324

[16] Jackson, C.S., Pepper, M.S. Opportunities and barriers to establishing a cell therapy programme in South Africa.  Stem Cell Res Ther   4 , 54 (2013). https://doi.org/10.1186/scrt204 ; Pew Research Center. (2014, May 1). Public health a major priority in African nations . Pew Research Center’s Global Attitudes Project. https://www.pewresearch.org/global/2014/05/01/public-health-a-major-priority-in-african-nations/

[17] Department of Health Republic of South Africa. (2021). Health Research Priorities (revised) for South Africa 2021-2024 . National Health Research Strategy. https://www.health.gov.za/wp-content/uploads/2022/05/National-Health-Research-Priorities-2021-2024.pdf

[18] Oosthuizen, H. (2013). Legal and Ethical Issues in Stem Cell Research in South Africa. In: Beran, R. (eds) Legal and Forensic Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32338-6_80 , see also: Gaobotse G (2018) Stem Cell Research in Africa: Legislation and Challenges. J Regen Med 7:1. doi: 10.4172/2325-9620.1000142

[19] United States Bureau of Citizenship and Immigration Services. (1998). Tunisia: Information on the status of Christian conversions in Tunisia . UNHCR Web Archive. https://webarchive.archive.unhcr.org/20230522142618/https://www.refworld.org/docid/3df0be9a2.html

[20] Gaobotse, G. (2018) Stem Cell Research in Africa: Legislation and Challenges. J Regen Med 7:1. doi: 10.4172/2325-9620.1000142

[21] Kooli, C. Review of assisted reproduction techniques, laws, and regulations in Muslim countries.  Middle East Fertil Soc J   24 , 8 (2020). https://doi.org/10.1186/s43043-019-0011-0 ; Gaobotse, G. (2018) Stem Cell Research in Africa: Legislation and Challenges. J Regen Med 7:1. doi: 10.4172/2325-9620.1000142

[22] Pang M. C. (1999). Protective truthfulness: the Chinese way of safeguarding patients in informed treatment decisions. Journal of medical ethics , 25(3), 247–253. https://doi.org/10.1136/jme.25.3.247

[23] Wang, L., Wang, F., & Zhang, W. (2021). Bioethics in China’s biosecurity law: Forms, effects, and unsettled issues. Journal of law and the biosciences , 8(1).  https://doi.org/10.1093/jlb/lsab019 https://academic.oup.com/jlb/article/8/1/lsab019/6299199

[24] Wang, Y., Xue, Y., & Guo, H. D. (2022). Intervention effects of traditional Chinese medicine on stem cell therapy of myocardial infarction.  Frontiers in pharmacology ,  13 , 1013740. https://doi.org/10.3389/fphar.2022.1013740

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[28] Zhang, J. Y. (2017). Lost in translation? accountability and governance of Clinical Stem Cell Research in China. Regenerative Medicine , 12 (6), 647–656. https://doi.org/10.2217/rme-2017-0035

[29] Wang, L., Wang, F., & Zhang, W. (2021). Bioethics in China’s biosecurity law: Forms, effects, and unsettled issues. Journal of law and the biosciences , 8(1).  https://doi.org/10.1093/jlb/lsab019 https://academic.oup.com/jlb/article/8/1/lsab019/6299199

[30] Chen, H., Wei, T., Wang, H.  et al.  Association of China’s two-child policy with changes in number of births and birth defects rate, 2008–2017.  BMC Public Health   22 , 434 (2022). https://doi.org/10.1186/s12889-022-12839-0

[31] Azuma, K. Regulatory Landscape of Regenerative Medicine in Japan.  Curr Stem Cell Rep   1 , 118–128 (2015). https://doi.org/10.1007/s40778-015-0012-6

[32] Harris, R. (2005, May 19). Researchers Report Advance in Stem Cell Production . NPR. https://www.npr.org/2005/05/19/4658967/researchers-report-advance-in-stem-cell-production

[33] Park, S. (2012). South Korea steps up stem-cell work.  Nature . https://doi.org/10.1038/nature.2012.10565

[34] Resnik, D. B., Shamoo, A. E., & Krimsky, S. (2006). Fraudulent human embryonic stem cell research in South Korea: lessons learned.  Accountability in research ,  13 (1), 101–109. https://doi.org/10.1080/08989620600634193 .

[35] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6

[36] Association for the Advancement of Blood and Biotherapies.  https://www.aabb.org/regulatory-and-advocacy/regulatory-affairs/regulatory-for-cellular-therapies/international-competent-authorities/saudi-arabia

[37] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia.  BMC medical ethics ,  21 (1), 35. https://doi.org/10.1186/s12910-020-00482-6

[38] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia. BMC medical ethics , 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6

Culturally, autonomy practices follow a relational autonomy approach based on a paternalistic deontological health care model. The adherence to strict international research policies and religious pillars within the regulatory environment is a great foundation for research ethics. However, there is a need to develop locally targeted ethics approaches for research (as called for in Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6), this decision-making approach may help advise a research decision model. For more on the clinical cultural autonomy approaches, see: Alabdullah, Y. Y., Alzaid, E., Alsaad, S., Alamri, T., Alolayan, S. W., Bah, S., & Aljoudi, A. S. (2022). Autonomy and paternalism in Shared decision‐making in a Saudi Arabian tertiary hospital: A cross‐sectional study. Developing World Bioethics , 23 (3), 260–268. https://doi.org/10.1111/dewb.12355 ; Bukhari, A. A. (2017). Universal Principles of Bioethics and Patient Rights in Saudi Arabia (Doctoral dissertation, Duquesne University). https://dsc.duq.edu/etd/124; Ladha, S., Nakshawani, S. A., Alzaidy, A., & Tarab, B. (2023, October 26). Islam and Bioethics: What We All Need to Know . Columbia University School of Professional Studies. https://sps.columbia.edu/events/islam-and-bioethics-what-we-all-need-know

[39] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics.  Research Ethics ,  17 (2), 228-241.  https://doi.org/10.1177/1747016120966779

[40] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics.  Research Ethics ,  17 (2), 228-241.  https://doi.org/10.1177/1747016120966779

[41] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[42] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[43] The EU’s definition of autonomy relates to the capacity for creating ideas, moral insight, decisions, and actions without constraint, personal responsibility, and informed consent. However, the EU views autonomy as not completely able to protect individuals and depends on other principles, such as dignity, which “expresses the intrinsic worth and fundamental equality of all human beings.” Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3

[44] Council of Europe. Convention for the protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine: Convention on Human Rights and Biomedicine (ETS No. 164) https://www.coe.int/en/web/conventions/full-list?module=treaty-detail&treatynum=164 (forbidding the creation of embryos for research purposes only, and suggests embryos in vitro have protections.); Also see Drabiak-Syed B. K. (2013). New President, New Human Embryonic Stem Cell Research Policy: Comparative International Perspectives and Embryonic Stem Cell Research Laws in France.  Biotechnology Law Report ,  32 (6), 349–356. https://doi.org/10.1089/blr.2013.9865

[45] Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3

[46] Tomuschat, C., Currie, D. P., Kommers, D. P., & Kerr, R. (Trans.). (1949, May 23). Basic law for the Federal Republic of Germany. https://www.btg-bestellservice.de/pdf/80201000.pdf

[47] Regulation of Stem Cell Research in Germany . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-germany

[48] Regulation of Stem Cell Research in Finland . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-finland

[49] Regulation of Stem Cell Research in Spain . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-spain

[50] Some sources to consider regarding ethics models or regulatory oversights of other cultures not covered:

Kara MA. Applicability of the principle of respect for autonomy: the perspective of Turkey. J Med Ethics. 2007 Nov;33(11):627-30. doi: 10.1136/jme.2006.017400. PMID: 17971462; PMCID: PMC2598110.

Ugarte, O. N., & Acioly, M. A. (2014). The principle of autonomy in Brazil: one needs to discuss it ...  Revista do Colegio Brasileiro de Cirurgioes ,  41 (5), 374–377. https://doi.org/10.1590/0100-69912014005013

Bharadwaj, A., & Glasner, P. E. (2012). Local cells, global science: The rise of embryonic stem cell research in India . Routledge.

For further research on specific European countries regarding ethical and regulatory framework, we recommend this database: Regulation of Stem Cell Research in Europe . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-europe   

[51] Klitzman, R. (2006). Complications of culture in obtaining informed consent. The American Journal of Bioethics, 6(1), 20–21. https://doi.org/10.1080/15265160500394671 see also: Ekmekci, P. E., & Arda, B. (2017). Interculturalism and Informed Consent: Respecting Cultural Differences without Breaching Human Rights.  Cultura (Iasi, Romania) ,  14 (2), 159–172.; For why trust is important in research, see also: Gray, B., Hilder, J., Macdonald, L., Tester, R., Dowell, A., & Stubbe, M. (2017). Are research ethics guidelines culturally competent?  Research Ethics ,  13 (1), 23-41.  https://doi.org/10.1177/1747016116650235

[52] The Qur'an  (M. Khattab, Trans.). (1965). Al-Mu’minun, 23: 12-14. https://quran.com/23

[53] Lenfest, Y. (2017, December 8). Islam and the beginning of human life . Bill of Health. https://blog.petrieflom.law.harvard.edu/2017/12/08/islam-and-the-beginning-of-human-life/

[54] Aksoy, S. (2005). Making regulations and drawing up legislation in Islamic countries under conditions of uncertainty, with special reference to embryonic stem cell research. Journal of Medical Ethics , 31: 399-403.; see also: Mahmoud, Azza. "Islamic Bioethics: National Regulations and Guidelines of Human Stem Cell Research in the Muslim World." Master's thesis, Chapman University, 2022. https://doi.org/10.36837/ chapman.000386

[55] Rashid, R. (2022). When does Ensoulment occur in the Human Foetus. Journal of the British Islamic Medical Association , 12 (4). ISSN 2634 8071. https://www.jbima.com/wp-content/uploads/2023/01/2-Ethics-3_-Ensoulment_Rafaqat.pdf.

[56] Sivaraman, M. & Noor, S. (2017). Ethics of embryonic stem cell research according to Buddhist, Hindu, Catholic, and Islamic religions: perspective from Malaysia. Asian Biomedicine,8(1) 43-52.  https://doi.org/10.5372/1905-7415.0801.260

[57] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[58] Lecso, P. A. (1991). The Bodhisattva Ideal and Organ Transplantation.  Journal of Religion and Health ,  30 (1), 35–41. http://www.jstor.org/stable/27510629 ; Bodhisattva, S. (n.d.). The Key of Becoming a Bodhisattva . A Guide to the Bodhisattva Way of Life. http://www.buddhism.org/Sutras/2/BodhisattvaWay.htm

[59] There is no explicit religious reference to when life begins or how to conduct research that interacts with the concept of life. However, these are relevant verses pertaining to how the fetus is viewed. (( King James Bible . (1999). Oxford University Press. (original work published 1769))

Jerimiah 1: 5 “Before I formed thee in the belly I knew thee; and before thou camest forth out of the womb I sanctified thee…”

In prophet Jerimiah’s insight, God set him apart as a person known before childbirth, a theme carried within the Psalm of David.

Psalm 139: 13-14 “…Thou hast covered me in my mother's womb. I will praise thee; for I am fearfully and wonderfully made…”

These verses demonstrate David’s respect for God as an entity that would know of all man’s thoughts and doings even before birth.

[60] It should be noted that abortion is not supported as well.

[61] The Vatican. (1987, February 22). Instruction on Respect for Human Life in Its Origin and on the Dignity of Procreation Replies to Certain Questions of the Day . Congregation For the Doctrine of the Faith. https://www.vatican.va/roman_curia/congregations/cfaith/documents/rc_con_cfaith_doc_19870222_respect-for-human-life_en.html

[62] The Vatican. (2000, August 25). Declaration On the Production and the Scientific and Therapeutic Use of Human Embryonic Stem Cells . Pontifical Academy for Life. https://www.vatican.va/roman_curia/pontifical_academies/acdlife/documents/rc_pa_acdlife_doc_20000824_cellule-staminali_en.html ; Ohara, N. (2003). Ethical Consideration of Experimentation Using Living Human Embryos: The Catholic Church’s Position on Human Embryonic Stem Cell Research and Human Cloning. Department of Obstetrics and Gynecology . Retrieved from https://article.imrpress.com/journal/CEOG/30/2-3/pii/2003018/77-81.pdf.

[63] Smith, G. A. (2022, May 23). Like Americans overall, Catholics vary in their abortion views, with regular mass attenders most opposed . Pew Research Center. https://www.pewresearch.org/short-reads/2022/05/23/like-americans-overall-catholics-vary-in-their-abortion-views-with-regular-mass-attenders-most-opposed/

[64] Rosner, F., & Reichman, E. (2002). Embryonic stem cell research in Jewish law. Journal of halacha and contemporary society , (43), 49–68.; Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[65] Schenker J. G. (2008). The beginning of human life: status of embryo. Perspectives in Halakha (Jewish Religious Law).  Journal of assisted reproduction and genetics ,  25 (6), 271–276. https://doi.org/10.1007/s10815-008-9221-6

[66] Ruttenberg, D. (2020, May 5). The Torah of Abortion Justice (annotated source sheet) . Sefaria. https://www.sefaria.org/sheets/234926.7?lang=bi&with=all&lang2=en

[67] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[68] Gert, B. (2007). Common morality: Deciding what to do . Oxford Univ. Press.

[69] World Medical Association (2013). World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA , 310(20), 2191–2194. https://doi.org/10.1001/jama.2013.281053 Declaration of Helsinki – WMA – The World Medical Association .; see also: National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. (1979).  The Belmont report: Ethical principles and guidelines for the protection of human subjects of research . U.S. Department of Health and Human Services.  https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report/read-the-belmont-report/index.html

[70] Zakarin Safier, L., Gumer, A., Kline, M., Egli, D., & Sauer, M. V. (2018). Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes.  Journal of assisted reproduction and genetics ,  35 (7), 1219–1225. https://doi.org/10.1007/s10815-018-1171-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063839/ see also: Riordan, N. H., & Paz Rodríguez, J. (2021). Addressing concerns regarding associated costs, transparency, and integrity of research in recent stem cell trial. Stem Cells Translational Medicine , 10 (12), 1715–1716. https://doi.org/10.1002/sctm.21-0234

[71] Klitzman, R., & Sauer, M. V. (2009). Payment of egg donors in stem cell research in the USA.  Reproductive biomedicine online ,  18 (5), 603–608. https://doi.org/10.1016/s1472-6483(10)60002-8

[72] Krosin, M. T., Klitzman, R., Levin, B., Cheng, J., & Ranney, M. L. (2006). Problems in comprehension of informed consent in rural and peri-urban Mali, West Africa.  Clinical trials (London, England) ,  3 (3), 306–313. https://doi.org/10.1191/1740774506cn150oa

[73] Veatch, Robert M.  Hippocratic, Religious, and Secular Medical Ethics: The Points of Conflict . Georgetown University Press, 2012.

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[75] Pirzada, N. (2022). The Expansion of Turkey’s Medical Tourism Industry.  Voices in Bioethics ,  8 . https://doi.org/10.52214/vib.v8i.9894

[76] Stem Cell Tourism: False Hope for Real Money . Harvard Stem Cell Institute (HSCI). (2023). https://hsci.harvard.edu/stem-cell-tourism , See also: Bissassar, M. (2017). Transnational Stem Cell Tourism: An ethical analysis.  Voices in Bioethics ,  3 . https://doi.org/10.7916/vib.v3i.6027

[77] Song, P. (2011) The proliferation of stem cell therapies in post-Mao China: problematizing ethical regulation,  New Genetics and Society , 30:2, 141-153, DOI:  10.1080/14636778.2011.574375

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[80] Benjamin, R. (2013). People’s science bodies and rights on the Stem Cell Frontier . Stanford University Press.

Mifrah Hayath

SM Candidate Harvard Medical School, MS Biotechnology Johns Hopkins University

Olivia Bowers

MS Bioethics Columbia University (Disclosure: affiliated with Voices in Bioethics)

Article Details

This work is licensed under a Creative Commons Attribution 4.0 International License .

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